Umuthi ka-Arthra yi-chondoprotector, imisebenzi yayo ifaka nokukhuthaza izinqubo zokuvuselelwa kwezicubu ze-cartilage.
Umuthi ungoweqembu lezidakamizwa ezihlanganisiwe.
Umuthi uyatholakala ngesimo samaphilisi aphekwe ngefilimu futhi unephunga elithile lesici.
Izibhebhe kukhona okusaqanda, i-biconvex. Umbala wezibhebhe umhlophe noma umhlophe nge-tint ephuzi.
Ukwakheka kwalo muthi kanyekanye kuqukethe izinto ezimbili ezisebenzayo:
- chondroitin sulfate;
- glucosamine hydrochloride.
Umphumela womuthi emzimbeni womuntu uchazwa ngokuningiliziwe emiyalweni yokusetshenziswa kwomuthi.
Isidakamizwa sithengiswa emakhemisi emabhodleleni epulasitiki, afakwe emabhokisini amakhadibhodi. Ibhodlela ngalinye, ngokuya ngokufakwa, lingaqukatha amaphilisi angama-30, 60, 100 noma ayi-120.
Ukwakheka komuthi kanye nomphumela wawo emzimbeni
Ngaphezu kwalokho, ukwakheka komuthi ngaphezu kwalokho kufaka phakathi izakhi ezenza umsebenzi osizayo.
Lezi zingxenye zomuthi yilezi zingxube ezilandelayo:
- I-calcium calcium sulfate ithulisiwe.
- I-Microcrystalline cellulose.
- I-Croscarmellose sodium.
- I-Stearic acid.
- I-Sodium stearate.
Ukwakheka kwegobolondo lethebhulethi ngayinye kufaka phakathi izinto ezilandelayo:
- titanium dioxide;
- unxantin;
- hydroxypropyl methylcellulose.
Enye yezingxenye ezisebenzayo zomuthi chondroitin. Le khompiyutha ingasebenza njengesisekelo esengeziwe ekwakhekeni kwe-cartilage elandelayo, enesakhiwo esijwayelekile.
Ngaphezu kwalokho, le ngxenye inomthelela ekuvuseleleni kwezinqubo zokukhiqiza ze-hyaluron. I-Chondroitin ibuye ifake isandla ekuvikelweni kwe-hyaluron ekucekelweni phansi kwe-enzymatic.
Ukungena kwe-chondroitin emzimbeni womuntu kusiza ukwenza kusebenze ukwakheka kwama-proteinoglycans bese uthayipha i-2 collagen.
Omunye umsebenzi obaluleke kakhulu owabelwe le ngxenye yesidakamizwa ukuvikela izicubu ze-cartilage ezikhona ekuvezweni kwezinto ezingezinhle ezenzeka ngesikhathi kusungulwa ama-radicals mahhala.
Ingxenye yesibili esebenzayo yesidakamizwa - i-glucosamine hydrochloride nayo iyi-chondroprotector, kodwa-ke, umgomo wokusebenza kwaleli khompiyutha uhlukile ku-chondroitin.
I-Glucosamine ivuselela ukuhlanganiswa kwezicubu ze-cartilage futhi ngasikhathi sinye leli khompiyutha livikela izicubu ze-cartilage ezivela emiphumeleni emibi yamakhemikhali.
Le ngxenye yesidakamizwa ivikela i-cartilage izicu emiphumeleni emibi kuyo yezidakamizwa eziseqenjini lama-glucocorticoids nezidakamizwa ezingezona ze-steroidal ezinezinto zokulwa nokuvuvukala. Le mishanguzo ibhubhisa i-cartilage, kepha esimeni sokwelapha izifo ezithinta amalunga, kuyaqabukela ukwenze ngaphandle kwemithi engokwalawa maqembu emithi.
Ukusetshenziswa kwalamathuluzi kukuvumela ukuthi uthathe ukulawula kobuhlungu obukhulu endaweni yezikhwama ezibanzi.
I-Pharmacokinetics yesidakamizwa
Ukwethulwa kwesidakamizwa kukuvumela ukuthi ulondoloze ukubonwa okungamanzi we-synovial ezingeni lomzimba.
Ngaphansi kwesenzo se-Arthra yezidakamizwa, isenzo sama-enzyme anjenge-elastase ne-hyaluronidase siyacindezelwa, okunomthelela ekuwohlokeni kwezicubu ze-cartilage.
Ekwelashweni kwe-osteoarthritis, ukusetshenziswa kwe-Arthra kungadambisa izimpawu zesifo futhi kunciphise kakhulu isidingo semithi engeyona eye-steroidal elwa nokuvuvukala.
I-bioavailability yengxenye enjalo yesidakamizwa njenge-glucosamine lapho ithathwe ngomlomo ingama-25%. I-bioavailability ephezulu ye-glucosamine kungenxa yemiphumela yendima yokuqala edlula esibindini.
I-bioavailability ye-chondroitin sulfate icishe ibe yi-13%.
Izakhi zomuthi zisatshalaliswa ngaphezulu kwezicubu zomzimba.
Ukuhlushwa okuphezulu kakhulu kwe-glucosamine kutholakala izicubu zesibindi, izinso kanye nenhliziyo.
Cishe i-30% yomthamo osetshenzisiwe wesidakamizwa uphikelela isikhathi eside kwezicubu zamathambo nezemisipha.
Ukususwa kwe-glucosamine kwenziwa ngokungashintshiwe ngokusebenzisa izinso emchameni. Ngokwengxenye, lesi sakhi esisebenzayo sikhululiwe ezindlebeni.
Ukuphila kwesigamu umuthi okuvela emzimbeni kungamahora angama-68.
Imiyalo yokusebenzisa umuthi
I-Arthra yezidakamizwa isetshenziswa ekwelapheni izifo ezinhlobonhlobo zokuwohloka kwe-dystrophic, okunomthelela ekuqubukeni kokuphazamiseka ohlelweni lwe-musculoskeletal.
Imvamisa, izidakamizwa zisetshenziselwa ukwelapha izifo ezinjenge-osteoarthritis yamalunga nezihlanganisi ezakha umgogodla.
Isidakamizwa sinconywa ukuthi sisetshenziswe ezigabeni zokuqala zokukhula kwezifo ezithinta izicubu zenhliziyo. Lesi sincomo, esiqukethwe yiziyalezo zokusebenzisa umuthi, siqinisekiswa yimpendulo yodokotela abasebenzayo. Ezigabeni zakamuva zokuqhubeka kwezifo, ukusetshenziswa kwama-chondroprotectors akunampumelelo.
Ukuphikisana ngokuphelele nokusetshenziswa kwomuthi ukubakhona kwesiguli sokwephulwa kokusebenza kwezinso kanye nokuba khona kwesiguli esinokuzwela okuphezulu kuzakhi ezakha umuthi.
Ukuphazamiseka kwezinso nezinso kuvame ukuhambisana nokuqhubeka kwesifo sikashukela.
Ngalesi sizathu, ngesifo sikashukela, umuthi kufanele usetshenziswe ngokucophelela okukhulu.
Ngaphezu kwalokho, akunconywa ukusebenzisa umuthi uma isiguli sine-asthma ye-bronchial ne-mellitus yesifo sikashukela kanye nokuthambekela okuphezulu kokopha.
Kuyinto engathandeki ukusebenzisa umuthi ngesikhathi sokubeletha kanye nokuncelisa ingane.
Imvamisa, lapho kungekho khona ukungqubuzana, ukusetshenziswa komuthi i-Arthra ngenkathi kwelashwa izifo ezihlangene kubekezelelwa kahle yisiguli, kepha kunezimo lapho ukusetshenziswa komuthi kuvusa khona ukuvela kwemiphumela emibi emzimbeni.
Imiphumela emibi ejwayelekile ingahlanganisa okulandelayo:
- Ukuphazamiseka kwasemgunjini wokugaya ukudla, okukhonjiswa yisifo sohudo, ukubhebhetheka, ukuqunjelwa nobuhlungu esifundeni se-epigastric.
- Ukuphazamiseka ohlelweni oluphambili lwezinzwa - isiyezi, ikhanda elibuhlungu nokuphendula komzimba.
Lapho kukhona isifo sikashukela esigulini, ukusetshenziswa komuthi kufanele kwenziwe kuphela ngemuva kokubonisana nodokotela wobugqila.
Umthamo wezidakamizwa, izifanekiseli zawo kanye namanani
Umuthi usetshenziswa ekwelapheni izifo ezihlangene isikhathi eside. Imvamisa, isikhathi sezifundo zokwelapha okungenani izinyanga eziyi-6. Ukusetshenziswa okunjalo isikhathi eside kuphela lapho umuthi ovela eqenjini lama chondroprotectors unganikeza umphumela omuhle ozozinza impela.
Isidakamizwa sinconywa ukusebenzisa iphilisi elilodwa kabili ngosuku amasonto amathathu. Ekupheleni kwalesi sikhathi, kufanele ushintshe ukuthatha ithebhulethi elilodwa ngosuku.
Umuthi uthengiswa emakhemisi ngaphandle kwemiyalelo kadokotela. Kodwa-ke, kufanele kukhunjulwe kuzo zonke iziguli ezinenkinga yesifo sikashukela ukuthi isifo sikashukela singavusa ukuthuthukiswa kokuphazamiseka emsebenzini wezinso, ngakho-ke ngaphambi kokusebenzisa umuthi, kufanele uvakashele udokotela wakho futhi ubonisane ngokusetshenziswa kwe-Arthra.
I-analogue esiseduzane ye-Arthra isidakamizwa Teraflex. Lo muthi ukhiqizwa ngezinhlobo ezimbili zemithi - Teraflex ne-Teraflex Advance. I-Teraflex ne-Teraflex Advance yohlobo lwesifo sikashukela sohlobo 2 zingasetshenziswa ngisho nangezinjongo zokuvimbela.
Kufanele kuqashelwe ukuthi iTeraflex akuyona i-analogue ephelele ye-Arthra.
Izindleko zomuthi i-Arthra eRussia zixhomeke esifundeni lapho lo muthi wawuthengiswa khona nenkampani ewuthengisayo. Ngaphezu kwalokho, izindleko zomuthi zincike ekutheni ukuthengwa komkhiqizo kuthengiwe.
Iphakheji enamathebhulethi angama-30 inezindleko ezingama-ruble angama-600 kuye kwangama-700, iphakheji enamathebhulethi angama-60 inezindleko ezingama-ruble angama-900 kuye kwangama-1200.
Amaphakethe amakhulu aqukethe amaphilisi ayi-100 no-120 anezindleko ezingama-ruble ayi-1300 kuya kwangama-1800. Inkambo yokwelashwa kwalesi sifo idinga ukusetshenziswa kwamathebulethi ayi-200.
Imininingwane ngemiphumela yama-chondoprotectors kumajoyinti inikezwe kuvidiyo ekulesi sihloko.
