Abantu abaningi bayayithanda umehluko phakathi kwezidakamizwa zeGlucofage neGlucophage Long. Yomibili le mishanguzo ithathwa njenge-biguanides, i.e. ushukela wegazi ophansi.
Izindlela zibekelwe ukuqinisa imetabolism kubantu, lapho ukuzwela kwezakhiwo zamangqamuzana ukuya ku-insulin kuba kubi kakhulu, futhi ukugcwala kwengcindezi kukhuphuka, inani lama-glucose landa. Umphumela wokwelapha wazo zombili izidakamizwa uyafana.
Ngabe isebenza kanjani i-glucophage?
Umuthi uwumuthi we-hypoglycemic. Yehlisa inani loshukela egazini, elisetshenziswa ekwelapheni isifo sikashukela. Amathebhulethi anombala omhlophe, oyindilinga nowokuma kwesimo.
IGlucophage ne-Glucophage Long zibhekwa njenge-biguanides, i.e. ushukela wegazi ophansi.
Isithako esikhulu esisebenzayo ekwakhekeni kwe-glucophage yi-metformin. Le khompiyutha iyi-greatuanide. Inomphumela we-hypoglycemic ngenxa yokuthi:
- ukushuba kwezakhiwo zamaselula ukwanda kwe-insulin, ushukela udonswa kangcono;
- ukuqina kokukhiqiza ushukela ezinhlakeni zamaselula kwesibindi kuyancipha;
- kukhona ukubambezeleka kokufakwa kwe-carbohydrate ngamathumbu;
- izinqubo ze-metabolic zamafutha ziyathuthuka, izinga lokuhlushwa kwe-cholesterol liyancipha.
I-Metformin ayibuphazamisi ubukhulu be-insulin synthesis eyenziwe ngamaseli we-pancreas, umuthi awukwazi ukuvusa i-hypoglycemia.
Ngemuva kokusebenzisa umuthi, isakhi esisebenzayo sidlula emathunjini singena egazini elijwayelekile. I-Bioavailability icishe ibe ngama-60%, kepha uma udla, ke inkomba iyancipha. Inani eliphezulu le-metformin egazini libonakala ngemuva kwamahora ayi-2,5. Leli khompiyutha licutshungulwa ngokwengxenye kwesibindi futhi lidalulwe izinso. Isigamu sonke somuthi siphuma emahoreni angama-6-7.
I-Glucometer Van Touch - ukubuyekezwa nokuqhathaniswa kwamamodeli.
Kuphi futhi kanjani ukufaka i-insulin?
Ukuqhathaniswa kwamamitha wemitha ye-Accu-Chek - okuningi kule ndatshana.
Isici Glucophage Isikhathi Eside
I-ejenti ye-hypoglycemic eqenjini le-Biguanide. Umuthi uyatholakala ngesimo samathebulethi ngesenzo esenziwe isikhathi eside. Ithuluzi futhi lihloselwe ukwehlisa amazinga kashukela egazini. Ingxenye esebenzayo yesidakamizwa nayo i-metformin.
Ithuluzi lisebenza ngokufanayo neGlucofage: alikhulisi ukukhiqizwa kwe-insulin, alikwazi ukuvusa i-hypoglycemia.
Uma usebenzisa i-Glucofage Long, ukufakwa kwe-metformin kuhamba kancane kunasesimweni samathebulethi ngesenzo esisejwayelekile. Ukuqoqwa okuphezulu kwengxenye esebenzayo egazini kuzofinyelelwa ngemuva kwamahora angama-7, kepha uma inani lempahla ethathiwe lingama-1500 mg, khona-ke isikhathi sesikhathi sifinyelela emahoreni ayi-12.
Uma usebenzisa i-Glucofage Long, ukufakwa kwe-metformin kuhamba kancane kunasesimweni samathebulethi ngesenzo esisejwayelekile.
Ingabe i-Glucophage ne-Glucophage Isikhathi eside yinto efanayo?
IGlucophage ingumuthi osebenzayo we-hyperglycemia. Ngenxa yoku-metabolism okuthuthukile, amafutha ayingozi awanqwabelani. Umuthi awuthinti ubukhulu bokukhiqizwa kwe-insulin, ngakho-ke unqunyelwe ngisho nakubantu abangenaso isifo sikashukela.
Omunye umenzeli we-hypoglycemic yi-Glucophage Long. Lokhu kucishe kufane nomuthi owedlule. Umuthi unezakhiwo ezifanayo, kuphela umphumela wokwelapha uhlala ngaphezulu. Ngenxa yevolumu enkulu yengxenye esebenzayo, idonswa isikhathi eside emzimbeni, futhi umphumela wayo uhlala isikhathi eside.
Zombili izidakamizwa:
- ukusiza ekwelapheni isifo sikashukela;
- ukuzinza ukugxila kwe-glucose ne-insulin;
- umphumela onenzuzo kumetabolism nokusetshenziswa kwama-carbohydrate ngumzimba;
- vikela izifo zemithambo, yehlisa i-cholesterol.
Yomibili le mishanguzo ivunyelwe ukuthi iphuzwe kuphela ngemuva kokuqokwa ngudokotela, ukuvikela ukukhula kwezinkinga emzimbeni.
Ukuqhathaniswa kweGlucophage ne-Glucophage ende
Naphezu kweqiniso lokuthi yomibili imishanguzo ibhekwa njengethuluzi elifanayo, inakho ukufana kanye nokungafani.
Ukufana
Yomibili le mikhiqizo yenziwa ngabakwa-MERCK SANTE abavela eFrance. Emakhemisi, awahlakazeki ngaphandle kwencwadi kadokotela. Umphumela wokwelapha wezidakamizwa uyafana, isakhi esiyinhloko kuzo zombili yi-metformin. Ifomu lomthamo - amaphilisi.
Yomibili le mishanguzo ivunyelwe ukuthi iphuzwe kuphela ngemuva kokuqokwa ngudokotela, ukuvikela ukukhula kwezinkinga emzimbeni.
Ukusetshenziswa kwemithi enjalo kuholela ekucindezelweni ngokushesha kwezimpawu ezenzeka ngesimo se-hyperglycemic. Isenzo somusa sikuvumela ukuba uthonye inkambo yesifo, izinkomba zoshukela, futhi ukwenze lokhu ngesikhathi esifanele.
Izinkomba eziphambili zokusetshenziswa emithini ziyefana. Izidakamizwa ezinjalo zisetshenziswa kumacala alandelayo:
- thayipha isifo sikashukela se-2 lapho ukwelashwa kokudla kungasizi;
- ukukhuluphala
Izidakamizwa zibekelwe ushukela ezinganeni ezineminyaka engaphezu kwe-10. Kumntwana omncane kunale minyaka (kufaka phakathi izingane ezisanda kuzalwa), lesi sidakamizwa asifanele.
Ukuxhumanisa ukusetshenziswa kwemithi kuyafana:
- coma;
- isifo sikashukela sikashukela;
- umsebenzi wezinso ongonakalisiwe;
- izinkinga ekusebenzeni kwesibindi;
- ukwanda kwezifo ezahlukahlukene;
- umkhuhlane;
- izifo ezibangelwa izifo;
- ukomisa;
- ukuvuselelwa emuva kokulimala;
- ukuvuselelwa emuva kokusebenza;
- ukudakwa kotshwala;
- izimpawu ze-lactic acidosis;
- ukukhulelwa nokuqunjelwa;
- hypersensitivity kuzakhi zomuthi.
Kwesinye isikhathi imithi ivusa imiphumela emibi:
- Izinkinga zokugaya ukudla: isicanucanu, ukulahleka kwesifiso, isifo sohudo, ukuthopha;
- i-lactic acidosis;
- i-anemia
- urticaria.
Nge-overdose ye-Glucophage noma i-Glucophage Long, kuzovela lezi zimpawu ezilandelayo:
- isifo sohudo
- ukuhlanza
- umkhuhlane;
- Ubuhlungu emgodini wesisu;
- ukushesha kokuphefumula;
- Izinkinga ngokuxhumana kokunyakaza.
Kuzona zonke lezi zimo, kufanele uyeke ukuthatha umuthi futhi ushayele i-ambulensi. Ukuhlanza kwenziwa nge-hemodialysis.
Uyini umehluko?
Umehluko phakathi kwezidakamizwa ulele ezingomeni zabo, yize ingxenye eyinhloko ifana. I-Povidone ne-magnesium stearate zikhona eGlucofage njengezihlanganisi ezisizayo. Igobolondo ngokwalo lenziwe nge-hypromellose. Ngokuqondene ne-Glucofage Long, ihlanganiswe nezinto ezifana:
- i-microcrystalline cellulose;
- i-hypromellosis;
- i-sodium carmellosis;
- i-magnesium stearate.
Ukuvela kwamatafula kuhlukile. Ijamo liyi-biconvex eyindilinga ene-whitish hue, futhi uma umuthi unesenzo esisebenza isikhathi eside, amaphilisi amhlophe qwa, kepha awenhliziyo.
Umehluko phakathi kwezidakamizwa ulele ezingomeni zabo, yize ingxenye eyinhloko ifana.
Izici zokusetshenziswa kwayo zombili le mithi ziyatholakala. IGlucophage kufanele ithathwe nge-500 mg. Ngemuva kwamaviki ama-2, khuphula inani kancane kancane. Umthamo ojwayelekile ngu-1.5-2 g, kepha ungabi ngaphezu kwe-3 g ngosuku. Ukunciphisa ubungozi bokuphendula okungahambi kahle, inani eliphelele lihlukaniswe izikhathi ezingama-2-3 ngosuku. Amathebulethi kufanele athathwe ngokushesha ngemuva kokudla.
Ngokuqondene ne-Glucofage Long, umthamo unqunywa ngudokotela uqobo esigulini ngasinye. Isimo sempilo esijwayelekile, isimo salesi sifo kanye nokuqina kwaso, izimfanelo zomzimba, ubudala kuyabhekelelwa. Kepha ngasikhathi sinye, ngenxa yokuthi umuthi unomphumela wesikhathi eside, ukuphathwa kwamathebulethi kwenziwa kuphela 1 ngosuku ngosuku.
Yikuphi okushibhile?
IGlucophage ingathengwa emakhemisi ngama-ruble ayi-100. noma kubiza kancane, kepha nge-Glucofage Long, intengo iqala kusuka kuma-ruble angama-270. eRussia.
Yikuphi okungcono - i-Glucofage noma i-Glucofage Long?
Le mishanguzo inomphumela omuhle ohlelweni lwezinhliziyo, isiza ukulwa ngamakhilogremu angeziwe, ithuthukise inhlala-kahle futhi ibuye ijwayele ukugcwala kweglucose egazini elinoshukela. Kepha, yikuphi okungcono esigulini, kudokotela kuphela onqumayo, kuya ngesifo, isimo saso, ubulukhuni, isimo sesiguli, ukuba khona kwe-contraindication.
Zombili lezi zidakamizwa zinezici ezifanayo ezisebenzayo, izakhiwo ezizuzisayo, imiphumela emibi, i-contraindication.
Ukubuyekezwa kodokotela
U-Aydinyan S.K., udokotela obambelela nge-endocrinologist: "Nginikeza ngentshiseko iGlucophage yesifo sikashukela sohlobo 2 nokukhuluphala. Ukusebenza kahle kwezempilo sekufakazelwe. Umuthi unentengo engabizi."
U-Nagulina S. S., udokotela we-endocrinologist: "Umuthi omuhle wesifo sikashukela sohlobo lwe-2. Ngaphezu kwalokho, isetshenziswa ekwelashweni okuyinkimbinkimbi kokukhuluphala. Uma kuqhathaniswa neglucophage ejwayelekile, imiphumela emibi ayivamile."
I-Glucofage ne-Glucophage Ukubuyekezwa kweziguli ezinde
UMaria, oneminyaka engama-28 ubudala: "Udokotela unqume ukuthi i-Glucofage yehlise isisindo. Thatha ithebhulethi eyi-1 izikhathi ezi-2 ngosuku. Ekuqaleni ngazizwa ngigula kancane, kodwa-ke yadlula. Manje ibekezelelwa kahle. Isisindo siyancipha kancane kancane."
UNatalia, oneminyaka engama-37: "U-endocrinologist unqume i-Glucofage Long ngenxa yokukhuluphala kanye nokuthuthukiswa kwerayisi sikashukela (bobabili abazali banalesi sifo.) Ekuqaleni wayesaba imiphumela emibi eminingi. Esontweni lokuqala ngazizwa ngicashile ekuseni, kodwa emva kwalokho konke kwabuya kwelejwayelekile. Ukuzivocavoca umzimba, kudliwe okuncane. Ezinyangeni ezintathu ezedlule, kwehle ama-8 kg. "
