I-Dianormet umuthi olwa nesifo sikashukela wehlisa ushukela wegazi. Kusetshenziswa ekwelapheni isifo sikashukela esinga-insulin futhi asikukhuthazi ukwenziwa kwehomoni.
Igama Lezwe elingafanele
I-Metformin (Metformin).
I-Dianormet umuthi olwa nesifo sikashukela wehlisa ushukela wegazi.
I-ATX
A10BA02.
Khipha amafomu nokwakheka
Uhlobo lomthamo we-Dianormet ngamathebulethi. Zitholakala ezinhlotsheni ezi-2: 500 no-850 mg wento esebenzayo, eyi-metformin hydrochloride. Ngaphezu kwalokho, ukulungiswa kufaka isiraphu yesitashi, i-talc ne-magnesium stearate.
Amacwecwe asetshenziselwa ukusetshenziswa komlomo. Kugcwele emabhulini izingcezu eziyi-15 noma emabhodleleni epulasitiki wezingcezu ezingama-30. Womabili amabhulokhi namabhodlela afakwe emaphaketheni amakhadibhodi.
Uhlobo lomthamo we-Dianormet ngamathebulethi.
Isenzo se-Pharmacological
Into esebenzayo ye-Dianormet inamandla okucindezela ukwakheka kwe-glucose egazini, amahhala wamafutha acid namafutha. Umuthi uvuselela ukumuncwa kweglucose ngamaseli emisipha.
I-Metformin ithuthukisa ukuhamba kwegazi esibindini, ngenxa yokuthi ushukela uphenduka ngokushesha ube yi-glycogen.
I-Pharmacokinetics
Into esebenzayo isuthwa emgudwini wokugaya ukudla. Cishe amahora angama-2-2,5 ngemuva kokuthatha iphilisi, i-metformin ifinyelela ekuqineni kwe-plasma enkulu, futhi ukwehla kwalesi paramitha kuqala ngemuva kokuphela kokufakwa. Lokhu kwenzeka ngemuva kwamahora ayisithupha.
Isigamu sempilo singamahora 1.5-5,5. Igcotshwa yizinso, kepha ngezifo zalesi sitho esibhanqiwe, ukubonwa kwesidakamizwa kuyabonakala.
Izinkomba zokusetshenziswa
Umuthi usetshenziswa ekwelapheni uhlobo lwesifo sikashukela sohlobo 2 (lolu uhlobo lwesifo lapho i-insulin inganikezwa khona). Umuthi ikakhulukazi usiza labo abanesifo sikashukela abakhuluphele futhi abakwazi ukubhekana naso ngokudla nangokuzivocavoca.
Iziguli ezikhuluphele ezinesifo sikashukela sohlobo 1 zibuye zinconywe ukuthatha i-Dianormet. Kepha umuthi ubekiwe njengendlela eyengeziwe yokwelashwa kwe-insulin ukuze wehlise isidingo se-insulin.
Contraindication
Umuthi uphambaniswe neziguli ezinokuzwela okwengeziwe kwento esebenzayo nezinye izinto ezakha i-Dianormet.
Akunconyelwe ukuphuza umuthi phambi kwalezi zimo ezilandelayo zokugula:
- i-coma, i-precoma, i-ketoacidosis ehambisana nokuthuthukiswa kwesifo sikashukela esigulini;
- i-renal hypoxia kanye nezinye izifo ezisezinso;
- ukubonakaliswa kwezifo ezahlukahlukene ezenzeka ngendlela eyingozi noma engapheli ehlobene nokuthuthukiswa kwezicubu hypoxia, kufaka phakathi ukwehluleka kokujikeleza;
- ukwehluleka kwesibindi;
- i-metabolic noma i-lactic acidosis;
- uphuzo oludakayo.
Kufanele wenqabe ukuthatha i-Dianormet lapho wenza ucwaningo lwezokwelapha olwenziwa kusetshenziswa imisakazo noma izinto eziqukethe iodine.
Akunconyelwe ukuthatha amaphilisi okwandisa ama-pathologies angapheli kanye nokuvuvukala. Ukwenqaba umuthi kuyadingeka lapho kukhona abantu abalimele, ezinsukwini ezi-2 ngaphambi nangezinsuku ezi-2 ngemuva kokuhlinzwa.
Ungayithatha kanjani i-Dianormet?
Kunconywa ukuthatha amaphilisi ngokudla noma ngokushesha ngemuva kokudla.
Ngoshukela
Udokotela ukhetha umthamo ngamunye esigulini ngasinye.
Ngokuyalela imiyalo, nesifo sikashukela, irejimeni yokwelashwa ingaba ngale ndlela elandelayo:
- Ngefomu lesifo elizimele le-insulin, isiguli sinconywa ukuthatha ama-500 mg izikhathi ezi-3 ngosuku ngezinsuku ezi-3 zokuqala zokwelashwa. Ezinsukwini eziyi-11 ezilandelayo, umthamo uyanda - 1 g izikhathi ezi-3 ngosuku. Ngemuva kwalokho udokotela uguqula inani le-metformin elithathiwe, ngokuya ngemiphumela yokuhlaziywa: izinkomba zikashukela wegazi nomchamo ziyabhekelelwa. Umthamo wokulondolozwa kwansuku zonke yi-100-200 mg.
- Ngefomu lesifo elincike ku-insulin, irejimeni yokwelashwa ihlinzeka ngenani le-insulin elungiselelwe. Uma umthamo wansuku zonke wezidakamizwa ze-hormonal ungaphansi amayunithi angama-40, khona-ke umthamo we-Dianormet uyefana nesifo sikashukela esingancikeli i-insulin. Ngokwesincomo sikadokotela, umthamo we-insulin uyancipha kancane kancane. Uma isiguli sisebenzisa ama-insulin angaphezu kwama-40 we-insulin ngosuku, khona-ke ukunqunywa komthamo oludingekayo we-metformin kanye nokunquma ukuthi lingakanani isilinganiso se-insulin esingancishiswa kwenziwa ngokucophelela okukhulu futhi ngaso sonke isikhathi ngaphansi kwezimo zokuma.
Imiphumela emibi ye-Dianormet
Ukwemukelwa kwe-Dianormet kungadala imiphumela emibi ezithweni ezahlukahlukene. Isistimu yokugaya ukudla ingaphendula isicanucanu nokuhlanza, ukubukeka kokunambitheka kwensimbi, ukulahleka kokudla, izinhlungu esiswini, i-dyspepsia.
Isiguli esiphuza amaphilisi singaba nezinkinga ngezinqubo ze-metabolic emzimbeni. Lokhu kubonakala ngezimpawu ezilandelayo:
- ubuthakathaka kanye nokubola;
- ukuncishiswa kwengcindezi;
- i-Reflex bradycardia;
- ukuphazamiseka kokuphefumula;
- uma umuthi usetshenziswa isikhathi eside, khona-ke i-hypovitaminosis kungenzeka, lapho kunokuncipha kokuhlushwa kwe-Vitamin B12 ne-folic acid;
- ukusabela komzimba.
Umthelela ekhonweni lokulawula izindlela
Ukwemukelwa kwe-Dianormet akukunciphisi ukugxilisa ukunaka futhi akuphazamisi ijubane lokuphendula kwengqondo. Kepha kwezinye iziguli, ngenxa yokwelashwa isikhathi eside, kungaqhamuka isimo se-hypoglycemic, esiphazamisa amandla okulawula izindlela eziyinkimbinkimbi, kufaka phakathi ngemoto.
Umbuzo wokuthi kungenzeka yini ukuthi isiguli sizibandakanye kulezi zinhlobo zemisebenzi unqunywa ngasese: kuyadingeka ukuhlola impendulo yomuntu lowo muthi.
Imiyalo ekhethekile
Ngesikhathi sokwelashwa nge-Dianormet, kufanele kuqashelwe izinso. Ukuze wenze lokhu, izikhathi ezi-2 ngonyaka, kuhlaziywa ukwenziwa ukuthola okuqukethwe kwe-lactate ku-plasma.
Akunconyelwe ukuthatha lo muthi kubantu abaneminyaka engaphezu kwengu-60 kanye nalabo abasebenza kanzima.
Isabelo sezingane
Umuthi ungasetshenziswa ekwelapheni kwezingane ezineminyaka eyi-10. Ukwelashwa kwenziwa ngemvume kadokotela nangaphansi kokulawulwa kwakhe okuqinile.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Umuthi awuvunyelwe ukusetshenziswa ngabesifazane abakhulelwe nalabo abancelisa usana olusanda kuzalwa.
Isicelo sokusebenza kokulimala kwezinso
Umuthi awubekelwe izifo zeziinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Akunconyelwe ukusebenzisa umuthi ezigulini ezinenkinga yokusebenza kwesibindi.
Akunconyelwe ukusebenzisa umuthi ezigulini ezinenkinga yokusebenza kwesibindi.
I-overdose ye-Dianormet
Ukuthatha umthamo omkhulu womuthi kungadala i-lactic acidosis. Isiguli sidinga ukulashwa ngokuphuthumayo esibhedlela. I-lactate ne-metformin zidlulwa yi-hemodialysis.
Ukuxhumana nezinye izidakamizwa
Ukuphathwa kanyekanye kwe-Dianormet noDanazole kukhathaza i-hyperglycemic coma. Uma kunesidingo, ukwelashwa okunjalo kudinga ukubhekwa njalo kwezinga le-glycemia.
Ukwelashwa akubeki eceleni ukuthatha izidakamizwa eziphuma ku-sulfonylurea, kepha le nhlanganisela ithuthukisa umphumela we-hypoglycemic we-metformin. Kuyadingeka ukuqapha ngokucophelela izinga le-glucose ngenkathi uthatha le mishanguzo.
Ukuthatha i-diuretics ngesikhathi sokwelashwa nge-metformin kungadala i-lactic acidosis. Ama-ACE inhibitors amazinga aphansi kashukela.
Isiguli kufanele sitshele udokotela ukuthi udla ziphi izidakamizwa ukuze udokotela akhethe ukwelashwa okufanele.
Ukuhambisana notshwala
IMetformin notshwala akufanele zithathwe ndawonye. Le nhlanganisela iholela ekuthuthukisweni kwe-lactic acidosis. Ngesizathu esifanayo, kuyadingeka ukushiya umuthi oqukethe i-ethanol.
IMetformin notshwala akufanele zithathwe ndawonye.
Ama-Analog
Ukulungiselela okunomphumela ofanayo - iSiofor, Glibenclamide, Metformin, Glyukofazh, Glukofazh ende, Glipizid.
Imibandela yekhefu lekhemisi
Kubhekiselwa kwimithi kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Abasebenza ekhemisi akufanele bathengise lesi sidakamizwa ngaphezu kwekhawunta, kodwa kwesinye isikhathi bayasithengisa.
Intengo ye-Dianormet
Izindleko zokufakwa ngamathebhulethi angama-30 cishe ngama-ruble ayi-100.
Izimo zokugcina zomuthi
Ekamelweni elinokushisa komoya + 15 ... + 25 ° C.
Gcina umuthi egumbini lokushisa lomoya + + 15 ... + 25 ° C.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emithathu
Umkhiqizi
IPOLFA KUTNO S.A. (EPoland).
Ukubuyekezwa mayelana ne-Dianormet
UMarina Zorina, oneminyaka engu-31, uTyumen: "Ngihlangane kudala noDianormet. Umama unesifo sikashukela, isisindo sakhe siyanda. Wathatha amaphilisi, kepha akusizanga ngalutho saze saya kudokotela omuhle we-endocrinologist. nge-metformin.
Esikhathini esingangenyanga kamuva, umama waba nezinhlungu zenhliziyo, umfutho wegazi lakhe wabuyela kwesejwayelekile, amazinga akhe kashukela abuyele kwesejwayelekile, futhi ukoma kwakhe kwaphela. Into ebaluleke kakhulu ukuthi kancane kancane isisindo saqala ukuwa: isisu sinciphile, imilenze yaba yinto evamile. Kwakungekho miphumela emibi, yize udokotela exwayise ngokuthi kungenzeka. Ngikholwa ukuthi umuthi uyasiza ngesifo sikashukela, kepha akufanele uqale ukwelashwa ngaphandle kokuyalelwa ngudokotela. "
UKonstantin Scherbakov, oneminyaka engama-51, uChelyabinsk: "Ngiqale ukusebenzisa i-Dianormet isigamu sonyaka owedlule. Ubekade echazwe ngudokotela wezengqondo e-aphoyintimenti lapho eqala ukwelashwa. Ngaphambi kwalapho ngiphuze amanye amaphilisi: Angiwuboni umehluko phakathi kwemithi. Ngiphuza umuthi, ngilandela ukudla, ngilawula ushukela njalo, angikhonondi ngempilo yami. "
