Imiyalo yokusebenzisa isidakamizwa uSiofor

Ekwelapheni isifo sikashukela, umuthi uSiofor uvame ukusetshenziswa.

Kufanele wazi umgomo wesenzo salo emzimbeni wesiguli nalezo zici ezingadala izinkinga.

Umkhiqizi womkhiqizo yiJalimane. Umuthi wakhelwe kwiMetformin futhi kuhloswe ukuthi unciphise ukugcwala kweglucose egazini lalabo abanesifo sikashukela.

Imininingwane ejwayelekile, ukwakheka kanye nendlela yokukhululwa

I-ejenti yithebhulethi yomlomo. Sebenzisa umuthi unqunywa kuphela ngokuyalelwa udokotela ohambelayo, kulandela imiyalo yakhe maqondana nomthamo nobuningi bokuwusebenzisa. Ngaphandle kwalokho, iSiofor ingaholela ezinkingeni.

Lesi sidakamizwa sikhona kuphela ngendlela yepilisi. Anombala omhlophe kanye nomumo obbala. Isithako esiyinhloko ekwakhekeni kwabo iMetformin.

Kumakhemisi, kunezinhlobo eziningana zeSiofor, ezihlukahluka kokuqukethwe kwento esebenzayo. Lawa amathebulethi anomthamo ka-500, 850 no-1000 mg. Iziguli zikhetha uhlobo noma olunye lomuthi olususelwa ezimfanelweni zokwelashwa kwazo.

Ngaphezu kweMetformin, ukwakhiwa kwethuluzi kuqukethe ezinye izinto ezengeziwe.

Lokhu:

• i-silicon dioxide;
• i-macrogol;
• i-povidone;
• i-magnesium stereate.

Izingxenye ezingeziwe ziqinisekisa ukubukeka okufanele kwesidakamizwa, kanye nokwandisa ukusebenza kokuvezwa.

I-Pharmacology ne-pharmacokinetics

Lesi sidakamizwa yi-hypoglycemic, evumela ukuthi isetshenziselwe ukulwa nesifo sikashukela.

Ukwehla kwezinga le-glucose ngaphansi kwethonya lakhona kutholakala ngenxa yezici ezilandelayo:

• ukunciphisa ijubane ukumunca ushukela emgodini wokugaya ukudla;
• ukuzwela kwe-insulin okungaphezulu;
• ukwehla kwezinga lokukhiqizwa koshukela esibindini;
• ukusatshalaliswa okusebenzayo kwama-carbohydrate kumaseli emisipha nokusetshenziswa.

Ngaphezu kwalokho, ngosizo lweSiofor, unganciphisa inani le-cholesterol emzimbeni, eliqinisekisa ukuvimbela kwe-atherossteosis. Imvamisa leli thuluzi lisetshenziselwa ukulahleka kwesisindo, ngoba lisiza ukunciphisa isifiso sokudla kanye nesisindo.

Ukutholwa kwengxenye esebenzayo kwenzeka emgodini wokugaya ukudla. Lokhu kwenzeka ngemuva kwamahora ayi-2,5 ngemuva kokungenzwa. Kungcono ukuthatha ngaphambi kokudla, ngoba lapho isisu sigcwele, umuthi usebenza kancane futhi kancane ngempumelelo.

I-Metformin cishe ayihlangani namaprotheni e-plasma futhi ayakhi ama-metabolites. I-Excretion yale nto yenziwa izinso. Kushiya umzimba ungashintshiwe. Half-life kudinga cishe amahora ayi-6.

Uma ukusebenza kwezinso kukhubazekile, kuzothatha isikhathi eside ukususa isakhi somuthi, yingakho iMetformin inganqwabelana emzimbeni.

Ividiyo evela kuDkt Malysheva mayelana neMetformin nokusetshenziswa kwayo kwesifo sikashukela:

Izinkomba kanye ne-contraindication

Ukucatshangelwa kwezinkomba zokusetshenziswa kubaluleke kakhulu uma usebenzisa noma yisiphi isidakamizwa. Awukwazi ukuphuza umuthi ngaphandle kwesidingo, ngoba kungaba yingozi.

ISiofor yenzelwe ukwelashwa kwesifo sikashukela sohlobo 2. Ukusetshenziswa kwayo kumphumela oyinkimbinkimbi kuvunyelwe, kepha i-monotherapy ivame ukwenziwa. Ikakhulu kaningi kunqunyelwe iziguli, ngaphezu kwesifo sikashukela, ezinezinkinga ngesisindo (ukukhuluphala ngokweqile). Umuthi usiza ukunciphisa isisindo somzimba lapho lokhu kungenakutholwa ngokudla nangokuzivocavoca umzimba.

Ukusetshenziswa kwe-Siofor ku-contraindication kwezinye iziguli.

Lokhu kusebenza kubantu abanezici ezilandelayo:

• ukungabekezelelani kwezakhi;
• Uhlobo 1 sikashukela;
• i-coma noma i-precoma ebangelwa isifo sikashukela;
• i-ketoacidosis yemvelaphi yesifo sikashukela;
• ukwehluleka ukuphefumula;
• infarction yakamuva myocardial;
• ukuba khona kokwehluleka kwesibindi;
• ukwehluleka kwezinso;
• ukuba khona kwezimila;
• ukulimala
• ukungenelela kokuhlinzwa kwakamuva noma okuhleliwe;
• izifo ezithathelwanayo ezinzima;
• i-hypoxia;
• ukunamathela ekudleni okune-calorie okuqinile;
• uphuzo oludakayo;
• ukukhulelwa
• ukondla kwemvelo;
• iminyaka yezingane.

Phambi kwanoma yisiphi salezi zimo, ukusetshenziswa komuthi kufanele kulahlwe.

Imiyalo yokusebenzisa

Ukuze ukwelashwa kulethe imiphumela ephezulu, kubalulekile ukulandela imiyalo ngokuqinile.

Udokotela kufanele atshele ukuthi ungamthatha kanjani uSiofor. Lokhu kungenxa yobuningi bezinto okufanele zibhekwe lapho ukhetha umthamo. Kunzima ukukwenza ngokwakho.

Uma kungekho izimo ezikhethekile, isidakamizwa sisetshenziswa kanjena:

1. Lapho okuqukethwe Metformin 500 mg, ingxenye yokuqala ngamathebulethi ayi-1-2. Ngaphezu kwalokho, umthamo ungandiswa. Inani elikhulu ngamathebhulethi ayi-6.
2. Lapho okuqukethwe kwento esebenzayo kungama-850 mg, qala ngeyunithi eli-1. Uma kunesidingo, khulisa leyo ngxenye. Inani elivumelekile elikhulu ngamathebhulethi ama-3.
3. Ekuqoqweni kweMetformin 1000 mg, umthamo wokuqala ukwelashwa yithebhulethi eyi-1. Ubukhulu - amaphilisi ama-3.

Uma uchwepheshe encoma ukuthatha izingcezu ezingaphezu kweyodwa ngosuku, ukwamukela kufanele kwehlukaniswe kaningana. Ukusetshenziswa kwemali kwenziwa ngomlomo kusetshenziswa amanzi ngaphandle kokugaya. Lokhu kuyasebenza ngaphambi kokudla.

Qhubeka nokwelashwa nalesi sidakamizwa njengoba kushiwo udokotela wakho. Akunakwenzeka ukwandisa le ngxenye ngaphandle kwemiyalo yakhe - okokuqala udinga ukuhlaziya amanani eglucose.

Iziguli Ezikhethekile Nezinkomba

Ukunquma izidakamizwa ezigabeni ezine zeziguli kufanele kuqaphele. Umyalo uhlinzeka ngemithetho ekhethekile kubo - kungakhathalekile ukuthi kuneminye imithetho enqunyelwe kanye nemikhawulo.

Lokhu kufaka phakathi:

1. Abesifazane abakhulelwe. Imininingwane enembile mayelana nezici zethonya leMetformin enkabeni yokukhulelwa nokukhula kwengane ayikho. Kulokhu, ukuqokwa kukaSiofor kwiziguli ezinjalo kuyagwenywa. Ekuqaleni kokwelashwa ngaleli thuluzi, kufanele kuxwayise owesifazane ukuthi kufanele azise udokotela lapho ekhulelwe.
2. Abesifazane abaqhuba ukondla kwemvelo. Ezifundweni zezilwane, kwaziwa ukuthi isithako esisebenzayo sidlulela kubisi lwebele. Amathuba okulimaza ingane akuqinisekisiwe. Kepha ukuntuleka kwemininingwane efanayo ngabantu kusiphoqa ukuthi siyeke ukusetshenziswa kwalesi sidakamizwa ngalesi sikhathi.
3. Iminyaka yezingane. Ngenxa yokuntuleka kwezifundo ezinenhloso ngezinzuzo zalo muthi, ukusetshenziswa kwawo ezinganeni ezingaphansi kweminyaka eyi-10 kuvinjelwe. Phakathi kweminyaka eyi-10 nengu-12 ubudala, ukwelashwa ngezidakamizwa kufanele kwenziwe ngaphansi kokuqashwa udokotela.
4. Abantu abadala. ISiofor ayinabungozi kwiziguli eziningi esezikhulile. Ukuqapha kudinga ukusetshenziswa kwayo ezigulini ezivame ukuphoqelelwa ukwenza umsebenzi osindayo (oneminyaka engama-60). Abantu abanjalo banengozi eyandayo ye-lactic acidosis, ngakho-ke, inkambo yokwelashwa kufanele ibhekwe uchwepheshe.

Esihlobene nezinye iziguli, ukwelashwa okujwayelekile kufanelekile.

Imiyalo ekhethekile yeSiofor ifaka izifo ezifana:

1. Ukwehluleka kwesibindi. Ngalesi sifo, senqatshelwe ukusebenzisa umuthi, ngoba isakhi sawo esisebenzayo sithinta ukusebenza kwalesi sitho.
2. Ukwehluleka kwangempela noma umsebenzi wezinso okhubazekile. Ukwembiwa kwengxenye esebenzayo kwenziwa kahle ngezinso. Njengoba unezinkinga emsebenzini wawo, le nqubo inciphisa ijubane, okuyingozi ngokuqongelela iMetformin. Kulokhu, ukungalungiseki kwezinso kuwukuphikisana nokusetshenziswa kwalo muthi.

Lesi sidakamizwa, uma sisetshenziswe kahle, asicasuli ukuthuthukiswa kwezimo ze-hypoglycemic. Ngakho-ke, lapho ulapha nokusetshenziswa kwayo, ungashayela imoto - ayithinti amandla okulawula iSiofor.

Uma ihlanganiswa nezinye izidakamizwa, kunengozi ye-hypoglycemia, engaphazamisa amandla okugxilisa ingqondo futhi yehlise ijubane lokuphendula. Lesi sici kumele sibhekwe.

Imiphumela emibi kanye ne-overdose

Ukwemukelwa kweSiofor kwesinye isikhathi kubangela imiphumela emibi.

Phakathi kwezinto ezivame kakhulu yilezi:

1. Allergy Iziveza ngendlela yokusabela kwesikhumba. Ukuvimbela ukwenzeka kwayo, ungenza isivivinyo sokuqala sokuzwela ukwakheka.
2. I-Lactic acidosis.
3. I-Anemia
4. Ukuphazamiseka emsebenzini wethimba lokugaya ukudla (ukuphefumula kobuhlungu besisu, ubuhlungu besisu, isifiso sokudla). Lezi zici zivame ukwenzeka esigabeni sokuqala sokwelashwa futhi kancane kancane aziguquki njengoba ujwayela ukuthola iMetformin.

Amathuba emiphumela emibi ancishiswe uma imiyalelo ilandelwa. Ukutholwa kwabo kudinga ukunakekelwa kwezokwelashwa.

I-overdose yesidakamizwa ayibangeli i-hypoglycemia, ebhekwa njengomphumela ongaba khona kakhulu. Uma uthatha umthamo omningi we-Siofor, i-lactic acidosis iyakhula, ekhishwa yi-hemodialysis.

Ukufana kwezidakamizwa

Isidingo sokusebenzisa ama-analogues kungenxa yezizathu ezahlukahlukene.

I-Siofor ingathathelwa indawo izidakamizwa ezifana:

• IGlucophage;
• IFommetin;
• I-Metfogamma.

Le mishanguzo ifana nomuthi okukhulunywa ngawo ngenxa yokwakheka okufanayo.

Ungase futhi ukhethe izidakamizwa ezihlobene eziqukethe enye into esebenzayo.

Udokotela kufanele akhethe umkhiqizo ozongena esikhundleni, ngoba lapho udlulisela komunye umuthi uye komunye, izinyathelo zokuphepha kufanele zibhekwe.

I-Siofor yokunciphisa isisindo - imibono yeziguli

Njengoba umuthi usiza ukunciphisa isifiso sokudla kanye nokunciphisa umzimba, abanye abantu busebenzisa ukunciphisa umzimba. Lokhu kufanele kwenziwe kuphela ngemuva kokubonisana nochwepheshe. Ukusebenza ngempumelelo kweSiofor ngezinhloso ezinjalo kungatholwa ngokuhlola ukubuyekezwa kwalabo abanciphisa isisindo.

Uqale ukuthatha uSiofor njengoba kuchazwe yi-endocrinologist. Ekuqaleni, isisindo sehlile kancane (3 kg emasontweni ama-2). Kodwa isifiso sami sokudla asizange sinciphe, kepha sakhuphuka, ngakho-ke amaphawundi aqala ukubuya. Nginovalo lokuthi esikhundleni sokunciphisa isisindo kuzoba nomphumela ophambene.

UGalina, oneminyaka engama-36

Sengithathe i-Siofor 1000 izinyanga ezi-2 manje. Ngalesi sikhathi, kuthathe isisindo esingu-18 kg. Angazi ukuthi umuthi noma ukudla kuye kwasiza yini. Ngokuvamile, ngiyaneliseka ngomphumela, bekungekho ukusabela okungekuhle, ngizizwa ngilungile.

UVera, oneminyaka engama-31 ubudala

Ngabekwa uSiofor eminyakeni engu-3 eyedlule ukuthi ngiphathe isifo sikashukela. Umuthi weza kimi, ayikho imiphumela emibi, ushukela ulawula kahle, ngakho bengilokhu ngisebenzisa sonke lesi sikhathi. Ngaphezu kweminyaka emithathu, isisindo sehlile sisuka ku-105 saya ku-89 kg. Angizisebenzisi ezinye izindlela zokunciphisa isisindo, ngilandela nje ekudleni.

ULarisa, oneminyaka engama-34

Mina ngokwami ​​ngacela udokotela ukuthi anginikeze umuthi othile ukuze nginciphise isisindo. Ezinyangeni ezintathu zokusebenzisa uSiofor, kungithathe ama-8 kg. Izinkinga ze-cycle nazo zanyamalala. Manje angiyisebenzisi, futhi isisindo sime. Ngicabanga ukuthi kufanelekile ukuphinda isifundo.

U-Irina, oneminyaka engama-29 ubudala

Ividiyo ekusetshenzisweni kweMetformin yokunciphisa isisindo:

Umuthi uthengiswa emakhemisi ngokunikezwa udokotela. Izindleko zayo ziyehluka ngokuya ngenani lezinto ezisebenzayo. Ukuthenga umuthi uSiofor 500 udinga ama-ruble angama-230-270.

Ngomthamo we-850 mg, umuthi uzodla ama-ruble angama-290-370. Izinhlobo ezahlukene zezidakamizwa iSiofor 1000 zisatshalaliswa ngentengo yama-ruble angama-380-470.