Ukuhlanganiswa kwe-Amoxicillin ne-Clavulanic acid kuphakathi kwemithi elwa namagciwane enobubanzi besenzo. Igama lokuhweba lalo muthi yi-Amoxiclav. Lo muthi ungathathwa kuphela kwimithamo ebekwe kwimiyalo. Lokhu kuzonciphisa ingozi yokuvela okungafuneki.
Igama Lama-non-Panther Lwamazwe Ngamazwe
Umuthi we-INN - i-Amoxicillin ne-Clavulanic acid.
Ukuhlanganiswa kwe-Amoxicillin ne-Clavulanic acid kuphakathi kwemithi elwa namagciwane enobubanzi besenzo.
Atx
Lo muthi unekhodi i-J01CR02 ekuhlukaniseni i-ATX yomhlaba.
Khipha ifomu nokwakheka
Le antibiotic itholakala ngesimo samathebhulethi, amaconsi, ukumiswa kanye ne-powder. Umthamo wento esebenzayo kanye nohlu lwezinto ezisizayo kuncike kwifomu lomthamo.
Amaphilisi
Izibhebhe zine-biconvex oval ukuma. Umbala wazo umhlophe. Ezinhlangothini kukhona umbhalo we-dosage efanelekile nokuphrinta kwe- "AMC". Umuthi ukhiqizwa ngemithamo enjalo yezinto ezisebenzayo: 250 mg +125 mg, 500 mg + 125 mg no-875 mg + 125 mg. Lapho ithebhulethi inqunywa, ungabona umnyombo, oboniswe umbala ophuzi okhanyayo. Ngaphezu kwalokho, amaphilisi aqukethe i-cellulose, opadra, njll. Leli fomu lesilinganiso lifakwa emabhulashini ama-7 ama-pcs. Ama-2 blisters agcwele ebhokisini lekhadibhodi.
Amaconsi
Amaconsi esidakamizwa agcwele ezimbizeni eziyi-100 ml zengilazi emnyama. Umthamo wezithako ezisebenzayo ngu-150 mg +75 mg. Izakhi ezisizayo ezikhona emkhiqizweni zifaka amanzi alungiselelwe, okulondoloziwe, ushukela kanye nokunambitheka. Leli fomu lokukhipha lenzelwe izingane kuze kube unyaka.
Izibhebhe zine-biconvex oval ukuma. Umbala wazo umhlophe.
Powder
I-powder okuhloswe ngayo ukulungiselela isixazululo somujovo we-intravenous imhlophe noma iphuzi. Le fomu yemithamo itholakala kumithamo emi-2 yezithako ezisebenzayo eziyinhloko - 500 mg + 100 mg no-1000 mg + 200 mg. Ifakwe emabhodleleni engilazi we-10 ml.
Isiraphu
Akukhiqizwa isiraphu.
Ukumiswa
Manje kumakhemisi kukhona nokumiswa ne-powder emhlophe, okuhloswe ngayo ukuthi kulungiselelwe leli fomu lemithamo ekhaya. I-powder iqukethe i-125 mg + 31.25 mg / 5 ml yento esebenzayo. Le powder ifakwe emabhodleleni e-translucent we-150 ml.
Isenzo se-Pharmacological
Inhlanganisela ye-clavulanic acid ne-amoxicillin iyi-inhibitor esebenzayo ye-beta-lactamase. Umuthi unomphumela we-bactericidal ophikisana nama-aerobes amaningi we-gram-negative ne-gram-positive, kufaka phakathi:
- i-streptococcus pneumoniae haemophilus;
- staphylococcus aureus;
- pseudomonas aeruginosa;
- i-serratia spp;
- i-acinetobacter spp;
- umkhuhlane we-haemophilus;
- escherichia coli njll
Umuthi unomphumela obizwa ngokuthi yi-bactericidal ngokumelene nama-aerobes amaningi angamagramu.
Leli thuluzi liyasebenza ngokulwa nama-microorganisms amaningi amelana nemithi elwa nama-penicillin nama-cephalosporins. Umuthi usatshalaliswa ngokushesha kwizicubu zomzimba.
Ukuhlushwa okuphezulu kwe-metabolite esebenzayo kutholakala cishe amahora angama-1-2 ngemuva kokungenwa kanye nemizuzu engu-15 kuphela ngemuva komjovo. Ukuxhumana ngamaprotheni egazi kufinyelela kuma-22-30% kuphela. I-metabolism yezakhi ezisebenzayo zesidakamizwa iqhubeka ingxenye yesibindi. Kodwa-ke, kuze kufike ku-60% womthamo ungadedelwa ngaphandle kokuguqulwa. Ama-metabolites kanye nezakhi zomuthi ezingashintshiwe zivezwa yizinso. Le nqubo ibambezeleka amahora angama-5-6.
Izinkomba zokusetshenziswa kwe-amoxicillin ne-clavulanic acid
Lesi sidakamizwa sisetshenziswa kabanzi ekwelapheni izifo ezibangelwa ama-microorganisms azwela isenzo sawo. Imvamisa, kusetshenziselwa umuthi wokwelapha ama-pathologies wezitho ze-ENT, kufaka phakathi:
- i-tonsillitis evamile;
- i-sinusitis eyenzeka ngezindlela ezingama-acute nezingamahlalakhona;
- abezindaba ze-otitis;
- isisu se-pharyngeal;
- pharyngitis.
Ngaphezu kwalokho, i-bronchitis engapheli esigabeni se-acute, i-pneumonia ne-bronchopneumonia kungaba yinkomba yokusetshenziswa kwalo muthi. Umuthi unconyelwa i-osteomyelitis kanye nezinye izifo zamathambo. Kwezinye izimo, umuthi ubekelwe i-cholecystitis, cholangitis kanye nezinye izifo ze-biliary ipheshana.
Ukusetshenziswa kwomuthi kunesizathu ekwelapheni i-pyelonephritis, pyelitis, cystitis, i-gonorrhea, i-bacteric vaginitis, ukukhipha isisu, i-cervicitis, i-endometritis nezinye izifo ezimbalwa ezithathelanayo zohlelo lwe-genitourinary system.
Kuhlaka lokwelashwa okuyinkimbinkimbi kwezidakamizwa, ukusetshenziswa kwe-antibiotic kuvame ukuqondiswa nge-peritonitis, i-sepsis, i-meningitis ne-endocarditis. Ngaphezu kwalokho, lo muthi uvame ukusetshenziswa ekwelapheni izilonda zamagciwane esikhunjeni nezicubu ezithambile. Lo muthi usetshenziswa ekuvinjelweni kwezinkinga ezingemuva kwe-postoperative.
Contraindication
Awukho umuthi obekelwe iziguli ezinenkinga yokutheleleka nge-mononucleosis, incl. uma kunezimpawu zokuqhuma okufana nesimungumungwane. Ngaphezu kwalokho, i-phenylketonuria kanye ne-creatinine imvume engaphansi kwama-30 ml / min iyimbumbulu yokusetshenziswa komuthi. Ifomu lethebhulethi alinconywa ezinganeni ezingaphansi kweminyaka engu-12.
Contraindication ukusetshenziselwa hypersensitivity ezingxenyeni ngazinye zesidakamizwa. Ukuvinjezelwa kokusetshenziswa kwomuthi kungaba yisifo se-gastrointestinal track lesiguli.
Ungayithatha kanjani i-amooticillin ne-clavulanic acid?
Ukuqalwa komthamo wesidakamizwa kuya ngezici zenkambo yesifo, impilo ejwayelekile yesiguli nobudala bayo. Abantu abadala banikezwa umthamo ka-500 mg wesidakamizwa 1 isikhathi ngosuku. Ezinganeni, umthamo uthathwa ngokuya ngesisindo.
Ngokutheleleka kwesikhumba
Ngokutheleleka kanzima kwesikhumba, umuthi uvame ukubekwa ngendlela yemijovo. Umuthi uphathwa ngethamo lika-1 g 3 noma amahlandla amane ngosuku. Ngobunzima obukhulu bokulinganisa bokugula, ukwelashwa kungenziwa ngendlela yamathebulethi. Umthamo ungahluka kusuka kuma-250 kuya kuma-600 mg wemithi ngosuku. Ukwelapha kungathatha izinsuku eziyi-14.
Ngokutheleleka kwezitho ze-ENT
Ngokutheleleka kwezitho ze-ENT, umuthi uvame ukubekwa ngendlela yamaphilisi. Abantu abadala belulekwa ukuthi baphuze umthamo ka-500 mg kanye ngosuku ngemuva kokudla. Isikhathi sokwelashwa okungenani izinsuku eziyi-7.
Ngoshukela
Lo muthi ungasetshenziswa ekwelapheni iziguli ezinesifo sikashukela. Kubantu abadala abanalesi sifo, umuthi unqunywe kumthamo ongekho ngaphezu kwama-250 mg kathathu ngosuku. Ngesikhathi sokwelashwa, ukuqapha ngokucophelela amazinga eglucose kuyadingeka.
Ngesifo sokuphefumula
Ekwelapheni izifo zokuphefumula, umuthi ubekwa ngendlela yamaphilisi kanye nokumiswa. Umthamo wabantu abadala onconywayo ngu-250 mg izikhathi ezintathu ngosuku. Inkambo yokwelashwa izinsuku eziyi-7. Uma kunesidingo, ingakhuphuka ifike ezinsukwini eziyi-10.
Ngokutheleleka kohlelo lwezitho zofuzo
Ngezifo zohlelo lwe-genitourinary, umuthi ungabekwa ngesimo samathebulethi noma imijovo. Umthamo nesikhathi sokwelashwa kuya ngohlobo lwe-microflora ye-pathogenic eyadala inqubo yokuvuvukala.
Imiphumela emibi ye-amoxicillin ne-clavulanic acid
Ukusetshenziswa kwesidakamizwa kuhlotshaniswa nengozi yokuphendula okuningana. Imvamisa, iziguli zithola imiphumela emibi evela emgodini wokugaya ukudla, isimiso sezinzwa nesikhumba. Ukuvela kokuphendula okungahambi kahle kudinga ukwelulekwa ngudokotela kanye nokuyekiswa kokunye ngokwelashwa kwezidakamizwa.
Kusuka ohlelweni lokugaya ukudla
Imiphumela emibi ejwayelekile ehambisana nokuthatha lo muthi wokugaya ukudla ifaka i-nausea, isifo sohudo, nokuphazamiseka kwengqondo. Ukubonakala kwe-plaque emnyama olimini kanye ne-glossitis kungabonakala. Kuyaqabukela, ngesikhathi sokwelashwa ngaleli gciwane, i-enterocolitis ne-stomatitis kukhula. Ngokusebenzisa isikhathi eside umuthi, kunobungozi be-hemorrhagic colitis kanye ne-gastritis.
Ukusetshenziswa kwalo muthi kuthinta kabi isimo sesibindi. Abantu abanezinkinga ngalesi sitho bangakhulisa i-hepatitis yokudakwa kanye ne-cholestatic jaundice. Ikakhulu kaningi, le miphumela emibi kakhulu ivela ngokuhlanganiswa kwalo muthi namanye ama-antibiotic.
Kusukela ezithweni ze-hemopoietic
Ezimweni ezingavamile, ngokumelene nesizinda sokwelashwa ngalo muthi, kuvela isifo esifana nokugula kwe-serum. Mhlawumbe ukuthuthukiswa kwe-leukopenia eguqukayo ne-agranulocytosis. I-Thrombocytosis, ukwanda kwesikhathi se-prothrombin kungabhekwa.
Kusuka ohlelweni lwezinzwa
Lapho uthola ukwelashwa ngalesi sidakamizwa, kunganda ukwanda kokukhathazeka nokukhathazeka ngokwengqondo. Kube nezimo zokuqwasha nokuqwashisa ngomzimba. Ngaphezu kwalokho, ikhanda kanye nesiyezi kungenzeka. Kuyivelakancane ngesikhathi sokulashwa ngalo muthi ukuthi iziguli zinesifo esididayo futhi zidideke. Ukuphazamiseka kokuziphatha kungavela.
Ukungezwani komzimba
Ukuvela komzimba okuhambisana nokungabekezelelani ezingxenyeni ngazinye zalo muthi uvame ukubonakaliswa yi-urticaria ne-pruritus. Esikhathini esiningi, ngenkathi ngiphuza lo muthi, kuvela izimpawu zokushaqeka kwe-anaphylactic noma i-angioedema. Ukuthuthukiswa kwe-vasculitis ye-allergic akuvamile kakhulu.
Imiyalo ekhethekile
Ngaphambi kokuqala ukwelashwa ngezidakamizwa, kuyadingeka ukuthi uxoxisane nesiguli ukuze uthole imiphumela yokungezwani komzimba ngemuva kokuthatha i-penicillin. Ngaphandle kwalokho, ukusetshenziswa kwomuthi kufanele kulahlwe. Lapho kuvela ukubonakala okukhulu komzimba, ukuphathwa kwama-glucocorticosteroids kanye nokuphathwa komoya kungadingeka.
Ngokuqapha ngokweqile, umuthi kufanele usetshenziswe ezigulini ezinezimpawu zokungasebenzi kahle kwesibindi. Uma isimo siba sibi, umuthi kufanele uyekwe. Ukuqapha okukhethekile kuyadingeka futhi uma isiguli sinenkinga yokusebenza kwe-renal. Lapho usebenzisa lo muthi, kufanele neze uthole inkambo ephelele yokwelashwa, njengoba uma kungenjalo welashwa, kunengozi yokukhohlakala ngokunganaki esenzweni sokulwa namagciwane.
Ukweqisa
Ngokweqile okuqinile komthamo ophakanyisiwe wesidakamizwa, ukuphazamiseka kokulingana kwamanzi-electrolyte kanye nokuphazamiseka kwamapheshana emathunjini kungenzeka. Lapho kuvela izimpawu zokweqisa ngokweqile, kuyadingeka ukwelashwa okubonakalayo. Ezimweni ezinzima, kunqunywa i-hemodialysis.
Ukuxhumana nezinye izidakamizwa
Ukusetshenziswa kanyekanye kwama-anticoagulants kanye nalesi sakhi sokulwa namagciwane kukhulisa ingozi yokuphazamiseka kwegazi nokukhula kwegazi eliphumayo. Lokhu kusabela okungathandeki nakho kungavela ngokuhlanganiswa kwaleli gciwane le-antibacterial nokuvimbela inzalo ngomlomo. Izinhlobo ezahlukahlukene zama-diuretics, izidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala, i-Allopurinol, i-Phenylbutazone nezinye izidakamizwa ezinciphisa ukufilizwa kwe-glomerular, lapho zithathwa ndawonye kanye ne-antibiotic, kuholele ekwandeni kokuhlushwa kwe-amoxicillin.
Ukuhambisana notshwala
Le antibiotic ayikwazi ukuhlanganiswa notshwala. Lokhu kwandisa ingozi yokusabela okungekuhle.
Ama-Analog
Izidakamizwa ezinomphumela ofanayo wokwelapha zibandakanya:
- I-Augmentin.
- Arlet
- Panclave.
- I-Amoxiclav Quicktab.
- I-Lyclav.
- I-Ecoclave.
- Flemoklav.
- I-Verklav.
- I-Baktoklav.
Intengo
Izindleko zemithi elwa namagciwane emakhemisi zisukela kuma-ruble angama-45 kuye kwangama-98.
Izimo zokugcina
Umuthi osesimweni se-powder namathebulethi kufanele agcinwe endaweni eyomile emazingeni okushisa ka +25 ° C. Ukumiswa okuxutshisiwe kungagcinwa isikhathi esingaphezu kwezinsuku eziyi-7 emazingeni okushisa angadluli ku-+6 ° C.
Isikhathi sokuphelelwa yisikhathi
Ungasigcina isidakamizwa ngesimo se-powder namathebulethi weminyaka emi-2.
Umkhiqizi
Lesi sidakamizwa senziwa ngabakhiqizi bezemithi abalandelayo:
- Sandoz GmbH (Austria).
- Lek dd (ISlovenia).
- I-PJSC "Krasfarma" (Russia).
Ukubuyekezwa
Le-antibiotic kade yasebenza kwezokwelapha, yingakho ngakwazi ukuthola izibuyekezo eziningi ezivela kodokotela nasezigulini ababeyisebenzisa.
Umbono wodokotela
USvetlana, oneminyaka engama-32, uVladivostok.
Njengodokotela we-otolaryngologist, ngivame ukunquma le antibiotic kwiziguli ezinemithombo ye-otitis media. Umuthi ukuvumela ukuthi ususe ngokushesha i-microflora ye-pathogenic ebangela inqubo yokuvuvukala. Umuthi unciphisa ubungozi bezinkinga. Kubekezelelwa kahle yiziguli eziningi.
U-Irina, oneminyaka engama-43 ubudala, eMoscow
Sekuyiminyaka engaphezu kwengu-15 ngisebenza njengodokotela wezingane. Imvamisa, iziguli ezincane kufanele zinqunywe ama-antibiotic. Ukulungiswa kwe-Amoxicillin ne-Clavulanic acid bazibonakalise kahle. Ukumiswa kunambitha okuhle, ngakho-ke abazali abanabo ubunzima bokuthi le ngane ayifuni ukugwinya umuthi. Imiphumela emibi ayivelakancane uma uyiqhathanisa neminye imithi.
Iziguli
U-Igor, oneminyaka engama-22 ubudala, u-Omsk
Cishe ngonyaka owedlule wagula nge-otitis media. Umuzwa ongathandeki ezindlebeni uvimbele ukulala nokudla okujwayelekile. Umuthi olwa namagciwane wanqunyelwa udokotela. Ngazizwa ngcono ngosuku. Wawuthatha umuthi izinsuku eziyisikhombisa. Phakathi kwemiphumela emibi eye yaphawuleka ekuqwashweni kwakhe. Umphumela wokusetshenziswa kwe-antibiotic wanelisekile.
UKristina, oneminyaka engama-49, uRostov-on-Don
Iphathwe nalesi sidakamizwa i-cystitis. Ezinye izidakamizwa azange zisize. Ngemuva kwezinsuku ezimbalwa ngiphuza le-antiotic, ngazizwa sengingcono. Lesi sidakamizwa sathathwa izinsuku eziyi-14. Ukubonakaliswa kwe-cystitis kunyamalale.
U-Olga, oneminyaka engama-32, uKrasnodar
Usebenzise le antibiotic ekwelapheni i-pneumonia. Amakhambi anqunywe udokotela. Naphezu kweqiniso lokuthi lesi simo saqala ukuba ngcono ngokushesha ngemuva kokuqala kokwelashwa, eminye imiphumela emibi evela ekuyipheni yaphawulwa. Kuyo yonke inkathi yokusebenzisa lesi sidakamizwa, bengikhathazeka nge-nausea kanye nesifo sohudo. Yize kwaba nemiphumela emibi, ngawuthatha umuthi izinsuku eziyisikhombisa. I-pneumonia yelaphekile, kepha wabe esephuza ama-probiotic.
