Izimo ezisetshenziselwa ukwelapha i-cholesterol ephezulu. Ukulungiselela kwalolu hlobo, okukhiqizwa manje, kunempahla yokunganciphisi i-cholesterol "embi" kuphela, kepha futhi kugqugquzela ukwenziwa kwento ewusizo.
Babekelwa esimweni sokunganakwa kwalesi sifo, uma kunengozi yokuhlaselwa yisifo senhliziyo, unhlangothi. Futhi uma izindlela ezingezona izidakamizwa zingasebenzi.
Umphumela ubonakala ngemuva kwenyanga yokwelashwa nabanikezeli abanjalo. Ngaphandle kwalokhu, ukuthembeka okuphezulu komthelela wabo omuhle akukho. Ngokusho kwezinye izifundo, imiphumela yazo emibi ingaphezu kokuzuzisa.
Noma kunjalo, kukhona iziguli okufanele nakanjani ziphathwe ngama-statins:
- ukuze uvikele ukuhlaselwa yisifo sohlangothi, ukushaya kwenhliziyo;
- nge-ischemia;
- ngemuva kokuhlinzwa enhliziyweni nemithambo yegazi;
- uma umuntu ene-angina pectoris;
- phambi kwe-acute coronary syndrome.
Zibekwa futhi emva kweminyaka engama-40, esimweni sezifo zesifo senhliziyo, kanye nabantu abanezihlobo zabo ezisondelene nabo abashonile ngenxa ye-inhliziyo pathologies.
Imithi yaleli qembu inqunywe ukuthi iqhubeke nempilo yeziguli ezihlushwa i-cholesterol ephezulu. Kodwa leli qiniso alisho ukuthi zibekelwe zonke iziguli ezine-hypercholesterolemia, kodwa kuphela uma kwenzeka zelashwa ngaphandle kokuphumelela.
Ukwelashwa kufanele kunikezwe udokotela kuphela, uma kunesidingo esiphuthumayo. Amanye ama-statins asebenza ngempumelelo yi-Atoris neRosuvastatin. Babekelwa ukungasebenzi kahle kwe-lipid metabolism kanye nesifo senhliziyo.
Ukuqonda ukuthi iyiphi imishanguzo esebenza ngempumelelo kakhulu, i-Atoris noma iRosuvastatin, udinga ukwazi izindlela ezisebenzayo nethonya lazo zombili lezi zidakamizwa nokuthi zihluke kanjani. Womabili la mathuluzi anempendulo enhle engaphezu kweyodwa evela kubasebenzisi.
I-Atoris iyithuluzi elinciphisa ukuqoqwa kwe-cholesterol eyingozi nama-plaque ngosayizi, ehlisa i-atherosclerosis ekukhuleni.
Isithako esikhulu esisebenzayo yi-atorvastatin. Umuthi wokuqala we-atorvastatin yiLiprimar, ne-Atoris umuthi ofanayo, kepha ongabizi kakhulu ngokwemibandela yentengo.
I-Atoris ibekelwe i-cholesterol ephezulu, izingozi eziphezulu zokuthola izifo zohlelo lwethambo nenhliziyo. Ngenxa yesenzo sayo, izingozi zokuqhekeka kwegazi ziyancishiswa.
Izinkomba ezisetshenziswayo:
- I-cholesterol ephezulu kubantu abadala, izingane ngemuva kweminyaka eyi-10.
- Ukuvimbela ukuhlaselwa yinhliziyo.
- Ukuvimbela Unhlangothi
- Ukuvimbela izifo zenhliziyo nemithambo yegazi.
- Umfutho wegazi ophakeme
- Isifo sikashukela mellitus.
- Isikhathi sokululama ngemuva kokuhlinzwa ohlelweni lwezinhliziyo.
Umuthi uxhumana kabi nezinye izidakamizwa. Ukusetshenziswa kwama-statins kanye nezinye izinhlobo zemithi kungadala imiphumela emibi kakhulu ngendlela kwesibindi sokulimala nokusebenza kwezinso. Lokhu kuyiqiniso ikakhulukazi ngemithi elwa namagciwane, izidakamizwa ukhunta, ngokumelene nomfutho wegazi ophakeme, i-arrhythmia, nezidakamizwa eziqinisa amasosha omzimba. Ngaphambi kokuthatha umuthi, udinga ukuxoxa ngalokhu nochwepheshe.
Kwenqatshelwe ukusebenzisa ikhambi lezifo ezinzima zesibindi; ukungabekezelelani komuntu ezintweni eziyinhloko, noma ezisizayo; ngokuqapha: ngotshwala, ukuphazamiseka kohlelo lwe-endocrine, isifo sikashukela, izifo.
I-Rosuvastatin yisidakamizwa esinciphisa i-lipid, esibekiwe uma ezinye izindlela zokwelapha zingasebenzi. Kubhekiselwe nezinye izifo ezithile. Qiniseka ukuthi uphuza umuthi uhambisana nokudla.
Inconyelwe ukusetshenziswa ne:
- I-Hypercholesterolemia yanoma iluphi uhlobo.
- Ukuvimbela izifo zohlelo lwethambo nenhliziyo.
Kubuye kuvame ukubekelwa uhlobo lomndeni lwe-homozygous hypercholesterolemia. Ngaphambi kokuthatha umuthi, isiguli kufanele siguqule ekudleni okukhethekile kwe-cholesterol. Lokhu kuzosiza ukuhambisa ukwelashwa, kufanele kunamathelwe isikhathi eside, mhlawumbe ngemuva kokuphela kokwelashwa.
Futhi, umuthi unezinto eziningi eziphikisana:
- ukungabekezelelani ngakunye kwezinto;
- isifo sesibindi esigabeni esisebenzayo;
- ngesikhathi sokuzala nengane;
- uma kwenzeka ukungabekezelelani kwe-lactose;
- umsebenzi wezinso ongonakalisiwe;
- iminyaka yezingane;
I-Contraindication ozoyisebenzisa ukwelashwa okuhambisana ne-cyclosporine.
Umuthi ngamunye unemiyalo yawo ehleliwe yokusetshenziswa.
I-Atoris iyatholakala ngesimo sethebulethi. Inkambo yokwelapha iqala, imvamisa ngomthamo wamamayela ayi-10 ngosuku. Kungakapheli inyanga, isibalo samathebulethi singandiswa ukwandisa umphumela. Okuphezulu kungama-milligram angama-80 ngosuku.
Eqenjini ngalinye leminyaka, umthamo uhlukile, kuyadingeka ikakhulukazi ukucubungula ngokucophelela inani labantu asebekhulile, abesifazane ngesikhathi sokuya esikhathini. Ngaphezu kwezinzuzo ezisobala, umuthi unemiphumela emibi ethile.
Kuyaphawuleka ukuthi ngokuvamile ukuthatha i-Atoris kubangela ubuhlungu bemisipha, ukugayeka, ikhanda, ukukhathala, ukulimala kancane kwenkumbulo nokucabanga. Ngaphandle kwalokhu, amaphilisi enza okuhle kakhulu kunokulimaza, futhi udinga ukukhansela ukungena kwawo uma kunzima ukubekezelela imiphumela emibi.
Awekho amacala okweqisa izidakamizwa atholakala.
Ukuthatha amaphilisi, udinga ukulandela ukudla okuyisipesheli, uholele indlela yokuphila esebenzayo, kungakuhle ukuthi uhlanganyele nemfundo yomzimba. Uma isiguli sinezinkinga ngesisindo, kufanele wehlise isisindo. Ukwelashwa kuzosebenza kangcono uma umuntu ephila impilo enempilo.
Uma isiguli sikhathazekile ngobuhlungu bemisipha nobuthakathaka obujwayelekile, kufanele uthinte uchwepheshe. Ngesikhathi sokulashwa, udinga ukulawula umsebenzi wesibindi nezinso, ngakho-ke emavikini ayisithupha nayi-12 kufanele ahlolwe.
Kumele kukhunjulwe ukuthi umuthi uyakwazi ukukhuphula izinga likashukela kwabashukela. Gcina umuthi ungafinyeleleki ezinganeni, endaweni emnyama, epholile. Intengo yesidakamizwa eRussia isuka kuma-ruble angama-357
I-Rosuvastatin iyatholakala ngohlobo lwethebhulethi. Kufanele ithathwe ngomlomo, iphuze amanzi amaningi. Kuyadingeka ukuqala ukwelashwa ngamamiligremu ayi-10 ngosuku, uma-ke, uma kunesidingo, ungalukhulisa umthamo. Ekwehlulekeni kwezinso, umthamo kufanele wehliswe ngesigamu ekuqaleni kwenkambo yokwelashwa. Umphumela omkhulu ungabonakala emasontweni amathathu ngemuva kokuqala kokwelashwa. Futhi, umuthi unemiphumela emibi ngesimo:
- i-myalgia;
- i-hypertonicity yemisipha;
- isifo samathambo; isifuba somoya;
- ukuqwasha Ukudana inyumoniya;
- ukwanda kwengcindezi; ukukhathazeka okukhulayo;
- i-rhinitis; angina pectoris; komzimba
- i-anemia yesifo sikashukela;
- i-angioedema;
- isifo sikashukela mellitus; izibuko.
UJaundice ne-hepatitis akuvamile kakhulu. Ukugwema imiphumela emibi, kufanele uhambise ukuthatha umuthi nodokotela wakho futhi uwusebenzise ngokucophelela. Izindleko zomuthi eziseRussia zivela kuma-ruble angama-275.
Ukunquma u-Atoris noma iRosuvastatin: yini engcono kuphela uchwepheshe, ngoba ngamunye wabo angahlukahluka ezicini, futhi athinte umzimba womuntu ngezindlela ezihlukile.
Zombili lezi zidakamizwa zinemiphumela efanayo yezidakamizwa.
Ukufana kwalezi zidakamizwa kuyafana, kepha ezinye kushibhile, umahluko othile.
Uma kunesidingo, angangena esikhundleni somuthi oyinhloko, kepha ukufaka omunye esikhundleni kufanele kuvunyelwe nodokotela. Eziningi zingathathwa njengenye indlela.
Ochwepheshe bahlanganisa i-Atorvastatin, i-Roxer, iRosucard, iSimvastatin, iVasilip, iCardiostatin, iLovastatin njengezibambeli zomuthi ka-Atoris.
Amanani wezidakamizwa ahluke kakhulu. Ezinye zazo zingabizi kakhulu. Ungawathenga ngaphandle kadokotela, kunoma iyiphi ikhemisi.
I-Rosuvastatin nayo ingena esikhundleni:
- Mertenyl;
- IRosucard;
- Rosard;
- Rosulip;
- Roxer;
- I-Tevastor
- Crestor
- Rosistark.
Umuthi ngamunye ungaba indawo yezidakamizwa, ngoba indlela yokusebenza nento eyinhloko icishe ifane. Kunoma yikuphi, udokotela kuphela ongangena esikhundleni somuthi, ngokususelwa kuzinkomba ezijwayelekile zezempilo kanye nenkambo yesifo.
Uma usebenzisa ama-statins, udinga ukubheka ukusebenzisana kwawo nezinye izidakamizwa futhi uqaphele ngokubekezelelwa kwemithi enjalo.
Kumele kuqashelwe ukuthi i-statin ithathwa kuphela ngokuhlanganiswa nezinye izindlela zokwelapha i-hypercholesterolemia: ezemidlalo, ukudla okhethekile, nokuyeka imikhuba emibi.
Mayelana nomuthi iRosuvastatin uchazwe kuvidiyo kule ngxenye.
