Indlela ye-hirudotherapy isetshenziselwa ukwenza ngcono i-microcirculation. Indlela engeyona yokuhlinzwa ilawula ukufeza imiphumela emihle ekulweni ne-atherosulinosis, i-inhliziyo yengqondo, kanye nokuphazamiseka kwemithambo yegazi. Le ndlela ivimbela ukuvela kwezinkinga nezindlela ezinzima zokulimala kwangaphakathi futhi ithuthukisa umphumela wokwelapha wezidakamizwa ezilimele.
IHirudotherapy isiza ukubhekana nezinkinga eziningi eziqubuka ezithweni ezibuthakathaka kanye nezinhlelo zazo. Umphumela wama-enzyme walolu hlobo lwezibungu ezincishisiwe usuthole ukusetshenziswa kwendlela yokubuyisa ukungasebenzi kahle emzimbeni we-lipid, ngokukhonjwa kokuqukethwe kwe-cholesterol ephakeme.
Ukweqisa izinga elivumelekile lotshwala obunamafutha emzimbeni kuholela ekuphazamisweni ekusebenzeni kwesistimu ye-vascular, inhliziyo, ubuchopho nezinye izitho nezinhlelo zazo. Okuqukethwe okwandayo kwama-lipids aphansi futhi aphansi kakhulu kucasulula ukwenzeka kwezinguquko ze-atherosulinotic emithanjeni yesistimu yokujikeleza, okuholela ekuphazamisweni kokuhlinzekwa kwegazi ezicutshini futhi, ngenxa yalokho, ukushoda kwezakhi zomzimba nomoya-mpilo kwezicubu.
Izici zokubonisa umthelela yilezi ezilandelayo:
- umsebenzi we-receptor uyathuthuka;
- izakhi zezinto eziphilayo ezisebenza ku-mucus zifaka isandla ekunciphiseni kwegazi, zivimbela ukwakheka kwezigaxa zegazi;
- izinto ezikhiqizwa yilolu hlobo lwama-annelids anciphisa ukuqina kwezinqubo zokuvuvukala;
- ngaphansi kwethonya lezinhlaka ze-mucus, ukusebenza kwendawo kwezindlela zokuvikela ukungasebenzi kwenzeka;
- isibungu esincela ukuphuma kwegazi elisimangaliso sihlanza ukuqongelela ubuthi.
Ezinye izinto ezikhiqizwa isibungu. Futhi kuqukethe umphuzi wayo, unciphise igazi futhi uvimbele ukusebenza kwezinqubo zalo zokuqina. Ama-enzymes aqukethe ku-mucus avimbela umsebenzi we-thrombin futhi asebenze kumuntu njengomuzwa wokubulala izinzwa.
Ngabe yini ukusebenza kwe-hirudotherapy?
Njengamanje, abantu abakhuliswe ngokukhethekile kuma-biofactories asetshenziselwa ukwenza inqubo yokwelashwa. Amagobongo asetshenziswa kaningi njengezindlela zesikhathi esisodwa zokwenza inqubo.
Ukusetshenziswa okukodwa enqubweni yokwelapha kuqeda ngokuphelele ukudluliswa kokutheleleka kusuka kwesinye isiguli kuya kwesinye, okwenza ukwelashwa nge-hirudotherapy kuphephe ngokuphelele kubantu. Ngemuva kwenqubo, umuntu ngamunye angakwazi ukulahlwa.
Ukusetshenziswa kwe-hirudotherapy kunomthelela wokubuyisela emzimbeni womuntu.
Izakhi ezisebenza ngokusebenza kwe-mucus zithinta kahle uhlelo lwe-vascular, zisiza ukuqinisa izindonga zemithambo yegazi. Ngaphezu kwalokho, ukwehla kwe-viscosity kuyabonakala.
Inqubo ilungele abantu abahlupheka ngamazinga aphezulu we-lipoprotein aphansi futhi aphansi kakhulu. Ngenxa yesenzo sezakhi ezisebenza ngokuphila, ukuvela kabusha kwezigcawu ezikhona kwenzeka. Ngaphezu kwalokho, lezi zingxubevange ezisebenzayo zivimba ukwakheka kwama-cholesterol amasha.
Imiphumela eyingozi kakhulu yokuvezwa kwama-lipoprotein aphansi kakhulu futhi aphansi kakhulu ezindongeni zemithambo yegazi yimivimbo kanye nokushaya kwenhliziyo.
Ukuhlanzwa kwegazi kungavimba ukwakheka kwama-cholesterol deposits.
Umphumela oqinisayo wenqubo uyabonakala ngemuva kwesikhashana.
Ama-enzymes aqukethe amathe, ukungena kumuntu, enze isigqi senhliziyo kuvikeleke, kuvikele ukwakheka kwama-cholesterol amasha, akhulise izakhiwo zokuvikela amaseli odonga lwe-vascular.
Ngaphansi kwethonya lezinto ezisebenzayo zemvelo yesibungu, isipani siyakhululeka, ukuphuma kwegazi kuyathuthuka, futhi nomphumela omubi wokuqina kwamangqamuzana uyancipha. Konke lokhu kungenxa yokwehla kwe-viscosity.
Ngasikhathi sinye, ngaphansi kwethonya lezinto ezisebenzayo, i-lipid metabolism emzimbeni iyasebenza, okuholela ekwehlekeni kwenombolo ye-LDL ne-VLDL kanye nokwanda ngasikhathi sinye kwezinga le-HDL. Isilinganiso phakathi kwalezi zingxenye ekwakhekeni kwezinguquko ze-plasma.
IHirudin, ekhishwa yizikelemu, yehlisa ukuqina, okubuye kunciphise amathuba okuqhekeka kwegazi.
Umphumela we-hirudotherapy kubantu
Ngenkathi kwenziwa ucwaningo, kwafakazelwa ngokwesayensi ukuthi i-leeches ene-cholesterol ephakeme yehlisa kakhulu izinga layo, futhi i-hirudin, engena egazini lesiguli, ithuthukisa isimo sohlelo lwezinhliziyo nokusebenza kwenhliziyo. Le ngxenye esebenzayo iqinisa izicubu zezindonga zemithambo yegazi. Isiza ukubuyisa ukwakheka kwabo futhi yenyusa inani le-oxygen. Ukwanda kokuqukethwe komoya-mpilo kusiza ukwenza ngcono ukuhanjiswa kwamaseli wezicubu kuwo, futhi lokhu, kuholela ekunyamalaleni kwezimpawu ze-hypoxia - indlala yamaseli yomoya.
Lapho kwenzeka i-atherosclerosis yamaphethelo aphansi, ukusetshenziswa kwabameleli bezintambo kwenza ukuba sikwazi ukuthuthukisa izicubu zemilenze futhi kuvimbele ukuvela kwezigameko zesibindi.
Ngaphezu kwalokho, inqubo ekwelapheni i-atherosclerosis yamaphethelo aphansi ivimbela ukuthuthukiswa kwezinkinga ngesimo sokufa kwezicubu ne-gangrene.
Ukwelashwa kokuphazamiseka kwephrophic kwezicubu zamaphethelo aphansi, abamele i-annular babekwa ebusweni babo ezindaweni lapho kwenzeka khona ukuzuma, okuthuthukisa ukuhamba kwegazi nokuvuselelwa kwamaseli.
IHirudotherapy ingasetshenziswa njengendlela ezimele yokwelashwa, noma ngokuhambisana nezinye izindlela zokwelashwa kwezifo ze-lipid metabolism.
Lapho isetshenziswa ihlanganiswa nale ndlela, kusetshenziswa ukwelashwa ngokusetshenziswa kwamalungiselelo okwenziwa kwemithi athuthukisa futhi athuthukise ukujikeleza kwegazi, kanye nokuqina kwe-lipid metabolism.
Indlela ikuvumela ukuthi ususe izakhi ezinobuthi ezingathinti kuphela uhlelo lwenhliziyo, kodwa nomzimba wonke.
Ukukhwabanisa okwenziwa ngesikhathi sokwelashwa kunciphisa i-LDL ne-VLDL, kusiza ukumisa izimpawu ezingemnandi ezihambisana nokuqhubeka kwe-atherosclerosis.
Ukusetshenziswa kwe-hirudotherapy kuvimbela ukuthuthukiswa kwe-pathologies efana nemithambo ye-varicose ne-thrombophlebitis, futhi kubuye nokubuyisela umfutho wegazi ngokujwayelekile, ngaleyo ndlela kumiswe izimpawu zokuphazamiseka kwengqondo kanye nomfutho wegazi ophezulu.
Isizathu Esibalulekile Sokuzama Indlela Ehlukile
Ngokuqukethwe okwengeziwe kwe-LDL, i-plaque eyakhiwe egcwalisa i-lumen yemikhumbi iyaphazamisa ukuhamba kwegazi okujwayelekile.
Ukubekwa kwesibungu endaweni yokwakheka kwe-plaque kunomthelela ekuqhekekeni kwayo futhi, ngenxa yalokho, ukubuyiselwa kwe-lumen yomthambo wegazi, othuthukisa ukuhamba kwegazi endaweni yomonakalo.
I-Hirudotherapy ene-cholesterol ephezulu iyindlela enhle yokwenza inqubo yokujikeleza kwegazi ibe yejwayelekile, ngaphezu kwalokhu, indlela isiza ukwenza umsebenzi ube munye kakhulu kwezitho eziningi nezinhlelo zazo.
Inqubo yokwelashwa kwe-atherossteosis inezigaba ezinemibandela ethile:
- Ukukhetha amaphuzu asebenzayo.
- Ukwelashwa okungaphezulu kwesikhumba ngaphambi kokubuyisela abanye abantu kumasayithi asebenzayo.
- Ukudlulisela indandatho emele okomzimba esikhunjeni somuntu endaweni yangaphambi kokulashwa.
Zonke izinqubo zingenziwa ngokwesisekelo sokuphuma, kepha ngaphansi kokuhlolwa ngudokotela. Udokotela. Inqubo kumele iqaphe isimo sesiguli ngesikhathi sokwelashwa ngale ndlela.
Lolu hlobo lokwelashwa lunconyelwa abantu abanokuthambekela kokuxineka neziguli ezinamazinga aphakeme kakhulu we-lipoproteins aphansi futhi aphansi kakhulu.
Izakhi ezisebenzayo zemvelo ezivezwa isibungu zivimba ukwakheka kwezigaba ezintsha zegazi nama-cholesterol plaque, okuvimba ukukhula kokuhlaselwa yisifo senhliziyo nemivimbo, nokuphazamiseka kokusebenza kwengqondo nohlelo lwezinzwa.
Inqubo ivimba ukulimaza kumaseli ngenxa yendlala ye-oksijini, ngenxa yokwephulwa kokujikeleza kwegazi.
I-contraindication eyinhloko ye-hirudotherapy
Le ndlela isiza iziguli eziningi ezihlushwa amazinga aphakeme we-lipoprotein aphansi futhi aphansi kakhulu.
Inzuzo yikhono lokuhlanza igazi kwi-LDL eyeqile kanye nasezakhiweni ezinobuthi, ngaphezu kwalokhu, izakhi zezinto eziphilayo ezisebenzayo zivimbela ukuthuthukiswa kwenqubo yokwenziwa kwe-thrombus.
I-leeches evela ku-cholesterol inegalelo lokwehla kwamandla okuthuthuka kwenqubo yokuvuvukala ezindaweni zomonakalo odongeni lwe-vascular okwenzeka ngenxa yokwakhiwa kwama-plagi atherosselotic.
Ochwepheshe bezokwelapha banquma izifundo zokwelapha, ukuqapha ukuhlaziya nenhlala-kahle yomuntu. Abaphenyi bathi le ndlela isebenzisa isethi yezinqubo zokulungisa amaseli nezakhiwo zawo.
Ukusetshenziswa koshini obumba indandatho kusiza ukwenza ngcono ukuhanjiswa komoya-mpilo kumaseli ngokunxephezela ukushoda kwe-hemoglobin, kanye nokwenza kusebenze i-hematopoiesis.
Ukuhlanzwa komhlaba we-epithelium ngaphakathi kwemithambo yokuqongelela i-cholesterol kwenzeka kancane kancane phakathi nenkathi yokwelashwa. Isiguli sinokuthuthuka kuma-hemodynamics. Ngemuva kwezifundo eziningana zokwelashwa nge-hirudotherapy, i-cholesterol metabolism ijwayelekile.
Lapho usebenzisa le ndlela, kufanele kukhunjulwe ukuthi kunezindlela eziningi eziphikisayo ezinganciphisa ukusetshenziswa kwayo ekwelapheni i-atherossteosis.
Ukuphambana okunjalo yilezi zimo ezilandelayo:
- ukukhathala komzimba;
- ukuba khona kwe-oncological neoplasms esigulini;
- ukuba khona kwe-heestasis pathologies ngesiguli;
- ukutholwa kwezimpawu ze-hypotension kubantu.
Ngaphezu kwalokhu, isikhathi sokuya esikhathini, isimo sokukhulelwa, isimo sokusebenza kokubeletha ezinsukwini zokuqala, i-hemorrhagic diathesis ingahle ibe ukwephulwa kwenqubo. Futhi, phakathi nenqubo, ukungabekezelelani kwesiguli kwizakhi zomsipha kufanele kubhekwe.
Kunenombolo enkulu yokubuyekezwa okuhle, bobabili odokotela neziguli, ngale ndlela yokwelashwa, kepha uma uyisebenzisa, ukubakhona okungenzeka kwe-contraindication kufanele kucatshangwe.
Mayelana ne-hirudotherapy ichazwe kuvidiyo kule ngxenye.
