Ungayisebenzisa kanjani isidakamizwa i-Lozap Plus?

I-Lozap Plus - isidakamizwa sokunciphisa ingcindezi ibe sezingeni elijwayelekile. Ngenxa yomuthi, umthwalo osenhliziyweni uyancishiswa, ngakho-ke, ingozi yokuthola ukuphazamiseka ku-myocardium inciphile.

I-ATX

Ikhodi ye-ATX yi-C09DA01.

I-Lozap Plus - isidakamizwa sokunciphisa ingcindezi ibe sezingeni elijwayelekile.

Khipha amafomu nokwakheka

Into esebenzayo yi-12.5 mg ye-hydrochlorothiazide ne-50 mg ye-losartan potassium. Izici zesimo esisizayo yilezi:

• i-simethicone emulsion;
• i-croscarmellose sodium;
• Udayi obomvu
• I-MCC;
• udayi ophuzi we-quiniline;
• i-hypromellose;
• i-mannitol;
• titanium dioxide;
• i-macrogol;
• i-magnesium stearate.

Khipha umuthi ngendlela yamathebulethi ngokuhlanganiswa kwefilimu.

Khipha umuthi ngendlela yamathebulethi ngokuhlanganiswa kwefilimu.

Isenzo se-Pharmacological

IHydrochlorothiazide iyi-diuretic, ne-potassium losartan yi-angiotensin II receptor blocker. Ngenxa yokuba khona kwalezi zinto, umuthi unemiphumela elandelayo:

• kwehlisa umfutho wegazi;
• kunciphisa ukuhlanganiswa kwe-potassium ku-plasma yegazi;
• inomphumela we-uricosuric.

I-Pharmacokinetics

IHydrochlorothiazide ayikhishwa obisini futhi ayiweli emvinjelweni wegazi-ubuchopho. Kodwa-ke, into iyakwazi ukungena egazini le-fetoplacental. Into isuswe yizinso. Ayikhiqizwanga.

Umuthi unciphisa ukugcotshwa kwe-potassium eseplasma yegazi.

Ehlelweni lwe-metabolism, i-losartan iba yi-metabolite, eboshelwe kumaprotheni egazi angama-99%. Ukuhlushwa okuphezulu kwenzeka ngemuva kwamahora ama-3. Umuthi udonswa ngokushesha.

Izinkomba zokusebenzisa i-Lozap plus

Umuthi wenzelwe ukusetshenziswa kulezi zimo ezilandelayo:

• ukunciphisa ingozi yezifo zohlelo lwezinhliziyo ngokumelene nesizinda sehypertular hypertrophy;
• nge-hypertension ye-arterial;
• ukunciphisa amathuba okuba nesifo senhliziyo noma unhlangothi.

Contraindication

Contraindication wethulwa yile mibandela elandelayo:

• ukonakala okukhulu kokusebenza kwezinso;
• gout
• uhlobo lokuphikisa lwe-hyperkalemia;
• ukwehla kokugeleza kwe-bile ku-duodenum;
• izilonda ezithintekayo ezithinta ipheshana le-biliary;
• ukuzwela okuphezulu kwezinto ezisetshenziselwa ukwelashwa;
• Anuria
• ukungasebenzi kahle kwesibindi;
• ukuncishiswa okuphikisayo kwenani le-sodium ne-potassium.

I-Lozap Plus icutshaniswe nokulimazeka okukhulu kwezinso.

I-Lozap Plus i-contraindication uma kungenzeka uzwele okuphezulu ezintweni ezikhona ekwelashweni.

I-Lozap Plus ivunyelwe ku-gout.

Ngaphezu kwalokho, akunconywa ukusebenzisa umkhiqizo wabesifazane abalungiselela ukukhulelwa ingane.

Ngokunakekela

Izifo ezilandelayo kanye nokuphazamiseka kudinga ukuqashelwa:

• i-hyponatremia;
• ukwehluleka kwenhliziyo;
• i-renal artery stenosis;
• i-magnesium ephansi yegazi;
• i-cardiomyopathy evimbayo;
• i-pathology yezicubu ezithintekayo;
• hyperkalemia
• isifuba somoya, kufaka phakathi ama-anamnesis;
• uhlobo lokuqala lokukhiqizwa kwamanani akhuphukile we-aldosterone;
• i-mitral noma i-aortic stenosis;
• i-cerebrovascular pathology.

Umuthi uthathwa ngokuqapha ekwehlulekeni kwenhliziyo.

Umuthi uthathwa ngokuqapha ku-asthma.

Umuthi uthathwa ngokuqapha ku-cardiomyopathy ethambisayo.

Ungayithatha kanjani

Izici zokusetshenziswa kwomuthi zincike ezinhlosweni nakulesi sifo:

1. Ukunciphisa ubungozi bokukhula kwe-pathologies yesifo senhliziyo, qala ngethebhulethi elilodwa ngosuku, uma kunesidingo, ulethe umthamo kumathebulethi ama-2.
2. Ngomfutho wegazi ophakeme - isikhathi esingu-1 ngosuku. Uma kungekho mphumela ofunekayo, khona-ke umthamo ungandiswa.

Umthamo ngqo ukhethwa udokotela, ngakho-ke qiniseka ukubonisana nochwepheshe ngaphambi kokuqala ukwelashwa.

Ukusetshenziswa komkhiqizo kuzimele kokudla.

I-Lozap plus ithatha yiphi ingcindezi

Umuthi unikezwa kuphela ngomfutho wegazi ophakeme.

Umuthi unikezwa kuphela ngomfutho wegazi ophakeme.

Ekuseni noma kusihlwa

Kunconywa ukuthatha umuthi ekuseni. Uma kunesidingo, umuthi usetshenziswa izikhathi ezi-2 ngosuku - ngemuva kokuvuka nakusihlwa.

Kungenzeka yini ukuthi uphuze umuthi onesifo sikashukela

Umuthi uthathwa kuphela ngemvume kadokotela, ngoba umuthi ubangela ukubekezelelwa kwe-glucose engalungisiwe.

Imiphumela emibi

Lapho unaka amathuba okuphendula okungekuhle.

Amapheshana wesisu

Isimo sibonisa izimpawu:

• ukuhlanza
• umlomo owomile
• isicanucanu
• cramping;
• ukuqunjelwa
• Izimpawu dyspeptic;
• ukuthopha;
• i-pancreatitis
• i-gastritis;
• ukuvuvukala kwezindlala zesisu.

Imiphumela emibi evela emapheshana esiswini: ukukhuphula i-pancreatitis engamahlalakhona.

Imiphumela emibi evela emgodini wokugaya ukudla: ukugabha.

Imiphumela emibi evela emgodini wesisu: isicanucanu.

Izitho zeHematopoietic

Kunezimpawu eziseceleni:

• i-anemia, kufaka phakathi uhlobo lwe-hemolytic ne-aplastic;
• i-leukopenia;
• i-thrombocytopenia;
• i-agranulocytosis.

Isistimu yezinzwa ephakathi

Ngasohlangothini lohlelo lwezinzwa oluphakathi kunezimpawu:

• i-peripheral neuropathy;
• ukudideka kokwazi;
• ukuqwasha
• ukukhuphuka kokukhathazeka;
• inkinga yokulala;
• ukuhlaselwa ukwethuka;
• ukuthuthumela
• amaphupho amabi;
• Ukukhathazeka
• i-migraine
• izimo zokwehluleka.

Kusukela ohlangothini lwesistimu yezinzwa ephakathi kunezimpawu zokuqwasha.

Kusukela ohlangothini lwesistimu yezinzwa ephakathi kunezimpawu ze-migraine.

Ngasohlangothini lohlelo lwezinzwa oluphakathi kunezimpawu zokufiphala.

Kusuka ohlelweni lomchamo

Isiguli sinezimpawu ezilandelayo eziseceleni:

• ukwanda kokuhlangana ebusuku ubusuku besikhathi sasemini;
• ukunxenxa njalo ukukhipha isinye;
• izinso ezingasebenzi kahle;
• inqubo yokuvuvukala ethinta ipheshana lomchamo;
• ukuba khona kwe-glucose kumchamo.

Kusuka ohlelweni lokuphefumula

Ekuphendukeni okubi, ukubonakaliswa kuyimpawu:

• i-pulmonary edema yemvelaphi engeyona ye-cardiogenic;
• ukuhlulwa kwezono zekhala;
• ukukhwehlela
• ukucinana kwamakhala;
• ukungaphatheki kahle umphimbo;
• i-bronchitis;
• ukuvuvukala kwezicubu ze-pharynx nolwelwesi lwama-mucous larynx.

Imiphumela emibi evela ohlelweni lokuphefumula ibonakala ngokukhwehlela.

Kwi-bronchitis engapheli, isidakamizwa sithathwa izinsuku ezingama-5.

Imiphumela emibi evela ohlelweni lokuphefumula ibonakala ngokuxinana kwamakhala.

Kusuka emasosheni omzimba

Isiguli siyavela:

• ukusabela kwe-anaphylactic;
• uhlobo lwe-angioneurotic lwe-edema;
• umkhuhlane we-nettle.

Kusuka enhliziyweni

Ukulimala enhliziyweni ngokusabela okubi kubangela ukwakheka kwezimpawu:

• i-ventricular fibrillation;
• ukukhuphuka kwenhliziyo;
• uhlobo lwe-sinus bradycardia;
• Ubuhlungu ku-sternum;
• imvelo ye-orthostatic ye-arterial hypotension.

Ukulimala enhliziyweni ngokusabela okungekuhle kubangela ukwakheka kwemvamisa yokuqina kwenhliziyo.

Ukulimala enhliziyweni ngokusabela okubi kubangela ukwakheka kobuhlungu ku-sternum.

Ukulimala enhliziyweni ngokusabela okubi kuba imbangela yokwakheka kwe-sinus hlobo bradycardia.

Engxenyeni yesibindi ne-biliary

Izimpawu ezilandelayo zemiphumela emibi zibonisa ipheshana lesibindi kanye nesibindi:

• cholecystitis;
• i-cholestatic jaundice;
• ukungasebenzi kahle kwesibindi.

Kusuka ezicutshini zemisipha

Isiguli sinokuboniswa okulandelayo:

• ukungahambi kahle emisipha nasekuhlanganeni;
• iminyakazo
• i-fibromyalgia;
• ukuvuvukala
• Ubuhlungu emhlane kanye nokuhlangana: i-hip, ihlombe kanye nedolo;
• isifo samathambo.

Kusukela ohlangothini lwezicubu zomzimba kanye nezicubu ezithintekayo, isiguli sihlakulela isifo samathambo.

Ngasohlangothini lwezicubu zomzimba nezesikhumba esikhanyayo, isiguli sihlakulela ubuhlungu emuva.

Ngasohlangothini lwezicubu zomzimba nezesikhumba esikhanyayo, isiguli sihlakulela ukushuba.

Allergies

Izimpawu ezilandelayo zokusabela komzimba zingenzeka:

• umkhuhlane;
• ukuvuvukala
• ukungahambi kahle ngendlela yokushiswa nokulunywa;
• ubomvu besikhumba.

Imiyalo ekhethekile

Umuthi awusetshenziswa ngaphambi kokuhlola ukusebenza kwezindlala ze-parathyroid, ngoba umuthi uyakwazi ukuba nomthelela ongemuhle kumphumela wokuxilongwa.

Ukuqokwa kwe-Lozap Plus yezingane

Umuthi lo uphethwe ngemishanguzo yokwelapha izingane. Imiyalo ikhombisa ukuthi iziguli ezingaphansi kweminyaka engu-18 azinikezwa umuthi obekiwe, ngoba azikho izifundo ezenziwayo zokuthola ukuphepha kanye nokusebenza kahle kwalo muthi.

Umuthi lo uphethwe ngemishanguzo yokwelapha izingane.

Sebenzisa ebudaleni

Ngesikhathi sokwelashwa kweziguli ezingaphezu kweminyaka engama-65 ubudala, asikho isidingo sokulungiswa komthamo.

Ukukhulelwa nokukhulelwa

Ukuthatha umuthi ku-1, 2nd kanye ne-3th trimesters of ukukhulelwa kuholela kumthelela omubi ekuthuthukisweni kwe-fetus, ngakho-ke, umuthi awusetshenziswa ngesikhathi sokukhulelwa.

Ukuze wenze ukwelashwa ngesikhathi sokukhulelwa, kufanele wenqabe ukuncelisa ibele noma ukhethe omunye umuthi.

Ukuhambisana notshwala

Ukusetshenziswa kanyekanye kweLozap Plus nemikhiqizo equkethe utshwala kuholela ezinkingeni. Ukuphuza utshwala ngesikhathi sokwelashwa akuvunyelwe.

Umthelela ekhonweni lokulawula izindlela

Kuyadingeka ukwenqaba ukushayela ngenxa yomphumela wesidakamizwa esilinganisweni sokuphendula kanye nokuhlushwa.

Kuyadingeka ukwenqaba ukushayela ngenxa yomphumela wesidakamizwa esilinganisweni sokuphendula kanye nokuhlushwa.

Ukweqisa

Izimpawu zokweqisa:

• i-bradycardia;
• ukuntuleka kwama-electrolyte;
• i-tachycardia;
• umfutho wegazi ophansi.

Ngezibonakaliso ezinjalo, ngokushesha baya esibhedlela. Isiguli sinqunywe i-gastric lavage kanye nokwelashwa okuhloswe ngaso ukuqeda ukubonakaliswa.

Ukuxhumana nezinye izidakamizwa

Lapho uthatha i-hydrochlorothiazide, kunezici ezilandelayo zokusebenzisana kwayo nemithi:

• ama-laxatives kanye ne-corticosteroids - ingozi eyandayo yokuntuleka kwe-electrolyte;
• ama-ejenti ahlukile ne-iodine - amathuba okuthola ukuhluleka kwe-renal ngesikhathi sokukhuphuka komzimba;
• I-Carbamazepine - inomthelela ekutholakaleni kwe-hyponatremia;
• i-glycosides ye-cardiac - ingozi yama-arrhythmias iyanda;
• I-Methyldopa - i-hemolytic anemia ingavela;
• ama-salicylates - andisa umphumela ongemuhle ohlelweni lwezinzwa oluphakathi lapho usebenzisa i-hydrochlorothiazide ngamanani amakhulu;
• izidakamizwa ze-anticholinergic - i-bioavailability ye-diuretics ehlobene neqembu le-thiazide lenyuka;
• imithi ene-lithium - umphumela onobuthi uyathuthukiswa;
• ama-antihypertensive agents - umphumela wokungezelela kwenzeka.

Ukusebenzisana kweLozap Plus ngama-glycosides enhliziyo kukhulisa ubungozi be-arrhythmias.

Ngokusebenzisana kweLozap Plus neCalcium D3, kuyadingeka ukubheka ukugcwala kwe-calcium emzimbeni wesiguli.

Ukusebenzisana kweLoapap Plus nge-carbamazepine kunomthelela ekutholakaleni kwe-hyponatremia.

Ukuba khona kwe-losartan eLozap Plus kumelelwa yizimpawu ezifanayo zokusebenzisana kwezidakamizwa:

• izidakamizwa ze-antipsychotic kanye ne-tricyclic depressants - amathuba wokuqalwa kwe-arterial hypertension nokwanda;
• I-Aliskiren - icutshaniswe neziguli ezinesifo sikashukela ngokumelene nesizinda sokwehluleka okukhulu kwe-renal noma okulinganiselayo;
• Ama-NSAIDs - umphumela weLozap worsens;
• izidakamizwa ze-diuretic zohlobo lwe-potassium-sparing - amathuba okukhula kwe-potassium ekhuphukeni kwegazi;
• I-calcium D3 - kuyadingeka ukubheka ukugcwala kwe-calcium emzimbeni wesiguli.

Umkhiqizi

Umkhiqizo ukhishwa yinkampani yezemithi yaseCzech i-Zentiva.

Ama-Analog

Izidakamizwa ezifanayo yilezi:

1. I-Lorista isidakamizwa esisetshenziswa njenge-angiotensin 2 antagonist.
2. I-Cozaar ingumuthi ohlose ukwehlisa umfutho wegazi.
3. ILosartan indawo ebizayo yezidakamizwa ezibizayo. Ithuluzi lehlisela umfutho wegazi emazingeni ajwayelekile.
4. I-Presartan yisidakamizwa se-antihypertensive esimisa umfutho wegazi.
5. IBlocktran isidakamizwa saseRussia esisetshenziselwa ukwehluleka kwenhliziyo kanye nomfutho wegazi ophakeme.

IBlocktran isidakamizwa saseRussia esisetshenziselwa ukwehluleka kwenhliziyo kanye nomfutho wegazi ophakeme.

I-Cozaar ingumuthi ohlose ukwehlisa umfutho wegazi.

I-Lorista isidakamizwa esisetshenziswa njenge-angiotensin 2 antagonist.

Imibandela yekhefu lekhemisi

Ikhishwa ngokuqinile ngokuya ngommiselo.

Intengo ye-Lozap Plus

Ukuthengiswa kwezimali kwenziwa ngentengo yama-ruble ayi-300-700.

Izimo zokugcina zomuthi

Umuthi ugcinwa endaweni eyomile futhi emnyama.

Isikhathi sokuphelelwa yisikhathi

Ilungele iminyaka emi-2.

ILoapap Plus iyatholakala ekubhaliseni kuphela.

Ukubuyekezwa ku-Lozap Plus

Izazi zezenhliziyo

U-Evgeny Mikhailovich

Ukutholakala kanye nethuba eliphansi lokuthuthukisa imiphumela emibi kuyizinto eziphambili ze-Lozap Plus. Umuthi unomphumela we-hypotensive kanye nomphumela we-glucosuric. Kodwa-ke, ukusetshenziswa njalo kwesidakamizwa akwanele, ngakho-ke kufanele unikeze ngezimali imali lapho kungekho-hydrochlorothiazide.

UVitaliy Konstantinovich

Ukusetshenziswa kanyekanye kwe-hydrochlorothiazide ene-losartan kuyingxube esebenzayo yezinto ezilungele iziguli eziningi. Kodwa-ke, ekucindezelweni okungaphezulu kwe-160 mm Hg. Ubuciko. kudingeka omunye umuthi onganciphisa amathuba okuba nezinkinga futhi ulondoloze amanani ajwayelekile omfutho wegazi.

Iziguli

U-Irina, oneminyaka engama-53, eMoscow

Kwakufanele ngiphuze umuthi we-Enap isikhathi eside, enganquma ukuwuthenga uwedwa. Ngemuva kokunyuka kwengcindezi okunamandla, waya esibhedlela. Udokotela unqume i-Lozap Plus. Umuthi waphuzwa ekuseni, umphumela uvele ngemuva kwezinsuku ezintathu. Impahla ye-diuretic nayo isize, ngoba kwakukhona ukuvuvukala, kepha ngenxa yomuthi bayancipha.

U-Elena, oneminyaka engama-47, uKemerovo

Ngosizo lweLozap Plus ngiphathwe iminyaka engaba mi-5. Ngalesi sikhathi, kwakungekho umlutha wekhambi, ngakho-ke umuthi uyaqhubeka nokusiza. Ingcindezi ihlala ijwayelekile kulo lonke ntambama, ngakho-ke ngiphuza umuthi amahlandla ama-2 ngosuku. Imiphumela emibi ayenzekanga, okuyinto iphuzu elibalulekile ku-arterial hypertension.

U-Olga, oneminyaka engama-54, uRostov

Uma ngabe laligciniwe ku-edema ngosizo lwezitshalo zokwelapha elinempahla ye-diuretic, khona-ke akunakwenzeka ukwehlisa umfutho ophakeme ngaphandle kwezidakamizwa. Isibhedlela sincome ukuthatha i-Lozap Plus. Ithuluzi alishigi, kepha liyasebenza, ngoba linganciphisa ingcindezi ka-210/110 lifinyelele ezingeni elamukelekayo.