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Isifo sikashukela sohlobo 1 senziwa lapho i-insulin ingasebenzi egazini lomuntu. Ngenxa yalokhu, ushukela awangeni ezingubeni nasemangqamuzaneni (i-insulin ingumqhubi, kusiza amangqamuzana eglucose ukungena ezindongeni zemithambo yegazi).
Kuvela isimo esibuhlungu emzimbeni: amangqamuzana ayalamba futhi awakwazi ukuthola ushukela, nemithambo yegazi ibhujiswa ushukela omningi ngaphakathi.
Ngemuva kwesistimu yemithambo yegazi, zonke izitho zomuntu zibhujiswa kancane futhi ngokuzethemba: izinso, inhliziyo, amehlo, isibindi kanye ne-gangrene eyomile yemikhawulo yakhiwa. Ake sichaze kabanzi ukuthi uhlobo lokuqala lwesifo sikashukela lubonakala kanjani ezithweni ezahlukahlukene zomzimba womuntu, futhi yiziphi izingqinamba ezakhiwa ngesifo sikashukela?
Kungani ushukela ophakeme mubi?
Iziguli ezinesifo sikashukela sohlobo lokuqala ziphoqelelwa ukuba zibalwe nsuku zonke izindlela zokudla okunomsoco we-carbohydrate, zikala amazinga kashukela futhi zithathe i-insulin. Kodwa-ke, kunzima ukufaka esikhundleni sokulungiswa okuhle komzimba ngokubala kwakho. Kukhona amathuba aphezulu wethamo elinganele le-insulin ngokweqile kwama-carbohydrate ekudleni. Ngakho-ke, kushukela, ushukela luqongelela egazini lomuntu.
Ushukela omkhulu ubangela ukoma. Umuntu womile ngaso sonke isikhathi, ukunxusa ukuthi uchame kuba njalo, buthakathaka buvele. Lokhu kungukubonakaliswa kwangaphandle kwesifo. Izinkinga zangaphakathi zikhulu kakhulu futhi ziyingozi kakhulu. Bakha ngesilinganiso sikashukela esingaphakeme.
Noma inani le-glucose lidlula kancane okwejwayelekile (ngaphezu kwe-5.5 mmol / L esiswini esingenalutho), kukhona ukubhujiswa okuhamba kancane kwemithambo yegazi nezinye izitho zomzimba.
Zakhiwa kanjani izinkinga?
Izinkinga zesifo sikashukela sohlobo 1 ngokuyinhloko zithinta uhlelo lokujikeleza kwegazi.
Ngenxa yokuqukethwe okushibhile kwe-glucose, imithambo yegazi iba muhle kakhulu, ukuthambekela kokwenza izingqimba zegazi kuyanda, ifomu lokufaka imali ezindongeni zemithambo yegazi (atherosclerosis). Igazi liba yinto ebonakalayo futhi ibe mnene.
Njengomphumela wokuphazamiseka kwegazi lokugeleza, kukhiqizwa okunganele kwezitho ezinezinto ezibalulekile.
Igazi lidlulisa ama-molecule we-oksijini, ushukela (ukusuka ekuwohlokeni kwe-carbohydrate), ama-amino acid (ukuwohloka kwamaprotheni), amafutha acid (ukuwohloka kwamafutha) kumaseli wezitho ezahlukahlukene. Ngokugeleza kwegazi okuhamba kancane, amaseli athola izinto ezingabalulekile kangako. Ngasikhathi sinye, ukususwa kobuthi kumaseli nakho kubambezela. Lokhu kwakha ukudakwa kwangaphakathi komzimba, kunoshevu ngemikhiqizo yomsebenzi obalulekile wamaseli wayo.
Kulezo zindawo lapho ukugeleza kwegazi kwehliswe khona kancane, kwakheka izehlakalo ezixinzekayo - ukuvuvukala, ukuqina, ukuqubuka, ukuqhekeka. Emzimbeni womuntu ophilayo, kuvela izindawo zokubola necrosis. Ngokuvamile, izinkinga zokujikeleza kwegazi zenzeka emikhawulweni ephansi. I-glucose engancishisiwe ayiguquki ibe amandla ezinto zangaphakathi. Idlula emgodini wegazi futhi yakhishwa yizinso.
Abantu abanesifo sikashukela sohlobo 1 banciphisa isisindo, bazizwe bebuthakathaka, bezela, bekhathala, bezwa ukoma okungapheli, ukuchama kaningi, ikhanda. Kukhona ushintsho ekuziphatheni, ukusabela kwengqondo, ukubukeka kokushintshana kwemizwelo, ukuhlangana kokudangala, ukwethuka, umsindo. Konke lokhu kuphawuleka kweziguli ezithola ukuguquguquka kweglucose egazini. Lesi simo sibizwa isifo sokuqina kwesifo sikashukela.
Isifo sikashukela nezinso
Ngehora, amalitha ayi-6 egazi lomuntu adlula ezinso.
Izinso zingcolile zomzimba womuntu. Ukoma okungapheli okuvela kushukela kudinga ukuphuza uketshezi. Ngenxa yokuthi izinso zinikezwa umsebenzi ngemithwalo ekhuphukayo. Izitho ezivelelayo azihlungi nje igazi elijwayelekile, ziqongelela ushukela ngokwazo.
Lapho inani le-glucose egazini lidlula i-10 mmol / l, izinso ziyeka ukubhekana nemisebenzi yazo yokuhlunga. Ushukela ungena kumchamo. Umchamo omnandi wakheka esigaxeni, lapho ushukela iba yisisekelo sokukhula kwamagciwane we-pathogenic. Ukuvuvukala kwenzeka esinyeni nasezinso - cystitis nephritis. Esithweni sesifo sikashukela, kwenziwa izinguquko ezibizwa ngokuthi yi-diabetesic nephropathy.
Ukuboniswa kwe-nephropathy:
- amaprotheni emchameni
- ukonakala kokuhlunga kwegazi,
- ukwehluleka kwezinso.
Izinkinga zenhliziyo
Phakathi kwezinkinga ezivame kakhulu zesifo sikashukela sohlobo 1 isifo sezinhliziyo ezi-coronary (CHD).
I-IHD iyinkimbinkimbi yezifo zenhliziyo (i-arrhythmia, i-angina pectoris, isifo senhliziyo), ezakhiwa ngokunikezwa komoya ophelele. Lapho imithambo yegazi ivinjelwa, kuvela ukuthi i-myocardial infarction (ukufa kwesicubu senhliziyo).
Abantu abangenaso isifo sikashukela bathola izinhlungu, umuzwa ovuthayo endaweni yesifuba. E-diabetesics, i-myocarditis ingenzeka ngaphandle kobuhlungu, ngoba ukuzwela kwemisipha yenhliziyo kuncishisiwe. Uma kungekho zimpawu zobuhlungu, kunengozi enkulu empilweni yeziguli. Umuntu kungenzeka angazi ukuthi unesifo senhliziyo, angatholi ukwesekelwa izidakamizwa futhi afe ngokungazelelwe ngokuboshwa kwenhliziyo.
Izinkinga eziningi zesifo sikashukela zihambisana nokuqina okukhulu kwemithambo yegazi.
Uma umkhumbi omkhulu ngaphakathi kwenhliziyo ulimele, kuba nokuhlaselwa yinhliziyo (uma umkhumbi kulimele, kuba khona unhlangothi). Yingakho uhlobo lwe-1 sikashukela lukhulula ngokuqinile iziguli ngemivimbo noma ngokushaya kwenhliziyo kumagumbi eziphuthumayo.
Isiguli esithile "inhliziyo yesifo sikashukela" Kukhulise osayizi nokuphazamiseka emsebenzini we-myocardium (izicubu zomzimba ezixhuma igazi).
Izinkinga zamehlo
Ukulimazeka emithanjeni yegazi yezicubu zamehlo kunciphisa umbono, kwakha izinhlungu zomzimba, i-glaucoma, ubumpumputhe.
Lapho imithambo yegazi ichichima igazi, ukuphuma kwesibindi kuhlamvu lwesohlo. Ngaphezu kwalokho, ngesifo sikashukela, ibhali livame ukwakheka esweni, akuvamisile - ukufa okuyingxenye kwezicubu kwenzeka (uma i-beg yegazi ivimbe ukuhamba kwegazi esitsheni).
Ngemuva kweminyaka engama-20 yesifo sikashukela, i-retinopathy itholakala ku-100% yeziguli ezigulayo.
Izinkinga zamehlo zibizwa ngokuthi yi-ophthalmopathy yesifo sikashukela kanye ne-retinopathy. Izimpawu zomtholampilo zezinguquko ze-retinopathic ku-retina - ama-hemorrhages amancane, ama-vasal sacs (aneurysms), i-edema. Umphumela we-retinopathy yesifo sikashukela ukukhipha amandla emzimbeni.
Izinkinga Zemizwa
Ukungondleki okungapheli kokuphela kwezinzwa kuholela ekulahlekelweni kokuzwela, imvamisa kakhulu ezindaweni zokuwohloka okukhulu ekunikezelweni kwegazi - emaphethelweni. Lesi simo sibizwa ngokuthi yi-neuropathy yesifo sikashukela.
Izibonelo ezisebenzayo zalesi simo: isiguli sikashukela sihamba esihlabathini esishisayo futhi sasingazizwa sishiswa izinyawo. Noma akazange aqaphele ukuthi ungena kanjani emeva, ngenxa yalokho i-pus yakheka esilondeni esingalashwa.
Izinkinga zamazinyo
Ukujikeleza kwegazi okungekuhle kuthinta izifo ezithathelwanayo zomgogodla womlomo:
- gingivitis - ukuvuvukala kongqimba lwangaphandle lwezinsini,
- i-periodontitis - ukuvuvukala kwezicubu ezingaphakathi zezinsini,
- amathuba okubola kwamazinyo ayanda.
Isifo sikashukela nemilenze
Ukuphazamiseka okukhulu ekunikezelweni kwegazi kuyabonakala emilenzeni. Kwenziwa izinkinga, olubizwa ngokuthi unyawo lwesifo sikashukela:
- Rash emilenzeni nasezingalweni.
- Imisipha ebuthaka yomlenze iphakamise.
- Ukubhujiswa kwamathambo nokuhlangana konyawo.
Ukuncipha kokuzwela kwezinyawo nemiphumela yento ecasulayo (izinga lokushisa, izinto ezibukhali), ingozi yokuthola ukushiswa, i-hypothermia, ukusika nokulimala kokugwaza.
Imvamisa, unyawo lwesifo sikashukela luphela ngokunqunyulwa umlenze.
Isifo Sikashukela Nokugaya
I-hormone i-insulin, engabunjwanga ngohlobo 1 sikashukela, iyabandakanyeka ekwakhiweni kwejusi yesisu. Ngakho-ke, ngesifo sikashukela, ukwakheka kwejusi lesisu kuncishiswa kakhulu. I-gastritis iyakhiwa, okuyingxaki evamile yesifo sikashukela.
Okunye ukubonakaliswa kwesifo sikashukela ohlelweni lokugaya:
- Isifo sohudo (isifo sohudo) - ngenxa yokugaya ukudla okunganele.
- I-dysbiosis yangaphakathi ngenxa yezifo zokuvuvukala.
- Ukwephulwa kwezinqubo ze-metabolic esibindini. Esimweni sokunganakwa, ukwephulwa okunjalo kuholela ku-cirrhosis.
- Kwehliswe umsebenzi we-gallbladder, kuholele ekukhuleni kosayizi, ukuvuvukala kanye nokwakhiwa kwamatshe.
Isifo sikashukela kanye nokuhlangana
Ukuvuvukala okuhlanganisiwe nakho kwakhiwa ngenxa yokunganele kwegazi. Lokhu kuvezwe ekunciphiseni ukuhamba, izinhlungu, ukuqhekeka lapho ugobile. Kuyinto isifo sikashukela isifo samathambo. Ukhuliswa yi-osteoporosis (ukuvuvukala kwe-calcium emathanjeni ngenxa yokuchama kaningi nokoma okungapheli).
Coma
Isifo sikashukela esiyinkimbinkimbi siyinkinga enkulu yesifo sikashukela.
IComa ivela ngamacala amabili:
- lapho ushukela ukhuphuka kakhulu (ngaphezu kwama-33 mmol / l);
- lapho kwenzeka i-insulin ngokweqile, futhi inani le-glucose egazini lalingathandeki (ngaphansi kuka-1.5 mmol / l).
I-Coma (ukulahlekelwa ukwazi) yenzeka ngemuva kwamahora ayi-12- 24 ngemuva kokuqala kwezimpawu ezisobala zokukhuphuka koshukela (ukoma okunzima, ukuchama okungapheli, ikhanda, isicanucanu nokuhlanza, ubuthakathaka).
Inani elikhulayo likashukela egazini liyingozi ngokuqina kwalo. Ngisho noshukela ophakanyiswe kancane ngokuvezwa njalo kubangela imiphumela engaphenduki. Ukuthuthukiswa kwezinkinga zohlobo lwesifo sikashukela sokuqala kuholela ekukhubazekeni, bese kuthi ekufeni komuntu. Ukuvimbela okuhle kwezinkinga zesifo sikashukela ukuqapha ushukela, ukudla okune-carb ephansi kanye nokusebenza ngokomzimba okungenzeka.
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