I-insulin emfushane yomuntu iqala ukusebenza imizuzu engama-30-45 ngemuva komjovo, kanye nezinhlobo zakamuva ze-ultrashort ze-insulin Humalog, NovoRapid ne-Apidra - ngisho ngokushesha, ngemuva kwemizuzu eyi-10-15. I-Humalog, NovoRapid ne-Apidra abayona i-insulin yabantu, kodwa ama-analogues, okungukuthi, aguquliwe, athuthukiswa uma kuqhathaniswa ne-insulin yomuntu “yangempela”. Ngenxa yefomula yabo ethuthukisiwe, baqala ukwehlisa ushukela wegazi ngokushesha ngemuva kokungena emzimbeni.
Ama-analog e-Ultrashort insulin akhiwe ukuze acindezele ngokushesha ushukela wegazi okwenzeka lapho onesifo sikashukela efuna ukudla ngokushesha ama-carbohydrate. Ngeshwa, lo mbono awusebenzi ekusebenzeni, ngoba ushukela ugxuma emikhiqizweni enqatshelwe efana nokuhlanya. Ngokwethulwa kweHumalog, i-NovoRapid ne-Apidra, sisaqhubeka nokulandela ukudla okune-carbohydrate ephansi. Sisebenzisa ama-analogia e-ultrashort ye-insulin ukwehlisa ushukela ngokushesha ukuze ube okwejwayelekile uma kungagxuma kungazelelwe, futhi ngezikhathi ezithile ezimweni ezikhethekile ngaphambi kokudla, lapho kungakhululeki ukulinda imizuzu engama-40-45 ngaphambi kokudla.
Ukufakwa kwama-insulin amafushane noma e-ultrashort ngaphambi kokudla kuyadingeka kwiziguli ezinesifo sikashukela sohlobo 1 noma uhlobo 2, ezinoshukela wegazi ophezulu ngemuva kokudla. Kucatshangwa ukuthi usuvele ulandela ukudla okune-carbohydrate ephansi, futhi uke wazama namaphilisi kashukela kababili, kepha zonke lezi zindlela zisize kuphela ngokwengxenye. Funda mayelana nesifo sikashukela sohlobo 2 futhi uthayiphe ushukela ongu-1. Njengomthetho, kunengqondo ukuthi iziguli ezinesifo sikashukela sohlobo 2 zizama ukwelashwa kuphela nge-insulin eyengeziwe, njengoba kuchazwe esihlokweni esithi “I-insulin Lantus ne-Glargin enwetshiwe. I-Medium NPH-Insulin Protafan. " Mhlawumbe ama-pancreas akho kusuka ku-insulin ende ayohlala kahle futhi aqongele phezulu kangangokuba angakwazi ukuqeda ukugxuma kushukela wegazi ngemuva kokudla, ngaphandle kwemijovo eyengeziwe ye-insulin ngaphambi kokudla.
Kunoma yikuphi, isinqumo sokugcina sokuthi i-insulin kufanele ilusebenzise kuphi, ngamahora amangaki nokuthi imiphi imithamo, ithathwa kuphela yimiphumela yokuzihlola ngokuphelele ushukela wegazi okungenani izinsuku eziyi-7. Uhlobo olusebenzayo lokwelashwa kwe-insulin lungaba umuntu ngamunye. Ukuyiqamba, udokotela kanye nesiguli uqobo kudingeka bazame okungaphezu kokubhala bonke abantu abanesifo sikashukela ukuqashwa okufanayo kwemijovo engu-1-2 yemithamo ye-insulin ngosuku. Sincoma ukuthi ufunde i-athikili ethi “Hlobo luni lwe-insulin okufanele ulujove, ngasiphi isikhathi nokuthi yikuphi okuthe dosi. Izikimu zesifo sikashukela sohlobo 1 nohlobo 2 sikashukela. ”
Ungaselapha kanjani isifo sikashukela nge-insulin emfushane noma ye-Ultra iDemo
I-Ultrashort insulin iqala ukusebenza ngaphambi kokuba umzimba ube nesikhathi sokuthatha amaprotheni bese iguqula amanye awo abe ushukela. Ngakho-ke, uma uku-ekudleni okuphansi kwe-carbohydrate, i-insulin emfushane ingcono ngaphambi kokudla kuneHumalog, NovoRapid noma i-Apidra. I-insulin emfushane kufanele inikezwe imizuzu engama-45 ngaphambi kokudla. Lesi isikhathi esilinganiswayo, futhi isiguli ngasinye esinesifo sikashukela sidinga ukusicacisela yena uqobo. Ungayenza kanjani, funda lapha. Isenzo sezinhlobo ezisheshayo ze-insulin sithatha cishe amahora angama-5. Yiso kanye isikhathi abantu abavame ukusidingida sokugaya ngokugcwele ukudla abakudlayo.
Sisebenzisa i-insulin esebenzisa i-ultrashort insulin ezimeni "eziphuthumayo" ukuze kwehliswe ushukela wegazi ngokushesha ube yinto evamile uma igxuma kungazelelwe. Izinkinga zesifo sikashukela zanda ngenkathi ushukela wegazi ugcinwa uphakeme. Ngakho-ke, sizama ukwehlisa kube okujwayelekile ngokushesha okukhulu, futhi kulokhu i-insulin efushane ebomvu ingcono kune mfushane. Uma unesifo sikashukela sohlobo 2 esibuthakathaka, okusho ukuthi, ushukela ophakanyisiwe usheshe uvame ngokwawo, awudingi ukujova i-insulin eyengeziwe ukuze wehlise. Ukulawulwa okuphelele kukashukela izinsuku eziningana ezilandelanayo kusiza ukuqonda ukuthi ushukela wegazi uziphatha kanjani esigulini esinesifo sikashukela.
Izinhlobo ze-insulin ezimfishane - zisebenza ngokushesha kunanoma ngubani
Izinhlobo ze-Ultrashort ze-insulin yiHumalog (Lizpro), iNovoRapid (Aspart) ne-Apidra (Glulizin). Akhiqizwa yizinkampani ezintathu zemithi eziqhudelanayo. I-insulin emfushane ejwayelekile ingeyomuntu, futhi i-ultrashort - lezi yizimpawu, i.e., eziguquliwe, ezithuthukisiwe, uma ziqhathaniswa ne-insulin yangempela yomuntu. Ukuthuthuka kulele ekutheni baqala ukwehlisa ushukela wegazi ngokushesha ngisho kunale ndlela emifushane ejwayelekile - imizuzu emi-5-15 ngemuva komjovo.
I-Ultrashort insulin analogue yasungulwa ukunciphisa ijubane loshukela wegazi lapho onesifo sikashukela efuna ukudla ngokushesha ama-carbohydrate. Ngeshwa, lo mbono awusebenzi ekusebenzeni. Ama-carbohydrate, adonswa ngokushesha, asaluphakamisa ushukela wegazi ngokushesha ukwedlula ngisho ne-insulin efingqiwe yakamuva kakhulu ukuze wehlise. Ngokwethulwa kwalezi zinhlobo ezintsha ze-insulin emakethe, akekho oye wasula isidingo sokulandela ukudla kwe-carbohydrate ephansi futhi unamathela ngendlela yemithwalo emincane. Vele, udinga ukulandela irejimeni kuphela uma ufuna ukulawula kahle isifo sikashukela futhi ugweme izinkinga zaso.
Uma ulandela ukudla okune-carbohydrate ephansi yohlobo 1 noma isifo sikashukela 2, khona-ke i-insulin emfushane yomuntu ungcono ngemijovo ngaphambi kokudla kunabalingani bakho be-ultra-short. Ngoba ezigulini ezinesifo sikashukela esidla ama-carbohydrate amancane, umzimba uqala ugaye amaprotheni, bese uguqula ezinye zazo zibe ushukela. Le yinqubo ehamba kancane, futhi i-insulin ye-ultrashort iqala ukusebenza ngokushesha okukhulu. Izinhlobo ezimfishane ze-insulin - kunjalo nje. Ngokuvamile kudingeka ukuthi kugawulwe imizuzu engama-40-45 ngaphambi kwesidlo esine-carbohydrate ephansi.
Kodwa-ke, kwiziguli ezinesifo sikashukela ezivimbela ama-carbohydrate ekudleni kwazo, ama-analog e-ultrashort insulin nawo angaba usizo. Uma ulinganise ushukela wakho nge-glucometer futhi uthole ukuthi wagxuma, khona-ke i-insulin emfishane emfushane iyokwehlisa ngokushesha kunokuba mfushane. Lokhu kusho ukuthi izinkinga zesifo sikashukela zizoba nesikhathi esincane sokukhula. Ungafaka futhi insulin ye-ultrashort, uma singekho isikhathi sokulinda imizuzu engama-45 ngaphambi kokudla. Lokhu kuyadingeka endaweni yokudlela noma ohambweni.
Ukunaka! Ama-insulin ama-Ultrashort anamandla amakhulu kunamfishane. Ngokuqondile, i-1 unit yeHumalog izokwehlisa ushukela wegazi cishe izikhathi ezingama-2,5 ngaphezulu kwe-1 unit ye-insulin emfushane. I-NovoRapid ne-Apidra cishe izikhathi ezi-1.5 zinamandla kune-insulin emfushane. Lesi isilinganiso esilinganisiwe, futhi kuzo zonke iziguli ezinesifo sikashukela kufanele sizisungulele lona ngecala nangephutha. Ngokuvumelana nalokho, imithamo ye-ultrashort insulin analog kufanele ibe ngaphansi kakhulu kunemithamo efanayo ye-insulin emfushane yomuntu. Futhi, ucwaningo lukhombisa ukuthi uHumalog uqala ukusebenza imizuzu engu-5 ngokushesha kuneNovoRapid ne-Apidra.
Izinzuzo nobubi be-insulin ye-ultrashort
Uma kuqhathaniswa nezinhlobo ze-insulin ezifushane zomuntu, ama-insulin analogue amasha ama-insulin anezinzuzo nobubi. Banokuphakama kwangaphambilini kwesenzo, kodwa-ke isilinganiso segazi labo sehla kakhulu uma utholakele nge-insulin ejwayelekile. Njengoba i-insulin ye-ultrashort inentaba ebukhali, kunzima kakhulu ukuqagela ukuthi udinga malini ama-carbohydrate adingekayo ukuze ushukela wegazi ube ojwayelekile. Isenzo esibushelelezi se-insulin esifushane sifanelwe kangcono kakhulu ukumuncwa kokudla komzimba, uma ulandela ukudla okune-carbohydrate ephansi ukulawula ushukela.
Ngakolunye uhlangothi, umjovo we-insulin emfushane kufanele wenziwe imizuzu engama-40-45 ngaphambi kokudla. Uma uqala ukuthatha ukudla ngokushesha, khona-ke i-insulin emfushane ngeke ibe nesikhathi sokuthatha isinyathelo, noshukela wegazi uzogxuma. Izinhlobo ezintsha ze-insulin ze-insulin ziqala ukusebenza ngokushesha okukhulu, kungakapheli imizuzu eyi-10-15 ngemuva komjovo. Lokhu kulula kakhulu uma ungazi kahle ukuthi sizodingeka nini ukuqala ukudla. Isibonelo, uma usendaweni yokudlela. Uma ulandela ukudla okwe-carbohydrate ephansi, sincoma ukuthi usebenzise i-insulin efushane yomuntu ngaphambi kokudla ezimeni ezijwayelekile. Futhi gcina i-insulin efushane kakhulu ilungele izikhathi ezikhethekile.
Ukuzijwayeza kukhombisa ukuthi izinhlobo ze-insulin ezithinta ushukela wegazi azinze kangako kunalezi zimfushane. Benza kancane ngokubikezela, noma ngabe bajova imithamo emincane, njengoba kwenza iziguli ezinesifo sikashukela, kulandela ukudla okune-carbohydrate engaphezulu, futhi nangaphezulu uma bejova imithamo emikhulu ejwayelekile. Futhi qaphela ukuthi izinhlobo ze-ultrashort ze-insulin zinamandla amakhulu kunezifushane. Iyunithi eli-1 leHumaloga lizokwehlisa ushukela wegazi cishe izikhathi ezi-2,5 kunamandla kune-1 unit ye-insulin emfushane. INovoRapid ne-Apidra zinamandla acishe abe ngu-1.5 kunamandla kune-insulin emfushane. Ngokuvumelana nalokho, umthamo weHumalog kufanele ube cishe ngamaphesenti ama-0,4 we-insulin amafushane, kanye nomthamo weNovoRapid noma i-Apidra - cishe ngomthamo ⅔. Lolu ulwazi olukhombisa ukuthi udinga ukuzicacisela lona ngokuhlolwa.
Umgomo wethu oyinhloko ukunciphisa noma ukuvimba ngokuphelele gxuma ushukela wegazi ngemuva kokudla. Ukufeza lokhu, udinga ukunikeza umjovo ngaphambi kokudla unesikhathi esanele sokuthi i-insulin iqale ukusebenza. Ngakolunye uhlangothi, sifuna ukuthi i-insulin iqale ukwehlisa ushukela wegazi lapho nje ukudla okugayishiwe kuqala ukwandisa. Ngakolunye uhlangothi, uma ujova i-insulin kusenesikhathi kakhulu, ushukela wakho wegazi uzokwehla ngokushesha kunokuba ukudla kungayiphakamisa. Ukuzilolonga kukhombisa ukuthi kungcono ukujova i-insulin emfushane imizuzu engama-40-45 ngaphambi kokuqala kokudla okuphansi kwe-carbohydrate. Okuhlukile kuneziguli ezenze isifo sikashukela sikashukela, is.
Kuyaqabukela, kepha kuze kube yilapho uthola iziguli ezinesifo sikashukela, lapho izinhlobo ezifushane ze-insulin zingeniswa egazini ikakhulukazi kancane. Kufanele bafake i-insulin enjalo, ngokwesibonelo, amahora angu-1.5 ngaphambi kokudla. Vele, lokhu akukhona lula. Badinga ukusebenzisa i-analogue yakamuva ye-ultrashort insulin ngaphambi kokudla, okusheshayo okuyiHumalog. Siphinda sigcizelele ukuthi abantu abanesifo sikashukela bayinto eyenzeka kakhulu.
Ukuqhubeka kwendatshana osanda kufunda kuyikhasi elithi “Ungasibala kanjani isilinganiso se-insulin ngaphambi kokudla. Ungawusehlisa kanjani ushukela abe ejwayelekile ngomjovo we-insulin esheshayo. "
