Izibhebhe ze-Berlition 600: imiyalo esetshenzisiwe

Amathebhulethi we-Berlition 600 mg asondele kumavithamini e-B ekubhekeni kwawo kokuphilayo. Umuthi usiza ukuvumelanisa izinqubo ze-metabolic futhi uthuthukise izicubu ze-trophic nerve. Kuyasebenza futhi njenge-hepatoprotector nasekwelapheni okuyinkimbinkimbi kwama-neuropathies emvelaphi ehlukahlukene.

Igama Lezwe elingafanele

I-INN yesidakamizwa - i-Thioctic acid (Thioctic acid).

I-ATX

Umuthi ungowamaqembu wemithi wama-metabolic nama-hepatoprotective agents ane-ATX code A16AX01.

I-Berlition 600 mg ekukhiqizweni kwabo okusondelene namavithamini e-B.

Ukwakheka

Ingxenye esebenzayo yeBerlition yi-α-lipoic (thioctic) acid, ebizwa nangokuthi yi-thioctacid. Indlela yomlomo yesidakamizwa imelelwa ngamaphilisi angama-300 nama-600 mg kanye namaphilisi ahlanganisiwe anokuqukethwe okusebenzayo kwe-300 mg. Ukwakheka okwengeziwe komkhiqizo obhebhekiwe kumelelwa yi-lactose monohydrate, i-colloidal silicon dioxide, i-microcellulose, i-povidone, i-croscarmellose sodium, i-magnesium stearate. Ukuhlanganiswa kwefilimu kwakhiwa nge-hypromellose, titanium dioxide, uwoyela wamaminerali, i-sodium lauryl sulfate nodayi u-E110 no-E171.

Bheka futhi: Burliton 300

Izibhebhe zeBerliton - imithamo, izinkambiso, ngaphezulu kule ndatshana

Izibhebhephuzi eziphuzi ziyindingilizi kanti ngakolunye uhlangothi zisengozini ngakolunye uhlangothi. Zigcwele izingcezu eziyi-10. emabhulashini, abekwe izingcezu ezi-3. emabhokisini amakhadibhodi. Igobolondo elithambile lamaphakethi lipinki ngombala. Igcwele umuthi ophuzi we-pasty. Amaphilisi angama-15 isatshalaliswa emaphaketheni weseli. Emaphepheni amakhadibhodi, kubekwa amaqabunga ama-1 noma ama-2 blister kanye nepheshana lemiyalo.

Futhi, umuthi uyatholakala ngesimo se-concentrate. Isixazululo esiyinyumba sokungenelela silungiselelwe kusuka kuso. Umuthi osebenzayo umelwe usawoti we-ethylene diamine ngenani elilingana no-600 mg we-lipoic acid. Njenge-solvent, kusetshenziswa amanzi okujova. Uketshezi uhanjiswa emafulethini ayi-12 noma ama-24 ml. Ephaketheni angaba ama-10, 20 noma ama-30 ama-PC.

Izibhebhe ze-Berlition ziyindilinga futhi ziphuzi ngombala.

Ukulungiswa kwe-capsule kupinki ngombala.

Umuthi uyatholakala ngesimo sokugxilisisa.

Isenzo se-Pharmacological

I-A-lipoic acid yisakhi esinjengevithamini esifana namavithamini e-B. Inomphumela oqondile nengaqondile kuma-radicals wamahhala, ibonisa izakhiwo ze-antioxidant, futhi futhi isebenze umsebenzi wamanye ama-antioxidants. Lokhu kukuvumela ukuthi uvikele iziphetho ze-nerve kusuka emonakalweni, uvimbele inqubo ye-glycosylation yezakhi zamaprotheni kwizifo sikashukela, kusebenze i-microcirculation kanye nokujikeleza kwe-endoneural.

I-Thioctacid iyi-coenzyme ye-multimolecular mitochondrial enzyme complexes futhi ibamba iqhaza ku-decarboxylation ye-alpha-keto acid. Iphinde yehlise inani le-glucose egazini le-plasma, ikhuphula ukugcwala kwe-glycogen ezinhlakeni zesibindi, ikhuphule umuzwa womzimba we-insulin, ibandakanyeka kumandla we-lipid-carbohydrate metabolism, futhi isize ukuguquguqula amazinga e-cholesterol.

Ngaphansi kwethonya lazo, ulwelwesi lwamaseli luyavuselelwa, ukuqina kweseli kuyanda, ukusebenza kohlelo lwezinzwa oluphelele kuyathuthukiswa, i-metabolism ye-glucose ehlukile iyathuthukiswa, okubaluleke kakhulu kwiziguli ezinesifo sikashukela i-mellitus. I-Thioctic acid inomphumela onenzuzo kuma-hepatocytes, ebavikela emiphumeleni elimazayo yama-radicals wamahhala nezinto ezinobuthi, kufaka phakathi imikhiqizo ye-metabolism ye-ethanol.

Umuthi ubuyisela ulwelwesi lweseli.

Umuthi uthuthukisa enye i-glucose metabolism.

I-Berlition ithuthukisa ukusebenza kohlelo lwezinzwa.

Ngenxa yezimpawu zayo ze-pharmacological, i-thioctacid inemiphumela elandelayo emzimbeni:

• ukwehliswa kwe-lipid;
• i-hypoglycemic;
• i-hepatoprotective;
• i-neurotrophic;
• ukukhipha izidumbu;
• antioxidant.

I-Pharmacokinetics

Umuthi ngemuva kokuphathwa ngomlomo amahora angama-0.5-1 ungeniswa egazini cishe ngokuphelele. Ukugcwala kwesisu kuvimbela ukumunwa kwawo. Sisakazekela ngokushesha kwezicubu. I-bioavailability ye-lipoic acid isuka kuma-30-60% ngenxa yomkhuba we- "pass yokuqala". I-metabolization yayo yenziwa ikakhulukazi nge-conjugation ne-oxidation. Kufika ku-90% wesidakamizwa, ikakhulukazi esimweni sama-metabolites, sikhishwa emchameni imizuzu engu-40-100 ngemuva kokuphathwa.

Umuthi ngemuva kokulawulwa amahora angama-0.5-1 ungeniswa egazini cishe ngokuphelele.

Izinkomba zokusetshenziswa kwamatafula i-Berlition 600

Umuthi uvame ukubekelwa i-polyneuropathy, ubonakaliswa ngendlela yobuhlungu, ukushiswa, ukulahleka kwesikhashana kwemizwa yezitho. Lokhu kudalwa kwengqondo kungadalwa yisifo sikashukela, ukusebenzisa kabi utshwala, ukutheleleka ngegciwane noma ngegciwane (njengezinkinga, kubandakanya ngemuva komkhuhlane). Umuthi futhi usetshenziswa ekwelapheni okuyinkimbinkimbi lapho ukhona:

• hyperlipidemia;
• ukonakala kwamafutha kwesibindi;
• i-fibrosis noma i-cirrhosis;
• i-hepatitis A noma ifomu lesifo esingalapheki (uma kungekho i-jaundice enkulu);
• ubuthi obangelwa amakhowe anobuthi noma izinsimbi ezisindayo;
• i-coronary atherosclerosis.

I-Berlition isetshenziselwa i-hyperlipidemia.

Umuthi ubekelwe ukuwohloka kwamafutha kwesibindi.

Umuthi lo usetshenziswa lapho kukhona ubuthi obudalwa amakhowe anobuthi.

Umuthi wokwelashwa kwe-coronary atherosulinosis.

Kwezinye izimo, kungenzeka ukusebenzisa i-Berlition njenge-prophylactic.

Contraindication

Umuthi awunqunyelwe ngokunyuka kokuxakaniseka kwesenzo se-thioctic acid kanye nokungabekezelelani kwezingxenye ezisizayo. Okunye ukwephulwa:

• ukukhulelwa
• i-lactation ngaphandle kokuphazamiseka kokuncelisa ibele;
• iminyaka engu-18.

Ezigulini ezinesifo sikashukela i-mellitus, umuthi kufanele usetshenziswe ngokucophelela ngenxa yengozi ye-hypoglycemia.

Ungawaphuza kanjani ama-Berlition amaphilisi angama-600

Ukuphathwa ngomlomo kwesidakamizwa kwenziwa esiswini esingenalutho. Izibhebhe kufanele zigwinywe ngaphandle kokuhlafuna futhi ziphuze ngenani elidingekayo lamanzi. Yidla ngokushesha ngemuva kwalokhu akufanele kube khona, linda okungenani imizuzu engama-30. Umthamo ofanele ubekwa udokotela oholayo.

Umuthi awuchaziwe ngesikhathi sokukhulelwa.

Kwabadala

Umthamo wansuku zonke wezidakamizwa ungahlukahluka ngokuya ngobunzima balesi sifo. Uthathwe ngokugcwele ngomlomo ngesikhathi, mhlawumbe ngaphambi kokudla kwasekuseni, kwesinye isikhathi ukuvunyelwa kwesikhathi 2 kuvunyelwe. Ngokuvamile, inkambo ende yokwelashwa iyadingeka.

Ezilondeni ezinzima, kunconywa ukuqala ukwelashwa ngokuphathwa kwabazali be-Berlition ngendlela ye-infusions.

Isixazululo kufanele siphathwe ngokudonsa. Ngemuva kwamasonto angama-2-4, ukwelashwa kuyaqhubeka ngamathebulethi noma ngamaphilisi.

Okwezingane

Izinhlobo zomlomo zesidakamizwa azinqunyelwe izingane kanye nentsha. Yize kunamacala angawodwa kokusetshenziswa kwawo ngempumelelo ekwelapheni i-thyroid pathologies ngemuva kokwehluka ngama-rickets, i-Down syndrome kanye nokunye ukungahambi kahle.

Izinhlobo zomlomo zesidakamizwa azinqunyelwe izingane kanye nentsha.

Ngoshukela

Ekwelashweni kwe-polyneuropathy yesifo sikashukela, kubalulekile ukulondolozela ukuqina koshukela egazini ezingeni elifanele. Kungadingeka ukuthi kulungiswe imithamo yama-hypoglycemic agents athathwe yisiguli.

Imiphumela emibi ye-Berlition amaphilisi angama-600

Ngokuphathwa komlomo umuthi, kungavela ukusabela okuhlukahlukene okungathandeki:

1. Isicanucanu, ukuhlanza.
2. Nambitha ukungalingani.
3. Ukuphakama kokudla.
4. Ubuhlungu esiswini.
5. I-Hyperhidrosis.
6. Okuhlosiwe.
7. I-Hypoglycemia

Umuthi ungabonakala njengempendulo, njengokucanuzelelwa kwenhliziyo, ukuhlanza.

Ukusabela kokuthatha umuthi kubuhlungu esiswini.

Lapho uthatha i-Berlition, i-hyperhidrosis ingavela.

Lapho uthatha umuthi, i-purpura ingavela.

Izitho zeHematopoietic

I-Thrombocytopenia kungenzeka, yize lokhu kuyinto ebonakala kakhulu lapho umuthi uphathwa ngaphakathi.

Isistimu yezinzwa ephakathi

Ubuhlungu bekhanda, umuzwa wobunzima endaweni yekhanda, ama-cramps, isiyezi, ukhubazeka okubukwayo (umbono ophindwe kabili) kungavela.

Allergies

Izimpawu ze-allergic ziboniswa ngesimo sokuqubuka komzimba, ukulunywa, i-erythema. Amacala e-anaphylaxis ayaqoshwa.

Umthelela ekhonweni lokulawula izindlela

Ayikho imininingwane ethile. Njengoba kunikezwe ithuba lokuba nesiyezi, i-syndrome ethokomayo kanye nezimpawu ze-hypoglycemia, kufanele kuqashelwe lapho ushayela noma usebenza ngamasu angaba yingozi.

Izimpawu ze-allergic ziboniswa ngesimo sokugoqeka komzimba, ukulunywa.

Imiyalo ekhethekile

Ukuqapha njalo kwenkomba ye-glycemic ku-diabetesics kuyadingeka. Ngesikhathi sokulashwa naphakathi kwezifundo zokwelapha, kufanele ubushiye ngokuphelele utshwala futhi ungasebenzisi izingoma eziqukethe utshwala ngaphakathi.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Thatha umuthi osesiteji sokuzala ingane awunconywa. Ngesikhathi sokwelashwa, omama kufanele bayeke ukondla ngokwemvelo, ngoba abukho ubufakazi bokuthi i-thioctacid idlulela obisini lwebele nokuthi ithinta ini emzimbeni wezingane.

Ukweqisa

Uma imithamo evumayo idluliwe, ikhanda, isicanucanu, nokuhlanza kukhula. Ukubonakaliswa okuvusa inkanuko, i-lactic acidosis, ukuphazamiseka kwemvelo kungenzeka.

Iziguli ezinesifo sikashukela zingawela enkingeni ye-hypoglycemic.

Uma kutholakala izimpawu ezethusayo, ukuhlaselwa kokuhlanza kufanele kuvuswe, thatha i-sorbent bese ufuna usizo lodokotela. Ukwelashwa kugxilwe ngokubonakalayo.

Uma kwenzeka wenza ngokweqile, thola usizo lwezokwelashwa.

Ukuxhumana nezinye izidakamizwa

Isenzo se-Berlition senziwa buthaka phambi kwe-ethanol nemikhiqizo yayo yokubola.

Ngenxa yekhono le -icicic acid yokwakha izinhlanganisela eziyinkimbinkimbi, lo muthi awuthathwa kanye nezinto ezifana:

• amalungiselelo e-magnesium noma e-iron;
• Isixazululo se-ringer;
• izixazululo ze-fructose, ushukela, i-dextrose;
• imikhiqizo yobisi.

Isikhathi sokuphuza kwabo kufanele okungenani sibe ngamahora ambalwa.

I-Berlition ithuthukisa imiphumela ye-insulin, izidakamizwa ze-hypoglycemic ezithathwe ngomlomo, kanye ne-carnitine. Ukuphathwa okuhlanganisiwe kwalesi sidakamizwa okukhulunywa ngaso neCisplatin kwenza buthaka ukusebenza kwalesi sikhathi.

Isikhathi sokuphuza kwabo kufanele okungenani sibe ngamahora ambalwa.

Ama-Analog

Njengokuthi uthathe isikhundla somuthi okukhulunywa ngawo, ungasebenzisa izidakamizwa ezilandelayo:

• Neuroleipone;
• I-Thioctacid;
• I-Oktolipen;
• I-Thiogma;
• U-Espa Lipon;
• Tiolepta;
• Lipamide;
• I-Thiolipone;
• i-lipoic acid, njll.

Imibandela yekhefu lekhemisi

Umuthi awutholakali esizindeni somphakathi.

Ngingakwazi ukuthenga ngaphandle kadokotela

Amaphilisi atholakala ngomuthi kuphela.

Intengo

Umuthi osefomini yethebhulethi uthengiswa eRussia ngentengo yama-ruble angama-729. Intengo yakhona emakhemisi e-Ukraine ifinyelela kuma-399 UAH ngama-30 ama-pcs.

Izimo zokugcina zomuthi

Gcina umuthi kude nezingane. Ukushisa kwesitoreji akufanele kudlule + 25 ° C.

Isikhathi sokuphelelwa yisikhathi

Amathebhulethi angagcinwa iminyaka engu-2 kusukela ngosuku lokukhishwa.

Ngemuva kosuku lokuphelelwa yisikhathi, ukuthatha umuthi akuvunyelwe.

Umkhiqizi

Amacwecwe ama-Berlition akhiqizwa yinkampani yezokwelapha yaseJalimane iBerlin-Chemie AG Menarini Group.

Ukubuyekezwa

Umuthi uthola izibuyekezo eziningi ezinhle ezivela kodokotela nasezigulini.

Odokotela

UMikoyan R.G., oneminyaka engama-39, uTver

Abalingani bami abaningi bayangabaza iBerlition. Kepha kusebenza kahle bobabili ekuvinjelweni kwezilonda zohlelo lwezinzwa oluyingozi, nasekwelapheni ama-neuropathies ezigulini ezinesifo sikashukela.

Lo muthi awuthathwa nge-t Glucose.

Iziguli

UNikolay, oneminyaka engama-46, uRostov

Ngenxa yezinkinga notshwala, impilo yaqala ukuba limp. Kwafika eqophelweni lokuthi ngake ngakwazi ukuphuma embhedeni ekuseni - imilenze yami ngezansi ibonakala sengathi ikhubazekile. Kwavela ukuthi le yi-polyneuropathy, eyavela ngenxa yotshwala. I-Berlition yaqale yadonswa emthanjeni, ngabe ngiyiphuza ngamaphilisi. Ngenxa yezidakamizwa kanye ne-physiotherapy, ukuhamba kwemilenze kubuyiselwe ngokuphelele. Ngingene otshwaleni ngiphuza amaphilisi okuvimbela kanye ngonyaka.