Ukuqokwa nemiyalo yokusebenzisa isidakamizwa Diabeteson MV 60 mg

Imithi yokwelapha isifo sikashukela ihlukahlukene kakhulu. Lokhu kungenxa yobukhona bokwehlukahlukana kweziguli ngazinye, ngenxa yokuthi akunakwenzeka ukudala ikhambi elikhona kuwo wonke umuntu.

Yingakho kudalwa izidakamizwa ezintsha okuhloswe ngazo ukuqeda izimpawu ze-pathological. Lokhu kufaka phakathi isidakamizwa i-Diabeteson MV.

Imininingwane ejwayelekile, ukwakheka kanye nendlela yokukhululwa

Umakhi omkhulu wezidakamizwa yiFrance. Futhi, lesi sidakamizwa senziwa eRussia. I-INN yayo (Igama Lezwe Lokungalunganga) yiGliclazide, ekhuluma ngengxenye yayo eyinhloko.

Isici somphumela waso ukwehla kwamazinga kashukela emzimbeni. Odokotela bavame ukukuncoma ezigulini ezihluleka ukunciphisa amazinga kashukela ngokuzivivinya nangokudla.

Izinzuzo zaleli thuluzi zifaka:

• ubungozi obuphansi be-hypoglycemia (lo ngumphumela wemiphumela oyinhloko wezidakamizwa ze-hypoglycemic);
• ukusebenza kahle okuphezulu;
• amathuba okuthola imiphumela lapho uthatha umuthi isikhathi esisodwa kuphela ngosuku;
• ukuthola isisindo esincane uma kuqhathaniswa nezinye izidakamizwa zohlobo olufanayo.

Ngenxa yalokhu, isifo sikashukela sisetshenziswa kabanzi ekwelapheni isifo sikashukela. Kepha lokhu akusho ukuthi kufanela wonke umuntu. Ngokuqokwa kwakhe, udokotela kufanele enze ukuhlolwa futhi aqiniseke ukuthi akukho yini ukwephulwa, ukuze ukwelashwa okunjalo kungabulali esigulini.

Ingozi yanoma yisiphi isidakamizwa ivame ukuhlotshaniswa nokungabekezeleleki kwezakhi zayo. Ngakho-ke, kubalulekile ukutadisha ukwakheka kwalo muthi ngaphambi kokuwuphuza. Isakhi esiyinhloko se-Diabeteson isakhi esibizwa nge-Glyclazide.

Ngaphezu kwalokho, izithako ezinjengalezi zifakiwe ekwakhiweni:

• i-magnesium stereate;
• maltodextrin;
• i-lactose monohydrate;
• i-hypromellose;
• i-silicon dioxide.

Abantu abathatha leli khambi akufanele babe nokuzwela kulezi zingxenye. Ngaphandle kwalokho, umuthi kufanele ushintshwe omunye.

Le khambi itholakala kuphela ngesimo samathebulethi. Mhlophe ngombala nokusaqanda ngesimo. Iyunithi ngalinye linomfanekiso oqoshwe ngegama elithi "DIA" nelithi "60".

Isenzo se-Pharmacological ne-pharmacokinetics

Lezi zibhebhe zithathwe ku-sulfonylurea. Izidakamizwa ezinjalo zivusa amaseli we-pancreatic beta, ngaleyo ndlela kusebenze ukucubungula kwe-insulin endulin.

Izici zokubonisa imiphumela yemiphumela yesifo sikashukela ifaka:

• ukukhuphuka kokuzwela kweseli ye-beta;
• ukwehla komsebenzi we-hormone echitha i-insulin;
• umphumela okhuphukayo we-insulin;
• ukukhulisa ukwanda kwezicubu ze-adipose nezicubu zomzimba esenzweni se-insulin;
• ukucindezelwa kwe-lipolysis;
• kusebenze kwe-oxidation ye-glucose;
• ukwanda kwesilinganiso sokuqhekeka kwe-glucose ngemisipha nesibindi.

Ngenxa yalezi zimpawu, i-Diabeteson inganciphisa inani le-glucose egazini leziguli ezinesifo sikashukela.

Ngokudonswa kwangaphakathi kweGlyclazide, ukuthakazelelwa kwayo ngokuphelele kwenzeka. Kungakapheli amahora ayi-6, inani layo ku-plasma likhula kancane kancane. Ngemuva kwalokho, izinga cishe lezinto ezisegazini lihlala amanye amahora ayi-6. Ukuthakazelelwa kwengxenye esebenzayo akuxhomekile ekutheni umuntu udla nini ukudla - kanye nomuthi, ngaphambi kokuthatha amaphilisi noma ngemuva kwawo. Lokhu kusho ukuthi uhlelo lokusetshenziswa kukaDiabeteson akudingeki luhlanganiswe nokudla.

Iningi elixakile le-Gliclazide engena emzimbeni lingena ekuxhumaneni namaprotheni e-plasma (cishe ama-95%). Inani elidingekayo lencwadi yezidakamizwa ligcinwa emzimbeni usuku lonke.

I-metabolism yento esebenzayo yenzeka esibindini. Ama-metabolites asebenzayo awakhiwa. I-Excretion yeGliclazide yenziwa izinso. Isikhathi sokuphila samahora ayi-12-20.

Izinkomba kanye ne-contraindication

I-Tablets Diabeteson MV, njenganoma yisiphi isidakamizwa, kufanele isetshenziswe njengokuyalelwa udokotela. Ngaphandle kwalokho, kukhona ubungozi bezinkinga.

Ukusetshenziswa okungalungile ezimweni ezinzima ikakhulukazi kungaholela ekufeni kwesiguli.

Ochwepheshe banquma lo muthi ezimweni ezilandelayo:

1. Nge-Type 2 sikashukela mellitus (uma izinguquko zemidlalo nokudla zingalethi imiphumela).
2. Zokuvimbela izinkinga. Isifo sikashukela i-mellitus singadala i-nephropathy, unhlangothi, i-retinopathy, i-myocardial infarction. Ukuthatha isifo sikashukela kunciphisa kakhulu ingozi yokuvela kwabo.

Leli thuluzi lingasetshenziswa zombili ngesimo se-monotherapy, futhi njengengxenye yokwelapha inhlanganisela. Kepha ngaphambi kokuqala ukuyisebenzisa, kufanele uqiniseke ukuthi akukho okuphikisana.

Lokhu kufaka phakathi:

• ukuba khona kokungabekezelelani komuntu ngamunye ezingxenyeni;
• i-coma noma i-precoma ebangelwa isifo sikashukela;
• uhlobo lokuqala lwesifo sikashukela;
• isifo sikashukela sikashukela;
• isikhathi sokukhulelwa nokukhulelwa;
• ukwehluleka okunzima kwezinso;
• ukwehluleka kwesibindi okunzima;
• ukungabekezelelani kwe-lactose;
• kwezingane nobusha (ukusetshenziswa kwayo akuvunyelwe kubantu abangaphansi kweminyaka engu-18).

Ngokungeziwe kokuphulwa okuqinile, izimo lapho lesi sidakamizwa singaba nomphumela ongalindelekile emzimbeni kufanele sibhekwe.

Lokhu kufaka phakathi:

• utshwala;
• ukuphazamiseka emsebenzini wenhliziyo nemithambo yegazi;
• ukungondleki noma uhlelo olungazinzile;
• ukuguga kwesiguli;
• i-hypothyroidism;
• isifo se-adrenal;
• ukuqina okuncane noma okulinganiselwe kwe-renal noma i-hepatic;
• ukwelashwa kwe-glucocorticosteroid;
• ukuntuleka kwesimo.

Kulezi zimo, ukusetshenziswa kwayo kuvunyelwe, kepha kudinga ukubhekwa kwezokwelapha ngokucophelela.

Imiyalo yokusebenzisa

I-Diabeteson yakhelwe ukulawula ushukela wegazi kuphela kwiziguli ezindala. Uthathwa ngomlomo, kuyilapho kuthuthukisa ukusebenzisa umthamo onconywe uchwepheshe isikhathi esiyi-1. Kuyinto elula kakhulu ukwenza lokhu ekuseni.

Ukudla akukuphazamisi ukusebenza komuthi, ngakho-ke kuvunyelwe ukuphuza amaphilisi ngaphambili nangesikhathi nangemva kokudla. Awudingi ukuhlafuna noma ukugaya ithebhulethi, udinga nje ukuyigeza ngamanzi.

Umthamo wesidakamizwa kufanele ukhethwe udokotela ohambelayo. Ingahluka kusuka kuma-30 kuye kwangama-120 mg. Uma kungekho zimo ezikhethekile, ukwelashwa kuqala nge-30 mg (isigamu sethebhulethi). Ngaphezu kwalokho, uma kunesidingo, umthamo ungandiswa.

Uma isiguli siphuthelwa isikhathi sokuphatha, akufanele sibambezeleke kuze kube elilandelayo ngokuphinda kabili ingxenye. Ngokuphambene nalokho, udinga ukuphuza umuthi ngokushesha lapho kuvela, nakumthamo ojwayelekile.

Iziguli Ezikhethekile Nezinkomba

Ukusetshenziswa kwe-Diabeteson MV kubandakanya ukubhaliswa kweziguli zamaqembu athile, okudingeka kuqashelwe kuwo.

Lokhu kufaka phakathi:

1. Abesifazane abakhulelwe. Umphumela we-Gliclazide ekukhulelweni nasekukhuleni kwe-fetus wafundwa ezilwaneni kuphela, futhi kulo msebenzi, imiphumela emibi ayikhonjwanga. Kodwa-ke, ukuze uqede nya ubungozi, akunconywa ukusebenzisa leli thuluzi ngesikhathi sokuzala.
2. Omama abahlengikazi. Akwaziwa ukuthi into esebenzayo yesidakamizwa idlulela obisini lwebele nokuthi iyakuthinta yini ukukhula komntwana osanda kuzalwa. Ngakho-ke, nge-lactation, isiguli kufanele sidluliselwe ekusebenziseni ezinye izidakamizwa.
3. Abantu abadala. Imiphumela emibi yesidakamizwa ezigulini ezineminyaka yobudala engama-65 ayitholakalanga. Ngakho-ke, maqondana nabo, ukusetshenziswa kwayo kumthamo ojwayelekile kuvunyelwe. Kodwa odokotela kufanele baqaphe ngokucophelela inqubekela phambili yokwelashwa.
4. Izingane nentsha. Umphumela weDiabeteson MV ezigulini ezingaphansi kweminyaka yobuningi awucwaningwanga. Ngakho-ke, akunakwenzeka ukusho ngqo ukuthi lesi sidakamizwa siyoyithinta kanjani inhlala-kahle yabo. Lokhu kusho ukuthi eminye eminye imithi kufanele isetshenziselwe ukulawula ushukela wegazi ezinganeni nakwintsha.

Kwezinye izigaba zeziguli ayikho imikhawulo.

Phakathi kokuphambana kanye nemikhawulo kulo muthi, ezinye izifo ziyashiwo. Lokhu kumele kubhekwe ukuze kungalimazi isiguli.

Ukuqapha kufanele kusetshenziswe maqondana nama-pathologies afana nalawa:

1. Ukwehluleka kwesibindi. Lesi sifo singathinta izici zesenzo sikaDiabeteson, sandisa ubungozi be-hypoglycemia. Lokhu kuyiqiniso ikakhulukazi kwifomu elinamandla lesifo. Ngakho-ke, ngokuphambuka okunjalo, ukwelashwa nge-gliclazide kuyenqatshelwe.
2. Ukwehluleka kwangempela. Ngobunzima obukhulu bokulingana balesi sifo, umuthi ungasetshenziswa, kepha kulokhu, udokotela kufanele aqaphele izinguquko enhlalakahleni yesiguli. Ngokuhluleka okukhulu kwe-renal, lo muthi kufanele ushintshwe omunye.
3. Izifo ezinomthelela ekuthuthukiseni i-hypoglycemia. Lokhu kufaka ukwephulwa emsebenzini we-adrenal gland kanye ne-pituitary gland, hypothyroidism, coronary isifo senhliziyo, kanye ne-atherosclerosis. Akuenqatshelwe ukusebenzisa i-Diabeteson ezimweni ezinjalo, kepha kwesinye isikhathi kuyadingeka ukuhlola isiguli ukuze uqiniseke ukuthi ayikho i-hypoglycemia.

Ngaphezu kwalokho, kufanele kukhunjulwe ukuthi lesi sidakamizwa singathinta ijubane lokuphendula kwengqondo. Kwezinye iziguli, ekuqaleni kokwelashwa nge-Diabeteson MV, inkumbulo kanye nekhono lokugxila kukhubazekile. Ngakho-ke, ngalesi sikhathi, imisebenzi edinga ukusetshenziswa okusebenzayo kwalezi zakhiwo kufanele igwenywe.

Imiphumela emibi kanye ne-overdose

Umuthi okukhulunywa ngawo, njengezinye izidakamizwa, ungadala imiphumela emibi.

Okusemqoka yile:

• i-hypoglycemia;
• ukusabela kwe-andrenergic;
• isicanucanu;
• ukwephulwa kwamgudu wokugaya ukudla;
• Ubuhlungu besisu
• i-urticaria;
• imivimbo yesikhumba;
• ukulunywa
• i-anemia
• ukuphazamiseka okubukwayo.

Iningi lemiphumela emibi ihamba uma uyeka ukwelashwa ngalo muthi. Kwesinye isikhathi ziyasuswa ngokwazo, njengoba umzimba uvumelana nomuthi.

Ngokweqile komuthi, isiguli sihlakulela i-hypoglycemia. Ubukhulu bezimpawu zayo kuya ngesilinganiso semithi esetshenzisiwe kanye nezimpawu zomzimba ngamunye. Kwezinye izimo, imiphumela yokweqisa ngokweqile ingabulala, ngakho-ke ungazivumelanisi nemiyalelo yezokwelashwa ngokwakho.

Ukusebenzisana kwezidakamizwa kanye nama-analog

Uma usebenzisa i-Diabeteson MV kanye nezinye izidakamizwa, kuyadingeka ukuthi unake iqiniso lokuthi ezinye izidakamizwa zingaqhakambisa umphumela wazo, kanti ezinye, ngokuhlukile, ziyenza buthaka. Izinhlanganisela ezivinjelwe, ezingafuneki nezidinga ukuqapha ngokucophelela zihlukaniswa ngokuya ngemiphumela ethile yale mithi.

Ithebula Lokusebenzelana Nezidakamizwa:

Uma usebenzisa lezi zimali, kufanele ulungise umthamo womuthi, noma usebenzise okunye.

Phakathi kwamalungiselelo we-analog weDiabeteson MV kukhona okulandelayo:

1. Okwebhizinisi. Leli thuluzi lisuselwa ku-Gliclazide.
2. I-Metformin. Isithako sayo esisebenzayo yiMetformin.
3. Phindisela emuva. Isisekelo salo muthi futhi yi-Gliclazide.

Lezi zimali zinezakhiwo ezifanayo futhi nomgomo wokudalulwa, okufana ne-Diabeteson.

Umbono wesifo sikashukela

Ukubuyekezwa komuthi i-Diabeteson MV 60 mg muhle kakhulu. Umuthi wehlisela ushukela wegazi kahle, nokho, abanye bayakubona ukuba khona kwemiphumela emibi, futhi kwesinye isikhathi baqine ngokwanele futhi isiguli kufanele sishintshele kwezinye izidakamizwa.

Ukuthatha i-Diabeteson MV kudinga ukuqaphela, ngoba ayihlanganisiwe nayo yonke izidakamizwa. Kepha lokhu akungikhathazi. Sekuyiminyaka eminingana ngilawula ushukela nalesi sidakamizwa, futhi umthamo omncane unganele.

UGeorge, oneminyaka engama-56

Ekuqaleni, ngenxa yesifo sikashukela, ngaba nezinkinga ngesisu sami - ngihlala ngihlushwa umzwelo. Udokotela weluleke ukuthi nginake izondlamzimba. Inkinga ixazululekile, manje ngijabule ngemiphumela.

ULily, oneminyaka engama-42 ubudala

UDiabetes akazange angisize. Lesi sidakamizwa sinciphisa ushukela, kepha ngangihlushwa yimiphumela emibi. Isisindo sehlile kakhulu, izinkinga zamehlo zivele, nesimo sesikhumba sishintshile. Bekumele ngibuze udokotela ukuthi asuse umuthi esikhundleni somuthi.

UNatalia, oneminyaka engama-47

Izinto zevidiyo ezibukeze umuthi i-Diabeteson kusuka kwabanye ochwepheshe:

Njengemithi eminingi esetshenziselwa ukwelapha isifo sikashukela, i-Diabeteson MV ingathengwa kuphela ngomuthi obhalwe phansi. Izindleko zalo emadolobheni ahlukene ziyahlukahluka kusuka kuma-ruble angama-280 kuya kwangama-350.