Amathebulethi i-Acetylsalicylic acid iyikhambi lendawo yonke. Kubhekiswa ezidakamizweni ezingezona ze-steroidal ezilwa nokuvuvukala. Ine-analgesic enhle, i-antipyretic, i-antiplatelet effect.
Igama Lezwe elingafanele
INN: Aspirin.
Amaphilisi ane-analgesic enhle, i-antipyretic, i-antiplatelet effect.
NgesiLatin - Acetylsalicylic acid.
I-ATX
Ikhodi ye-ATX: B01AC06.
Ukwakheka
Amathebulethi aqukethe 250, 100 no-50 mg wekhompiyutha esebenzayo. Izithako ezingeziwe: isitashi samazambane kanye ne-asidi ethile ye-citric.
Amathebhulethi ayindilinga, amhlophe ngombala, ahlanganiswe ngokuhlanganiswa okuhlanganayo.
Umuthi uyatholakala ngesimo sethebhulethi. Amathebhulethi ayindilinga, amhlophe ngombala, ahlanganiswe ngokuhlanganiswa okuhlanganayo. Ngakolunye uhlangothi kukhona umugqa okhethekile wokuhlukanisa. Zibekwa emaphaketheni akhethekile okulimaza amathebulethi ayi-10 lilinye. Amabhola asekhadini lekhadibhodi lama-10 ama-pcs.
Isenzo se-Pharmacological
Ukusebenza kwesenzo kuhlotshaniswa nokuvinjwa komsebenzi we-COX we-enzyme eyinhloko, i-arachidonic acid, ebandakanyeka kumetabolism. Kuyinto eyandulelayo kuma-prostaglandins, adlala indima enkulu ekwehliseni inqubo yokuvuvukala, ama-syndromes obuhlungu nomkhuhlane.
Lapho usemzimbeni, i-Aspirin icishe iphazamise ngokushesha ukwakheka kwama-prostaglandins athile. Kulokhu, izinhlungu ziyamiswa futhi ukuvuvukala kuyancipha. Imithambo yegazi yanda kakhulu, okuholela ekujuleni kokujuluka. Lokhu kuchaza umphumela we-antipyretic womuthi.
I-Aspirin yehlisa ukuzwela kokuphelela kwezinzwa, okunomthelela kumphumela we-analgesic osheshayo.
Izithako ezisebenzayo zisiza ukwehlisa ukuhlangana kweplatelet ne-thrombosis ngenxa yokuvinjwa kokuhlanganiswa kwe-thromboxane emangqamuzaneni egazi ngokwawo. Kukhombisa ukusebenza kahle ekuvinjelweni kwezifo ezahlukahlukene zesistimu yezinhliziyo, ukumalwa kwe-myocardial.
I-Pharmacokinetics
Lapho uthatha amaphilisi ngaphakathi, kufakwa ngokushesha into leyo nto emathunjini amancane nasesiswini. I-Metabolism yenziwa esibindini. Ukuhlushwa kwe-Plasma kuyahluka ngaso sonke isikhathi. Ukubopha ezinhlakeni zamaprotheni kulungile. Kuthululwa emzimbeni wezinso emzimbeni, ikakhulukazi ngesimo se-metabolites eyisisekelo. Isigamu sempilo sicishe sibe yingxenye yehora.
Lapho uthatha amaphilisi ngaphakathi, kufakwa ngokushesha into leyo nto emathunjini amancane nasesiswini.
Yini esiza amaphilisi e-acetylsalicylic acid
Iithebhulethi zinqunyelwe abantu abadala ukwelashwa kanye nokuvinjwa kwezimo ezinjalo ze-pathological:
- isifo samathambo;
- chorea;
- i-pleurisy ne-pneumonia;
- ukuvuvukala kwe-pericardial sac;
- izifo ezihlangene
- ikhanda elibuhlungu nobuhlungu bezinyo;
- imisipha iminyene ngomkhuhlane;
- migraines ephikelelayo;
- ubuhlungu ngesikhathi sokuqala kokuya esikhathini;
- i-osteochondrosis ne-lumbago;
- umkhuhlane kanye nomkhuhlane omkhulu;
- ukuvimbela kokuhlaselwa yisifo senhliziyo nokujuluka kwegazi;
- i-angina pectoris engazinzi;
- isifiso sokuthola ifa ku-thromboembolism kanye ne-thrombophlebitis;
- i-mitral valve prolapse kanye nokunye ukukhubazeka kwenhliziyo;
- i-pulmonary infarction ne-thromboembolism.
Kufanele kukhunjulwe ukuthi i-Aspirin ingumuthi onamandla. Akufanele bavunyelwe ukubaphatha ngaphandle kokuthinta uchwepheshe; ukuzelapha kungakhulisa izimpawu zesifo esikhona.
Contraindication
Kunemikhawulo ethile mayelana nokusetshenziswa kwomuthi:
- i-hemorrhagic vasculitis;
- i-gastritis kanye nesilonda sesisu;
- i-coagulability yegazi elibi;
- ukuntuleka kwe-Vitamin K emzimbeni;
- i-aortic aneurysm;
- hemophilia;
- ukungasebenzi kahle kwe-renal kanye ne-hepatic;
- ukungabekezeleli nokungezwani nama-salicylates;
- umfutho ophikelelayo we-arterial hypertension;
- ingozi yokuthola ukopha esiswini.
Konke lokhu kuphambana kuphelele. Isiguli kufanele sibazi ngaphambi kokuqala ukwelashwa.
Ngokunakekela
Ukuqapha umuthi kufanele uthathwe nge-hangover. Kungcono kuleli cala ukusebenzisa amaphilisi ancibilikayo asebenza ngokugcwala. Kunconywa ukuthi umthamo ubhekwe ngokuqinile ukugwema ukuthuthukiswa kwe-aspirin triad.
Ungawathatha kanjani amaphilisi e-acetylsalicylic acid
Kuphuzwa kuphela ngomlomo ngokudla. Kungcono ukubaphuza ngobisi ukuze unciphise umphumela ocasulayo we-asidi ku-mucosa wesisu.
Mangaki amaphilisi angakwazi
Abantu abadala banqunywa ithebhulethi elilodwa lama-500 mg kabili ngosuku. Inkambo yokwelashwa akufanele idlule izinsuku eziyi-12. Kepha udinga ukuthatha ithebhulethi nsuku zonke ngaphandle kwekhefu.
Ukuvimbela ukukhula kwesifo senhliziyo, kubekwa uhhafu wethebhulethi ngosuku ngenyanga.
Ngoshukela
Ukuqapha kuvumela ukuphuza umuthi wesifo sikashukela. Njengoba kungekho glucose ekwakhiweni, lo muthi awunawo nomthelela ushukela wegazi.
Imiphumela emibi yamacwecwe e-acetylsalicylic acid
Lapho uphuza amaphilisi, kungenzeka ukuthuthukisa imiphumela eminingi emibi ethinta cishe zonke izitho nezinhlaka.
Ngenkathi ukuphuza amaphilisi, isicanucanu kuvame ukwenzeka.
Amapheshana wesisu
Imvamisa kuba ne-nausea kanye nokuhlanza, ubuhlungu besisu nohudo. Mhlawumbe ukwephulwa kwesibindi. Ingozi yokopha evela emgodini wokugaya ukudla, ukuthuthukiswa kwezilonda ezivuvukala nezikhula kalula.
Izitho zeHematopoietic
I-Thrombocytopenia kanye ne-anemia akuvamile ukubonwa. Isikhathi sokuphuma kwegazi siyanda. Kwezinye izimo, ukuthuthukiswa kwe-hemorrhagic syndrome kungenzeka.
Isistimu yezinzwa ephakathi
Uma uphuza amaphilisi isikhathi eside, isiyezi kanye nekhanda elibuhlungu kungenzeka, ngaphezu kwalokho, ukulimala okubukwayo ne-tinnitus.
Kusuka ohlelweni lomchamo
Mhlawumbe ukuthuthukiswa kwesigaba esibi sokuhluleka kwe-renal kanye nokunye ukusebenza kwe-renal okhubazekile, ukubonakala kwe-nephrotic syndrome.
Ukusuka ohlelweni lomchamo, ukuthuthukiswa kwesigaba esibi sokuhluleka kwe-renal kungenzeka.
Allergies
Imiphumela yokungezwani komzimba yenzeka kaningi. Kungaba imivimbo yesikhumba, i-edema kaQuincke, i-bronchospasm enzima.
Imvamisa kukhona ukwanda kwezimpawu zokuhluleka kwenhliziyo kanye neReye syndrome. Mhlawumbe ukwehla kokungazinzi kanye nokubonakala kwezinduna ebusweni nasemhlane. Imaski ekhethekile yobuso izosiza ukubasusa.
Umthelela ekhonweni lokulawula izindlela
Lapho usebenzisa insiza yezokwelapha, kungcono ukuyeka izindlela zokuzishayela nezokuphamba ezidinga ukugxila, ukunakwa, kanye nokusabela okusheshayo.
Imiyalo ekhethekile
Ngokuqapha, amaphilisi anqunyelwa izilonda zokulimala zendlela yokugaya, kanye nangaphambi komlando wesifo somoya (bruschial asthma). Ngokunciphisa ukuphuma kwe-uric acid, i-gout ivame ukukhula.
Sebenzisa ebudaleni
Ekugugeni kusetshenziselwa ukuvimbela kanye nokwelashwa kwe-pathologies yehliziyo.
Isabelo sezingane
Lesi sidakamizwa asinqunyelwe izingane ezingaphansi kweminyaka engu-15. Njengoba ukutheleleka ngegciwane, iReye syndrome ingahle ikhule.
Lesi sidakamizwa asinqunyelwe izingane ezingaphansi kweminyaka engu-15.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukuthatha umuthi kuphikiswe ku-trimesters wesibili nowesithathu wokuzala umntwana. Ukusetshenziswa okungalawulwa kungaholela ekwakhiweni kwe-intrauterine pathologies ye-fetus nokungahambisani kolwelwesi olunzima. Mhlawumbe ukuvalwa ngaphambi kwesikhathi kwe-ductus arteriosus ku-fetus. Awukwazi ukuphuza amaphilisi ngesikhathi sokuqunjelwa. I-acid idlulela ebisini lwebele futhi kungadala ukopha enganeni.
Ukweqisa
Izimpawu ze-overdose zivamile. Lezi yizimpawu ze-dyspeptic. Ezimweni ezibucayi, ukuqwashisa kungakhubazeka, zonke izitho nezinhlelo zihlupheka, kungaba nomthambo. Umthamo obulalayo kubantu abadala ngu-10 g. Uhlelo lwe-hematopoietic nalo luyahlupheka, oluthinta isikhathi sokopha. Ukwelashwa okubonakalayo kwenziwa esibhedlela kuphela.
Ukuxhumana nezinye izidakamizwa
Uma usebenzisa i-Aspirin nezinye izidakamizwa ezilwa nokuvuvukala, ubungozi bokuqhamuka nezinkinga nokuboniswa kwe-overdose kukhuphuka kuphela. Ukuphefumula kwezinso kungaqala ukwanda. Ngokusetshenziswa kanyekanye kwama-antacid, ukufakwa kwe-Aspirin egazini kuncishisiwe.
Kwenqatshelwe ukuthatha umuthi ngama-anticoagulants. Ama-diuretics ehlisa umphumela wokwelapha. U-Ethanol wandisa izimpawu zokudakwa. Ama-Barbiturates, izithasiselo zokudla ezahlukahlukene kanye ne-metoprolol anciphisa kakhulu umphumela we-aspirin. Ngokuhlushwa okwanele kweDigogsin, lapho kuhlanganiswa ne-acetylsalicylic acid, okuqukethwe kwayo emzimbeni kuyanda.
Kungenziwa ngokuhlanganiswa ne-caffeine ukwandisa ukumunca umuthi.
Ingahlanganiswa ne-caffeine neparacetamol. I-Caffeine ikhulisa ukumuncwa kwe-Aspirin kanye ne-bioavailability yayo.
Ukuhambisana notshwala
Ungathathi amaphilisi notshwala. Umphumela ohlelweni lwezinzwa ukhuphuka kakhulu, izimpawu zokudakwa ziyanda. Umphumela we-asidi ohlelweni lokugaya ukudla uyanda.
Ama-Analog
Kunezindlela eziningi:
- Aspirin Cardio;
- Aspicore
- Paracetamol;
- I-Cardiomagnyl;
- I-Plidol;
- I-Polokard;
- I-Thrombo ACC.
Ukuzikhethela komuthi okumelwe ungene esikhundleni kufanele kwenziwe ngudokotela ngokuya ngosizi lwalesi sifo.
I-Acetylsalicylic acid ingafakwa esikhundleni se-Asperin Cardio.
Imibandela yekhefu lekhemisi
Imithi ingathengwa kunoma iyiphi ikhemisi ngaphandle kwencwadi kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela
Amaphilisi atholakala ngokukhululeka. Bakhishwa ngaphandle kwencwadi kadokotela.
Intengo
Izindleko ziqala kusuka kuma-ruble ayi-7.
Izimo zokugcina zomuthi
Kuyadingeka ukugcina amaphilisi endaweni evikelwe ezinganeni. Kuyinto engathandeki ukuvumela ukukhanya kwelanga ngqo kubo.
Isikhathi sokuphelelwa yisikhathi
Isikhathi sokubeka yiminyaka engu-4 kusukela esikhathini sokukhiqizwa.
Umkhiqizi
I-FP OBOLENSKO JSC (Russia).
Ukubuyekezwa
UVictoria, oneminyaka engama-32, eMoscow: "Ngihlala ngigcina ama-aspirin ekhabethe lezokwelapha. Kuyasiza ukwehlisa izinga lokushisa impela. Ngemuva kwemizuzu engu-30, umuthi uqala ukusebenza. Umuthi awugcini nje ngokunciphisa umkhuhlane, kodwa futhi usebenza njenge-analgesic - ukhulula izinhlungu ezihlangene, ukuqaqamba komzimba. Ngiyawusebenzisa. "njengoba kubekiwe kuphela, ukuze kungabangeli ukopha. Kuyafaneleka ukuthi umuthi ungabizi, ungathengwa kunoma iyiphi ikhemisi."
USvetlana, oneminyaka engama-25, eSt. Petersburg: "Ngisebenzisa imaski yobuso. Nginenkinga yesikhumba, umqubuko omningi kanye nezinduna, ngakho-ke ngazama imishanguzo eminingi yokwelashwa .. Ngemuva kwamamaski ama-2, ukuvuvukala kwaqala ukuncipha, isikhumba saqala ukuhlanza. Ngemuva kwe-2 Ngilaphe ngokuphelele inyanga eyodwa. Yize umqubuko uvelile, ubungekho kangako ngosayizi. "
UMargarita, oneminyaka engama-44, uSaratov: "Umama uyagula unesifo sikashukela. Ngaphezu kwalokho, inhliziyo yakhe ibuthakathaka nemithambo yegazi ihlupheka. Ngakho-ke, amakhaza ahlala enenkinga yokuthi imiphi imithi okufanele ayisebenzise. Udokotela wamncoma u-Aspirin. Awunawo ushukela futhi awukhulisi ushukela wegazi "Ngiwunikeze umgomo ngqo futhi ngaveza ukuthi kufanele uphuzwe kuphela ngokudla."