Ukuze wehlise izinga lokuhlushwa futhi ulawule izinkomba ze-lipids, cholesterol ne-triglycerides egazini, nikeza izidakamizwa ezingokwesigaba sama-statins. Isibonelo esicacile yi-Atoris ne-Atorvastatin. Zombili lezi zidakamizwa zinento efanayo esebenzayo, ukukhishwa kwethebulethi. Umphumela wabo wokwelapha uyefana. Umehluko kuphela izinkampani zezidakamizwa kanye namanani.
Udokotela ohambelayo kuphela onganquma ukuthi yisiphi isidakamizwa esincono futhi esisebenza kahle esigulini - i-Atoris noma i-Atorvastatin.
Isimilo se-Atoris
Ifomu lokukhishwa kwe-Atoris - amaphilisi ahlanganiswe ngefilimu. Isithako esikhulu esisebenzayo yi-atorvastatin. I-capsule eyodwa iqukethe i-10, 20, 30, 40, 60 no-80 mg yale nto. Ukupakisha kufaka izingcezu eziyi-10, 30, 60 no-90.
I-Atoris ne-Atorvastatin zithathwa ukwehlisa izinga lokuhlushwa nokulawula i-lipid, cholesterol ne-triglycerides.
Umuthi uvimbela ukukhiqizwa kwe-cholesterol ngenxa yokwakheka kwe-enzyme ekwehlisa ukuqina kwayo kuyi-plasma yegazi. Izinga lama-lipoprotein ayingozi emzimbeni liyancipha ngenxa yethonya lezinto ezisebenzayo kuma-LDL receptors. Kulokhu, ngokuphambene nalokho, kukhona ukwanda kokuxineka kwamazinga aphezulu we-lipoproteins (HDL), okuvuselela umphumela we-anti-atherosranceotic. Umuthi usiza ukunciphisa inani lamakhompiyutha adala indawo ebekelwa amafutha.
Izinkomba ezisetshenziswayo:
- i-hyperlipidemia eyinhloko;
- hypercholesterolemia;
- i-hypertriglyceridemia;
- ukuvimbela izifo zenhliziyo nemithambo yegazi, ikakhulukazi kubantu abasengozini (kusukela eminyakeni engama-55 ubudala, ukuba khona kwesifo sikashukela, umfutho wegazi ophakeme, imikhuba yokubhema, ukubekeka phambili kofuzo);
- ukuvimbela izinkinga ze-pathologies zenhliziyo nemithambo yegazi, kufaka phakathi i-stroke, isifo senhliziyo, i-angina pectoris nabanye.
Amacwecwe enzelwe ukusetshenziswa ngaphambi kokudla noma ngemuva. Okokuqala, i-10 mg ibekiwe, kepha khona-ke umthamo ungakhuphukela ku-80 mg. Kuya ngokusebenza kokwelashwa. Izinguquko ezinhle ziyabonakala ngemuva kwamasonto ama-2 wokusebenzisa umuthi ngendlela ehlelekile.
I-Atoris ivimbela ukukhiqizwa kwe-cholesterol ngenxa yokwakheka kwe-enzyme enciphisa ukugxila kwayo kuyi-plasma yegazi.
Contraindication ukusetshenziselwa:
- i-pathology yemisipha;
- ukuqina kwesibindi;
- ukwehluleka kwesibindi okunzima;
- isifo sesibindi esiteji esibuhlungu (ikakhulukazi i-hepatitis of etiologies ehlukahlukene);
- ukushoda kwe-lactase, ukungabekezelelani kwe-lactose;
- kukhulisa ukuthambekela komuntu ngamunye kulo muthi nezakhi zawo.
Ezinganeni ezingaphansi kweminyaka eyi-18, kanye nabesifazane ngesikhathi sokukhulelwa nokuncelisa, umkhiqizo awulungele. Ngokuqapha, kufanele kuthathwe uma kwenzeka ukuphuza ngokweqile okungapheli, ukungalingani okukhulu kwe-electrolyte, i-pathologies yesistimu ye-endocrine kanye ne-metabolism, izifo ezinzima ezithathelwanayo, isithuthwane, hypotension.
Isici se-Atorvastatin
Uhlobo lomuthi ngamathebulethi ngefilimu emhlophe. Isithako esiyisisekelo esisebenzayo yisihlanganisi segama elifanayo. Ithebhulethi eyi-1 iqukethe u-10 no-20 mg. Ngaphezu kwalokho, kunezakhi ezisizayo.
I-Atorvastatin inethonya lokukhetha. Iyanciphisa ukugcwala okwandisiwe kwe-cholesterol embi egazini. Lokhu kungenxa yokuthi inani lama-membranes akhethekile weseli aqaphela i-LDL liyanda. Zibhujisiwe, futhi ukwakheka kwazo esibindini kuvinjelwe kamuva. Kulokhu, ukuqoqwa kwe-HDL kukhula kancane kancane.
I-Atorvastatin inciphisa ukugcwala okwandisiwe kwe-cholesterol embi egazini.
I-Atorvastatin ichazwa kulezo zimo njenge-Atoris, ukuze isetshenziswe kanyekanye nokudla okufanele okunempilo kanye nezinye izindlela ezingezona izidakamizwa. Okokuqala, inani lemihla ngemihla lele ngxenye liyi-10 mg, kodwa-ke lingandiswa ngo-80 mg.
Contraindication ifaka ukwehluleka kwesibindi, ezinye izinkinga zesibindi, kanye nokungabekezelelani kabi kwezidakamizwa nezakhi zalo. I-Atorvastatin ayivunyelwe izingane ezingaphansi kweminyaka engu-18 ubudala, abesifazane ngesikhathi sokukhulelwa nokuncelisa.
Ukuqhathanisa kwe-Atoris ne-Atorvastatin
Ukunquma ukuthi yisiphi isidakamizwa esingcono - i-Atoris noma i-Atorvastatin, udinga ukuziqhathanisa, ukunquma ukufana nokwehluka.
Okujwayelekile
I-Atorvastatin iyisithako esiyinhloko esisebenzayo kuzo zombili lezi zidakamizwa, ngakho-ke umphumela wamakhemikhali uyafana. Kuqukethe okulandelayo:
- ukwehla kwe-cholesterol yegazi;
- ukwehla kokuxineka kwama-lipoprotein egazini;
- ukuvimbela ukukhula ngokweqile kwezakhiwo zamaselula ezindongeni zemithambo yegazi;
- ukunwetshwa kwe-lumen yemithambo yegazi;
- Ukwehla kokubonakala kwegazi, ukucindezelwa kwesenzo sezinto ezithile ezibhekene nokuqina kwaso;
- ukwehla kwamathuba okukhula kwezinkinga ezihambisana nesifo se-coronary.
Ngokunikwa lo mphumela we-pharmacological, womabili ama-statin anqunyelwe abantu asebekhulile noma asebekhulile, futhi okuvame kakhulu kubantu abasha. Izinkomba ezisetshenziswe e-Atoris nase-Atorvastatin zicishe zifane. Imithi inconywa ngezinhloso zombili zokwelapha neze-prophylactic.
Isici sawo womabili ama-statins isikhathi sokusetshenziswa kwawo. Esikhathini sokuqala, udokotela unquma umthamo omncane, kodwa-ke ungangezelelwa ukulawula i-cholesterol yegazi. Isifundo sizoba isikhathi eside, futhi kwesinye isikhathi izidakamizwa ziyadingeka ukuze zisetshenziswe impilo yonke. Kulesi simo, ukuhlaziywa kwebhubhoratri kwamapharamitha egazi kwenziwa ngezikhathi ezithile.
Ukuthuthukiswa kwemiphumela emibi e-Atoris nase-Atorvastatin kuyafana futhi ngenxa yesakhi esisebenzayo esifanayo. Lokhu kufaka phakathi imiphumela yezidakamizwa ku:
- uhlelo lwezinzwa - ikhanda, i-asthenia, izinkinga zokulala, ukuqaqamba, ukuqina kwemilenze, izinkinga zememori;
- uhlelo lwenhliziyo - ukwehlisa noma ukukhulisa umfutho wegazi, ukukhuphuka kwenhliziyo;
- uhlelo lokugaya ukudla - ukubukeka kobuhlungu obungachazwanga esiswini nangaphansi kwezimbambo ngakwesokunene, ukushisa kwenhliziyo, isicanucanu, ukuhlanza, ukubopha, ukwanda kwegesi, ukushintshana kwezisu nokuqunjelwa, ngesinye isikhathi i-hepatitis, cholecystitis, pancreatitis, ukwehluleka kwesibindi;
- amasistimu wokuchama nokuzala - ukuhluleka kwezinso, ukwehla kwe-potency, i-libido;
- uhlelo lwe-musculoskeletal - Ubuhlungu emalungeni, emisipha, emathanjeni, emgogodleni;
- uhlelo lwe-hematopoietic - thrombocytopenia (ngesinye isikhathi);
- isikhumba - ukuqubuka, ukulunywa, ukwehluka ngenxa yokusabela komzimba;
- izitho zomqondo - ukuphazamiseka kwendawo yokuhlala, izinkinga zokuzwa.
Uma imiphumela engathandeki ivela ngenxa yokuthatha i-Atoris noma i-Atorvastatin, khona-ke kuyadingeka ukumisa ukusetshenziswa kwezidakamizwa uye esibhedlela. Izincomo zoDokotela yilezi: ukuncishiswa komthamo, ukufaka esikhundleni nge-analog noma ukuqedwa ngokuphelele kwama-statins.
Umehluko phakathi kwe-Atoris ne-Atorvastatin ukugcotshwa kwento esebenzayo esebenzayo.
Uyini umehluko
Umehluko phakathi kwe-Atoris ne-Atorvastatin ukugcotshwa kwento esebenzayo esebenzayo. Owokuqala une-assortment ebanzi - 10, 20, 30, 40, 60 no-80 mg, kanti umuthi wesibili une-10 no-20 mg kuphela. Lapho ulungisa umthamo, i-Atoris izoba lula ngokwengeziwe.
Umehluko wesibili umenzi. I-Atorvastatin ikhiqizwa yiBiocom, Vertex, Alsi Pharma, okungukuthi, izinkampani zaseRussia. I-Atoris ikhiqizwa nguKrka eSlovenia.
Yikuphi okushibhile
I-Atoris ingathengwa eRussia kuma-ruble angama-400-600 ngephakethe ngalinye ngamathebulethi angama-30 aqukethe u-10 mg wengxenye esemqoka. Uma ukhetha inani elifanayo lamaphilisi, kepha nge-20 mg, khona-ke izindleko zizofika kuma-ruble ayi-1000.
I-Atorvastatin-teva eRussia ithengiswa cishe ama-ruble ayi-150 ngephakethe ngalinye elinamaphilisi ayi-10 mg.
Yini engcono i-Atoris noma i-Atorvastatin
Izidakamizwa zinezinga elifanayo lobufakazi. Yomibili le mikhiqizo ayithathwa njengeyangempela. Lawa angamakhophi akhiqizwe kabusha omuthi weLiprimar, ngakho-ke i-Atorvastatin ne-Atoris zombili zenziwe ngogesi futhi zisesimweni esifanayo.
Kepha odokotela abaningi neziguli bayaqiniseka ukuthi izidakamizwa zakwamanye amazwe zingcono kunalezi ezifuywayo, ngakho-ke bakhetha i-Atoris. Ngokuqondene nentengo, i-Atorvastatin izoba eshibhile kakhulu. Kepha udokotela uzowukhetha umuthi.
Ukubuyekezwa kweziguli
U-Elena, oneminyaka engama-25, eMoscow: "Ugogo wami unesifo sokuqina kwemithambo yegazi emgodini, i-cholesterol ephezulu, i-LDL. Unqunywe u-Atoris. Iphrofayili yokugcina ye-lipid ikhombise ukwehla kwe-cholesterol ne-LDL, ukwanda kwe-HDL, ngakho-ke umuthi uyasebenza."
U-Ana, oneminyaka engama-42, uKaluga: "I-Atorvastatin ingumuthi ojwayelekile. Ngingakwazi ukukubekezelela kahle, imiphumela emisha ibingakabonakali. I-Cholesterol, umahlulelwa yilokhu kuhlaziya, incipha kancane kancane."
Odokotela babuyekeza nge-Atoris ne-Atorvastatin
U-Andrei, oneminyaka engama-38, udokotela wezifo zemizwa: "Ngaphandle kwesimo sezezimali seziguli, ngiphikelela ukuthi ngithathe i-Atoris. Umuthi uyasebenza, usezingeni eliphezulu futhi uyafakazelwa. Imiphumela emibi ayiveli."
U-Irina, oneminyaka engu-30, udokotela ohlinzayo: "I-Atorvastatin iyinhlangano eshibhile kodwa esebenza ngempumelelo yezidakamizwa zakwamanye amazwe. Inhlanganisela enhle yamanani nekhwalithi. Iyatholakala kuzo zonke iziguli. Iyasiza nge-hyperlipidemia."