Yini ebangela isifo sikashukela

Isifo sikashukela siyingozi yangempela ebuntwini besimanje. Izinga eliphakeme lokufudukela kwabantu emadolobheni, izingcindezi ezivame kakhulu nokuphila kokuhlala phansi zisho izimo ezintsha kithi, kwesinye isikhathi eziholela emiphumeleni emibi yempilo. Eminyakeni engamashumi amabili edlule, inani labantu abanesifo sikashukela likhuphuke kaningi ngaphezulu. Ngakho-ke yini eholela kulesi sifo esibi kangaka se-endocrine? Yini ebangela isifo sikashukela nokuthi ungabhekana kanjani nayo? Sizozama ukuphendula le mibuzo neminye esihlokweni esingezansi.

Imbangela enkulu yesifo sikashukela ukusetshenziswa koshukela abahlanjululwe.

Izinhlobo zesifo sikashukela

Ngaphambi kokuthi uthole ukuthi kungani isifo sikashukela senzeka, kufanele uqonde ukuthi yiziphi izinhlobo zalesi sifo ezitholakala. Kunezinhlobo eziningi zesifo sikashukela kanye nezimbangela zokuvela kwazo ezinhlobonhlobo zezifo zihluka kakhulu komunye nomunye. Ngaphandle kwezimpawu ezifanayo, izinqubo ze-pathogenetic ezinhlotsheni ezahlukahlukene zesifo sikashukela futhi ngokuya ngobulili nobudala zingahluka kakhulu. Ezikhathini zanamuhla zokwelashwa, ama-endocrinologists ahlukanisa izinhlobo ezintathu ezibaluleke kakhulu nezivamile zoshukela:

• Thayipha isifo sikashukela sokuqala esingu-1 noma uhlobo lwesifo esincike e-insulin.
• Thayipha isifo sikashukela esingu-2 noma ifomu lesifo elivimbela i-insulin.
• Isifo sikashukela sokutholwa komzimba noma uhlobo oluthile lwabesifazane abakhulelwe.

Kunobudlelwano obuthile phakathi kwezinto ezifana nobudlova, ubulili nobudala, isimo senhlalo, indlela yokuphila nezinye izinto eziningi lesi sifo esingenzeka ngaso. Ukuphazamiseka kwe-Endocrine kungacasulwa noma yinto eyodwa enamandla noma ukuhlanganiswa okuncane, okuholela ekugcineni ekubumbeni nasekuphazanyisweni kwe-hormone homeostasis kanye nezinqubo ze-metabolic emzimbeni.

Izinhlobo Zobungozi Besifo Sikashukela sohlobo 2

Izici zobungozi

Umuntu ojwayelekile wesimanje uboshelwa ngokoqobo nazo zonke izinhlobo zezinto ezingezinhle futhi ezilimazayo. Kuyisiko ukwahlukanisa amaqembu amabili ayinhloko yezinto eziyingozi ezithinta izinqubo ze-metabolic emzimbeni womuntu.

Izici ezingenakufinyeleleka

Iqembu lokuqala lifaka izinto ezingancike entandweni nasemizameni yomuntu, angeke ziguqulwe, kepha kufanele zibhekwe, uma zikhona. Izici ezinjalo zibandakanya, iqiniso, isifiso sokuqalwa kwesifo sikashukela.

Sivelaphi iswekile yabantu abadala? Ososayensi balinganisela ukuthi okungenani i-30% yengozi yokuthola isifo sesifo sikashukela sohlobo 2 sincike emlandweni womndeni onesisindo. Uma umndeni wezihlobo eziseduzane, njengonina nobaba, unalesi sifo se-endocrine, khona-ke ingozi yokuba nesifo sikashukela inyuka kakhulu.

I-Heredity yinto ebaluleke kakhulu engaguquki engabikwa, kodwa kude kuphela kwento. Okubaluleke kancane, kepha okwenzekayo kungabikwa ezintweni ezingenakuphikwa njengoku:

Yini imbangela yesifo sikashukela?

• Ukuzihlanganisa nobuhlanga. Abamele lezi zinhlanga ezilandelayo bafanele iRussia Federation: AmaBuryats, amaCaucasians, amaTuva kanye nabantu abahlukahlukene basenyakatho. Lezi zizwe zithambekele kakhudlwana ekuthuthukiseni ukuphazamiseka kwe-metabolic, ikakhulukazi, kusukela ohlangothini lwe-carbohydrate metabolism. Inani elincane lezinto ezilimazayo lingavusa ukukhula kwesifo emazweni anjalo.
• Iminyaka. Akekho umuntu ongathonya isikhathi futhi, ngeshwa, ubudala budlala indima ebalulekile ekwakhiweni kwesifo sikashukela. Ngemuva kweminyaka engama-25, ubungozi bokuthola ukuphazamiseka kwe-dysmetabolic banda cishe kabili.
• Ubulili Sekuyisikhathi eside kwaziwa ukuthi ingxenye yesilisa yabantu inalesi sifo kaningi ukwedlula yowesifazane futhi lokhu kumele kubhekwe nakho!

Zonke lezi zinto ezingaba zengozi ezingenakulinganiswa ezingenhla, noma zingancikile kithi, zingabhekwa, futhi indlela yokuphila nenempilo ehlanganiswe nokudla okunengqondo nokulinganiselayo inganciphisa kakhulu ingozi yokugula okungathi sína njengesifo sikashukela.

Izici Ezilungisekayo

Izici ezingashintshi izinqubo umuntu akwazi ukuzikhipha noma azilungise. Ngezindlela eziningi, yizici ezingaguquguqukayo eziba yisizathu esiyinhloko esingadala isifo sikashukela sohlobo oluthile noma kwesinye.

Ukungakhathaleli impilo yakho kuyisizathu esiyisisekelo sokuthuthukisa noma yiluphi uhlobo lwesifo sikashukela!

Indlela yokuphila engalungile nokucabanga komuntu wanamuhla kuholela emiphumeleni emibi kakhulu! Izici ezibalulekile zobungozi ezingashintshwa zibandakanya:

• Ukuntuleka kokuzivocavoca. Indlela yokuphila yokuhlala phansi, umsebenzi wokuhlala ehhovisi, ukuhamba ngemoto, ukuvilapha kwe-banal - enye yezinsika ezintathu zesifo sikashukela. Uma kungekho noma ukungasebenzi kahle komzimba, ukusetshenziswa kwamandla komzimba kuyehla. Lokhu kuholela ekungalingani phakathi kokudla okuqediwe nenani lamandla ayo kanye nezindleko zomzimba walawa mandla. I-Hypodynamia, ngaphezu kwalokho, iholela ku-hypotrophy yezicubu zomzimba, iphinde isheshise ukuthuthukiswa kokukhuluphala kanye ne-metabolic syndrome.
• Ukuhlukumeza. Isici esiyinhloko sokukhuluphala kanye nokuqala kwesifo sikashukela kuyindlela elwa ne-insulin. Ukweqile kuholela ebangeni lamandla emzimbeni, angakwazi ukuchitha, la mandla agcinwa emzimbeni ngesimo sezicubu ze-adipose.
• Ukunakwa empilweni. Ukutheleleka okuthe njalo okubandayo kanye nokubanda kuyimbangela eyinhloko yokwanda kwesifo sikashukela sohlobo 1. Ukulimazeka kumanyikwe ngamakhondomu ngokwawo kubangelwa izifo ezithathelwanayo ezihlala njalo.

Izizathu

Sivela kuphi isifo sikashukela? Ungasithola kanjani isifo sikashukela, uyabuza? Yebo, kulula kakhulu! Udinga nje ukuhlala uthule ungenzi lutho, kepha vele udle futhi ube ngamavila noma uvame ukugula nge-tonsillitis kanye nokunye ukubanda. Indlela yokuphila engalungile izolulaza umzimba wakho kancane futhi iholele ekulinganiseni kwazo zonke izinhlobo zezinqubo ze-metabolic kuyo. Kungani kuvela isifo sikashukela? Ngohlobo ngalunye lwesifo, impendulo izoba ehlukile, ake sihlaziye ngokulandelana.

Thayipha i-insulin engu-1

Le nketho yenzeka kaningi ezinganeni. Kungani kwenzeka isifo sikashukela sohlobo 1? Ngezifo ezihlasela njalo zokuphefumula ezibangelwa amagciwane noma amagciwane, amasosha omzimba angasebenzi kahle futhi aqale ukukhiqiza amasosha omzimba hhayi nje kuphela kuma-ejenti athelelekayo, kodwa nasezithanjeni zawo. Okunye kwalokhu okuhlosiwe ngamaseli e-beta esiqhingini saseLangerhans asemaphashini. Le nqubo ibizwa nge-autoimmune, isb., Amasosha akho omzimba aqala ukubhubhisa umzimba wakho.

Ukulimala kumanyikwe kuyimbangela eyinhloko yesifo sikashukela sohlobo 1.

Ngokubhujiswa okungaphezu kwamaphesenti angama-90 amaseli we-beta akhiqiza i-insulin, i-carbohydrate metabolism isebolile futhi kuvela isithombe sezempilo sohlobo 1 sikashukela. Isifo sikashukela sohlobo loku-1 siqala ngokungenaphutha, uphawu oluphambili ukulahleka kwesisindo kwengane okubangelwa ukushoda kwe-glucose kumaseli womzimba. Iqiniso ngukuthi i-insulin iluhlobo lokukhala oluvumela i-glucose, umsoco oyinhloko, ukungena kumaseli ngokukhula nokwahlukana kwabo. Ngokushoda kwe-insulin, ushukela unqwabelana egazini, futhi amaseli aqala ukuzwa indlala, ebangela izinqubo ze-dystrophic. Ngaphandle, lokhu kuboniswa ukwehla kwesisindo okubukhali kanye nobuthakathaka obujwayelekile.

Uhlobo oluzimele lwe-non-insulin 2

Lolu hlobo lwesifo sikashukela luvame ukutholakala kubantu abadala, kodwa futhi lungaba kubantu abasha. Yini ebangela isifo sikashukela sohlobo 2? Uhlobo 2 sikashukela i-mellitus sikhula kancane futhi ingahlala ingabonakali kumuntu ogulayo nayo. Kulokhu, izici ezinjengokulifa, indlela yokuphila engafanele eholela ekungasebenzi kahle komzimba kanye nokukhuluphala, kanye nokuba khona kwemikhuba emibi kudlala indima enkulu ekuqaleni kwesifo sikashukela. Ngokungalingani kahle phakathi kwezindleko zamandla asetshenzisiwe nezamandla, kukhona ukwanda okukhulu kwama-adipocytes - amaseli we-adipose izicubu. Ukukhuluphala kuholela ekuphazanyisweni kwebhalansi ye-hormonal emzimbeni, futhi amakhemikhali ahlanganisiwe we-atypical for the hali yezomzimba aqala ukukhiqizwa.

Ukukhuluphala kuhambisana nokumelana ne-insulin, okubangela isifo sikashukela sohlobo 2

Izicubu ze-adipose ngokweqile zakha ukumelana kwamanye izicubu kwe-insulin. Ngakho-ke, i-insulin kuqala iqala ukukhiqizwa kakhulu iphendula ekuxhakazelweni okukhulu kwe-glucose egazini, bese amaseli we-pancreatic beta ancishisiwe, bese kuthi ukugcinwa kwe-insulin kunciphe futhi kuholele ekuqhubekeni kwesifo.

Isibonakaliso esiyinhloko sohlobo lwe-insulin engamelana nesifo sikashukela ukuchama ngokushesha, ukunxephezela i-hyperglycemia yegazi. Lolu hlobo lwesifo luvame ukutholwa kakhulu lapho kwenziwa izifundo zokutholwa kwezifo zokuvimbela izifo, lapho ukunqwabelana kwe-glucose ku-plasma yegazi kunqunywa. Ngaphezu kokuchama okuvamisile, uphawu oluvelele kunazo zonke lwefomu elimelana ne-insulin ukulunywa esikhunjeni kanye nezifo ezithinta ukuqubuka kwesikhumba ezingapholi isikhathi eside.

Uhlobo lomzimba

Kwenzeka kubantu besifazane kuphela futhi kunendlela eyinkimbinkimbi yokuqamba. Okudala sikashukela okukhulelwe ngumbuzo onzima. Ngezindlela eziningi, izimbangela zesifo sikashukela kwabesifazane abakhulelwe bezingakasungulwa, kepha ubuhlobo phakathi kokukhulelwa kanye nokwehla komkhiqizo we-insulin sekusunguliwe. Ochwepheshe abaningi bayavuma ukuthi imbangela eyinhloko yohlobo lokuthinta umzimba kungukuphindwa kabusha kokuklanywa kabusha komzimba womuntu wesifazane ngesikhathi sokukhulelwa nokukhishwa, lapho kwezinye izimo kungaholela ekucindezelweni kokugcina kwe-insulin ngamaseli we-pancreatic beta.