Izikhathi ezithile, iziguli zibuza ngokutholakala kwesidakamizwa esinjenge-Amoxiclav suppositories emakhemisi. Leli ikhambi elidumile lezifo ezithathelwanayo zemvelaphi ehlukahlukene. Kepha ama-suppositories ayindlela okungekho ngayo ukukhishwa kwalesi sidakamizwa.
Amafomu akhona akhishwe kanye nokwakheka
Umuthi uqukethe i-amoxicillin, okuyi-penicillin eyenziwe nge-semi eyenziwe ngezinto eziningi zemiphumela, kanye ne-clavulanic acid (i-beta-lactamase inhibitor engenakuphikwa).
Umuthi uqukethe i-amoxicillin, okuyi-penicillin eyenziwe ngesigamu futhi inethonya elikhulu lemiphumela, kanye ne-clavulanic acid.
Umuthi uyatholakala:
- Kwifomu le-powder lokwakhiwa kwezixazululo zokulimala kwe-intravenous of 500 no-1000 ml.
- Esimweni sempuphu yokwenziwa kwengxubevange yokuphathwa komlomo kwe-125, 250 ne-400 mg (kubalwa izingane).
- Amathebulethi embozwe ngefilimu ka-250, 500 no-875 mg.
Igama Lezwe elingafanele
Igama elingafanele emhlabeni jikelele yi-amoxicillin + clavulanic acid.
I-ATX
Ikhodi ye-ATX yiJ01CR02: i-amooticillin ehambisana ne-beta-lactamase inhibitor.
Isenzo se-Pharmacological
I-Clavulanic acid yakha ukuxhumana okuzinzile nezinto ezakha umuthi futhi yakha ukungatheleleki kwe-amoxicillin esenzweni se-beta-lactamases, ezikhiqizwa ngama-microorganisms. Le asidi iyafana nesakhiwo kuma-beta-lactam ama-antibiotic. Inomsebenzi omncane we-antibacterial.
I-Amoxiclav itholakala kumathebulethi amafilimu.
Umuthi unezinhlobonhlobo zemiphumela yokulwa nokutheleleka. Isebenza ngokumelene nezinto ezibucayi ezithinta i-amoxicillin, kufaka phakathi okuphuma ku-beta-lactamase, kanye ne-aerobic ne-anaerobic gram-positive ne-gram-negative bacteria.
I-Pharmacokinetics
Lezi zingxenye ezi-2 ezakha umuthi zinezimpawu ezifanayo. Inhlanganisela yabo ayiholeli ekushintsheni kwezakhiwo ze-pharmacokinetic zezakhi. Zonke izingxenye zomuthi zidonswa kahle ku-mucosa wesisu ngemuva kokulawulwa ngomlomo. Ukudla esiswini akulithinti izinga lokufakwa komuthi. Iqoqo eliphakeme kakhulu le-serum lakhiwa ihora eli-1 ngemuva kokungenisa.
I-Plasma protein binding ivela ku-17-20% i-amoxicillin ne-22-30% clavulanic acid.
Lezi zingxenye zingena kalula kwezicubu ezahlukahlukene kanye noketshezi lomzimba. Ukuhlushwa okuphezulu kakhulu kwezicubu kutholakala ihora eli-1 ngemuva kokwakhiwa kokuqongelelwa kwe-serum. Zombili izakhi zomuthi zingena kalula kwi-placenta. Ekugxilweni okuphansi, adlulela ubisi lwebele.
I-Amoxicillin ishiya umzimba nomchamo ngendlela efanayo eyamukelwa ngayo. I-Clavulanic acid ibhekana nenqubo ye-metabolic, bese ishiya nomchamo, indle kanye ne-carbon dioxide eqediwe.
Izinkomba zokusebenzisa i-Amoxiclav
Umuthi usetshenziselwa ukutheleleka okucasulwa yizicubu ezingamagciwane ezithinta izakhi zomuthi:
- Izifo zepheshana lokuphefumula eliphezulu nezitho ezihambisana nazo (izinhlobo ezahlukahlukene ze-sinusitis, i-otitis media kanye ne-tonsillitis).
- Izilonda ezithathelwanayo zomgudu wokuphefumula ophansi (i-bronchitis engapheli, i-bronchopneumonia, i-lobar pneumonia).
- Izifo ze-urinary tract (urethritis, pyelonephritis, cystitis).
- Izifo ze-gynecological.
- Izilonda zesikhumba nezinye izicubu, kufaka phakathi ukulunywa yizilwane.
- Ukugula kwamathambo namalunga, njenge-osteomyelitis.
- Ukutheleleka okutheleleka kwe-tumbo esiswini kanye nephephabhuku i-biliary (cholecystitis).
- Izifo zangasese (i-chancre emnene, i-gonorrhea).
- Ukuvimbela izifo ezithathelwanayo ngemuva kokuhlinzwa.
Contraindication
I-Amoxiclav icutshaniswe nezimpawu ezilandelayo:
- Ukuba khona kwe-hypersensitivity kuzakhi zomuthi.
- I-Hypersensitivity, kufaka phakathi ukusabela kwe-anaphylactic.
- Ukuphazamiseka kwesibindi, okubangelwa ukusetshenziswa kwalesi sidakamizwa.
- Ngezifo zamapheshana emathunjini, ukwephulwa okukhulu kwezinso, isibindi, i-pseudomembranous colitis, umuthi kufanele uthathwe kuphela ngokuyalelwa ngudokotela.
Ungayithatha kanjani i-Amoxiclav
Ezigulini ezinezimpawu ezibucayi, ithebhulethi e-1 ikhonjiswa inesisindo esingu-250 + 125 mg izikhathi ezi-3 ngosuku noma i-1 ithebhulethi 500 + 125 mg izikhathi ezi-2 ngosuku. Ezimweni ezinkudlwana zezifundo, amaphilisi ama-3 ama-500 + 125 mg ngosuku noma amaphilisi ama-2 ama-875 + 125 mg ngosuku akhonjisiwe.
Ithuluzi liyadliwa kungakhathalekile ukuthi kudliwe. Kodwa akunconywa ukuba uyithathe ngaphambi kokudla ukuze ugweme ukusabela okungekuhle kwephephisi lesisu.
Kunezinhlobo ezi-2 zomthamo we-powder wokulungiselela ukumiswa:
- I-125 mg ye-amoxicillin ne-31,5 mg ye-clavulanic acid ku-5 ml wento esebenzayo.
- 250 mg no-62,5 mg ku-5 ml, ngokulandelana.
Leli khambi kumele lichithwe ngezikhathi ezinjalo:
- Lapho uthatha amaphilisi ama-3 ngosuku, isikhawu samahora ayisishiyagalombili kufanele sibhekwe phakathi kwawo.
- Lapho usebenzisa amaphilisi ama-2 - amahora ayi-12.
Ngenxa yalokhu, umzimba uzogcina ukugcotshwa okuphezulu komuthi, futhi umphumela wawo uzoqina.
Inkambo yokwelashwa ihlala kusuka ezinsukwini ezi-5 kuye emasontweni amabili.
Ngaphambi noma ngemuva kokudla
Ithuluzi liyadliwa kungakhathalekile ukuthi kudliwe. Kodwa akunconywa ukuba uyithathe ngaphambi kokudla ukuze ugweme ukusabela okungekuhle kwephephisi lesisu.
Ukuthatha umuthi wesifo sikashukela
Kulesi sifo esibucayi, ukusetshenziswa kwalesi sidakamizwa kufanelekile. Uthathwa njengokuyalelwe ngudokotela. Ithuluzi alithinti amazinga kashukela egazini. Esikhathini sikashukela, ukwelashwa kungaba yinde.
Esikhathini sikashukela, ukwelashwa kungaba yinde.
Lapho kukhona isifo esinjalo ebudaleni, kubalulekile ukuthatha umuthi ngokuqapha. Umthamo onconywayo yi-312,5 mg izikhathi ezi-2 ngosuku. Isifundo sithatha izinsuku ezingama-5- 10. Ngesikhathi sokuphuza umuthi, inani elikhulu lamanzi kufanele lichithwe ukuqeda umzimba we-pathogenic microflora.
Imiphumela emibi ye-Amoxiclav
Ukusabela okuhlukile akuvamile ukwenzeka. Bangaziveza ngezindlela ezahlukahlukene futhi bathinte izitho nezinhlelo ezahlukahlukene. Izifo ezifana ne-candidiasis, i-hepatitis, i-jaundice zingakhula (lezo zokugcina zivame ukwenzeka kubantu abadala abathola ukwelashwa isikhathi eside).
Amapheshana wesisu
Njengamanye ama-antibiotic, leli thuluzi libulala womabili amagciwane angama-pathogenic nalawo azuzisayo. Kungadala ukwephulwa kwe-microflora (dysbiosis) yamathumbu, okuhambisana nesifo sohudo, isicanucanu, izinhlungu esiswini. Kwezinye izimo, i-pseudomembranous colitis ingaqala ukukhula.
Izitho zeHematopoietic
Izinguquko ze-pathological ekwakhiweni kwegazi zingavela. Lokhu kungaholela ezifweni ezifana ne-leukopenia, anemia, neutropenia, thrombocytopenia, agranulocytosis.
Isistimu yezinzwa ephakathi
Imiphumela emibi evela ohlelweni lwezinzwa eliphakathi nendawo ingahle ivele: isiyezi, i-migraine, ukuphazamiseka kokulala.
Imiphumela emibi njengokuphazamiseka kokulala kungenzeka engxenyeni yesistimu yezinzwa ephakathi.
Kusuka ohlelweni lomchamo
Ushintsho ekwakhekeni komchamo kungenzeka: ukubonakala kokufakwa kwegazi, i-crystalluria.
Kusuka ohlelweni lwezinhliziyo
Azikho izinto ezingahambi kahle ohlelweni lwezinhliziyo ezitholakele.
Allergies
Ukuvela kwe-allergic kungenzeka ngendlela yokuqhuma kwesikhumba, i-dermatitis, i-urticaria (ezimweni ezingavamile, ukushaqeka kwe-anaphylactic, i-edema kaQuincke, i-necrolysis enobuthi).
Ukungezwani komzimba kungavela njengokuqhuma kwesikhumba.
Imiyalo ekhethekile
Kwenqatshelwe ukuphuza utshwala ngenkathi uthatha lo muthi olwa namagciwane. Lokhu kungadala ukungasebenzi kahle kwesibindi neminye imiphumela emibi.
Ungazinikeza kanjani izingane
Ezinganeni, umthamo ubalwa ngokuya ngesisindo. Inketho enhle ukusebenzisa ukumiswa. Ubunzima besifo esincane nesilinganiselwe, umthamo onconywayo ngu-20 mg nge-1 kg yesisindo sengane; ezimweni ezinzima, i-40 mg / kg. Umyalo unamathiselwe kulo muthi, ngenxa yokuthi ungabala ukubalwa komthamo wengane.
Izingane ezingaphezulu kweminyaka engu-12 ubudala ezinesisindo esingaphezu kwama-40 kg kufanele zisebenzise umthamo ofanayo womuthi njengabantu abadala.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ngesikhathi sokukhulelwa nangesikhathi sokuncelisa, umuthi kufanele uphathwe ngokucophelela futhi uqondiswe kuphela ngudokotela.
Ukweqisa
Ukweqa ngokweqile kungaholela ekuphazamisweni kwephephisi lesisu, izinso, isibindi nezinye izitho nezinhlelo. Kwakungekho ukufa. Uma umthamo odingekayo udluliwe, thintana nodokotela. Usizo lwezokwelapha luqukethe ukulinganisa ibhalansi yama-electrolyte emzimbeni. Izinto ezisebenza ngokweqile zisuswa emzimbeni nge-hemodialysis.
Uma umthamo odingekayo udluliwe, thintana nodokotela.
Ukuxhumana nezinye izidakamizwa
Ithuluzi alinconywa ukuthi lisetshenziswe ngasikhathi sinye nezinye izidakamizwa nama-antibhayoriki, ngoba ubudlelwane obunjalo bungadala ukusabela okungalindeleki komzimba. Lesi sidakamizwa asihambisani nezinto eziningi ezisebenzayo nemithi, phakathi kwako oku:
- ama-antacid;
- i-glucosamine;
- ama-laxatives;
- aminoglycosides;
- ascorbic acid;
- okokugcobisa;
- i-allopurinol;
- phenylbutazone;
- methotrexate;
- i-allopurinol;
- disulfiram;
- ama-anticoagulants;
- i-rifampicin;
- ama-bacteriostatic antibiotics (ama-macrolides, ama-tetracyclines);
- ama-sulfonamides;
- i-probenecid;
- izindlela zokuvimbela inzalo ngomlomo.
Ama-Analog
Kumalungiselelo afanayo aqukethe into efanayo esebenzayo, faka:
- I-Amovicomb.
- I-Amoxiclav Quicktab.
- Arlet
- I-Augmentin.
- I-Baktoklav.
- I-Verklav.
- I-Clamosar.
- I-Lyclav.
- I-Medoclav.
- Panclave.
- Isikhundla.
- I-Rapiclav.
- Taromentin.
- Flemoklav Solyutab.
- I-Ecoclave.
Umuthi ungashintshwa ngu-Arlet.
Imibandela yekhefu lekhemisi
Shiya ngokuya ngomuthi.
Ngingakwazi ukuthenga ngaphandle kadokotela
Umuthi usatshalaliswa kuphela ngomuthi obhaliwe.
Izindleko
Intengo yesidakamizwa ngesimo sokumiswa emabhodleleni isuka kuma-ruble ayi-117. Izindleko zamathebhulethi (ama-pcs angama-20. Kwipakethe, i-Quicktab) - kusuka kuma-ruble angama-358, u-powder wokulungiswa kwesisombululo sokuphathwa kwe-intravenous - ruble ezingama-833.
Izimo zokugcina zomuthi
Gcina umuthi endaweni emnyama futhi ungafinyeleleki kuwo wezingane emazingeni okushisa angeqi ku-25 ° C.
Isikhathi sokuphelelwa yisikhathi
Impilo yeshelf iyiminyaka emi-2. Kuyenqatshelwa ukusebenzisa ngemuva kokuphela kwalesi sikhathi.
Umkhiqizi
Umuthi ukhiqizwa emazweni ama-2: iSlovenia (Lek D.D.) nase-Austria (Sandoz).
Ukubuyekezwa kodokotela neziguli
UTatyana, oneminyaka engama-32, uKrasnodar
Le antibiotic isize ukwelapha kalula i-sinusitis ezigulini eziningi. Ngikweluleka ukuthi uthathe i-Biolact Forte ngokuhambisana ne-probiotic ukuze ungaphazamisi i-microflora yamathumbu.
UMargarita, oneminyaka engama-45, uNizhny Novgorod
Banikeze ingane umkhuhlane njengoba kubekwe udokotela. Isizwe ngokushesha, ayibanga nemiphumela emibi. Ngigculisekile. Kuyinto elula ukuthi umuthi utholakala ngesimo sokumiswa, unambitha okuhle, futhi ingane uyiphuza ngaphandle kwezinkinga.
U-Alexander, oneminyaka engama-46, uVolgograd
Ngibekela iziguli leli khambi lokwelashwa kwe-prostatitis kuhlangene ne-Smartprost. Okungabizi, umphumela osheshayo. Ayikho imiphumela emibi eye yaphawulwa.
UMikhail, oneminyaka engama-28, u-Ufa
Indlebe yami yayibuhlungu kakhulu, ngaya kudokotela. Kutholwe ngemidiya ye-otitis. Udokotela usinikeze lo muthi. Ubuhlungu baqala ukudlula ngokushesha, kepha kwavela isiyezi. Udokotela wathi umphumela omubi onjalo uvamile. Leli ithuluzi elinamandla, ukwamukela kwalo kumele kuhlanganiswe nokusetshenziswa kwama-probiotic (Linex).
