Isifo sikashukela i-mellitus sesibe yinkinga enkulu emphakathini wanamuhla. Ukwelashwa ngezidakamizwa kumane nje kudingekile ukugwema imiphumela emibi. Umuthi owodwa ojwayelekile futhi osebenzayo yi-Diabeteson, uthathwa isifo sikashukela sohlobo 2. Kumele kwaziwe ukuthi odokotela abaningi bayawemukela lo muthi, futhi iziguli zivame ukusabela kahle kulo muthi.
Isithako esikhulu esisebenzayo somuthi yi-glycazide yamakhemikhali. Le khompiyutha ikhulisa umsebenzi wamaseli we-pancreatic beta. Ukugqugquzelwa kwamaseli kuholela ekukhiqizweni okwandayo kwe-insulin ye-hormone. I-Glycaside ingukuphuma kwe-sulfonylurea.
I-Diabeteson isetshenziswa ekwelapheni uhlobo lwesifo sikashukela sohlobo 2 ngemuva kokuthathwa kwenkambo yokwelapha ye-metformin. I-Diabeteson akuyona ithuluzi lezokwelapha lokuqala ukukhetha ekwelashweni kwesifo sikashukela sohlobo 2.
Izici ezijwayelekile zomuthi
I-Diabeteson yezidakamizwa ifakiwe eqenjini lezidakamizwa ze-sulfonylurea futhi ibhekwa njengenye yezindlela ezinhle kakhulu, ngoba ayinazo izingqinamba eziningi futhi ayinayo imiphumela emibi kakhulu. Izwe lokukhiqizwa kwalo muthi yiFrance, Russia neJalimane.
Umuthi ungowesigaba se-pharmacological sabenzeli be-hypoglycemic yomlomo, okuphuma ku-sulfonylureas kwesizukulwane sesibili.
Amathebulethi atholakala emabhulashini. Iphakethe ngalinye lesidakamizwa liqukethe amanxeba amabili amaphilisi ayi-15 nemiyalo yokusebenzisa umuthi. Ukufakwa kwenziwa ngekhadibhodi
Umuthi ukhishwa ngendlela yamathebulethi. Isakhi esiyinhloko salo muthi yi-gliclazide, esivusa ukukhiqizwa kwe-insulin ngamangqamuzana e-beta pancreas. I-Diabeteson MV umuthi wokukhishwa oguquliwe lapho i-gliclazide ingadedelwa khona ngokushesha, kepha kancane kancane isikhathi esingamahora angama-24. Le mpahla yesidakamizwa inikeza izinzuzo ezithile lapho wenza ukwelashwa kwezidakamizwa sikashukela.
Ithebhulethi libekelwe uhlobo 2 lwesifo sikashukela ezigulini zabantu abadala, lapho ushukela wegazi ungalawulwa ngokudla, ukuvivinya umzimba noma ukunciphisa umzimba. Ukusetshenziswa kwaso kungenzeka ngezinjongo zokuvimbela ukuze kugwemeke izinkinga zesifo:
- I-Nephropathy - umsebenzi wezinso ophazamisekile, ikakhulukazi, iziqithi zeLangerhans.
- Ama-retinopathies ayizilonda ezi-retina.
- Ukufakelwa kwe-Myocardial kanye nesifo sohlangothi kunemiphumela emincane kakhulu.
Lapho uthatha isifo sikashukela, imiphumela emihle kakhulu iyabonakala:
- ukuvikeleka okuthuthukile kwe-insulin ye-hormone;
- amathuba okuncipha kwe-vascular thrombosis;
- izakhi zomuthi zinezakhi ze-antioxidant.
Kodwa-ke, akathathwanga njengesisekelo sokwelashwa. Lawa maphilisi kashukela athathwa kuphela ngemuva kwenkambo ye-metformin.
Imiyalo yokusebenzisa umuthi
Ukuthatha i-Diabeteson, okokuqala udinga ukubonana nodokotela wakho. Nguye kuphela onga khetha umthamo ofanele ngokususelwa eminyakeni isiguli kanye nezimpawu zayo. Ithebhulethi elilodwa liqukethe ama-60 mg we-gliclazide. Kuyelulekwa ukusebenzisa umkhiqizo ekuseni ngokudla, ukugwinya ngokushesha ngaphandle kokuhlafuna. Imithamo emaphakathi yesidakamizwa yilena:
- Isifo sikashukela esingaphansi kweminyaka engama-65: umthamo wokuqala ungamaphilisi angama-0.5. Ngokukhula komthamo, thatha enye ithebhulethi engu-1. Ukuze ulondoloze ukwelashwa, kunconywa ukusetshenziswa kwamathebhulethi ama-1-2 ngosuku.
- Iziguli ezingaphezu kweminyaka engama-65 ubudala: zabaqalayo, thatha amaphilisi ayi-0.5 ngosuku. Ukungezelela umthamo kukuvumela ukuthi uthathe elinye ithebhulethi eli-1, kodwa ngokuhamba kwamasonto amabili. Kulokhu, iziguli kumele zihlale zihlola ushukela wazo.
- Iziguli ezinokulimala kwe-renal noma hepatic, okungenamsoco noma ngezikhathi ezithile kufanele zigcine ngokuqinile yonke imithamo bese ziqala ngenani elincane kakhulu (1 ithebhulethi ngosuku).
Ezimweni lapho isiguli sisebenzise esinye isidakamizwa sikashukela, ukuguqulela ku-Diabeteson kuvunyelwe. Ukuhambisana kwalo muthi kuphezulu kakhulu namanye ama-ejenti. Kepha ngemuva kokusebenzisa i-chlorpropamide, lezi zibhebhe kufanele zithathwe ngokuqapha ngokweqile ngaphansi kokuqondisa kukadokotela ukugwema ukuthuthukiswa kwe-hypoglycemia.
I-Diabeteson MB ingahlanganiswa ne-insulin, i-alpha glucosidase inhibitors nama-biguanidin.
Contraindication kanye nemiphumela emibi
Ngaphambi kokusebenzisa umuthi, udinga ukwazi mayelana ne-contraindication yayo:
- Ukungabekezelelani komuntu ngamunye engxenyeni eyinhloko - i-gliclazide noma ezinye izinto.
- Thayipha isifo sikashukela sokuqala esingu-1 (ifomu lokuncika kwe-insulin).
- Idlozi likashukela, iketoacidotic noma i-hyperosmolar coma.
- Ukwehluleka kwe-Hepatic ne-reso.
- Isikhathi sokukhulelwa nokuncelisa ibele.
- Ukungabekezeleleki kwento - i-lactose.
- Izingane ezingaphansi kweminyaka engu-18.
- Akuvunyelwe ukuhlanganisa umuthi ne-phenylbutazone ne-danazole.
Ngaphandle kokuthi ukubuyekezwa mayelana nalesi sidakamizwa kuhle kakhulu, isiguli esiphuza amaphilisi singasathola imiphumela emibi elandelayo:
Ukuthuthukiswa kwe-hypoglycemia. Ukwehla okukhulu ushukela wegazi, isiguli kungadingeka sishintshe inkambo yokwelashwa. Ukuphazamiseka kwendlela yokugaya ukudla: isifo sohudo, isicanucanu, ukuhlanza, nobuhlungu besisu. Ngakho-ke, kubalulekile ukwazi ukuthi ungaphuza kanjani iphilisi ngokufanele.
Ukungezwani komzimba ngendlela yokuqhuma kwesikhumba, ubomvu, ukulunywa. Ezimweni ezingavamile, i-anemia ngenxa yezinguquko ekusebenzeni kwezinhlelo ze-lymphatic ne-endocrine. Imiphumela emibi engavamile kakhulu - i-hepatitis, ukungasebenzi kahle kwesibindi kanye nombono.
Ngaphambi kokuthatha umuthi, isiguli kumele ngaso sonke isikhathi sibonane nodokotela ezimweni ezinjalo:
- nefomu elingelapheki lokudakwa (iDiabeteson nobhiya, i-vodka, njll ayihlanganisiwe);
- ngokudla okungajwayelekile;
- ukwephula ukwenziwa kwama-hormone yi-pituitary gland kanye nezindlala ze-adrenal;
Ukubonisana kuyaphoqeleka futhi uma kukhona okungahambi kahle ekusebenzeni kwendlala yegilo emzimbeni.
Amanani nokubuyekezwa kwesiguli
Umuthi ungathengwa kunoma iyiphi ikhemisi noma uyalwe online. Intengo emaphakathi yomuthi ingama-ruble angama-350. Yize amakhemikhali akwe-inthanethi evame ukubiza kancane - cishe ngama-ruble angama-280.
Ngenxa yesenzo esithambile salo muthi, ukubuyekezwa ngakho muhle kakhulu. Iziguli ezithola ukwelashwa ngamathebhulethi ziveze izinzuzo ezilandelayo:
- umuthi wehlisela ushukela wegazi ngempumelelo;
- umthamo owodwa wamathebulethi kulula kakhulu;
- isisindo somzimba empeleni asikhuphuki.
Ngaphezu kwalokho, ucwaningo luye lwabonisa ukuthi amathuba we-hypoglycemia awekho ngaphezu kwe-7%, aphansi kakhulu kunezinye izidakamizwa. Ngakho-ke, leli qiniso lingabhekwa njenge-plus enkulu.
Kepha kwezinye izikhathi, abantu bakhulume kabi ngoDiabeteson. Ngakho-ke, ubunzima bomuthi bungabhekwa:
- uhlobo lwesibili lwesifo sikashukela lungaya kolokuqala kungakapheli iminyaka eyi-8;
- kubantu abanciphile ngokweqile ukukhathala, ukusetshenziswa kwalesi sidakamizwa kudala inguquko kumijovo ye-insulin ngokuhamba kwesikhathi.
Iziguli eziningi ziyazibuza ukuthi kuyiqiniso noma ngamanga ukuthi isifo sikashukela siholela ekwehleni kokuzwela kwe-insulin. Ucwaningo lwakamuva luye lwabonisa ukuthi isidakamizwa sandisa ukumelana ne-insulin, okungukuthi, ukuncipha kokuzwela kwamangqamuzana nezicubu ku-insulin.
Izibalo zikhombisa ukuthi ngokwehla kwe-glucose egazini, ukufa kwabantu kuhlala kusezingeni elifanayo.
Okukhona okufana nezidakamizwa
Kwezinye izimo, ngokwesibonelo, lapho isiguli sithola ukungabekezeleleki kwezakhi, kuyadingeka ukubuyisela okunye ukwelashwa ngemithi e-analogous. I-Diabeteson MV ingathathelwa indawo yizindlela ezilandelayo:
- I-Metformin. Njengoba kushiwo ngaphambili, nalesi sidakamizwa udinga ukuqala ukwelashwa. Lapho uthatha umuthi, umehluko omkhulu, ngoba akubangeli i-hyperglycemia, ngokungafani nezinye izidakamizwa.
- Maninil. Naphezu kokusebenza kahle kwalo muthi, ubangela ukulimala okukhulu emzimbeni, okwenza inani elikhulu lokubi okungahambi kahle.
- Siofor. Isithako esikhulu esisebenzayo yi-metformin. Esigulini sithatha lesi sidakamizwa, ukuzwela kwezicubu kokunyuka kwe-insulin, amazinga kashukela kuyancipha, isifiso sokudla siyacindezelwa, nesisindo somzimba siyancipha. I-Diabeteson neSiofor yomibili imishanguzo emihle, futhi ngudokotela kuphela ongakunikeza umuthi ofanele, onesisindo sokuhle nokubi.
- I-Glucophage. Leli thuluzi futhi liqukethe isithako esisebenzayo - i-metformin. Lapho usebenzisa umuthi, iziguli ziphawula ukuzinza kwamazinga kashukela, ukuncipha kwesisindo, kanye nokungabikho kwezinkinga zesifo sikashukela.
- Ama-Glucovans. Ukwakheka kuqukethe izinto ezimbili eziyinhloko - glibenclamide ne-metformin. Lezi zingxenye zandisa ukuzwela kwezitho nezicubu ze-insulin.
- Amaril. Kuqukethe isithako esisebenzayo - glimepiride. Ukwanda kokuqunjelwa kwe-insulin, ngasikhathi sinye, umuthi ubangela imiphumela emibi eminingi efana nokugayeka, ukubona okungalungile kanye nokwehla ngokushesha koshukela wegazi.
- I-Glibomet. Umuthi usekelwe ku-metformin ne-glibenclamide. Ithuluzi livusa ukukhululeka kwe-insulin. IGlybomet iyenqatshelwa ukuthatha nesifo sikashukela sohlobo 1. I-Glibomet ithathwa amaphilisi angu-1-3. Umthamo omkhulu ovunyelwe uGlybomet unamathebhulethi ayi-6. Umuthi i-Glybomet uthathwa kuphela ngokuya ngencwadi, umuthi wokuzelapha uvunyelwe.
Enye indlela engcono kakhulu kuyo yonke imithi ukuqoqwa ngamakhambi. Vele, kunoma yikuphi, akunakwenzeka ukukhansela ngokuphelele ukwelashwa kwezidakamizwa. Leli qoqo lizosiza ukunciphisa i-glucose futhi lenyuse ukungazinzi kwabantu. Imali ingathengwa kunoma iyiphi ikhemisi. Imvamisa iqukethe utshani bama-blueberries, i-sage, imbuzi, izithelo ze-fennel, amaqabunga ama-blackberry, izimpande ze-licorice, i-dandelion ne-burdock, amaqabunga obhontshisi.
I-licorice, i-burdock, ama-blueberries, ikakhulukazi iqabunga le-blueberry, ibuyisela amaseli we-pancreatic beta. Azikho ngeze ezibizwa ngokuthi ama-stimulants. Izitshalo ezisele zingama-sweeteners wemvelo. Ukuqoqwa kwamakhambi kumele kudakwe kathathu ngosuku.
Lapho ukhetha ama-analogues, isiguli kufanele ngaso sonke isikhathi sibonane nodokotela wakho. Izidakamizwa zinezindleko ezihlukile, ngakho-ke lesi isici esibalulekile ekukhetheni umuthi ofanele.
Ngokulashwa okufanele kwesifo sikashukela, isiguli kufanele siyeke imikhuba emibi, siphile impilo enempilo kanye nokudla okunempilo. Ukwelashwa ngezidakamizwa kungenye yezinto eziphambili ekulweni nalesi sifo. Ngakho-ke, udokotela nesiguli kufanele bangathí sina ngokukhetha umuthi ofanele. I-Diabeteson MV yindlela enhle ekwelapheni lesi sifo. Kodwa-ke, kufanele kukhunjulwe ukuthi indlela engalungile yokusebenzisa umuthi ingadala izinkinga. Uma kunesidingo, udokotela uzokwazi ukuthatha ama-analogues noma anikeze iqoqo lezikhambi. Ividiyo ekulesi sihloko izoqhubeka nesihloko somuthi.
