I-R-lipoic acid (amanye amagama - i-lipoic, i-alpha-lipoic noma i-thioctic acid) iyi-antioxidant yemvelo ne-anti-immune genet evikela ubuchopho, isiza ekulahlekelweni yisisindo, inciphise isifo sikashukela, inciphise ingozi yesifo senhliziyo futhi ikhulule izinhlungu Futhi lezi ngezinye nje zezinzuzo eziningi zale "antioxidant yendawo yonke."
Igama Lezwe elingafanele
I-Thioctic acid.
I-Thioctic acid i-antioxidant yemvelo ne-anti-immune genet.
I-ATX
Ehlukweni, i-ATX inekhodi A16AX01. Lokhu kusho ukuthi lesi sidakamizwa sisetshenziselwa ukwelapha izifo zesibindi kanye nokwenza ngcono imetabolism.
Khipha amafomu nokwakheka
Kutholakala kwifomu lethebhulethi, izingcezu ezingama-50 iphakethe ngalinye. Okuqukethwe kwezinto ezisebenzayo kungu-12 mg noma 25 mg. Le acid ingatholwa nangamakhompiyutha nanjengesisombululo somjovo.
Isenzo se-Pharmacological
I-Lipoic acid yi-molecule encane engenawo amaprotheni ehlangana ngendlela ekhethekile namaprotheni ahambisanayo. Le asidi idlala indima enkulu ekulinganiselweni kwamandla omzimba. Ngombono we-biochemical umbono wawo, umphumela wawo uyefana nesenzo samavithamini we-B. Kuthuthukisa ukusebenza kwesibindi, kungumenzeli wokukhuculula ubuthi ngosawoti osindayo nezinye izinto ezidakayo.
I-Pharmacokinetics
I-Bioavailability ingama-30%. Ihanjiswa ngenani lama-450 ml / kg. I-80-90% isuswe yizinso.
I-Lipoic acid yi-molecule encane engenawo amaprotheni ehlangana ngendlela ekhethekile namaprotheni ahambisanayo.
Izinkomba zokusetshenziswa
I-Alpha lipoic acid inezinto eziningi ezisebenzayo ongazisebenzisa. Iningi lezindawo zokwelapha libangelwa ukuthi le asidi iyi-antioxidant.
Ibhebhethekisa izinga elijwayelekile lama-hormone akhiqizwa i-gland yegland
Uma impilo ye-yegilo yegilo ikhubazekile, khona-ke ukukhishwa kwama-hormone kuphumela ngaphandle kokulawulwa. Ucwaningo lwango-2016 lwathola ukuthi i-alpha lipoic acid ethathwe ne-quercetin ne-resveratrol yasiza ukulinganisela amazinga e-hormone.
Usekela Izempilo Yezempilo
Uma kunokungasebenzi kahle ohlelweni lwezinzwa oluzungezile, khona-ke ukugabha noma ukugabha kungenzeka. Lokhu kungaphazamisa ukuhlangana komuntu kanye nekhono lokubamba izinto. Ngokuhamba kwesikhathi, lokhu kungathuthuka futhi kubangele ezinye izinkinga. Ucwaningo luye lwabonisa ukuthi le acid ingayisekela impilo yohlelo lwezinzwa, ikakhulukazi i-periphery yayo.
Usekela Umsebenzi Wenhliziyo
Olunye ucwaningo lukhombisa ukuthi i-thioctic acid ivikela amaseli e-arterial futhi igcina impilo yawo. Le acid nayo inomthelela ekujikelezweni kwegazi okujwayelekile, okusiza ekugcineni impilo yenhliziyo.
Kuvikela izicubu ekucindezelekeni okubangelwa ukuzivocavoca
Amanye ama-Workout angasheshisa inqubo yemiphumela e-oxidative emzimbeni, ethinta kabi isimo sezicubu nemisipha, mhlawumbe ukubukeka kobuhlungu. Ama-Nutrients anezakhi ze-antioxidant, njenge-R-lipoic acid, angawunciphisa lo mphumela.
Usekela umsebenzi wesibindi
Ucwaningo oluningi lukhombisa ukuthi le acid inomthelela ekusebenzeni okujwayelekile kwesibindi futhi isiza ukubhekana nokudakwa komzimba.
Ukudla okwengeziwe kwalesi sidakamizwa kungaqinisa inkumbulo.
Iqinisa inkumbulo futhi isekela impilo yobuchopho
Lapho umuntu eba mkhulu, kukhiqizwa i-lipoic acid emincane emzimbeni. Ukuvikelwa kuma-radicals mahhala kuyenziwa buthaka. Lokhu kungadala ukulimala kwengqondo. Ukungezwa nalesi sidakamizwa kungakhulisa inkumbulo nempilo yengqondo yonke.
Kuthuthukisa Impilo Yesikhumba
I-Alpha lipoic acid ingasiza abantu abomile, abacasulayo, ababomvu, noma abanemifantu esikhunjeni sabo.
Kusiza inqubo yokuguga.
Njengoba iminyaka yethu ikhula, umphumela oxidative uyanda futhi uhlanganisa amaseli amaningi emizimba yethu. Ucwaningo luye lwabonisa ukuthi lesi sidakamizwa singasiza ukulinganisa le nqubo, sibambezele ukuqala kwezifo ezihambisana nemisebenzi yenhliziyo, ukuvikela ubuchopho ezifweni ezihambisana nokuwohloka komqondo, ukulahleka kwememori.
Isekela Igazi Lempilo Elinempilo
Izinga le-insulin eliphansi lingadala izinkinga zempilo ngenxa yokuqunjelwa kweglucose egazini. Ucwaningo luqinisekisile ukuthi i-thioctic acid iyasiza ukulwa namazinga kashukela egazini.
Isekela Isisindo Somzimba Onempilo
Ukubuyisa isisindo sakho kokujwayelekile, udinga ukuvivinya umzimba njalo, ukudla okufanele. Izithasiselo ezinjenge-alpha lipoic acid zingakhuphula umthelela wendlela yokuphila enempilo emzimbeni womuntu.
Contraindication
Akukho mibiko eminingi kangaka yale khambi. Lokhu kufaka ukukhulelwa, ukukhipha isisu, kanye nokuphazamiseka kwengqondo. Kunedatha elincane ngemiphumela yesidakamizwa emzimbeni wezingane. Nge-hypersensitivity ezingxenyeni zomuthi, ukusetshenziswa kuyaphulwa.
Ungayithatha kanjani i-R-lipoic acid
Kutholakala ngesimo samathebulethi, amaphilisi noma umjovo. Ithebhulethi kanye namaphilisi kuyaphuzwa ngokudla noma ngamanzi amaningi, futhi isisombululo sikhonjelwa ngabadonsa ngokuqina.
Ngaphambi kokudla ngemuva kokudla
Kunconywa ukuthatha ngokudla noma ngamanzi amaningi.
Ngoshukela
Iziphakamiso zokusetshenziswa kwe-acid ezinhlotsheni zesifo sikashukela ezinsukwini 1 no-2 zinganikezwa kuphela ngudokotela ohambelayo.
Imiphumela emibi ye-R-lipoic acid
Kumthamo olinganiselayo, awuthinti kabi. Imiphumela emibi ejwayelekile: ukulunywa, ukuqubuka, eminye imiphumela yokungezwani komzimba kanye nenausea, Ubuhlungu besisu.
Iziphakamiso zokusetshenziswa kwe-acid ezinhlotsheni zesifo sikashukela ezinsukwini 1 no-2 zinganikezwa kuphela ngudokotela ohambelayo.
Umthelela ekhonweni lokulawula izindlela
Ukushayela akuvinjelwe, kepha ngenxa yokuthi kungenzeka ube nesicanucanu nobuhlungu besisu, okungathinta ukunakwa, kunconyelwa ukuba uqaphele ikakhulukazi.
Imiyalo ekhethekile
Ngaphambi kokusebenzisa lo muthi, thintana nochwepheshe.
Sebenzisa ebudaleni
Leli khambi lingavimba ezinye izinkinga zempilo ezihambisana nokuguga.
Isabelo sezingane
Kukhona ucwaningo oluncane nolwazi mayelana nemiphumela yesidakamizwa emzimbeni wezingane, ngakho-ke ukuzilawula akukunconyelwe ezinganeni. I-overdose ithatha umuthi inani elingaphezu kwama-50 mg nge-1 kg yesisindo.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kuqinisekisiwe.
Ukweqisa kwe-R-Lipoic Acid
Uma i-overdose, imiphumela emibi iyaqina.
Kukhona ucwaningo oluncane nolwazi mayelana nemiphumela yesidakamizwa emzimbeni wezingane, ngakho-ke ukuzilawula akukunconyelwe ezinganeni.
Ukuxhumana nezinye izidakamizwa
Ngcono umphumela wokulwa nokuvuvukala we-glucocorticoids. Yehlisa umphumela we-chisplatin. Futhi kwandisa ukusebenza kwama-insulin kanye nama-hypoglycemic agents.
Ukuhambisana notshwala
Kusetshenziswa ekwelapheni okuyinkimbinkimbi ekwelapheni ukuluthwa utshwala.
Ama-Analog
Ukufana kwezidakamizwa kufaka phakathi:
- I-Thioctacid;
- Tiogammu;
- I-Espa lipon;
- I-R-alpha lipoic acid, i-biotin;
- Thiolipon nabanye
Imibandela yekhefu lekhemisi
Kuyatholakala ngaphandle kadokotela.
Intengo
Amanani acishe alesi sidakamizwa:
- I-Lipoic acid, amaphilisi angu-25 mg, ama-50 ama-pcs. - ama-ruble angaba ngu-50;
- I-Lipoic acid, amaphilisi ayi-12 mg, ama-50 ama-pcs. - cishe ama-ruble angama-15.
Izimo zokugcina zomuthi
Imibandela okufanele ihlangatshezwe:
- indawo eyomile;
- ukuntuleka kokukhanya;
- ukuvikela izingane;
- izinga lokushisa elingeqi ku-25 ° C.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emithathu
Umkhiqizi
IMarbiopharm, eRussia.
Ukubuyekezwa
Odokotela
U-Iskorostinskaya O. A., udokotela wezifo zamazinyo, iVladivostok: "Ikhambi elisezingeni eliphezulu elinezinto ezingama-antioxidant (ngokwesibonelo, lithambisa izinhlobo ze-oxygen ezisebenzayo), kunengqondo ukuthatha iziguli ezinesifo sikashukela njalo."
Lisenkova O. A., udokotela wezifo zemizwa, uNovorossiysk: "Ukubekezelelana okuhle nokusebenza kahle ngokweqile uma kwenzeka kutholakala ukuthi kusetshenziselwa ukungena ngaphakathi. Kusetshenziselwa ukwelapha izinkinga zesifo sikashukela i-mellitus (ikakhulukazi, isifo sikashukela se-neuropathy, i-polyneuropathy)."
Iziguli
U-Alisa N., Saratov: "Umuthi omuhle. Ushibhile, kodwa uyasebenza. Ukuthatha isikhathi eside ngaphandle kwemiphumela emibi kungenzeka."
USvetlana Yu., UTyumen: "Babeka i-thioctic acid, bathatha isibhebhe 1 ngosuku izinyanga ezimbili. Umuzwa wokugcwala wanyamalala, futhi ngazizwa ngilangazelela njalo lo muthi."
Ukulahlekelwa isisindo
I-Anastasia, eChelyabinsk: "Ngemuva kwalesi sidakamizwa, ngizizwa ngithuthukile esimweni esijwayelekile emzimbeni. Futhi ngihlala ngilahlekelwa yi-2-3 kg. Ngaso leso sikhathi, intengo iyabiza."
U-Ekaterina, e-Astrakhan: "Umphumela muhle impela. Isimo sesikhumba sesithuthukile futhi saze sancipha kancane. Noma kunjalo, ungasisebenzisi lesi sidakamizwa ngokungalawuleki ukuze unciphise isisindo."
