Kwezinye iziguli, i-mancitus ye-pancreatogenic sikhula ngokulwa nesizinda se-pancreatic pathology. Lolu hlobo lwesifo sikashukela alusebenzi kuhlobo lokuqala (T1DM) noma kolwesibili (T2DM). Ngokusho kochwepheshe abaningi, isifo sikashukela se-pancreatogenic luhlobo lwesithathu sikashukela, olunezimpawu ezibonakalayo nezici zenkambo.
Indlela yokuthuthukisa
Ama-pancreas aqukethe izicubu ze-exocrine ne-endocrine. Nge-pancreatitis, phazamisa ushintsho olonakalisayo futhi oluwohlokayo izicubu ze-acinar, kulandelwa ukuqalwa kwe-acini, isakhi esiyinhloko sengxenye ye-exocrine ye-gland.
Ushintsho olunjalo lungangeza naseziqhingini zeLangerhans (amayunithi wesakhiwo sengxenye ye-pancreas), umsebenzi okuwukukhiqizwa kwe-insulin. Ngenxa yalokho, umsebenzi we-endocrine pancreas apparatus uyaphazamiseka, okuholela ekubukekeni kwe-pancreatogenicabetes mellitus.
Isifo sikashukela sohlobo 3 sinezici ezithile:
Iziguli zivame ukuba nomzimba ojwayelekile;- Akukho kusengaphambili kofuzo;
- Amandla okuthuthukisa i-hypoglycemia;
- Iziguli zivame ukutholakala nezifo zesikhumba;
- Isidingo esiphansi sokwelashwa kwe-insulin;
- Ezigulini, i-choleric temperament predominates;
- Ukubonakaliswa kwesikhashana kwezimpawu (ukubonakaliswa). Izimpawu zokukhohlisa kwalesi sifo zizwakala emuva kweminyaka engama-5-7 kusukela ekuqaleni kwalesi sifo esiyisisekelo.
Iziguli zivame ukuba nomzimba ojwayelekile;Ngokujwayelekile kunesifo sikashukela esivamile, i-macroangiopathy, i-microangiopathy, ne-ketoacidosis.
Izizathu zokubukeka
Imbangela enkulu yesifo sikashukela sohlobo 3 i-pancreatitis. Kepha kunezinye izinto ezidonsela phambili ukukhula kwalesi sifo.
Lokhu kufaka phakathi:
- Ukulimala lapho ubuqotho be-pancreas buchaphazeleka khona;
- Ukungenelela kokuhlinzwa (i-pancreatoduodenectomy, i-pancreatojejunostomy ende, i-pancreatectomy,
- Resection resen);
- Umuthi wesikhathi eside (ukusetshenziswa kwe-corticosteroid);
- Ezinye izifo ze-pancreatic, ezinjengomdlavuza, i-pancreatic necrosis, i-pancreatopathy;
- I-cystic fibrosis;
- I-Hemochromatosis
Bandisa amathuba okuba nesifo sikashukela sohlobo 3:
- Ukukhuluphala ngokweqile Isisindo esengeziwe sandisa inkambo ye-pancreatitis futhi sandisa ubungozi bokuthola ubunzima baso. Ezigulini ezinokukhuluphala, ukumelana nezicubu (ukumelana) ne-insulin kuvame kakhulu, okwandisa ingozi yesifo sikashukela.
- Hyperlipidemia. Izinga elikhulayo lama-lipid egazini lomuntu liphazamisa ukuhamba kwegazi, ngenxa yalokho amaseli we-pancreatic angatholi inani elifanelekile lezakhamzimba nokuqhuma kokuvuvukala.
- Utshwala Ngokuphuza okuhleliwe, izinga lokuthuthuka kokuntuleka kwe-exocrine gland liphezulu kakhulu.
ISymbomatology
Izimpawu zesifo sikashukela se-pancreatogenic:
- Umuzwa oqhubekayo wendlala;
- I-Polyuria
- I-Polydipsia;
- Kwehlisiwe ithoni yemisipha;
- Ubuthakathaka
- Umjuluko obandayo;
- Ukuthuthumela komzimba wonke;
- Isasasa elingokomzwelo.
Nge-pancreatogenic sikashukela mellitus, izindonga zamasipha ziba mncane, ukuqina kwazo kuyanda, okubonakala ngaphandle njengokulimaza nokudumba.
Ukwelashwa
Umuthi osemthethweni awuboni isifo sikashukela sohlobo 3, futhi ekuxilongeni leso sifo kuyaqabukela. Ngenxa yalokhu, ukwelashwa okungalungile kunqunyelwe okunganikeli umphumela oyifunayo.
Iqiniso ukuthi ngesifo sikashukela se-pancreatogenic, ngokungafani nesifo sikashukela sezinhlobo ezimbili zokuqala, kuyadingeka ukuthonya hhayi i-hyperglycemia kuphela, kodwa futhi nesifo esingaphansi (i-pathology of pancreas).
Ukwelashwa kwesifo sikashukela sohlobo 3 kufaka:
- Ukudla
- Ukwelashwa kwezidakamizwa;
- Imijovo ye-Insulin;
- Ukungenelela kokuhlinzwa.
Ukudla
Ukudla kwe-pancreatogenicabetes mellitus kuqukethe ukulungiswa kokuntuleka kwamaprotheni-amandla, kufaka phakathi i-hypovitaminosis. Kuyadingeka ukukhipha ukudla okunamafutha, okunezipayisi kanye nokuthosiwe, ama-carbohydrate alula (isinkwa, ibhotela, amaswidi).
Ukudla okuphuziwe kufanele kugcwalise ngokuphelele imithombo yamavithamini namaminerali omzimba. Kuyadingeka nokuthi ubushiye ngokuphelele utshwala.
Ukwelashwa kwezidakamizwa
Ukwelashwa ngezidakamizwa kubandakanya ukufaka izidakamizwa:
- Enzymatic;
Ukunciphisa ushukela;- AmaPainkiller;
- Ukunikeza ukubuyiselwa kwemali esele ye-electrolyte;
- Vitamin complexes.
Ukunciphisa ushukela;Ukwelashwa ngamalungiselelo we-enzyme kuyindlela eyengeziwe (enhle) yokwelapha lesi sifo. Amalungiselelo ama-enzyme asetshenziselwa ukwelapha uhlobo lwe-3 yesifo sikashukela kufanele aqukethe i-amylase, i-peptidase, nama-enzyme e-lipase ngezindlela ezihlukile.
Inhloso yokusetshenziswa kwalezi zidakamizwa ukuthuthukisa ukugaya kanye ne-carbohydrate metabolism, ngenxa yokuthi kungenzeka ukuthi kulawulwe kangcono amazinga eglucose, ukunciphisa ingozi yezinkinga, ukuqiniswa kwe-glycogemoglobin futhi kuthuthukiswe inhlala-kahle yomguli.
Elinye lamalungiselelo asetshenziswa kakhulu we-enzyme yiCreon, okuthi, ngaphezu kwenhloso yayo eyinhloko, futhi isize ukudambisa ubuhlungu be-pancreatic.
Ubuhlungu be-pancreatic kungaholela ku-satophobia (ukwesaba ukudla), okunomthelela kuphela ekwakhekeni kwe-hypoglycemia. Ukunciphisa izinhlungu, kunconywa ukusebenzisa ama-analgesics angama-non-narcotic.
Ukuhlinzwa
Sikhuluma nge-autotransplantation yama-islets amaLangerhans kusuka kumnikeli kuya esigulini esigula isifo sikashukela. Ngemuva kokufakelwa, amaseli we-endocrine izicubu aqala ukukhiqiza i-insulin, elawula i-glycemia ngenkuthalo.
Ngemuva kokuhlinzwa okunjalo, i-pancreatic resection noma i-pancreatomy ingenziwa.
Umjovo we-insulin
Uma kunesidingo, nikeza ukungeniswa kwezidakamizwa eziqukethe i-insulin, umthamo wazo kuncike kuzinga le-glucose esegazini, ukudla okudliwayo ekudleni, umsebenzi womzimba wesiguli.
