Ama-analgesics anomphumela wokwelapha oshiwo ezimeni eziningi asetshenziselwa ukuqeda izinhlungu ezigulini ezinomdlavuza. Umuthi ubangela ukusabela okuningi okungathandeki.
Igama Lezwe elingafanele
Imvamisa udokotela ubhala umuthi womuthi ngesiLatini. Phentanylum (fentanyl) - igama lento esebenzayo yesidakamizwa.
IDurogezik ngenye yezidakamizwa ezinemiphumela ye-analgesic and sedative.
I-ATX
I-N02AB03 - ikhodi yokuhlukaniswa kwamakhemikhali-okwelashwa ngamakhemikhali.
Khipha amafomu nokwakheka
Umuthi wenziwa ngendlela yesibaya esingunxande nge-gel esobala equkethwe kuso.
Ukwakheka kwalesi sidakamizwa kufaka phakathi i-fentanyl. Inani lokukhishwa kwento ye-psychotropic ngu-25 μg / h no-50 μg / h.
Umuthi wenziwa ngendlela yesibaya esingunxande nge-gel esobala equkethwe kuso.
Isenzo se-Pharmacological
Kunezici eziningi ezinjalo:
- IDurogezik ngenye yezidakamizwa ezinemiphumela ye-analgesic and sedative. Ingxenye esebenzayo ye-analgesic iphazamisa ukudluliswa kokufakwa kwezinzwa kusuka kuma-receptors kuye ku-cortex yecerebral.
- Ithuluzi libonisa ukucaphuka kwe-anal sphincter nemisipha ebushelelezi yesinye.
- Umuthi ubanga i-euphoria futhi ukhuthaza ukuqala kokulala.
- Umphumela we-analgesic uhlala okungenani amahora angama-72.
I-Pharmacokinetics
Umuthi osebenzayo uthululwa esibindini, kanti imikhiqizo ebolayo ye-fentanyl iyadedelwa kanye nomchamo nenani elincane elinama-ndun.
Ukuphakanyiswa okuphezulu kakhulu kwengxenye esebenzayo kubonwa ngeplasma yegazi phakathi nosuku.
Izinkomba zokusetshenziswa
Isidakamizwa sisetshenziswa lapho kubonakaliswa izimpawu ezilandelayo zokubonisa:
- Ubuhlungu obukhulu lapho kunesimila somdlavuza.
- Ubuhlungu be-Neuropathic obuvela ku-multiple sclerosis kanye ne-diabetesic polyneuropathy (ushintsho oluwohloka kwimicu yezinzwa).
- Ubuhlungu be-phantom ezifweni zohlelo lwe-musculoskeletal.
Contraindication
Umuthi awukwazi ukusetshenziswa kumacala alandelayo:
- Ngokubekezelela ngakunye kwesithako esisebenzayo.
- Iziguli ezingaphansi kweminyaka engu-18 ubudala.
- Ngokungasebenzi kwesikhungo sokuphefumula.
- Uma kwenzeka kubuhlungu obukhulu esikhathini se-postoperative.
- Ngesikhathi sokukhulelwa kunoma iyiphi i-trimester nangesikhathi uncelisa ibele.
Awukwazi ukusebenzisa umuthi lapho ukhona khona izilonda ezincane esikhunjeni.
Ngokunakekela
Akunconyelwe ukusebenzisa i-transdermal patch emacaleni amaningi anjalo:
- Ebusweni besifo esingelapheki.
- Uma kwenzeka kwanda ingcindezi ye-intracranial.
- Ngokuncipha kwengcindezi yegazi.
- Ngokuhluleka kwe-renal noma i-hepatic dysfunction.
I-Dyurogezik isetshenziselwa izinhlungu ze-neuropathic ezivela ngenxa yesifo sokuqina kanye nesifo sikashukela polyneuropathy (ushintsho oluwohlokayo emithanjeni yezinzwa).
Umuthi ubekelwe izinhlungu ezinzima lapho kunesimila somdlavuza.
I-Durogezik iyanconywa uma kwenzeka kubuhlungu be-phantom ezifweni zohlelo lwe-musculoskeletal system.
I-Durogezik ayinconywa ukuthi isetshenziswe phambi kwesifo samaphaphu esingamahlalakhona.
Isichibi asisetshenziswanga uma kucindezela ingcindezi ye-intracranial.
IDurogezik ayinconywa ukwehlisa umfutho wegazi.
Ungayithatha kanjani iDurogezik
Kubalulekile ukulandela imiyalo yokusebenzisa umkhiqizo ukufezekisa amandla amahle ekususeni kwezimpawu.
Ezimweni eziningi, ukukhethwa komthamo we-fentanyl kuya ngesilinganiso esinconywe ngomlomo se-opioid esivele sinconywa.
Ukuthinta kuphi
Umkhiqizo kumele ufakwe endaweni eyomile yesikhumba sesiqu noma amahlombe. Kuqala kubalulekile ukushefa izinwele esikhunjeni. Awukwazi ukusebenzisa izimonyo ezinhlobonhlobo zokunakekela umzimba ngaphambi kokusebenzisa isihlwathi ukugwema ukusabela komzimba noma ukunciphisa ukusebenza komphumela wokwelapha umuthi.
Akunconywa ukunamathisela isichibi endaweni efanayo yesikhumba, ngaphandle kokubheka isikhathi sokuphumula (azikho izinsuku ezingama-5-7).
Isikhathi sesenzo
Umuthi unomphumela we-analgesic izinsuku ezintathu.
Ngoshukela
Udokotela unquma umthamo odingekayo wezinto ezisebenzayo, unikezwe ubunzima bendawo yesifo sikashukela se-polyneuropathy nezimpawu zomzimba.
Imiphumela emibi Durogezika
Kunemiphumela emibi ehlukahlukene ekwelashweni kweziguli ezine-Durogesic.
Isistimu yezinzwa ephakathi
Ukudana komoya kukhula njalo. Insomnia iyisici.
Umkhiqizo kumele ufakwe endaweni eyomile yesikhumba sesiqu noma amahlombe.
Kusuka ohlelweni lokuphefumula
Ukuphazamiseka okungenzeka kwamaphaphu. Ezimweni ezingavamile, ukuphefumula komoya kwenzeka.
Amapheshana wesisu
Ukusikhulula kuvame ukubonwa ezigulini, kepha isifo se-stool akuvamile ukwenzeka.
Allergies
Ukuqhuma kwesikhumba okuhambisana nokulunywa yisici.
Umthelela ekhonweni lokulawula izindlela
Kuyadingeka ukuthi uqaphele ezigulini ezinomsebenzi wobungcweti ohambisana nokuphathwa kwezindlela eziyinkimbinkimbi nokwanda kokunakwa.
Imiyalo ekhethekile
Kubalulekile ukucabanga ngezici eziningi lapho usebenzisa lo muthi ukuze uvikele ukuwohloka.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukusetshenziswa kwesichibi kuphikisiwe kwabesifazane abakhulelwe. Ukusebenzisa umkhiqizo ngesikhathi sokuncelisa kungaholela ekuvimbeleni umsebenzi wokuphefumula wengane.
Ukusetshenziswa kwesichibi kuphikisiwe kwabesifazane abakhulelwe.
Ukunquma i-Durogesic ezinganeni
Musa ukusebenzisa isichibi ngaphambi kokufika eminyakeni yobudala.
Sebenzisa ebudaleni
Ezigulini ezineminyaka engaphezu kwengama-65 ubudala, i-hypersensitivity engxenyeni esebenzayo yomuthi iyabonakala, futhi ukugcotshwa kwengxenye esebenzayo esegazini legazi nakho kuyakhuphuka.
Isicelo sokusebenza kokulimala kwezinso
Ngokuqapha, isidakamizwa sibekelwa ukwehluleka kwezinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Kunconywa umthamo omncane wefentanyl lapho kutholakala ukungasebenzi kahle kwe-hepatic.
Ukweqisa kwe-Durogesic
Ngokwenyuka komthamo otuswe ngudokotela, kukhona ukwehla komfutho wegazi kanye ne-apnea (ukuboshwa kokuphefumula).
Ukuxhumana nezinye izidakamizwa
Kubalulekile ukucubungula okulandelayo:
- Ngokuphathwa kanyekanye komlomo kwe-opioid analgesics (Codeine nePetidine), ubungozi bokwehla kwegazi luyanda.
- Uma izidakamizwa ze-antihypertensive zithathwa ngokufana ne-Durogesic, ukwanda komphumela wokwelapha wokugcina kuyabonakala.
- Ukusebenza komphumela we-analgesic Buprenorphine kuyancipha ngenkathi ukusetshenziswa kwe-Durogesic.
Ukuhambisana notshwala
Ukuphuza utshwala ngesikhathi sokwelashwa kwe-opioid akunconywa.
Ukuphuza utshwala ngesikhathi sokwelashwa kwe-opioid akunconywa.
Ama-Analog
IFentadol Matrix neFendivia ziqukethe i-fentanyl.
Imibandela yekhefu lekhemisi
Imithi ayikwazi ukuthengwa emakhemisi eRussia.
Ngingakwazi ukuthenga ngaphandle kadokotela
Ithuluzi lingathengwa kuphela ngokuya ngemithi emakhemisi enamathiselwe ezikhungweni zezempilo.
Malini
Intengo yesidakamizwa okungenani ama-ruble ayi-6,000.
Izimo zokugcina zomuthi
Gcina umkhiqizo endaweni yokushisa yasekamelweni endaweni evikelekile elangeni eliqondile. Kubalulekile ukukhawulela ukufinyelela kwezingane emithini.
Isikhathi sokuphelelwa yisikhathi
I-patch igcina izindawo zayo zokuphilisa iminyaka engu-2 kusukela ngosuku lokukhiqizwa.
Umkhiqizi
Umuthi lo ukhiqizwa yinkampani yaseBelgian uJanssen Pharmaceutica N.V.
Umuthi lo ukhiqizwa yinkampani yaseBelgian uJanssen Pharmaceutica N.V.
Ukubuyekezwa mayelana Durogezik
UKaterina, oneminyaka engama-34, eMoscow
Sekuphele iminyaka eyi-10 ngisebenza njengodokotela. Kwi-oncology, i-Durogesic ijwayelekile, ikakhulukazi uma kukhulunywa ngokuhlaselwa kobuhlungu obukhulu isiguli esingakwazi ukuma. Ngokuvamile okuhlangenwe nakho kwezokwelashwa ngokuvela kokuhlanza ezigulini ezine-hypotension ye-arterial. Ngangiqiniseka ukuthi abantu abathathe iMorphine phambilini kungenzeka maningi ukuthi baphendule kabi lapho besebenzisa isichibi.
U-Olga, oneminyaka engama-40 ubudala, eSt
Indodana yasebenzisa umuthi ukunciphisa izinhlungu esigabeni sesithathu sokukhula kwesimila esibuhlungu. Umuthi waba nemiphumela emihle. Kepha ngokuqhubeka kwesikhathi, kwavela ukuxhomekeka kulokhu ku-analgesic, okwakhulisa ukwanda kwesimo.
UMikhail, oneminyaka engama-51, u-Omsk
Kamuva usebenzise lesi sichibi. Udokotela ubeke lo muthi lapho ethola isifo sikashukela se-polyneuropathy. Ubuhlungu bayekile ukukhathaza amahora angama-5 ngemuva kokufaka ushukela umkhiqizo. Kepha kwavela ukuqubuka endaweni yokufaka isicelo, okuye kwabangela ukulunywa kakhulu. Ama-antihistamines awakwazanga ukusetshenziswa. Kepha ngangigculisekile ngomphumela wokwelashwa, ngoba manje ngilala ebusuku, angihlushwa yizinhlungu. Ngincoma lesi sidakamizwa kuwo wonke umuntu.
