I-Rotomox yisidakamizwa esinqunyelwe ukulwa nezifo ezithathelwanayo kanye nokuvuvukala. Inobubanzi besenzo. Kodwa-ke, izakhi ezakha ukwakheka kwazo zingaba imbangela yokuthuthukiswa kwemiphumela emibi. Umenzeli we-antimicrobial has contraindication. Ngaphambi kokuqala ukusetshenziswa, udinga ukubonana nodokotela.
Igama Lezwe elingafanele
Umuthi une-INN - Moxifloxacin.
I-Rotomox kokuba ne-INN - Moxifloxacin, imiselwe ukulwa nezifo ezithathelanayo nezivuvukelayo.
I-ATX
Ukuhlukaniswa kwamakhemikhali kwe-athomu-ukwelashwa kukhombisa ukuthi iRotomox ingeyama-ejenti antimicrobial wesenzo esisebenzayo. Ngokwekhodi ye-ATX i-J01MA14, umuthi uyisiqalo se-quinolone.
Khipha amafomu nokwakheka
Umuthi ukhiqizwa ngezindlela eziningi zemithamo. Ngayinye yayo iqukethe i-antibiotic yokwenziwa ebizwa nge- moxifloxacin. Isithako esikhulu esisebenzayo.
Amaphilisi
Amaphilisi weRotomox biconvex ayatholakala kumthamo we-400 mg. Ngakolunye uhlangothi lweyunithi ngalinye lesidakamizwa liqoshwe ngenani le-antibiotic. Umuthi ufakwa emabhulini bese ufakwa emabhokisini amakhadibhodi.
Amaconsi
Umuthi uthengiswa ngendlela yamaconsi eso. Ziyinto engabonakali ye-liquid yomthunzi okhanyayo. Amaconsi enzelwe ukusetshenziswa kwasendaweni. Kutholakala emabhodleleni akhethekile angenawo ama-nozzles ukusetshenziswa okulula.
IRotomox ithengiswa ngohlobo lwamaconsi eshiya.
Isixazululo
Isixazululo sokungenela sinombala ophuzi ophuzi. Kuthululelwa kwizilazi zeglasi ezingama-250 ml. Umthamo we-moxifloxacin kuleli hlobo lomthamo ngu-400 mg. Amabhodlela abekwe emabhokisini amakhadibhodi.
Isenzo se-Pharmacological
Umuthi uyingxenye ye-fluoroquinolone uchungechunge lwama-antibacterial agents. Umphumela we-antimicrobial womuthi ubonakaliswa ekunqobeni amandla kwethambo le-DNA yeseli le-pathogen, okuholela ekufeni kwamagciwane amaningi we-aerobic gram-positive nama-gram-negative amancane. Umphumela we-moxifloxacin udlulela kulezi zinhlobo ze-microflora ye-pathogenic njenge:
- I-Enterococcus faecalis;
- I-Staphylococcus aureus (kufaka phakathi izicubu ezibucayi ze-methicillin);
- I-Streptococcus anginosus, i-Streptococcus constellatus, i-Streptococcus pneumoniae (kufaka phakathi i-penicillin kanye ne-macrolide emelana nama-macrolide), i-Streptococcus pyogene (iqembu A);
- I-Enterobacter cloacae;
- I-Escherichia coli;
- I-Haemophilus influenzae, Haemophilus parainfluenzae;
- Klebsiella pneumoniae;
- Moraxella catarrhalis;
- I-Proteus mirabilis.
Umuthi lo unesandla ekufeni kwegciwane le-aerobic gram-positive nama-microorganisms wegram-negative.
Amanye ama-microorganisms ama-anaerobic (Bacteroides fragilis, Bacteroides thetaiotaomicron, Clostridium perfringens, Peptostreptococcus spp.), Kanye nama-ejenti asezingeni lokutheleleka ngokwesibonelo, i-Chlamydia pneumoniae, i-Mycoplasma pneumoniae, azwela emithini elwa namagciwane.
I-Pharmacokinetics
I-Moxifloxacin idonswa ngokushesha futhi ingena ku-lesion ngegazi. Ngokuphathwa ngomlomo, ukuqoqwa okuphelele kwento esebenzayo kubhekwa ngemuva kwemizuzu engaba ngu-60. I-bioavailability ephelele yesidakamizwa ingama-91%. Ngomthamo we-50-1200 mg ngethamo elilodwa noma i-600 mg / usuku lwezinsuku eziyi-10, i-pharmacokinetics ilayini, asikho isidingo sokushintsha ivolumu yomuthi ngokuya ngeminyaka nobulili.
Umuthi osebenzayo ubopha amaprotheni e-plasma ngo-40-42%.
Emathendeni, ukuqoqwa kwezakhi zamakhemikhali ezisebenzayo kuphezulu. Ukusatshalaliswa kwezakhi ze-antibiotic kuyabonakala futhi ezicutshini zendlela yokuphefumula neyokuchama, uketshezi lwebhayoloji.
Umuthi ukhishwa emzimbeni ngokusebenzisa izinso nokugaya okugaya ukudla, kungashintshiwe ngokwengxenye yama-metabolites angasebenzi. Isigamu sempilo singamahora ayi-10-12.
Umuthi ususwa emzimbeni ngokusebenzisa izinso.
Izinkomba zokusetshenziswa
I-Recept Rotomoks ebekelwe ukwelashwa okuyinkimbinkimbi kwezifo ezinzima zesikhumba nezicubu ezithambile. Isidakamizwa sisetshenziselwa ukulwa nenyumali efunyenwe ngumphakathi, inqobo nje uma ukwelashwa okujwayelekile kwama-antibiotic kusetshenziswa eminye imithi kungasebenzi. Umuthi olwa namagciwane uboniswa izilonda ezibangelwa amagciwane emgodini wokuphefumula ongaphezulu naphansi nezitho ze-ENT (i-acus sinusitis, i-bronchitis engapheli).
Contraindication
Ama-Fluoroquinolones aphikiswa ngesikhathi sokukhulelwa nangesikhathi sokuncelisa ibele. Umuthi uvunyelwe izingane ezingaphansi kweminyaka engu-18. Akunconyelwe ukuphuza umuthi wesifo sokuwa isifo sokuwa kanye nesifo sokuxineka okuvela ku-etiologies ehlukahlukene, kufaka phakathi abantu abahlushwa i-arteriosulinosis yasesikhathini noma abaye bahlaselwa imivimbo kanye nokulimala ekhanda. Ukungabekezelelani kwemithi elwa namagciwane kungukuphikisana okuqondile. Musa ukuthatha umuthi ngokungalingani kwe-electrolyte.
Ngokunakekela
Umuthi kufanele usetshenziswe ngokuqapha ku-pathologies enzima yesibindi nezinso. Iziguli ezidinga ukusetshenziswa njalo kwama-ejenti we-hypoglycemic kufanele zithole ukwelashwa kwe-fluoroquinolone ngaphansi kokuqashwa njalo kongoti ngenxa yengozi yokwehla okukhulu kwamazinga kashukela. Kubantu asebekhulile, umuthi ungadala ukuqhuma kwe-tendon.
Umuthi kufanele usetshenziswe ngokuqapha ku-pathologies yesibindi enzima.
Ungayithatha kanjani iRotomox?
Amathebulethi angathathwa, kungakhathalekile isikhathi sokudla. Kwi-sinusitis eyingozi, kunconywa ukuthatha i-400 mg ye-antibiotic kanye ngosuku. Inkambo yokwelashwa ihlala isonto. Nge-pneumonia etholwe ngumphakathi, ukwelashwa kuya ngokuhambisana nohlelo olufanayo, kepha ubude bawo buyaphindwa. Ukulwa nezilonda ezithathelwanayo ezinzima zesikhumba nezicubu ezithambile kudinga ukuthatha i-antibiotic izinsuku ezingama-21.
Uma udokotela ebeka ukuthi kudonswe umuthi umuthi, lapho imvamisa ihlanganiswa ne-0,9% isodium chloride solution noma nge-5% dextrose solution. Umthamo wesidakamizwa ngu-250 ml (400 mg) kanye ngosuku. Ukumnika kuthatha imizuzu engama-60.
Ngoshukela
Abantu abanesifo sikashukela kufanele baqaphele ngenkathi belashwa, ngoba ngokuhlangana nabaphathele i-hypoglycemic agents, ukuthatha iRotomox kungavusa ukwehla okukhulu kwamazinga kashukela egazini.
Imiphumela emibi
Umuthi ubangela imiphumela emibi ehlukahlukene eguqukayo. Ezimpawu zokuqala zokungaphenduki kahle komzimba, kuyadingeka ukuyeka ukusebenzisa lo muthi bese uthintana nodokotela.
Kwisibonakaliso sokuqala sokungaphenduki kahle kweRotomox, kufanele uthintane nodokotela wakho.
Kusuka ezicutshini zemisipha
Izinto ezisebenzayo zeRotomox ziyakwazi ukuvusa ukuthuthukiswa kwe-arthralgia, myalgia. Ebudaleni, umuthi ungadala i-Achilles tendon tendonitis.
Amapheshana wesisu
Umphumela we-moxifloxacin ohlelweni lokugaya uvame ukuhambisana nokuvela okunjengokucanuzelelwa kwenhliziyo, ukugabha, ukuhudula noma ukuqunjelwa, ukuthopha. I-Pseudomembranous enterocolitis, ukwanda komsebenzi wama-hepatic transaminases, kanye nokuthuthukiswa kwe-cholestatic jaundice akuhlanganisiwe. Iziguli zivame ukuzwa ubuhlungu besisu nomlomo owomile. Ukusetshenziswa kwe-antibiotic kuthinta kabi ukulingana kwe-microflora yamathumbu futhi kuyimbangela ye-dysbiosis.
Izitho zeHematopoietic
Ukusetshenziswa isikhathi eside kwesidakamizwa kuthinta ukusebenza kwe-hematopoiesis. Ngesikhathi sokwelashwa ngama-antibiotic, i-leukopenia, i-thrombocytopenia, i-neutropenia, ne-hemolytic anemia kuyabonakala.
Isistimu yezinzwa ephakathi
I-Moxifloxacin icasula isiyezi, i-migraine, ukuphazamiseka kokulala. Umuthi ungadala ukudangala, i-paresthesia, ukukhathazeka okukhuphukayo, ukwethuka kwemikhawulo.
Ezimweni ezingavamile, iziguli ziba nokudideka, ukwehluleka, ukuvumelanisa okungafanele kokunyakaza nokuma okunzima endaweni. Ukuvela kokulimazeka okubukwayo, ukuncipha kokuzwa kwe-acuity, ukulahlekelwa ukunambitheka, iphunga kanye nezinye izinkinga akunqatshiwe.
Kusuka ohlelweni lwezitho zofuzo
Ukuthatha iRotomox kungadala ukulimala kwezinso. Mhlawumbe ukuthuthukiswa kwe-cystitis ye-interstitial. Abesifazane bavame ukuba ne-candidiasis yangasese.
Kusuka ohlelweni lwezinhliziyo
Isakhi esisebenzayo somuthi sikhulisa isikhathi sokuphumula se-QT futhi siyimbangela ye-ventricular arrhythmia. Ngesikhathi sokwelashwa ngamakhambi, i-tachycardia ingaqhamuka, i-edema ivele, igxuma elibukhali ekucindezelweni kwegazi kanye ne-hypotension alikhishwa.
Allergies
Umuthi ubangela ukungezwani komzimba, njengokulunywa, ukuqubuka kwesikhumba, kanye okhalweni. Ukwethuka kwe-Anaphylactic kanye ne-edema kaQuincke akuvamile.
Umthelela ekhonweni lokulawula izindlela
I-Moxifloxacin ithinta kabi umsebenzi we-psychomotor. Abantu abahambisana nezimoto zokushayela noma ezinye izinto eziyinkimbinkimbi kufanele baqaphele ngesikhathi sokwelashwa kwe-quinolone.
Abantu abahambisana nokushayela kufanele baqaphele ngesikhathi sokwelashwa kweRotomox.
Imiyalo ekhethekile
Kunezimo lapho ukuthatha iRotomox kufanele kwenzeke ngaphansi kokuqashwa njalo kukadokotela. Ngokuya ngesithombe somtholampilo kanye nezifo ezihlangene, kungadingeka ukulungiswa kohlobo lwesithako somuthi. Kwezinye izimo, ukuthatha i-antibiotic akuvunyelwe ngokuphelele.
Sebenzisa ebudaleni
Abantu asebekhulile abangenawo umlando we-pathologies enzima yesibindi, izinso nenhliziyo, ukuncipha komthamo akudingeki. Kodwa-ke, izimpawu zokuqala zokuvuvukala okuhlangene, kufanele uyeke ukuphuza i-antibiotic, ngoba kunengozi yokuqhuma kwe-tendon.
Ukunquma iRotomox ezinganeni
Ezinganeni ezingaphansi kweminyaka engu-18 ubudala, umuthi uphulwe.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ngesikhathi sokukhulelwa, ukwelashwa nge-moxifloxacin akuvunyelwe, ngoba izakhi ezisebenzayo zingena kusithintelo se-placental futhi zithinte kabi ukukhula kwesibeletho. Lapho uncelisa ibele, i-antibiotic iyanqatshelwa. Uma kunesidingo sokwelashwa okubulala amagciwane kumama, ingane idluliselwa kokudla okungekhona okwenziwe emzimbeni.
Ngesikhathi sokukhulelwa, ukwelashwa ngeRotomox akuvunyelwe.
Isicelo sokusebenza kokulimala kwezinso
Uma kwenzeka umsebenzi we-renal ongasebenzi kahle, kuyadingeka ukunciphisa umthamo wansuku zonke womenzeli we-antibacterial. Ngokucaciswa okuphansi kwe-creatinine, i-400 mg yesidakamizwa ithathwa ngosuku lokuqala, khona-ke ivolumu incishiswa ibe ngu-200 mg.
Sebenzisa umsebenzi wesibindi okhubazekile
Abantu abanesibindi sokulimala kakhulu kwesibindi kufanele basebenzise umuthi ngokuqapha.
Ukweqisa
Amacala abulalayo we-Rotomox overdose awarekhodwanga. Kodwa ukwedlula ivolumu enconyiwe yesidakamizwa kungadala isicanucanu nokuhlanza, ukudideka, i-pseudomembranous enterocolitis kanye nokuquleka. Ayikho i-antidote ethile. I-Hemodialysis ayisebenzi. Emahoreni amabili okuqala ngemuva kokuthatha umthamo omkhulu we-antibiotic, kunconywa ukuhlanza isisu, uthathe namalahle ocushiwe. Ngemuva kwalokho isiguli sidinga ukwelashwa okubonakalayo.
Ukuxhumana nezinye izidakamizwa
Lapho kuhlanganiswa, iRanitidine inciphisa ukumuncwa kweRotomox. Ama-antacid, izithasiselo zokudla, amavithamini, amalungiselelo aqukethe i-iron, i-potassium, i-magnesium, i-aluminium, akha izakhi eziyinkimbinkimbi nge-antibiotic futhi anciphise ukuqina kwazo. Le mishanguzo kufanele ithathwe ngezikhathi ezithile zamahora ama-2.
Lapho kuhlanganiswa, iRanitidine inciphisa ukumuncwa kweRotomox.
Umuthi awukhuthazwa ukuthi uphathwe ndawonye nama-hypoglycemic agents ngenxa yengozi yokwehla okubukhali koshukela wegazi. I-Glucocorticosteroids ingadala ukuqhuma kwe-tendon. Ama-anticoagulants angaqondile ngokuphathwa komlomo kanyekanye okwandisa ingozi yokopha. Izidakamizwa ezingezona ezokwehlisa ukuvuvukala ezihlanganiswa neRotomox ziholela ekubambeni.
Ukuhambisana notshwala
Umuthi akufanele uphuzwe neziphuzo ezinamandla. Utshwala busehlisa ukusebenza kwe-antibiotic futhi bukhulisa imiphumela emibi.
Ama-Analog
Ama-analoggues wezidakamizwa yimithi efana neMaxiflox, i-Plevilox, iMoximac, iVigamox, i-Avelox. Le mishanguzo iqukethe i-moxifloxacin. Ungawususela lo muthi ngamanye ama-fluoroquinolones: ILevofloxacin, iNolitsin, iNorfloxacin, i-Ofloxacin. Udokotela wenza ukukhetha komuthi ngokuya ngemiphumela yokuhlolwa kwelebhu kanye nomlando wesiguli. Akunconywa ukuthi uzikhethele wena ngokwakho.
Izimo zokuphumula zeRotomox kusuka ekhemisi
Imithetho yokusabalalisa i-Rotomox evela ekhemisi ijwayelekile ekuhlinzekweni kwama-antimicrobial agents.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Umuthi uthengiswa ngumbhalo kuphela.
Intengo yeRotomox
Izindleko zomuthi zincike kwifomu lomthamo. Intengo yokupakisha amaphilisi eRussia isuka kuma-ruble angama-450-490.
Izimo zokugcina zomuthi
Amacwecwe nesisombululo sokufaka kumele agcinwe kude nemisebe yelanga eqondile kanye nezinto zokufudumeza, endaweni eyomile nengenakufinyeleleka kuyo izingane. Ukushisa kwekamelo kufanele kube sezingeni lasekamelweni.
I-Rotomox ine-anol Nolitsin, egcinwe kude nemitha yelanga kanye namadivayisi okushisa.
Isikhathi sokuphelelwa yisikhathi
Umuthi ufanele izinyanga ezingama-24 kusukela ngosuku lokukhiqizwa.
Umakhi weRotomox
Umuthi lo wenziwa ngabakwa Scan Biotech Limited (India).
Ukubuyekezwa kweziguli mayelana neRotomox
UVictoria, oneminyaka engama-35, uYuzhno-Sakhalinsk
Uphathe i-bronchitis engapheli neRotomox. Umuthi wasusa ngokushesha izimpawu zokukhuphuka, wasithatha isonto lonke. Akubanga khona nemiphumela emibi kakhulu, kepha ukuphathwa ikhanda okungapheli kwakuyinkinga.
ULarisa, oneminyaka engama-28, Magnitogorsk
Wathatha i-antibacteria ye-sinusitis eyingozi. Abanye abasasizanga. Ngemuva kwalokho kwadingeka ngiphathe i-thrush, yize ngidla kahle futhi ngigcina nokuhlanzeka. Ngeke ngifune ukubeka lezi zivivinyo empilweni yami.
Ukubuyekezwa kodokotela
Alexander Reshetov, Otolaryngologist, Tver
Ukusetshenziswa kwalo muthi olwa namagciwane kufanelekile uma umenzeli onegciwane engakhombisi ukuzwela kwezinye izidakamizwa. Kuzo zonke ezinye izimo, kuyadingeka ukukhetha umuthi onobuthi obuncane.
UValeria Mironchuk, uchwepheshe wezifo, i-Lipetsk
Imiphumela emibi ingagwenywa uma umthamo ubalwa kahle futhi izifo ezihlanganyelwe zithathelwa ingqalelo. Ebudaleni kungcono ukungazibeki ezingcupheni. Akuvamisile ukusetshenziswa ekwelapheni izifo ezithinta umchamo. Kepha kwezinye izimo, lesi sidakamizwa sibaluleke kakhulu.
