Ngenxa yokushoda okungapheli kwe-hormone ye-insulin, isifo esibi sohlelo lwe-endocrine sikhula emzimbeni - isifo sikashukela.
Ukusebenza kwabantu abanale pathology kusekelwa izidakamizwa ze-hypoglycemic ezilawula amazinga kashukela. I-Acarbose iyisidakamizwa esisebenzayo sokulwa nesifo sikashukela ekwelapheni isifo sikashukela.
Izinkomba zokuqokwa
Umuthi unqunywe yi-endocrinologist uma kukhona okulandelayo:
- Uhlobo 2 isifo sikashukela;
- okuqukethwe okweqile egazini nezicubu ze-lactic acid (i-lactic diabetesic coma).
Ngaphezu kwalokho, kuhlanganiswa nokudla kokudla, umuthi ukhonjiswa ngohlobo lwe-1 mellitus yesifo sikashukela.
Ukusetshenziswa kwomuthi akwamukeleki uma isiguli sinokuxilonga okulandelayo:
- ukungabekezelelani komuntu siqu;
- ubunzima bokuqina kwesifo sikashukela (isifo sikashukela ketoacidosis noma i-DKA);
- Ukonakala okungaphenduki kwezicubu zesibindi (i-cirrhosis);
- ukugaya okunzima futhi kubuhlungu (dyspepsia) kwesimo esingamahlalakhona;
- Izinguquko eziguqukayo ezisebenzayo zenhliziyo ezenzeka ngemuva kokudla (i-Remkheld's syndrome);
- isikhathi sokukhulelwa nokuncelisa ibele;
- ukwanda kwerhasi emathunjini;
- izifo ezingapheli zokuvuvukala zolwelwesi lwe-mucous lwe-colon (ulcerative colitis);
- ukuphuma kwezitho zesisu sangasese ngaphansi kwesikhumba (i-ventral hernia).
Ukwakheka kanye nendlela yokusebenza
I-Acarbose (igama lesiLatini elithi Acarbosum) iyi-carbohydrate epolny equkethe inani elincane loshukela olulula, olunyibilika kalula ku-ketshezi.
Umuthi uhlanganiswa ngokusebenza kwe-biochemical ngaphansi kwethonya lama-enzyme. Izinto ezingavuthiwe i-Actinoplanes utahensis.
Ama-carbohydrate e-Acarbose hydrolyzes polymeric ngokuvimbela ukusabela kwe-enzyme. Ngakho-ke, izinga lokwakhiwa namandla okufakwa ushukela emathunjini kuncishisiwe.
Lokhu kusiza ukuqinisa amazinga kashukela egazi. Umuthi awukwenzi kusebenze ukukhiqizwa kanye nokutholakala kwe-insulin yama-pancreas futhi akuvumeli ukwehla okubukhali kushukela wegazi. Imithi ejwayelekile yehlisa amathuba okuba nesifo senhliziyo, kanye nokuqhubeka kwesifo sikashukela.
Ukufakwa kwento (ukumuncwa) akuyona ngaphezu kwama-35%. Ukuqunjelwa kwento emzimbeni kwenzeka ngezigaba: ukumuncwa kokuqala kwenzeka ngaphakathi kwehora elilodwa nengxenye, okwesibili (ukumuncwa kwemikhiqizo ye-metabolic) - kubanga ukusuka emahoreni ayi-14 kuye ngosuku olulodwa.
Ngomqondo wokulimazeka okusebenzayo kokusebenza kwezinso (ukwehluleka kwezinso), ukugcwala kwento yezidakamizwa kukhuphuka amahlandla ayisihlanu, kubantu abaneminyaka engu-60 + - 1.5 izikhathi.
Umuthi uyakhishwa emzimbeni ngokusebenzisa amathumbu nohlelo lobuchama. Isikhathi sokusebenza kwale nqubo singafika emahoreni angama-10-12.
Imiyalo yokusebenzisa
Ukusetshenziswa kwe-acarbose kuhilela inkambo ende yokwelashwa. Amacwecwe kufanele adakwe okungenani ikota yehora ngaphambi kokudla.
Esikhathini sokuqala sokwelashwa, i-50 mg yomuthi inqunywa kathathu ngosuku. Uma kungekho ukusabela okungekuhle, umthamo uyandiswa ngezikhathi ezingama-2-4 ngokuphumula kwezinyanga ezi-1-2.
Umthamo owodwa omkhulu ngu-200 mg, nsuku zonke - u-600 mg.
Ngezinjongo ze-prophylactic, umuthi uthathwa ngenani elilahlekayo (50 mg) kanye ngosuku. Ngokwezinkomba, umthamo ungaphindwa kabili.
Ingabe i-Acarbose Glucobai ingasetshenziselwa ukunciphisa umzimba?
Umuthi ovame kakhulu owakhiqizwa ngesisekelo se-Acarbose yisidakamizwa saseJalimane iGlucobay. Umphumela wayo wemithi, izinkomba kanye ne-contraindication yokusetshenziswa kufana ne-Acarbose. Kodwa-ke, ukusetshenziswa kwomuthi akugcini ekwelashweni kwesifo sikashukela.
IGlyukobay idume kakhulu phakathi kwabasubathi nabantu abanenkinga yokukhuluphala ngokweqile. Lokhu kungenxa yomphumela oyinhloko wesidakamizwa - amandla okuvimba ukwakheka kanye nokumuncwa kweglucose. Imbangela yokukhulupha ngokweqile, njengomthetho, inani ngokweqile lama-carbohydrate. Ngasikhathi sinye, ama-carbohydrate angumthombo oyinhloko wemithombo yamandla yomzimba.
Lapho kuhlangana nezitho zokugaya, ama-carbohydrate alula adonswa ngokushesha ngamathumbu, ama-carbohydrate ayinkimbinkimbi adlula esiteji sokubola abe alula. Ngemuva kokuthi ukumunyiswa sekwenzekile, umzimba ufuna ukumunca izinto bese uzifaka "endaweni yokugcina". Ukuze uvimbele lezi zinqubo, labo abafuna ukunciphisa umzimba bathatha i-Glucobai njengesisebenzeli esivimba i-carbohydrate.
Izinto zevidiyo eziphathelene nezidakamizwa ezivimbela i-carbohydrate:
Ukuxhumana neminye imithi
Ngaphansi kwethonya lezidakamizwa ezahlukahlukene ezisetshenziswa ngokuhambisana ne-Acarbose, ukusebenza kwayo kungakhuphuka noma kunciphe.
Ithebula lemiphumela yokwandisa kanye nokwehla kwezidakamizwa:
Ngcono isenzo | Yehlisa isenzo |
|---|---|
izinto ezithathwa yi-sulfonylurea, okuyingxenye esemqoka yezidakamizwa ezithile ze-hypoglycemic (Glycaside, Glidiab, Diabeteson, Gliclada nabanye) | inhliziyo glycosides (digoxin nezimpawu zayo) |
amalungiselelo wokuhlobisa (i-carbon eyenziwe yasebenza, i-Enterosgel, i-Polysorb nabanye) | |
Izidakamizwa ze-thiazide diuretic (hydrochlorothiazide, indapamide, clopamide | |
ama-hormonal kanye nezindlela zokuvimbela inzalo (ngomlomo) | |
izidakamizwa ezishukumisa ukwenziwa kwe-adrenaline | |
amalungiselelo e-nicotinic acid (amavithamini B3, PP, Niacin, Nicotinamide) |
Ukusetshenziswa kwezidakamizwa okuhlangene okwehlisa umsebenzi we-Acarbose kungaholela ekwakhiweni kwezinkinga ezinkulu.
Imiphumela emibi, overdose nemiyalo ekhethekile
Imiphumela engathandeki ngesikhathi sokuphatha umuthi yenzeka ikakhulu i-epermermis kanye nepheshana esiswini.
Lokhu kufaka phakathi:
- ukuthopha;
- isihlalo sokucasuka;
- ukugaya kobuhlungu (dyspepsia);
- ubunzima bokukhuthaza okuqukethwe ipheshana lokugaya (isitho sangasese);
- izinga le-bilirubin eliphakeme (i-jaundice);
- ubomvu besikhumba okubangelwa ukwanda kwama-capillaries (erythema);
- ukungezwani okuphathelene nokungezwani komzimba.
Ukudlula umthamo obekiwe kuboniswa ngobuhlungu bamathumbu, ukwanda kwegesi, ukuhudula. Ukukhululeka kwalesi simo kuwuphawu, kanye nokufakwa ngaphandle kwezitsha ze-carbohydrate ekudleni.
I-Acarbose inqunywa ngokuqapha ngokweqile ezigulini ezinezifo ezithathelanayo, kanye nentsha engaphansi kweminyaka eyi-18.
Ngesikhathi sokwelashwa ngezidakamizwa, izimo eziphambili yilezi:
- ukunamathela ekudleni okuqinile;
- ukuqapha okuqhubekayo kwe-hemoglobin, ama-transaminases kanye noshukela (ukubalwa kwegazi).
Ekudleni, i-sucrose kufanele ithathelwe indawo ushukela.
Ukufana kwezidakamizwa
Imithi enomphumela ofanayo iqukethe i-acarbose njengento esemqoka esebenzayo.
Izidakamizwa ezimbili zisetshenziselwa ukubambela:
| igama | ifomu lokukhipha | umkhiqizi |
|---|---|---|
| I-Glucobay | Ifomu lethebhulethi engu-50 ne-100 mg | I-BAYER PHARMA, AG (Germany) |
| Alumina | Amathebulethi ayi-100 mg | "Abdi Ibrahim Ilach Sanay ve Tijaret A.Sh." (Turkey) |
Imibono yesiguli
Ukusuka kwezibuyekezo zeziguli, kungaphethwa ngokuthi i-Acarbose isebenza kahle ngokulandela ushukela wegazi ophansi, kepha ukuphatha kwayo kuvame ukuhambisana nemiphumela emibi engathandeki, ngakho-ke ukusetshenziswa kwayo akunangqondo ukwehlisa isisindo.
Umuthi wawuphathwa njengokuyalelwa ngudokotela futhi ngokuqinile ngokwemiyalo. Ngaphezu kwalokho, ngithatha i-4 mg ye-NovoNorm ngesikhathi sasemini. Ngosizo lwezidakamizwa ezimbili, kungenzeka ukugcina ushukela ojwayelekile ntambama. Ama-Acarbose "acima" umphumela wama-carbohydrate ayinkimbinkimbi, izinkomba zami amahora amabili ngemuva kokudla yi-6.5-7,5 mmol / L. Phambilini, ngaphansi kuka-9-10 mmol / L kwakungekho. Umuthi uyasebenza impela.
U-Eugene, oneminyaka engama-53
Nginesifo sikashukela sohlobo 2. Udokotela uncome uGlucobai. Amathebulethi awavumeli i-glucose ukuthi imungene emgudwini we-gastrointestinal, ngakho-ke izinga leshukela aligxili. Endabeni yami, umuthi ubujwayele ushukela ube uphawu oluphansi kakhulu lwesifo sikashukela.
U-Angelica, oneminyaka engama-36
Ngazama iGlucobai njengendlela yokunciphisa isisindo. Imiphumela emibi ehlolwe. Isifo sohudo esiqhubekayo, kanye nobuthakathaka. Uma ungahlushwa isifo sikashukela, khohlwa ngalesi sidakamizwa futhi unciphise isisindo ngosizo lokudla nokuzivocavoca umzimba.
U-Antonina, oneminyaka engama-33
Umuthi umuthi. Intengo yamathebulethi eGlucobai ingama-ruble angama-560 ngezingcezu ezingama-30, ngomthamo ongu-100 mg.
