Ukuvimbela ukumelwa yi-stroke kanye ne-myocardial infaration akuyona umsebenzi olula, odinga ukukhethwa komuthi ofanele. I-Acekardol yisidakamizwa esenziwe eRussia esenzelwe ukunciphisa igazi futhi sinciphise ubungozi bezimo eziyingozi.
INN
Acetylsalicylic acid.
I-ATX
Ikhodi kusigaba samakhemikhali se-anatomical kanye ne-Therapeutic groupation yi-B01AC06.
I-Acekardol yisidakamizwa esenziwe eRussia esenzelwe ukunciphisa igazi futhi sinciphise ubungozi bezimo eziyingozi.
Khipha amafomu nokwakheka
Umuthi wethulwa ngefomu lethebhulethi. Umuthi uqukethe ama-50 mg noma ama-100 mg wezithako ezisebenzayo, ezisetshenziswa ngo-salicylic ester we-acetic acid, i.e. acetylsalicylic acid.
Izithako ezilandelayo zenani elisizayo:
- uwoyela we-castor;
- i-lactose monohydrate;
- I-MCC;
- isitashi;
- i-cellacephate;
- i-talc;
- i-magnesium stearate;
- titanium dioxide;
- i-povidone.
Amathebhulethi ayahlanganiswa, ancibilika kahle emathunjini.
Umuthi wethulwa ngefomu lethebhulethi.
Isenzo se-Pharmacological
Ithuluzi libhekisa kwezidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala ezinomphumela we-antiplatelet. Njengomphumela wethonya lezinto ezisebenzayo, ukukhiqizwa kwe-cycloo oxygenase kwenzeka, okuholela ekuncipheni kobukhulu benqubo yokuhlanganisa iplatelet.
Lapho usebenzisa umuthi ngamanani amakhulu, kuvela umphumela we-antipyretic ne-analgesic.
I-Pharmacokinetics
Ukuhlanganiswa kwamaprotheni egazi kufinyelela ku-66-98%. Le nto isatshalaliswa ngokushesha emzimbeni.
Ukufakwa kwesidakamizwa kwenziwa ngezitho zomgudu wesisu. Ngesikhathi sokufakwa, i-metabolism engaphelele iyenzeka, okuphumela ekwakhekeni kwe-salicylic acid.
Iqoqo eliphakeme lezinto lifinyelelwa ngemuva kwemizuzu eyi-10-20.
Kusho ukuthini i-acecardol?
Izinkomba zokusetshenziswa kwomuthi yilezi:
- ukwephulwa okwesikhashana kokuhlinzekelwa kwegazi ebuchosheni - kusetshenziswa umuthi ukuvikela ukunqotshwa isifo se-ischemic;
- isiguli sinezici ezisongela kusengaphambili: umfutho wegazi ophansi, ukuguga, i-cholesterol ephezulu kanye nokuthuthukiswa kwesifo sikashukela;
- isikhathi ngemuva kokuhlinzwa;
- i-vein thrombosis ejulile;
- isidingo sokwelashwa kwe-angina engazinzile;
- ukuvimbela ukuphazamiseka kokujikeleza okungaholela ekushayweni noma ekushayweni yinhliziyo;
- ukuvimbela i-pulmonary thromboembolism.
Contraindication
Ungasebenzisi umuthi ukwelapha iziguli ezinama-pathologies alandelayo:
- izinkinga zenhliziyo;
- izifo zemvelo yokuwohloka futhi yokulimala kwe-duodenum, isisu nezinye izitho zomgudu wesisu;
- izifo zesibindi;
- i-hemorrhagic diathesis;
- ukuhlaselwa kwe-asthma ye-bronchial evela ekusetshenzisweni kwama-salicylates.
Kunemikhawulo yokuphuza umuthi uma une:
- i-polyposis yakhala;
- i-rhinoconjunctivitis yesikhathi sonyaka;
- ukusabela komzimba okuqubuke phakathi kokusetshenziswa kwezidakamizwa;
- ukukhuphuka kokuhlushwa emzimbeni we-uric acid.
Ungayithatha kanjani?
Umuthi uthathwa isikhathi esingu-1 ngosuku. Ithebhulethi ithathwa ngaphambi kokudla futhi igezwe ngamanzi. Umthamo kuncike enhlosweni yokunquma umuthi:
- ukuvimbela isifo sohlangothi, i-angina pectoris, ukuphazamiseka kwezijikelezo zobuchopho, ukushaya kwenhliziyo - 100-300 mg;
- Izinsolo zokuhlaselwa yisifo senhliziyo esibuhlungu - ama-100 mg nsuku zonke noma ama-300 mg njalo ngosuku.
Ukusetshenziswa kwe-Acecardol, ukubonisana nodokotela kuyimpoqo. Uchwepheshe kuphela ongakhetha umthamo ofanele futhi anikeze inkambo eyanele yokwelashwa. Ukuzelapha ngokwakho kwenqatshelwe.
Kungenzeka yini ukuthi uphuze umuthi onesifo sikashukela?
Isifo sikashukela i-mellitus sikhulisa ubungozi bokuthola izifo ezibonakala ngezinkinga zokujikeleza kwegazi. Ngemuva kokubonisana nochwepheshe, ungasebenzisa umuthi, ngoba kuyadingeka ukuqeda ukwephulwa okunjalo.
Ukusetshenziswa kwe-Acecardol, ukubonisana nodokotela kuyimpoqo.
Imiphumela emibi
Amapheshana wesisu
Nemiphumela emibi yomuthi, kuvela izibonakaliso:
- ukulimala kwe-mucosa emathunjini yizilonda;
- ukwephulwa kwesibindi;
- ukopha esiswini namathumbu;
- Ubuhlungu esiswini;
- ukuhlanza
- ukushaya kwenhliziyo.
Izitho zeHematopoietic
Ukwehlulwa kohlelo lwe-hematopoietic kuholela ekubonisweni okufanayo:
- ukopha okuthe xaxa;
- i-anemia.
Isistimu yezinzwa ephakathi
Uma imiphumela emibi ithinte isistimu yezinzwa ephakathi, isiguli sinezimpawu:
- ukuthikamezwa kwezindlebe;
- ikhanda
- tinnitus;
- isiyezi.
Kusuka ohlelweni lokuphefumula
Imiphumela emibi ingathinta uhlelo lokuphefumula, okuholela ku-spasm ye-bronchi encane nephakathi.
Uma uthathwe ngokungafanele, umuthi ungadala ikhanda kanye ne-tinnitus.
Allergies
Ukusabela komzimba ngenkathi uthatha i-Acecardol kuholela ekubonakalisweni:
- i-angioedema;
- i-cardiorespiratory stress syndrome - isimo esihambisana nokuncipha kwamanani weoksijini kanye nokuqongelela kwezinto zamaselula emaphashini;
- ukulunywa
- imishayo;
- ukudumba kwe-mucosa yamakhala;
- ukwethuka isimo.
Ukusabela komzimba nomuthi kungavezwa ngokuvuvukala kwe mucosa yamakhala.
Imiyalo ekhethekile
Naka imiyalo elandelayo:
- inani elikhulu le-ascorbic acid lingadala ukopha emgodini wokugaya ukudla;
- imithamo emincane ye-ASA ingaholela ku-gout ezigulini ezinamaphutha okuvela kulokhu;
- umphumela wemithi ungahlala kuze kufike isonto eli-1, ngakho-ke udinga ukushiya umuthi isikhathi eside ngaphambi kokuhlinzwa, ngaphandle kwalokho kungenzeka ukuphuma kwegazi kungenzeka.
umphumela wemithi ungahlala kuze kufike isonto elingu-1, ngakho-ke udinga ukushiya umuthi isikhathi eside ngaphambi kokuhlinzwa.
Ukuhambisana notshwala
Ukuphathwa ngokubambisana kotshwala ne-Acecardol kungalimaza isiguli.
Umthelela ekhonweni lokulawula izindlela
Ukunakekelwa kufanele kuthathwe ngezimoto nemishini eyinkimbinkimbi edinga ukwandiswa kwezikhathi zokunakwa. Ngesikhathi sokuthatha umuthi, kunconywa ukuthi uyeke ukushayela.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kuma-trimesters we-1 kanye ne-3 wokuzala ingane, umuthi unomphumela omubi kumama naku-fetus. Okwamanje, umuthi wokukhulelwa awunqatshelwe.
Kwezinye izinkathi, ukunikezwa kwesidakamizwa kwenzeka phambi kobufakazi obalulekile. Ngaphezu kwalokho, udinga ukuhlola izinga lezinzuzo ze-Acecardol kanye nobungozi obungathinta ukukhula kwesibeletho.
Ama-Metabolites angena ebisini, ngakho-ke akunconywa ukusebenzisa umkhiqizo ngesikhathi sokuncelisa ibele. Uma isidingo sokuthatha i-Acecardol siphezulu, khona-ke ingane idinga ukudluliselwa ekunikezelweni kokufakelwa.
Ukuphathwa kwe-Acecardol ezinganeni
Umuthi awubekelwe ukwelashwa kweziguli ezineminyaka engaphansi kweminyaka engu-18.
Sebenzisa ebudaleni
Ukwemukelwa kwezimali ekugugeni kufanele kwenziwe ngaphansi kokuqondisa kukachwepheshe.
Ukweqisa
Ukusetshenziswa kwe-Acecardol ngamanani aphakeme kunalawo anqunywe ngudokotela kuholela ekutholakaleni kwalezi zibonakaliso:
- i-alkalosis yokuphefumula ehambisana nokwanda kwenani lama-alkaline complements emzimbeni;
- ukuphefumula ngokushesha;
- ukudideka kokwazi;
- ikhanda;
- ukukhuphuka kokujuluka;
- tinnitus;
- ukuhlanza
- Isiyezi
- hyperventilation
Ezimweni ezinzima, isimo sesiguli sibonisa izimpawu ezilandelayo:
- ukucindezelwa kwenhliziyo;
- qeda;
- ukuvuvukala kwamaphaphu;
- izinga lokushisa lomzimba eliphakeme;
- ukwehluleka kwezinso;
- coma;
- iminyakazo
- isithulu.
Uma kuvela izimpawu ze-overdose, ukuya esibhedlela kufanele kube ngokushesha.
Ezimweni ezimbi kakhulu ze-overdose, kungavela isimo sokuqina.
Ukuxhumana nezinye izidakamizwa
Ama-ejenti alandelayo athinta umuthi:
- I-Glucocorticosteroids. Kukhona buthaka izakhiwo zokuphulukisa zama-salicylates kanye nokuqothula okwandayo.
- Ama-antiplatelet agents, izidakamizwa ze-thrombolytic kanye nama-anticoagulants. Ingozi yokopha iyakhuphuka.
Ukusetshenziswa kwe-Acecardol kubangela ukuqina kwesenzo semithi elandelayo:
- izidakamizwa ze-diuretic;
- i-angiotensin eguqula ama-enzyme (ACE) inhibitors;
- ama-oricosuric agents.
I-acetylsalicylic acid iholela ekwandeni komphumela wezokwelapha wale mithi elandelayo:
- I-Digoxin;
- I-Methotrexate;
- I-Valproic acid;
- okuvela kwe-sulfonylurea ne-insulin.
Ama-Analog
Kusho okunomphumela ofanayo kufaka phakathi:
- U-Aspirin Cardio - umuthi one-ASA. Inempahla ye-antiplatelet.
- I-Cardiomagnyl - amaphilisi okuvimbela ukubanga kwegazi.
- I-Aspen isidakamizwa esilwa nokuvuvukala sohlobo lwe-non-steroidal equkethe i-acetylsalicylic acid ekwakhiweni kwayo.
- I-Aspicore umuthi onomphumela we-analgesic ne-antipyretic. Ithinta kahle imithambo yegazi nemithambo ngenxa yempahla yayo ye-antiplatelet.
- I-Persantine iyisidakamizwa ngendlela yesisombululo semijovo. Umuthi kuhloswe ngawo ukulungisa i-microcirculation kanye ne-platelet discgregation.
- I-ThromboASS yisidakamizwa esisetshenziselwa ukuvikela izifo zenhliziyo ezi-coronary, ukushaya kwenhliziyo, imithambo ye-varicose nezinye izifo.
Imibandela yekhefu lekhemisi
Ngaphandle kwencwadi kadokotela.
Intengo ye-Acecardol
Izindleko - kusuka kuma-ruble ayi-17 kuye kwangama-34.
Izimo zokugcina izidakamizwa i-Acekardol
Umuthi kufanele ube sendaweni emnyama neyomile.
Impilo yeshelf umuthi
Isikhathi sokugcina umuthi asidluli iminyaka emi-3.
Umuthi uyatholakala ngaphandle kadokotela.
Ukubuyekezwa ku-Acecardol
UVadim, oneminyaka engama-45, uBirobidzhan
Phakathi kwezidakamizwa engangizisebenzisa ukwenza ngcono ukujikeleza kwe-cerebral, lesi sidakamizwa sihamba phambili. Ngosizo lwe-Acecardol wakwazi ukwelulama ekuhlaselweni yisifo sohlangothi. Umkhiqizo uvimba kahle igazi futhi akubangeli ukusabela okuvela ngaphandle. Ngaphezu kwalokho, umuthi usezingeni lentengo ephansi, ngakho-ke umuthi utholakala kuwo wonke umuntu.
U-Elena, oneminyaka engama-56, u-Irkutsk
I-Acekardol ilondolozwe isikhathi esingaphezu kweminyaka emi-5. Umuthi uthatha indawo yezidakamizwa ezibizayo okungewona wonke umuntu onenkinga yenhliziyo angakwazi ukuzikhokhela. Ithuluzi lalinqunywe ngudokotela wenhliziyo. Ngiphuza amaphilisi ngemuva kokudla. Ngemuva kokuphothula izifundo, thatha ikhefu bese uphinda ukwelashwa.
U-Olga, oneminyaka engama-49, uChelyabinsk
Ukusebenziseka kalula, ukungabikho kwemiphumela emibi nezindleko eziphansi kuyizinto eziphambili ze-Acecardol. Ngemuva kokuqunjelwa yi-myocardial, ngisebenzisa lesi sidakamizwa njalo. Ngesikhathi sokusebenzisa umuthi awutholanga maphutha.
