Ezigulini ezinalolu hlobo sikashukela, umzimba awukwazi ngokwemvelo ukugcina izinga elijwayelekile likashukela egazini. Kungakho kufanele balinganise ushukela kaningana nsuku zonke futhi bafake imithamo ye-insulin ngokwabo. Ukuzithiba kufanele kube okuqinile kakhulu. Ukuphumula okuncane noma ukwengamela kungabiza kakhulu impilo yesifo sikashukela.
Ngokufanelekile, isifo sikashukela singalashwa ngokufaka amaseli ama-islet abhubhisiwe. Odokotela bababiza ngeziqhingi zeLangerhans. Ngokwesisindo, la maseli emanyikweni enza i-2% kuphela. Kepha kungumsebenzi wabo obaluleke kakhulu emzimbeni. Imizamo eminingi yososayensi yokuhambisa iziqhingi zaseLangerhans yaphumelela ngaphambili. Inkinga ukuthi isiguli kwakudingeka ukuthi "siboshwe" isikhathi eside sokuphathwa kwama-immunosuppressants.
Ubuchwepheshe obukhethekile bokufakelwa manje sebenziwe. Umongo wayo ukuthi i-capsule ekhethekile ikuvumela ukuba wenze iseli elinikelayo "lingabonakali" emasosheni omzimba. Ngakho-ke akukho ukwenqatshwa. Futhi isifo sikashukela siyanyamalala ngemuva kwezinyanga eziyisithupha. Isikhathi sesifikile sokuvivinywa kwenqwaba yezempilo. Kufanele bakhombise ukusebenza kwendlela entsha. Isintu sinethuba langempela lokunqoba isifo sikashukela.
