IZINGA LOKWEHLISA CHOLESTEROL KUSHUKELA - IZINDLELA NEZINDLELA ZOKWELASHWA

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I-cholesterol iyinto ekhethekile. Ngamanani amancane, ayasiza, futhi ngamanani amakhulu ayingozi emzimbeni.

Lokhu kuhlanganiswa kwamakhemikhali wemvelo kuyadingeka ekwenziweni kwama-hormone besifazane nabesilisa, kuqinisekiswe izinga lamanzi elijwayelekile emangqamuzaneni omzimba. Kunezinye izici.

Kodwa i-cholesterol eyeqile iholela kwisifo esibi - isifo sokuqina kwemithambo yegazi. Kulokhu, umsebenzi ojwayelekile wemithambo yegazi uyaphazamiseka. Imiphumela ingaba mibi kakhulu.

Statins - ama-cholesterol Fighters

I-pharmacology yanamuhla inikeza isigaba sonke semithi, enye yezinhloso zazo ukwehlisa i-cholesterol yegazi. Le mishanguzo ibizwa ngokubizwa ama-statin.

Isenzo sama-statins yindlela eyinkimbinkimbi equkethe izinqubo eziningi. Umphumela ubalulekile lapha:

ukuncipha kokukhiqizwa kwe-cholesterol yesibindi;
kunciphise ukungena kwamathumbu kwe-cholesterol ekudleni;
Ukuqedwa kwendlebe kwakha ama-cholesterol plaque emithanjeni yegazi.

Izinkomba eziphambili zama-statin yilezi:

isifo sokuqina kwemizwa;
isifo senhliziyo, usongo lokuhlaselwa yisifo senhliziyo;
ku-mellitus yesifo sikashukela - ukuvimbela noma ukunciphisa izinkinga ezihambisana nokuhamba kwegazi.

Kwezinye izimo, ama-atherosselotic plaque angakha ngisho ne-cholesterol ephansi. Futhi uma lesi sici sitholakala esigulini, ama-statin nawo anganqunyelwa.

Izimo zesifo sikashukela

Isici esibonakalayo sesifo sikashukela inani elikhulu lezifo ezifanayo.

Ziyavela lapho ukudla, izinhlobo zomuthi zingalandelwa, futhi isiguli ngokuvamile asinandaba ngesimo sakhe. Izifo zenhliziyo nezemithambo ziyinkinga enkulu yesifo sikashukela.

Ngokwezibalo ezithile, ubungozi bokuhlaselwa yisifo senhliziyo, isifo sohlangothi kanye nezinye izifo ezithile kubantu abanesifo sikashukela siphindwe kane kuya kweziyishumi (uma siqhathaniswa nalabo abangenaso isifo sikashukela). Izibalo ezifanayo ziyakhombisa: ngokuqala kokwehla kwesifo, ukufa kwabantu phakathi kwesifo sikashukela kungama-3.1%. Nge-infyoction ye-myocardial - kakade i-54.7%.

Awukwazi ukwelapha isifo sikashukela. Kepha kungenzeka ukwandisa isikhathi kanye nekhwalithi yempilo yesifo sikashukela ukuze lesi sifo sibe yinto eqondisayo kuphela, hhayi umusho. Uma ngasikhathi sinye kungenzeka ukuthi kuthuthukiswe i- metabolism yamafutha, ehambisana kakhulu nezinkinga ze-cholesterol ephezulu, khona-ke singakhuluma ngempumelelo enkulu. Lokhu kubaluleke kakhulu ngohlobo lwesibili lwesifo. Kungenxa yalokhu ukuthi i-lipid (fat) metabolism iphazamiseka kakhulu.

Manje odokotela abaningi babheka ukwelashwa okwehlisa i-lipid kwesifo sikashukela sohlobo II kucishe kubaluleke njengokusetshenziswa kwama-hypoglycemic agents. Nayi imbali yokusebenzisa ama-statins kushukela. Kwezinye izimo, le mishanguzo inqunywa ngisho ne-cholesterol ejwayelekile - ukuvimbela i-atherosclerosis.

Khetha ukunambitheka?

Awungekhe ukhethe isidakamizwa esigabeni sama-statin engqondweni yakho!

Imithi yaleli qembu yehlukile ngokwakhiwa, umthamo, imiphumela emibi. Lezi zokugcina zinenqwaba yama-statin, ngakho-ke ukwelashwa kufanele kubhekwe ngodokotela.

Cabanga ngezidakamizwa ezithile.

ILovastatin - Lokhu kungumuthi otholakala ekubumbeni ngokubola.
I-analogue yalesi sidakamizwa simvastatin.
Kusondele kakhulu kulezi zidakamizwa ezimbili kucatshangelwa pravastatin.
Rosuvastatin, atorvastatin futhi fluvastatin - Lezi izidakamizwa zokwenziwa ngokuphelele.

I-Rosuvastatin manje isabhekwa njengomphathi werekhodi ngempumelelo yokunciphisa cholesterol. Ngokuya kocwaningo oluthile, emasontweni ayisithupha okusetshenziswa, izinga le-cholesterol lehle ngo-45-55% uma liqhathaniswa nezinkomba zokuqala. IPravastatin kulokhu ingenye yezindawo zokugcina, banciphisa i-cholesterol ngo-20-34%.

Amanani weStatin angahluka kakhulu ngokuya ngomkhiqizi, inqubomgomo yezimali yekhemisi ethengiswayo, futhi nangesifunda. Kwezinye izimo, intengo ye-simvastatin ayifinyeleli kuma-ruble ayikhulu kumathebulethi angama-30. Uhla olubanzi kakhulu lwamanani ama-rosuvastatin: ama-ruble angama-300-700. Ukunikezwa kwezidakamizwa ezisezingeni eliphakeme zama-statin kuncike ezinhlelweni zenhlalo zesifunda esithile kanye nesimo sesifo sikashukela uqobo.

Isikhathi sokwelashwa

Umphumela othile wokuthatha ama-statins ubonwa ngemuva kwenyanga yokuthatha.

Ukuphazamiseka kwe-metabolism yamafutha - lokhu akuyona ikhanda elibuhlungu, lapha amaphilisi ambalwa awakwazi ukukwenza. Umphumela omuhle oqondile kwesinye isikhathi ungavela kuphela emva kweminyaka emihlanu. Ngemuva kokuhoxiswa kwezidakamizwa, ngokushesha emuva kwalokho kubuye kubuye kubuywe: i-fat metabolism iphinde iphazamiseke.

Ngokubheka izici eziningana (kufaka phakathi ama-contraindication), abanye odokotela bangase banikeze ama-statins ezimweni ezithile kuphela. Isibonelo, lapho umuntu onesifo sikashukela esivele enemiphumela emibi yokuphazamiseka kwe-lipid metabolism noma ingozi yangempela yokuhlakulela isifo sokuqina kwezinzwa kanye nezinkinga ezalandela.