I-Micrazim (igama elingafuneki emhlabeni jikelele yi-enzyme ebanzi yokukhanya) umkhiqizo ohlanganisiwe wezidakamizwa obandakanya uhla lwama-enzyme asebenza ngokumelene nawo wonke umsoco. Kusetshenziselwa ukuguqula izinqubo zokugaya ukudla kanye nokwenza ngcono umsebenzi wokugaya ukudla.
Ngenxa yokuthi ukwakheka okuyinhloko kwama-enzymes wokugaya kwenzeka kumaseli wamanyikwe, ukuvela kwawo nokuqunjelwa kuyaphazamiseka ngenxa yezinqubo ze-pathological.
Ezimweni ezinjalo, umbuzo umayelana nokuqokwa kwempatho ethile. Kungenxa yalezi zinhloso ukuthi kunqunywe ukwelashwa kwe-enzyme.
Le nto yezidakamizwa iyatholakala ngohlobo lwama-microspheres afakwe kumakhompiyutha e-gelatin. Amakhebuli, wona, ngokuya ngamazinga omhlaba wonke wokugcinwa nokusatshalaliswa kwemithi, afakwe emabhulokini anezinsimbi ezikhethekile. Yikupakisha lokhu okunikela ukuvikela okuphelele kwamakhompiyutha ezintweni ezilimazayo zemvelo. Amabhola afakwa ebhokisini lekhadibhodi. Ibhokisi ngalinye linenombolo ethile yamabhulawu. Ngaphezu kwalokho, iphakethe ngalinye liqukethe imiyalo.
Into esebenzayo yesidakamizwa i-pancreatin ye-classic. Kwethulwa kwifomu le-powder, ukukhishwa kwama-enzyme engulube ye-pancreatic. Umkhiqizo umelelwa ama-enzyme alandelayo:
- i-lipase, i-enzyme ethile ebhekele ukwephulwa kwezakhi ze-lipid;
- i-amylase, i-enzyme ekhuthaza ukugaya okusebenzayo kwama-polysaccharides;
- trypsin, obhekele ukweqiwa kwamaprotheni.
Emakethe yezokwelapha yasekhaya, umuthi uvezwa ngezindlela ezimbili zemithamo:
- Umthamo wezinkulungwane eziyishumi zomsebenzi. Ngokuqukethwe kwama-milligram angama-125 wezinto ezisebenzayo.
- I-Micrasim ngomthamo ka-25,000 uqukethe ama-milligram angama-312 e-pancreatin powder.
Isidakamizwa senziwa ngumkhiqizi wezemithi owaziwayo - "ABBA-RUS". Igama lomuthi lihlotshaniswa nefomu lokukhululwa kwe-micros, futhi into esebenzayo iyi-enzyme.
Ekwenzeni ama-enzyme amaningi asebenzisa izinto ezingavuthiwe zemvelaphi yezilwane - ukukhishwa kwama-enzyme kwezilwane zasemapulazini, okungukuthi izingulube.
Izici ze-Pharmacological zeMikrasim
Ama-enzymes anomthelela ophakeme we-lytic ezingxenyeni zokudla.
Umphumela womuthi kungenxa yokwakheka kwawo. Njengoba ukwakheka kwalesi sidakamizwa kunikeza ukugaya okuphelele kwezakhamzimba.
Izakhi zomuthi zinomphumela obambekayo uma kungaphelelwa ingxenye yengxenye yamanyikwe.
I-enzyme ngayinye ine-pharmacodynamics yayo ethile:
- I-Lipase igqugquzela ukwehlukaniswa kwamafutha ngokusabela kwe-hydrolysis, ngaleyo ndlela iqinisekise ukumuncwa kwawo. Ngaphezu kwalokho, ngenxa ye-lipase esebenzayo, kutholwa amavithamini, isici samakhemikhali okuyi-solubility yamafutha.
- I-Amylase ihlinzeka ukugaya kwama-polysaccharides ngokuwasula kuqala ukuba abe monocomponents.
- Amaprotheni ne-trypsin abhekele ukumuncwa kwamaprotheni.
Ngenxa yomsebenzi omkhulu wokugaya ujusi wesisu, ama-microspheres avikelwe igobolondo le-gelatin. Ngemuva kokuchithwa kwe-capsule, ama-enzyme asebenzayo afinyelela iphuzu lesicelo.
Ukukhishwa kwabo kwenzeka e-duodenum, lapho kwenzeka khona into esebenzayo kakhulu ye-enzymatic.
Lo mkhiqizo wemithi uqeda lezi zimpawu ezilandelayo:
- umuzwa wesisindo epigastrium;
- umuzwa wesisu esigcwele;
- ukwanda kwegesi okwandisiwe nezimpawu ezihambisana nayo;
- umuzwa wokuntuleka komoya ngenxa yokuncipha kwesibabule esichichima amagesi nokudla okungathikamezekile kwesisu namathumbu;
- i-dyspnea ehambisana nezinqubo ezifanayo ze-pathological njengophawu lwangaphambilini;
- isifo sohudo noma okunye ukunyakaza kwamathumbu.
Ngaphezu kwalokho, into esetshenziswayo yezidakamizwa inomthelela ekujwayipheni komsebenzi wamanyikwe.
Imiyalo yokusebenzisa umuthi
Onke ama-enzyme anobubanzi besenzo anomphumela ofanayo we-pharmacokinetic.
Isibonakaliso esiyinhloko somuthi ukuphula izinqubo zokugaya ukudla.
Ukusetshenziswa kwayo kuyehluka kumthamo kanye nemvamisa yokuphatha, kuya nge-nosology. Udokotela we-gastroenterologist noma udokotela ojwayelekile angakunikeza umuthi.
Izinkomba eziphambili zokunquma umuthi yilezi:
- Ukuntuleka kokwehluka kokwehlukahlukana kwamanyikwe e-exocrine. Isimo esinjalo se-pathological sibonwa ku-pancreatitis engapheli noma eyingozi, kanye nasezifo ezinzima zofuzo kanye ne-chromosomal kanye nokukhubazeka. I-Organ ageneis, i-dysplasia, i-cystic fibrosis. Iziguli ezihlushwa i-cystic fibrosis ziphila ngokuswela okungapheli kwe-enzyme, futhi ngenxa yalokho, ukuthatha ama-enzyme kubalulekile kubo.
- Izifo ezingamahlalakhona zesistimu yokugaya ukudla, kufaka phakathi ipheshana lesisu, isibindi ngesibindi.
- Ukulimala kwezitho zesisu, izimo ngemuva kokuhlinzwa okuvulekile, ukwelashwa ngemisebe kanye ne-chemotherapy eningi.
Ukuchazwa okuningiliziwe kwazo zonke izinkomba zokusetshenziswa kwezinto ze-enzymatic kuchazwe kwimiyalo. Iwebhusayithi yomkhiqizi ichaza zonke izinzuzo zomuthi. Ngaphezu kwalokho, kwizithangami ungafunda ukubuyekezwa mayelana nokusebenza kokwelashwa.
Contraindication ukuqokwa kwezinto enzymatic
Njengeminye eminingi yemithi, iMikrasim inezimpawu ezithile zokunciphisa kanye nokulinganiselwa okufanele isetshenziswe.
Yonke imikhawulo ephathelene nokwelashwa nomuthi ikhonjisiwe kokufakwa kwephakeji.
Isigaba sokukhawulelwa, izici zokusebenzisa kanye nemiphumela emibi kufanele sifundwe ngokucophelela ukuze kugwemeke imiphumela emibi.
Umuthi awunakusetshenziswa kulezi zimo ezilandelayo:
- ukuzwela okuphezulu komuntu noma ukungabekezeleli izingxenye zomuthi;
- ukungezwani kwamaprotheni ezilwane;
- i-pancreatitis ye-acute noma necrotic;
- isimila se-pancreatic;
- ukuhlukahluka okungamahlalakhona kwe-pancreatitis;
- izingane ezingaphansi kweminyaka engu-3 ubudala azikwazi ukusebenzisa umuthi ngenxa yobunjalo befomu lomthamo;
- iziguli ze-cystic fibrosis ezingaphansi kweminyaka eyishumi nanhlanu;
- phatha abesifazane abane-microzim ngesikhathi sokukhulelwa nokuncelisa ibele ngokuqapha, uma kungenzeka ukugwema ukunquma umuthi, kungcono ukungawusebenzisi umuthi;
- gwema ukunquma uma isiguli sivame ukuphuza utshwala.
Sebenzisa emaqenjini akhethekile eziguli, njengabesifazane abakhulelwe, kufanele wenziwe kuphela lapho umphumela wezokwelapha okulindelekile uphindaphindwe kaningi kunobungozi obulindelekile kunina noma enganeni.
Yize ukukhulelwa ne-lactation akuyona inkambiso ephelele yokuthatha izinto ze-enzymatic.
Izici zokusetshenziswa kwamalungiselelo we-enzymatic
Imithamo yesiguli esithile ikhethiwe ngokuya ngezinga lokungapheleli komsebenzi we-exocrine organ.
Amaphilisi kufanele aphuzwe ngomlomo ngesikhathi sokudla. Ifomu lomthamo kufanele ligwinywe ngaphandle kokuhlafunwa ligezwe phansi ngengilazi yamanzi.
Udokotela ohambelayo ukhetha umthamo kanye nesikhathi sokwelashwa ngendlela eqondene nomuntu, ngokubheka iminyaka yesiguli, isigaba sesifo, izincomo nokubuyekezwa kochwepheshe bamazwe jikelele. Futhi, umthamo obekiwe ukhethwa ngokuya ngesakhiwo se-biochemical sokudla esidliwayo yiziguli.
Emakethe yezokwelapha kunezidakamizwa eziningi ezinemiphumela efanayo nezakhi. Intengo yesidakamizwa eRussia incike kwinethiwekhi yamakhemisi, izinga lokushintshana kanye nomphakeli. Ngaphezu kwalokho, le ejenti ye-enzymatic ingumkhiqizo wemakethe yezokwelapha yasekhaya, ngaleyo ndlela imelela okushibhile, kodwa okungekho ngaphansi kwe-analogue esebenza kahle yabenzeli abaziwayo abaziwayo:
- Pangrol;
- Ikhoni
- Mezim;
- Ukudla;
- Pancreasim
- I-Hermitage.
Zonke lezi zidakamizwa ziyisikhundla esiphelele somsebenzi we-enzymatic wamanyikwe.
Njengoba intengo yomuthi ihluka eRussia, ungabheka izindleko ezifanele kakhulu. Kepha okokuqala, ukubuyekezwa mayelana nomuthi nezincomo zochwepheshe zinendaba.
Kuyaphumelela ukusebenzisa ama-enzyme ngokuhlangana nezinto ezi-prebiotic (isb. Dufalac), kepha izindleko zawo futhi, okwamanje, ziphezulu.
Imininingwane ngamalungiselelo we-enzyme inikezwe kuvidiyo ekulesi sihloko.
