Uyini umehluko phakathi kweSumamed ne-Amoxiclav?

Ama-penicillin ne-macrolide ama-antiam umuthi asebenzayo futhi aphephile anqunyelwe izifo ezingamagciwane zesikhumba, ipheshana lesisu, amasistimu okuphefumula nawezakhi zofuzo, izicubu ezithambile, njll. Ngokuya izinkomba nokuzwela ngakunye kwezidakamizwa, odokotela bezingane nodokotela bezokwelapha batusa ukuthatha i-Sumamed noma i-Amoxiclav, kanye Ukuqondanisa kwalezi zimali.

Isimo seSumamed

Into esebenzayo yeSumamed yi-azithromycin. Isebenza ngempumelelo kuma-gram-positive (staphylococci, streptococci), gram-negative (hemophilic bacillus, moraxella, gonococci), anaerobic (clostridia, porphyromonads) kanye nezinye izinto ezincane. Impahla ebalulekile ye-azithromycin ukusebenza kwayo ngokulwa namagciwane we-chlamydia, mycoplasmosis kanye ne-borreliosis (isifo seLyme).

I-Sumamed noma i-Amoxiclav izidakamizwa ezisebenzayo neziphephile ezibekelwe izifo zamagciwane.

Ukusetshenziswa kweSumamed kukhonjisiwe kuma-pathologies alandelayo:

• ukutheleleka kwamagciwane okwenziwe endaweni yokuphefumula (i-pharyngitis, i-sinusitis, i-sinusitis, imithombo yezindaba ye-otitis, i-pneumonia etholwa ngumphakathi, i-bronchitis enezifo ezingelaphekiyo, i-tracheitis, njll.);
• izifo zesikhumba nezicubu ezithambile (impetigo, izinduna ezinzima, ama-erysipelas) noma ukutheleleka kwegciwane lesibili nge-dermatoses;
• isigaba sokuqala se-borreliosis.

Futhi, umuthi ubekelwe ukwelashwa kwe-cervicitis, i-urethritis kanye nokunye ukuvuvukala kohlelo lwe-urogenital olubangelwa ama-STI, kanye nokuvimbela i-endocarditis ethelelekile kanye ne-mycobacteriosis.

Umuthi iSumamed ubekelwe ukwelashwa kokuvuvukala kohlelo lwezitho zofuzo.

I-Sumamed itholakala ngezindlela ezahlukahlukene:

1. Amathebhulethi Omlomo Oqaqa. Umthamo we-antibiotic ezisezibhebheni ungaba ngu-125 mg, 250 mg, 500 mg noma 1 g.
2. Amakhandlela I-1 capsule ye-gelatin iqukethe u-250 mg we-azithromycin.
3. Amandla wokumiswa. Umthamo we-azithromycin ekumisweni kweSumamed ngu-100 mg ku-5 ml wesidakamizwa, ekumisweni kweSumamed Forte - 200 mg / 5 ml. Umuthi osezingeni eliphansi usetshenziselwa ukwelapha izingane ezisanda kuzalwa. Le fomu yemithamo yenzelwe izingane, ngakho-ke, i-powder iqukethe ukunambitheka (banana, sitrobheli, okusajingijolo, i-cherry noma i-vanilla).
4. I-Powder yomjovo. Ibhodlela elilodwa lomuthi liqukethe ama-500 mg we-antibiotic.

Ezinye izinhlobo zezidakamizwa ziqukethe i-aspartame noshukela. Lokhu kufanele kubhekwe lapho kukhona i-phenylketonuria noma isifo sikashukela esigulini.

Ukuxhumana kokusetshenziswa kweSumamed yilezi zimo ezilandelayo:

• i-hypersensitivity ku-azithromycin, amanye ama-macrolide nama-ketolide, izithako ezisizayo;
• ukuthatha izidakamizwa ze-ergotamine kanye ne-dihydroergotamine;
• ukwephulwa okukhulu kwesibindi nezinso (isilinganiso sokuhlunga kwe-glomerular esingaphansi kwama-40 ml / min);
• isisindo esiphansi nobudala besiguli (kuze kube yiminyaka emi-3 yamathebulethi ahlakazekile, kuze kufike ku-5 kg ​​wesisindo somzimba ngokumiswa).

Nge-arrhythmias noma ukuhluleka kwenhliziyo, isikhathi esandisiwe se-QT, i-bradycardia, isibindi kanye ne-pathologies yezinso, ukuthatha izidakamizwa eziningi (iWarfarin, i-Digoxin, izidakamizwa ze-antiarrhythmic, njll.) I-Sumamed isetshenziswa ngokuqapha.

Ukuvumelanisa ukusetshenziswa kweSumamed yi-hypersensitivity to azithromycin.

Ungasebenzisi i-Sumamed ekulimazeni okukhulu kwezinso.

I-Sumamed isetshenziswa ngokuqapha ekwehlulekeni kwenhliziyo.

Izici ze-Amoxiclav

I-Amoxiclav iqukethe izinto ezimbili ezisebenzayo: i-antibiotic amooticillin ne-clavulanic acid. I-Amoxicillin ingeyeqembu lama-penicillin angama-semisynthetic futhi inomphumela we-bactericidal kuma-pathogen alandelayo:

• amagciwane we-aerobic we-gram-positive (streptococci, pneumococci kanye ne-staphylococci);
• amagciwane angasebenzisi gram (i-Klebsiella, i-Escherichia coli ne-Haemophilus influenzae, Enterococci, Moraxella).

Ingxenye yesibili yesidakamizwa, i-clavulanic acid, yenza ukuthi i-beta-lactamases ikhiqizwe ngamagciwane amelana ne-amoxicillin. Lokhu kuvikela indandatho ye-beta-lactam elwa namagciwane ekulweni ukubola futhi kulondoloze ukusebenza komuthi.

Izinkomba zokusetshenziswa kwe-Amoxiclav yilezi zifo ezilandelayo:

• ukuvuvukala kwamagciwane emgudwini wokuphefumula;
• ukuvuvukala kwe-urethra, isinye, izinso;
• i-gynecological pathologies;
• cholecystitis, ulcer esiswini (ukuqedwa kwe-Helicobacter pylori colonies), cholangitis;
• izifo zesikhumba, ithambo kanye nezicubu ezithintekayo;
• Ama-STI (i-gonorrhea, chancre), izinqubo zokuvuvukala ngaphakathi kwamathumbu, ukuvuselelwa ngemuva kokuhlinzwa.

I-Amoxiclav isetshenziswa kaningi kudokotela wamazinyo.

I-Amoxiclav isetshenziswa kaningi kudokotela wamazinyo ukwelapha nokuvikela ukuthuthukiswa kwezinkinga zesifo se-gum bacterium (ngokwesibonelo, i-endocarditis).

Uhlobo lomuthi olunconyiwe lungahluka ngokuya ngezinkomba zokwelashwa kanye nobudala isiguli. I-Amoxiclav iyatholakala ngalezi zinhlobo ezilandelayo zemithi:

1. Amaphilisi Umthamo wengxenye ye-antibacterial kuthebhulethi eyi-1 ungaba ngu-250 mg, 500 mg noma we-875 mg. Inani le-beta-lactamase inhibitor ngeyunithi ngayinye yezidakamizwa alishintshiwe - 125 mg.
2. Amathebulethi ahlakazekile. Umthamo we-amooticillin / clavulanic acid ngu-500 mg / 125 mg no-875 mg / 125 mg.
3. Powder wokwenza ukumiswa. Umthamo we-antibiotic ne-beta-lactamase inhibitor ekumisweni okungama-5 ml ungaba ngu-125 mg no-31.25 mg, 250 mg no-62.5 mg no-400 mg no-57 mg, ngokulandelana.
4. I-Powder yokwenza ikhambi lomjovo. Umthamo we-amooticillin / clavulanic acid ngu 500 mg / 100 mg, 1000 mg / 200 mg.

Ukusetshenziswa kwe-Amoxiclav kufakwe ku-pathologies efana ne:

• I-hypersensitivity kuma-penicillin, i-cephalosporins, i-monobactam, umlando we-carbapenems, ukungezwani komzimba kwizitho ezisizayo zomuthi (kufaka phakathi i-phenylketonuria);
• ukuphazamiseka kwesibindi, okucasulwa ukusetshenziswa kwe-amoxicillin noma i-clavulanate;
• i-lymphocytic leukemia;
• i-monocytic tonillitis (mononucleosis).

Ukusetshenziswa kwe-Amoxiclav kufakwe kuphikisana nesibindi.

Kuphikisiwe ukusebenzisa ifomu elihlakazekile le-Amoxiclav elinesisindo somzimba esifinyelela kuma-40 kg, kuze kube yiminyaka eyi-12, ngesilinganiso sokuhlunga kwe-glomerular esingaphansi kwama-30 ml / min.

Kwezifo zepheshana lesisu, elicasulwa ama-beta-lactam antibiotic, ukwehluleka kwezinso noma kwesibindi, ukukhulelwa, ukuncelisa kanye nokuphathwa kanyekanye nama-anticoagulants (kufaka phakathi i-warfarin), i-Amoxiclav inqunywe ngokuqapha.

Ukuqhathanisa kweSumamed ne-Amoxiclav

I-Amoxiclav ne-Sumamed zisetshenziselwa izinkomba ezifanayo, ngakho-ke, ekukhetheni okuqondile kwemithi, ukufana nokuhluka kwemithi kufanele kucaciswe.

Ukunquma umuthi olwa namagciwane kufanele kwenziwe kuphela ngudokotela ohambelayo. Umsebenzi wesiguli ukukhombisa umlando wokuphendula komzimba, uhlu lwemithi, izimo zezempilo ezikhethekile kanye ne-pathologies engamahlalakhona.

Ukufana

I-Amoxiclav ne-Sumamed banezici ezimbalwa ezivamile:

• uhla olubanzi lwesenzo se-antibacterial;
• amathuba okufaka esikhundleni se-antibiotic elilodwa ngesinye uzwela komuntu komunye umuthi;
• ukuphepha kokwelashwa nazo zombili izidakamizwa ezinganeni nakubantu abadala;
• Indinganiso yokuphepha ye-FDA - B (ukusetshenziswa ngesikhathi sokukhulelwa kuvunyelwe uma izinzuzo zowesifazane okhulelwe ziphakeme kunobungozi bokulimala kuzingane);
• kungenzeka kokuthonya ukuqoqwa kokunakwa ngenxa yemiphumela emibi evela ohlelweni lwezinzwa oluphakathi.

Uyini umehluko

Yize kukhona ubukhona bezimpawu ezifanayo, umehluko phakathi kwama-antibiotic amabili ubalulekile futhi uboniswa kokulandelayo:

1. Indlela yokusebenza. I-Amoxicillin (Amoxiclav) ibhubhisa udonga lweseli lwamagciwane, ikhombisa umphumela we-bactericidal, kanti i-azithromycin (Sumamed) ivimbela ukwakheka kwamaprotheni kuma-ribosomes futhi inciphise ukukhula kwekoloni lamagciwane.
2. Isikhathi nobuningi bokuthatha umuthi nge-pathology efanayo. I-Azithromycin iqongelela kahle izicubu, ngakho-ke iSumamed ithathwa isikhathi esingu-1 ngosuku ngezinsuku ezi-3 (uma kunesidingo, ukwelashwa kuyaqhubeka). I-Amoxiclav kufanele idakwe izikhathi ezingama-2-3 ngosuku izinsuku ezingama-5-14. Umthamo wokwelapha we-amooticillin ne-azithromycin ngenkambo ngayinye yokwelashwa ungahluka ngezikhathi ezingama-2-3.
3. Ukuphepha kweziguli. Naphezu kwesigaba esisodwa se-FDA, i-Amoxiclav ibhekwa njengephephe kakhulu ngesikhathi sokukhulelwa futhi, ngokungafani neSumamed, isetshenziselwa i-lactation.
4. Imvamisa yokusabela okuphambene. Imiphumela emibi ibonwa kaningi ngokwelashwa kweSumamed.

Yikuphi okushibhile

Ngokwesikhathi sokwelashwa esijwayelekile, izindleko zokwelashwa nge-Amoxiclav ne-Sumamed cishe zilingana. Kwezifo ezinzima, ezibandakanya ukwelashwa isikhathi eside nge-amoxicillin kanye nohlu lomuthi izikhathi ezimbili ngosuku, ukwelashwa ngemithi elwa nama-macrolide kushibhile, ngoba Ama-Sumamed kumele athathwe isikhathi esingu-1 ngosuku izinsuku ezintathu.

Ngokwesikhathi sokwelashwa esijwayelekile, izindleko zokwelashwa nge-Amoxiclav ne-Sumamed cishe zilingana.

Yikuphi okungcono: ISumamed noma i-Amoxiclav?

I-Amoxiclav nezimpawu zayo yizidakamizwa ezikhethiwe zezifo zohlelo lokuphefumula, ipheshana lomchamo nezinye izitho zangaphakathi.

I-Sumamed ikuvumela ukuthi ungene esikhundleni se-Amoxiclav ekungeneni kwe-pathogen ye-atypical, ukuvuvukala kohlelo lwezakhi zofuzo olubangelwa ama-STI, ukungezwani nezidakamizwa ze-beta-lactam antibacterial, kanye ne-penicillin therapy ukungasebenzi kahle.

Okwezingane

ISumamed ne-Amoxiclav ziphephile ezinganeni, kepha i-amoxicillin isetshenziswa kaningi kwizingane.

Inzuzo yokulungiselela kwe-macrolide ukutheleleka okujwayelekile kwengane yithuba lokuthola umthamo owodwa womthamo omkhulu we-antibiotic ku-otitis middle otitis media yemvelaphi yamagciwane.

ISumamed ne-Amoxiclav ziphephile ezinganeni, kepha i-amoxicillin isetshenziswa kaningi kwizingane.

Ukubuyekezwa kodokotela

I-Amosova O.P., udokotela wezifo zabesifazane, uKrasnodar

I-Sumamed yi-ejenti enhle ye-antibacterial. Ngivame ukusinikeza iziguli ukwelashwa kwezifo zangasese (chlamydia, urea kanye ne-mycoplasmosis). Umuthi ubekezelelwa kalula yiziguli futhi unendlela elula yomthamo.

Uma inani lentengo lomuthi liphezulu kakhulu, lingathathelwa indawo i-analogue yasekhaya (Azithromycin).

UChernikov S.N., udokotela wezingane, uVoronezh

I-Amoxiclav iyi-antibiotic ejwayelekile yezinqubo zokuvuvukala zamapheshana okuphefumula. Ngokuya ngomthamo, ungakhetha ifomu lethebhulethi lomuthi noma ukumiswa.

Ezimweni eziningi, i-Amoxiclav ibekezelelwa kahle, kepha kwezinye izimo, imithamo emikhulu yomuthi nokwelashwa okuqhubeka isikhathi eside ibangela isifo sohudo nobuhlungu besisu.

Ukubuyekezwa kweziguli ku-Sumamed ne-Amoxiclav

UCatherine, oneminyaka engama-25, uVeliky Novgorod

Ngobusika bokugcina, wagula kakhulu, waba nomkhuhlane ophakeme ngokukhwehlela kanye nekhala. Udokotela wahlonza i-tracheitis futhi wanquma i-Amoxiclav. Ngaphuza amaphilisi umthamo ophelele kabili ngosuku, ngokushesha ngemuva kokudla. Basize ngokushesha, abazibonanga izinkinga ngesisu nangamathumbu. Okuwukuphela kwesimo esibi izindleko eziphakeme zomuthi.

UVeronika, oneminyaka engama-28, uSamara

I-Sumamed isidakamizwa esihle kakhulu, kepha kufanele sithathwe kuphela njengezinyathelo sokugcina, lapho ezinye izidakamizwa zingasizi. Udokotela unikeze lo muthi indodana yakhe ngenkathi izidakamizwa zemithi zingasebenzi. ISumamed yabe isisiza ngokushesha futhi isikhathi eside.

Ngesikhathi sokulashwa, kufanele uphuze ama-probiotic amathumbu bese ucabanga nge-contraindication.