I-Glipizide (Glipizide) - imiyalo esetshenziswayo, i-analogues

Phakathi kwezidakamizwa ezisetshenziswa ekwelapheni isifo sikashukela zingabizwa ngokuthi yi-Glipizide (Glipizide). Leli thuluzi lihloselwe ukuhlela amazinga kashukela egazini ngokwejwayelekile.

Inkomba yokwanda kashukela ibangela ukuphazamiseka emzimbeni, yingakho kuvela ubunzima. Ukuze umuthi usebenze ngempumelelo, kufanele wazi izici zawo nemithetho yokusebenzisa.

Imininingwane ejwayelekile mayelana nalokhu

Into ye-formula glipizide

I-Glipizide yigama eliyinhloko lokuhweba lesidakamizwa esiqukethe into enegama elifanayo, kepha liyingxenye yezinye izidakamizwa.

Ingxenye ibonakala ngomphumela obizwa ngokuthi yi-hypoglycemic, otholakala ngenxa yomthelela wawo kumaseli we-pancreatic. Umphumela walokhu ukuhlanganiswa okusebenzayo kwe-insulin.

Umuthi umelelwa ngofulawa omhlophe ngaphandle kwephunga elishiwoyo. Ayibonakali nge-solubility emanzini noma yotshwala. Ingxenye isebenza ngokubambisana namaprotheni egazi, iguqulwa ibe ngama-metabolites. I-Excretion yenziwa izinso.

I-Glipizide ikhiqizwa ezibhebheni ezinokuqukethwe kwezidakamizwa okusebenzayo okungu-5 no-10 mg. Izakhi ezisizayo zingahluka ngokuya ngegama lomuthi.

Imiyalo yokusebenzisa

Umuthi kuhloswe ngawo ukulwa nesifo sikashukela sohlobo 2, uma izindlela zokwelapha ezingezona izidakamizwa zilethi imiphumela.

Izibhebhe ziphuza ngomlomo, ngaphambi nje kokudla, ngomuthi onamanzi. Umthamo uncike ezimweni eziqondene nesiguli. Kuvame ukunconywa ukuqala ngokukhishwa kwe-5 mg ngosuku.

Ngokusebenza okunganele kanye nokubekezelela okuhle komuthi, umthamo ungakhuphuka kancane kancane ufike ku-15 mg ngosuku. Kuvunyelwe ukuthatha umuthi ngesikhathi, ungahlukanisa nokukhonza ube ngamalitha amaningi.

Kwezinye izimo, isilinganiso se-Glipizide kufanele sehliswe. Ngakho-ke, ukwelashwa akufanele kuqale ngaphandle kokunconywa uchwepheshe - ngaphandle kolwazi lwezokwelapha kunzima kakhulu ukuhlola izici zesithombe sasemtholampilo.

Ukweqa amaphilisi kuyinto engathandeki, kodwa uma lokhu kwenzeka, ungathathi umthamo ophindwe kabili.

Contraindication kanye nomonakalo ongaba khona

Ngaphandle kwezinzuzo zalo muthi zesifo sikashukela, kukhona amacala lapho ukusetshenziswa kwawo kwenqatshelwe.

I-contraindication eyinhloko ye-Glipizide ifaka:

• ukungabekezeleli ekwakhekeni;
• i-ketoacidosis ebangelwa isifo sikashukela;
• isifo sikashukela;
• ukukhulelwa
• ukondla kwemvelo;
• Uhlobo 1 sikashukela;
• ukungenelela kokuhlinzwa;
• ukulimala okungathi sína;
• umkhuhlane.

Ukuvinjwa kokusetshenziswa kwomuthi kungenxa yengozi yemiphumela engathandeki engahle yenzeke.

Phakathi kwazo khuluma:

• ikhanda
• Isiyezi
• ukukhathala;
• ukozela
• ukudangala komoya;
• ukudideka kokwazi;
• Ukukhathazeka
• i-conjunctivitis;
• izinhlungu emehlweni;
• i-retinal hemorrhage;
• ukwephulwa kwamgudu wokugaya ukudla;
• isicanucanu
• i-urticaria;
• ukulunywa
• imivimbo yesikhumba;
• i-rhinitis;
• ukwanda kwengcindezi;
• arrhythmia;
• kwehla i-libido;
• ukukhuphuka kokujuluka;
• hypoglycemia

Okuningi kwalokhu kwephula umthetho akuyona ingozi, kepha kuletha ukungakhululeki okuhle. Abanye bangenza nokuthi isiguli sife uma singanikezwa ukunakekelwa kwezokwelashwa. Ngakho-ke, ngaphambi kokusebenzisa izidakamizwa eziqukethe i-glipizide, kufanele uthintane nodokotela wakho futhi uthole ukuthi ungazisebenzisa kanjani ngokufanele. Kodwa noma ngabe ikhambi selinqunyelwe uchwepheshe, udinga ukubhekisisa inhlala-kahle yakho. Ukuthola izimpawu ezingezinhle kuyisizathu sokufuna usizo.

Ama-Analog

Umuthi okukhulunywa ngawo awuvunyelwa njalo ukuthi usetshenziswe. Uma kukhona ama-contraindication, kuyadingeka ukubuyisa okunye, ngesakhiwo esehlukile.

Phakathi kokufana okuyinhloko kweGlipizide yilezi:

1. I-Glibenclamide. Umuthi usekwe ku-glibenclamide. Isetshenziselwa ukunciphisa ushukela wegazi. Umuthi ukwindlela yamathebulethi, uhanjiswa ngomlomo. Izindleko - kusuka kuma-ruble angama-80 kuye kwangama-90.
2. Ibhisogma. Isakhi esiyinhloko salo muthi yi-gliclazide. I-Bisogma yenzelwe ukulwa ne-mellitus engavikelekile nge-insulin. Kuthengiswa ezibhebheni ngenani lama-ruble angama-85-110.
3. I-Glimepiride. Isithako sayo esisebenzayo yi-glimepiride. Uhlobo lokukhishwa kwayo kungamathebulethi. Umkhiqizo unomphumela wehlisela ushukela, ngoba uvuselela ukukhiqizwa kwe-insulin. Umuthi ungathengwa ngenani lama-ruble angama-95 kuye kwangama-120.
4. UMinidiab. Umuthi ubonakala ngomphumela we-hypoglycemic, otholakala ngenxa yokuqukethwe kwe-glipizide kuwo. Lokhu kusho ukuthi iMinidiab iyi-analogue ephelele yamacwecwe acatshangwayo ekwakhekeni, futhi imiyalelo yawo iyefana. Umuthi uphakathi kwababizayo, kuzodingeka ukhokhe ama-ruble ayi-1,500 wokuwaphaka.
5. I-Metformin. Isithako sayo esisebenzayo yi-metformin. Kuyaphazamisa ukukhiqizwa kwe-glucose okusebenzayo ngesibindi, futhi futhi kwandise amathuba okuthi izicubu zihambisane ne-insulin. Umuthi uyathengiswa ngendlela yamaphilisi ngezindleko zama-ruble angama-90- 105.
6. Maninil. Isisekelo salo muthi yi-glibenclamide. Ukukhishwa kwayo kuzoba ngokungacabangi ngendlela yethebhulethi. Ngaphezu kwe-hypoglycemic, inomphumela we-cardioprotective and antiarrhythmic. Intengo iyahlukahluka kusuka kuma-ruble angama-95 kuya kwangama-120.
7. I-Glucophage. Isithako saso esiyinhloko yi-metformin. Umuthi unefomu lethebhulethi, okuhloswe ngalo ukuphathwa ngomlomo. Inomphumela wemvelo we-hypoglycemic. Bathengiswa ngokuya ngemiyalelo kadokotela ngenani lama-ruble angaba ngu-120.
8. UGlidiab. Lokhu kungenye i-analogue eyinhlanganisela enento efanayo esebenzayo. Ikhuthaza ukuhlanganiswa kwe-insulin emzimbeni, ngaleyo ndlela kunciphise ushukela wegazi. Izindleko zingama-ruble ayi-100-120.

Ividiyo evela kusazi:

Yonke le mishanguzo ingadala imiphumela emibi, okuyingozi kunazo zonke okuyi-hypoglycemia. Futhi banokuphambana. Ngakho-ke, kufanele zisetshenziswe kuphela ngemvume kadokotela nangokuyalelwa. Ukukhetha umuntu obambela umuthi obekiwe ngokwakho akuvunyelwe, kungaba yingozi.