Uyini umehluko phakathi kwe-Idrinol neMildronate?

I-Idrinol neMildronate isuselwa esenzweni se-meldonium hydronate, okuyi-analogue yokwenziwa ye-gamma-butyrobetaine. Mina. lezi izidakamizwa ezinconyelwe ukwenza ngcono izinqubo ze-metabolic.

Ukukhetha ikhambi elisebenzayo, udinga ukuzijwayeza hhayi nje kuphela ngokwakhiwa kwemithi, kodwa futhi nezinkomba zazo, ukuphambana kanye nemiphumela emibi. Kepha udokotela kuphela ongakunquma umuthi ngesisekelo se-inhlolovo kanye nemiphumela yokuhlolwa. Ukuzelapha ngokwako akunconywa.

Izici zika-Idrinol

Umuthi ubonakala ngezinga eliphakeme le-bioavailability - 78-80%. Ngaso leso sikhathi, igxilizwa masinyane egazini, futhi ngehora ukugcwala kwalo kuzobe kuphelele. Igcotshwa ikakhulukazi yizinso.

I-Idrinol idonswa ngokushesha egazini, kuthi ngemuva kwehora ukuqoqwa kwayo kube kukhulu.

Udinga ukuqaphela ngenkathi usebenzisa izidakamizwa ezisiza umfutho wegazi ophansi, kanye nama-diuretics nama-bronchodilators.

Izinhlobo zokukhishwa - amaphilisi noma umjovo. Ngokuqondene nefomu elivalekile, umuthi ukhiqizwa ngomthamo we-250 mg. Umkhiqizi - iSotex Pharmfulama CJSC, ebhaliswe eRussia.

Isimilo seMildronate

Lesi akusona isidakamizwa esisha. Yaqala ukwenziwa emuva ngeminyaka yo-1970. eLatvia. Kuqala esetshenziswa ekwelapheni kwezilwane, kanye namandla ayo ekwelapheni i-atherosclerosis ne-CHF kwatholakala ngemuva kwesikhashana. Namuhla, lo muthi usakhiqizwa yinkampani yaseLatvia iJSC Grindeks.

Uhlobo oluphambili lokukhishwa luyisixazululo somjovo esingu-10% namaphilisi we-gelatin aqinile. Ngaphakathi kuyimpuphu emhlophe.

Ukuqhathanisa kwe-Idrinol neMildronate

Zombili lezi zidakamizwa zinokwakheka okufanayo. Isakhi esiyinhloko yi-meldonium. Yize kungenxa yesikhalazo se-Olimpiki, kubonakala ngabaningi njengabaphindaphindayo, imiphumela ehlukahlukene yamakhemikhali entweni ibanzi. Abasubathi bangabelwa ukwenza ngcono ukuhamba kwegazi, kwandise ukubekezelela komzimba ekucindezelekeni. Umuthi unikeza umzimba amandla futhi uthambisa isistimu yezinzwa ephakathi.

Zombili lezi zidakamizwa zithuthukisa ukusebenza kwenhliziyo.

Njengoba le mishanguzo isuselwa entweni efanayo, zisebenza ngendlela efanayo - zithuthukisa ukusebenza kwenhliziyo, zenze ukuhamba kwegazi kube okujwayelekile ezimweni zokulimala kobuchopho. Izidakamizwa zinconywa i-atherossteosis, isifo sikashukela.

Ukusetshenziswa kwento efanayo esebenzayo ekwakhiweni, nakumthamo olinganayo, kuholele ekubeni hhayi kwezinkomba ezifanayo zokusebenzisa, kodwa futhi kucishe kube ne-contraindication efanayo kanye nemiphumela emibi.

Yini evamile?

Isici esijwayelekile sezidakamizwa ukuba khona kwe-meldonium. Lesi sakamuva sinemiphumela eminingana yemithi, efaka:

• ukubuyiselwa kokulethwa komoya-mpilo kanye nokwanda kokusetshenziswa kwawo ngamaseli;
• umphumela we-cardioprotective (uthinta kahle umsipha wenhliziyo);
• ukukhulisa amandla omzimba ekusebenzeni ngokomzimba nangokwengqondo;
• ukusebenza kwe-immune immune;
• ukuncishiswa kwezimpawu zokuxineka ngokomzimba nangokwengqondo;
• kunciphise amathuba ezinkinga zangemva kokuqothuka.

I-Meldonium nayo isetshenziswa ekwelapheni isifo sikashukela, kepha njengengxenye yokwelapha okuyinkimbinkimbi. Kunomphumela omuhle kumetabolism ye-lipids ne-glucose, lokhu kwaqinisekiswa izifundo ezenziwa eminyakeni yokuqala yo-2000. Ngaphezu kwalokho, amalungiselelo e-meldonium asiza ukulwa nesifo sikashukela se-polyneuropathy.

Izidakamizwa zandisa amandla emisebenzi yengqondo.

Yomibili le mishanguzo ikhulisa ukumelana nokuzivocavoca ngokomzimba.

I-Idrinol neMildronate banciphisa izimpawu zokuxineka kwengqondo.

Izidakamizwa zenza ukuthi umzimba ungalimali.

Ekwelashweni okuyinkimbinkimbi, iMeldonium isetshenziswa ekwelapheni isifo sikashukela.

Zombili lezi zidakamizwa zinomphumela omuhle esimweni senkumbulo.

Lapho udla izidakamizwa, inkumbulo yathuthuka, inomphumela onenzuzo kumakhono wokuqonda komuntu.

Ngomonakalo omkhulu we-ischemic we-myocardium, i-meldonium ibambezela inqubo ye-tisc necrosis futhi isheshise izinqubo zokuvuselela umzimba. Ekuhlulekeni kwenhliziyo okungapheli, umsebenzi we-myocardial uyathuthuka. Ngaphezu kwalokho, iziguli zikwazi ukubekezelela kangcono ukusebenza komzimba, inani labo lokuhlaselwa kwe-angina liyancishiswa.

Imiphumela emibi izocishe ifane. Lokhu:

• dyspepsia (isicanucanu, ukuhlanza, ukushisa kwenhliziyo);
• ukuphazamiseka kwesigqi senhliziyo, kufaka phakathi i-tachycardia;
• ukuphazamiseka kwengqondo
• ukungezwani komzimba (ukulunywa kwesikhumba, i-hyperemia, i-urticaria, noma ezinye izinhlobo zokuqubuka);
• izinguquko ekucindezelweni kwegazi.

Kepha zombili lezi zidakamizwa zibekezelelwa kahle. Ucwaningo luye lwabonisa ukuthi ezigulini ezinokugula okungapheli kwe-cerebrovascular insuffeed, ezinye izifo zenhliziyo, azange kube nezehlakalo zokuyekiswa kwamalungiselelo e-meldonium ngenxa yokuthuthuka kwemiphumela emibi.

Izinkomba zokusetshenziswa kwe-Idrinol ne-Mildronate ngokuyisisekelo ziyahlangana:

• isikhathi sokusebenza - ukusheshisa izinqubo zokubuyisa;
• izifo zenhliziyo ezi-coronary, kufaka phakathi i-angina pectoris, isimo sangaphambi kokufakelwa kwamazinyo kanye nokubumbeka ngokuqondile;
• i-retinopathy ngesifo sikashukela i-mellitus noma i-hypertension;
• ukwehluleka kwenhliziyo okungamahlalakhona (CHF);
• ukucindezelwa ngokomzimba, kufaka phakathi kwalabasubathi abangochwepheshe;
• imivimbo kanye nokuswelakala kwe-cerebrovascular okubangelwa ukuphazamiseka kokujikeleza kwengqondo okuqinile nangokungapheli (izidakamizwa zifakwa ohlelweni oluyinkimbinkimbi lokwelapha);
• I-syndrome yokuhoxiswa kotshwala (futhi njengengxenye yokwelashwa okuyinkimbinkimbi);
• isifo senhliziyo.

Ngesikhathi sokulashwa, isicanucanu nokuhlanza kungenzeka.

Kwezinye izimo, imithi ibanga ukushaya kwenhliziyo.

Kokubili iMildronate ne-Idrinol kungavusa ukungahambi kahle komzimba.

Imithi imiselwe isifo sokuhoxiswa kotshwala.

Le mishanguzo isiza ngokuphazamiseka kokujikeleza kwengqondo okungapheli ebuchosheni.

Akunconywa ukuthatha izidakamizwa ngesikhathi sokukhulelwa.

Izidakamizwa azinconywa kubantu abangaphansi kweminyaka engu-18 ubudala.

Kwesinye isikhathi izidakamizwa zibekelwa ukungahambi kahle kokujikeleza komzimba emithanjeni ye-retina, ukuba khona kwe-thrombosis, kanye ne-hemorrhages.

Ukuxhumana phakathi kwe-Mildronate ne-Idrinol kucishe kufane ngokuphelele. Lokhu kufaka phakathi:

• ukukhuphuka kwengcindezi ye-intracranial;
• hypersensitivity to meldonium kanye nezinto ezisizayo zomuthi.

Ucwaningo oluphelele oluzokhombisa ukuphepha kokusetshenziswa kwamalungiselelo we-meldonium kwabesifazane abakhulelwe alwenziwe. Ngakho-ke, i-Mildronate ne-Idrinol ayinconywa kubo. Okufanayo kusebenza ekusetshenzisweni kwabo ezinganeni nakwintsha eneminyaka engaphansi kwengu-18.

Inkambo yokwelashwa inqunyelwa udokotela, kucatshangelwa izici zalesi sifo, iminyaka isiguli, isimo sayo esivamile, njll. Okuningi kuya ngesimo sokulawula umuthi. Isibonelo, ku-ophthalmology, isixazululo somujovo sisetshenziselwa ukuphazamiseka kokujikeleza kwesitho esibuhlungu ku-retina. Isikhathi esiphezulu sokwelashwa kuleli cala yizinsuku eziyi-10.

Uma kwenzeka ukungasebenzi kahle kwesibindi, zombili lezi zidakamizwa zibekwe ngokuqapha, isinqumo sokugcina sihlala nodokotela.

Uyini umehluko?

Ukuzilolonga ngemitholampilo kukhombisa ukuthi akukho mehluko phakathi kweMildronate ne-Idrinol. Bacishe babe nobubanzi obufanayo kanye ne-contraindication. Ngokuqondene nemiphumela emibi, ibuye ihlangane ngokuyisisekelo. Umehluko ukuthi iMildronate iyivelakancane, kepha ingadala ikhanda nokuvuvukala.

Kukhona izifundo ezibonisa ukuthi iMildronate ayisetshenziselwa nje kuphela ukuqeda ukuphazamiseka kokujikeleza kwegazi ngemuva kwesifo sohlangothi, kodwa futhi nokwelapha izimo ezicindezelayo ezihambisana nalesi sifo. Umuthi awuthinti kuphela ukuphazamiseka kwezimoto kanye nokukhubazeka kwengqondo, kodwa futhi nomkhakha wengqondo. Ngakho-ke, kwandisa ukusebenza kahle kohlelo lokuvuselela kabusha. Kwa-Idrinol, azikho izifundo ezinjalo ezenziwayo.

Yikuphi okushibhile?

Intengo yeMildronate isuka kuma-ruble angama-300 ngomthamo wama-250 mg kuya kuma-ruble angama-650 wama-500 mg amaphilisi. Idrinol ishibhile. Kwiphakheji elinamaphilisi we-250 mg wezinto ezisebenzayo, isiguli sizokhokha cishe ama-ruble angama-200.

Yini i-idrinol engcono noma i-Mildronate?

Akunakwenzeka ukuphendula ngokungathandabuzi umbuzo wokuthi yikuphi okungcono, i-Idrinol noma iMildronate. Yomibili le mishanguzo ifundwe, inamandla cishe afanayo, inesilinganiso esifanayo futhi ibekezelelwa kahle yiziguli.

Le mishanguzo ine-analogues. Ngaphezu kwalokho, akhiqizwa eRussia, ngokwesibonelo, uCardionate. Kepha i-Idrinol neMildronate zibhekwa njengezisebenza ngempumelelo. Ngokunikezwa iqiniso lokuthi i-Idrinol ishibhile, ivame ukubekwa ngaphezulu.

Ukubuyekezwa kweziguli

USvetlana, oneminyaka engama-42, uRyazan: "Bathola isifo sikashukela sohlobo lwe-2. Udokotela wathi uMildronate phakathi kwezinye izidakamizwa. Kubekezelelwa kahle, akubanga nokuzwana kukho. Ngingasho nje ukuthi kukhona ukuthuthuka ngokuya ngombono."

UVladislav, oneminyaka engama-57, eMoscow: "Bangeniswe esibhedlela bengakashayi indiva, banikezwa izidakamizwa eziningi, kubandakanya noMildronate. Ngokuthi isimo esibi kakhulu sigwenyiwe, umuthi usebenza kahle."

UZinaida, oneminyaka engama-65, uTula. "U-Idrinol ubekade elungiselelwe isifo senhliziyo. Umuthi omuhle, ngaphandle kwemiphumela emibi, futhi kukhona ukuthuthuka enhlalakahleni."

Yomibili le mishanguzo ifundwe, inamandla cishe afanayo, inesilinganiso esifanayo futhi ibekezelelwa kahle yiziguli.

Ukubuyekezwa kodokotela mayelana ne-Idrinol ne-Mildronate

UVladimir, udokotela wezinhliziyo, eMoscow: "Ngokungaphatheki kahle kwenhliziyo ngichaza ukuthi iMildronate iyasebenza futhi iyabekezelelwa. Kukhona izifundo ezithinta isimo sengqondo, ukunakwa kuyathuthuka."

U-Ekaterina, udokotela wezifo zemizwa, iNovosibirsk: "Ngibeka iMildronate ngezingozi ze-cerebrovascular. Kodwa ungasifaka isidakamizwa nge-Idrinol - ishibhile."