Ukwelashwa kwezifo ezithathelanayo ngaphandle kwemithi elwa namagciwane. Ama-Microorganisms angadala ukumelana nomuthi, ngakho-ke umuthi olwa namagciwane kumele ukwazi ukulwa nale ndawo yamagciwane. I-Ciprinol yi-ejenti ephumelelayo enezinhlobonhlobo zemiphumela.
Igama Lezwe elingafanele
INN - Ciprofloxacin.
Uhlobo lwethebhulethi lomuthi luqukethe i-500, 750 noma 250 mg yento esebenzayo.
Ath
Ikhodi ye-ATX yi-J01MA02.
Khipha amafomu nokwakheka
Amaphilisi
Uhlobo lwethebhulethi lomuthi luqukethe i-500, 750 noma 250 mg yento esebenzayo, esetshenziswa njenge-ciprofloxacin hydrochloride monohydrate. Izici zesimo esingeziwe yilezi:
- I-MCC;
- i-magnesium stearate;
- titanium dioxide;
- i-silicon dioxide;
- i-talc;
- propylene glycol;
- isitashi se-sodium carboxymethyl;
- i-E468 eyengezayo;
- i-povidone.
Umuthi uyasebenza ngokulwa nokutheleleka kwe-streptococcal, amanye ama-chlamydia, i-mycoplasma, i-legionella, i-mycobacteria ne-enterococci.
Isixazululo
Umuthi olwa namagciwane ngendlela yesisombululo uwuketshezi obala nge-tint ephuzi-luhlaza. I-Ciprofloxacin lactate iyinto esebenzayo. Izakhi ezilandelayo zinenani elisizayo:
- usawoti we-lactic acid sodium;
- amanzi ahlanziwe;
- i-hydrochloric acid;
- i-sodium chloride.
Gxila
Umuthi futhi ukhiqizwa ngesimo sokugxiliswa okuhloswe ukwenziwa kwekhambi. Isakhi esiyinhloko yi-ciprofloxacin.
Isenzo se-Pharmacological
Ithuluzi libhekisela ku-fluoroquinolones. Inomphumela we-bactericidal.
Ukuzwela okuphezulu kwesidakamizwa kunamagciwane amaningi angenayo i-gram-negative.
Futhi, umuthi uyasebenza ngokumelene nokutheleleka kwe-streptococcal, ezinye izinhlobo zama-chlamydia, mycoplasma, i-legionella, i-mycobacteria ne-enterococci.
I-antibiotic noma cha
Lapho uthatha umuthi, ukukhiqizwa kwe-enzyme topoisomerase 2, edingekayo ekuhlukanisweni kwamaseli wamagciwane, kuyacindezelwa. Ngakho-ke, umuthi uyigciwane elwa namagciwane, ngoba Amagciwane ayayeka ukukhula futhi afe.
I-Pharmacokinetics
Izici ze-pharmacokinetic zomuthi zibonakaliswa yizici ezilandelayo:
- Ukungena emzimbeni wamanzi;
- ukusatshalaliswa kuzo zonke izicubu;
- bioavailability ka-70-80%;
- ukumuncwa okusheshayo okuvela emgodini wokugaya ukudla.
Umuthi i-Cipronol yi-antibiotic, ngoba Amagciwane ayayeka ukukhula futhi afe.
Kumele kuqashelwe ukuthi ukudla kancane kuthinta izinga lokufakwa kwalo muthi.
Okusizayo
Umuthi uhloselwe ukuqeda i-pathologies elandelayo:
- i-bronchitis eyingozi futhi engamahlalakhona;
- izifo zesikhumba ezingavuvukalanga ezine-etiology yamagciwane;
- ukutheleleka kwezono, kufaka phakathi i-sinusitis ne-frontal sinusitis;
- inyumoniya;
- amagciwane e-otitis media;
- i-prostatitis;
- phlegmon;
- sepsis;
- cholecystitis;
- i-peritonitis;
- urethritis;
- i-mastoiditis;
- chlamydia;
- isifo samathambo septic;
- cholangitis;
- i-gonorrhea;
- isifo sohudo
- ukutheleleka ngemuva kokuhlinzwa;
- i-cystic fibrosis;
- i-salpingitis.
Contraindication
Ithuluzi alisetshenziselwa i-hypersensitivity ezingxenyeni ze-antibiotic neminye imithi ehlobene ne-fluoroquinolones.
Ngokunakekela
Umuthi umuthi wenzeka ngokuqapha ezimweni lapho isiguli sinezinkinga nezifo ezilandelayo:
- ukuphazamiseka kwengqondo;
- isithuthwane
- ukwehluleka kwesibindi;
- ushintsho lwe-pathological ekujuleni kwegazi le-cerebral;
- ukwehluleka kwezinso;
- ukusweleka kwe-glucose-6-phosphate dehydrogenase;
- i-cerebral arteriosulinosis.
Umuthi umuthi wenzeka ngokuqapha ezimweni lapho isiguli sinokuhluleka kwesibindi.
Ungayithatha kanjani i-Ciprinol
Amacwecwe nesisombululo sokuphathwa kwe-intravenous asetshenziswa izikhathi ezi-2 ngosuku.
Ifomu lethebhulethi le-Ciprinol kufanele lihlanzwe ngenani le-fluid eliningi.
Umthamo womuthi obekiwe uhambisana nesimo sesiguli kanye nenkambo yesifo:
- izinhlobo ezimnene ze-pathologies zendlela yokuphefumula nezitho zohlelo lokuchama - 250 mg ngasikhathi;
- ukuthuthukiswa okunamandla kwesifo sokuvuvukala noma ukungezwa kwezinkinga - 500-750 mg.
Ukuze uvikele imiphumela emibi yokuhlinzwa, kunqunywe i-200-400 mg yesidakamizwa ihora eli-1 ngaphambi kokuhlinzwa.
Ngoshukela
Umuthi olwa ne-antibacterial usetshenziswa ngokuqapha, ohambisana nengozi yokuthuthukisa isenzo se-glibenclamide noma ezinye izidakamizwa ze-hypoglycemic. Lokhu kuzoholela ekwehleni okubukhali koshukela wegazi.
Ngoshukela, umuthi usetshenziswa ngokuqapha.
Imiphumela emibi
Amapheshana wesisu
Imiyalo esetshenzisiwe ikhombisa ukuthi izimpawu zokungasebenzi kahle ohlelweni lokugaya ukudla yilezi:
- isicanucanu
- umsebenzi owengeziwe wama-enzyme wesibindi;
- Ubuhlungu esiswini;
- isihlalo sokucasuka;
- ukuhlanza
- uhlobo lwe-colitis pseudomembranous.
Eminye yemiphumela emibi yesidakamizwa ephuma emgodini wesisu ukuhlanza.
Izitho zeHematopoietic
Ukuphendula okungalungile kuthinta uhlelo lwe-hematopoietic, ngenxa yalokho kube nezimpawu:
- ushintsho ekubalweni kweplatelet;
- ukwehla kwenani lamaseli amhlophe egazi;
- i-eosinophilia;
- ukunciphisa kwe-granulocyte.
Isistimu yezinzwa ephakathi
Isimo sesiguli sibonisa ukubonakaliswa okulandelayo:
- ukukhathala
- ukwehluleka
- amaphupho amabi;
- ukuqwasha noma ukozela;
- imibono;
- isiyezi
- ukungaboni kahle
- ikhanda.
Omunye wemiphumela emibi yesidakamizwa ohlelweni lwezinzwa kungaba ukulahlekelwa ukwazi.
Kusuka ohlelweni lomchamo
Imiphumela emibi ethinta uhlelo lomchamo imelelwa yizimpawu:
- i-serum ephezulu ye-serum;
- ukulimala kwe-glomeruli yezinso;
- ukwakhiwa kwamakristalu kasawoti emchameni noma ukuba khona kwamaphrotheni e-Whey negazi kuwo;
- ukukhuphuka kwenani lomchamo nsuku zonke;
- Izinkinga ngenqubo yokuchama.
Kusuka kwizitho zemizwa
Izimpawu eziseceleni ezilandelayo ziyavela:
- i-tinnitus eyenzeka ngezikhathi ezithile;
- izinkinga zokuzwa;
- ukwanda komqondo wokuhogela;
- ukungaboni kahle
Engxenyeni yezitho zemizwa, njengomphumela wecala, ukwehla kombono kungenzeka.
Kusuka ohlelweni lwe-musculoskeletal
Izimpawu ezilandelayo zokusabela okuvela ngaphandle kungavela ezigulini:
- Ubuhlungu bemisipha
- tenosynovitis;
- ukungakhululeki emalungeni;
- isifo samathambo;
- ukuqhuma kwe-tendon.
Kusuka ohlelweni lwezinhliziyo
Ukwephulwa kokusebenza kwezitho zesistimu yenhliziyo kuholela kwizimpawu ezifanayo:
- ukucindezela kwehla;
- ukukhuphuka kwenhliziyo;
- ukufiphala kobuso;
- izinkinga zesigqi senhliziyo.
Umphumela wecala we-Cipronol kungaba ukwephula isigqi senhliziyo.
Allergies
Ukuphendula komzimba kumelwa yizibonakaliso ezilandelayo:
- erythema nodosum;
- i-vasculitis;
- umkhuhlane wemvelo yokwelapha;
- amanxeba ebusweni besikhumba;
- ukulunywa
- ukuphefumula okuncane;
- umkhuhlane we-nettle.
Umuthi ungadala ukusabela okuhlukahlukene komzimba.
Imiyalo ekhethekile
Inkambo yokwelashwa ikhethiwe kucatshangelwa isisindo somzimba nobudala.
Ukuhambisana notshwala
Ukuhambisana kwe-Ciprinol nemikhiqizo yotshwala akulungile, ngakho-ke kuyenqatshelwa ukuphuza utshwala ngesikhathi sokusebenzisa i-antibiotic.
Umthelela ekhonweni lokulawula izindlela
Umuthi uyakwazi ukuthonya ukuphathwa kwezokuthutha. Kuyadingeka ukuyeka ukushayela ngesikhathi sokwelashwa.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ingxenye esebenzayo ingachazwa ubisi lwebele futhi yeqe umgoqo we-placental. Ngenxa yalesi sizathu, umuthi uphambaniswe ukuze usetshenziswe ngesikhathi sokukhulelwa nokukhishwa komzimba.
Umuthi uphambaniswe ukuze usetshenziswe ngesikhathi sokukhulelwa nokukhishwa komzimba.
Kunquma i-Ciprinol ezinganeni
Iminyaka engaphansi kweminyaka eyi-18 kuwukwephula umthetho, kepha kukhona okuhlukile:
- isidingo sokuvimbela nokuqeda i-anthrax;
- ukuba khona kwe-pulmonary cystic fibrosis ezinganeni ezineminyaka emi-5 kuya kwengama-17;
- ukuthuthukiswa kwezinkinga ezibangelwa umsebenzi wePseudomonas aeruginosa.
Sebenzisa ebudaleni
Abantu asebekhulile banqunywa ngokuqapha.
Isicelo sokusebenza kokulimala kwezinso
Kuyadingeka ukukhetha umthamo owenele.
Uma kwenzeka umsebenzi wezinso ongasebenzi kahle, kubalulekile ukukhetha umthamo ofanele.
Sebenzisa umsebenzi wesibindi okhubazekile
Ngokuhluleka kwezinso, sebenzisa ngokuqapha. Inkambo yokwelapha ikhethwa ngawodwana.
Ukweqisa
Ukusetshenziswa kwomuthi kumithamo engamukeleki kubangela ukuvela kwalezi zimpawu:
- isicanucanu
- ikhanda;
- ukuthuthumela
- imibono;
- ukungazi kahle;
- isifo sohudo
- ukuhlanza
- iminyakazo.
Isiguli kufanele siyiswe esikhungweni sezokwelashwa ukuze sisizwe.
Ukuxhumana nezinye izidakamizwa
Umuthi ungahlanganiswa nalawa makhambi alwa namagciwane:
- IVancomycin;
- Meslocillin;
- Azlocillin;
- Ceftazidime.
I-Ciprinol inezinye izici zokusebenzelana kwezidakamizwa:
- Imithi ye-antacid kanye nama-ejenti ane-magnesium, i-iron, i-zinc, i-aluminium - ithinta kabi izinga lokufakwa kwento esebenzayo;
- I-Theophylline - ikhulisa amathuba emiphumela emibi;
- I-Warfarin - ubungozi bokuphuma kwegazi bukhuphuka;
- I-Didanosine - ukumuncwa kwento esebenzayo ye-Ciprinol kuya ngokubi;
- izixazululo ze-sodium chloride, i-dextrose ne-fructose ziyahambelana nomuthi.
Ngokuphathwa kanyekanye kwe-Cipronol neWarfarin, ubungozi bokopha buyanda.
Ama-Analog
Izidakamizwa ezilandelanayo ze-antibacterial zinezindawo ezifanayo:
- UCyprolet;
- Iqiniso;
- I-Syphlox;
- Norfacin;
- UTsiprovin;
- UCyproquin;
- I-Tariferide;
- I-Leflobact;
- Lefoksin;
- I-Lomefloxacin;
- I-Ofloxacin;
- Gatifloxacin.
Umuthi awusatshalaliswa ngaphandle kokuthola umuthi.
Imibandela yekhefu lekhemisi
Kuthengiswa ngomuthi.
Ngingakwazi ukuthenga ngaphandle kadokotela
Akuhanjiswa ngaphandle kwencwadi kadokotela.
Intengo ye-Ciprinol
Kuthengiswe ngenani lama-ruble angama-45-115.
Izimo zokugcina zomuthi
Gwema kude nemisebe yelanga eqondile kanye nomswakama ophezulu.
Isikhathi sokuphelelwa yisikhathi
Isikhathi sokugcina - iminyaka emi-5.
Umkhiqizi
Umuthi lo ukhiqizwa yinkampani yezokwelapha yaseSlovenia i-KRKA.
Ukubuyekezwa ku-Ciprinol
Odokotela
USergey Pavlovich, udokotela wezifo ezithathelwanayo
Amagciwane amaningi azwela i-ciprinol, ngakho-ke umuthi ufanele ukwelashwa izifo eziningi. Umuthi ubonakala nge-bioavailability ephezulu nokungena ngokushesha kwezicubu zomuntu. Lokhu kuholela ekuqaleni komphumela wokwelapha.
UDenis Vadimovich, udokotela ojwayelekile
Umuthi uhambisana kahle nemithi ethile elwa namagciwane, ongaqhakambisa ngayo umphumela wegciwane lesidakamizwa. Kodwa-ke, kufanele kuqashelwe ekuphatheni i-Ciprinol, njengoba ukungasebenzi kahle kwezitho zomzimba kuvimbela noma kuvimbela ukusetshenziswa komuthi.
Lapho uthatha i-Ciprinol ngendlela yamathebulethi, kuyadingeka ukuwaphuza ngenani elikhulu loketshezi.
Iziguli
U-Alena, oneminyaka engama-34, uKazan
Uye esibhedlela enesifo sokulimala kwesikhumba, lapho afike wenza khona izivivinyo waya ewadini. Njengokwelashwa, kunqunywa i-Ciprinol. Umuthi wanikezwa izinsuku ezingama-5, kepha awuzange ube ngcono. Ngezikhathi ezithile, isicanucanu nesiyezi, kwesinye isikhathi kwakuvela ikhanda. Ngatshela udokotela ngakho. Waphendula wathi ukusabela okunjalo kwakuqabukela. Akusekho isifiso sokuthatha isidakamizwa esinje.
U-Elena, oneminyaka engama-29, u-Ufa
Ngosizo lwe-Ciprinol, saqeda izinkinga ezibangelwa umkhuhlane. Ukwelashwa kwaba yimpumelelo. Ngemuva kwezinsuku ezintathu, umkhuhlane wehla, ngolunye usuku kamuva izinhlungu endlebeni nasendaweni yesifuba zanyamalala. Ukwelashwa kwakwanele ukuthenga iphakethe elilodwa le-antibiotic.
U-Olga, oneminyaka engama-34, uTambov
Ngonyaka odlule ngaya esibhedlela nginezindlala. Ngize nezingubo, imikhiqizo yokuhlanzeka kwabesifazane, ilaptop - futhi ngokushesha ngizokwelashwa. Ukhethe ukusetshenziswa kwe-ciprinol. Umuthi lo wawungeniswa emithanjeni amahlandla ama-2 ngosuku. Kwakungemnandi ngesikhathi somjovo, kepha lokhu kwakuwukuphela kophawu okwakufanele lubekezelelwe. Izimpawu ezingekho azange zivele, futhi umphumela waba mnandi. Umuzwa wokuthi lesi sifo asikaze sibe khona.
