Isifo sikashukela yi-pathology ejwayelekile kakhulu ye-endocrinological. Lesi sifo sinezinhlobo ezimbili - sincike kwe-insulin futhi sincike ku-insulin. Isifo sikashukela i-mellitus yisifo esingamahlalakhona.
Ekwelapheni lesi sifo, kusetshenziswa izidakamizwa ezisiza ngokwejwayelekile amazinga eglucose. Enye yezidakamizwa ezidumile zalolu hlobo yi-Glucobai 100 mg. Umuthi usetshenziswa zombili ekwelapheni isifo sikashukela sohlobo 1 nasekwelapheni isifo sikashukela sohlobo 2 futhi udokotela usibekela lesi sifo.
Umuthi ukhiqizwa ngendlela yamathebulethi. I-Glucobai 50 mg ne-100 mg iyathengiswa. Ziyahluka phakathi kwenani lezinto ezisebenzayo kuthebhulethi eyodwa. Intengo yesidakamizwa ama-ruble angama-660-800. Lapho uthenga umuthi, kufanele wethule umuthi ofanele ofanele ovela kudokotela wakho.
Isenzo se-Pharmacological se-Glucobay
IGlucobai yi-ejenti ye-hypoglycemic yokusetshenziswa komlomo. Isakhi esisebenzayo somuthi yi-acarbose. Lokhu kuqinisa izinga le-glucose egazini.
Ngabe umuthi usebenza kanjani? I-Acarbose yinto evimbela i-alpha glucosidase yamathumbu. Isakhi esisebenzayo somuthi futhi sinciphisa ukuguqulwa kwe-enzymatic kwama-disaccharides, ama-oligosaccharides nama-polysaccharides kuma-monosaccharides. Ngenxa yalokhu, izinga lokufakwa kweglucose esiswini liyancishiswa.
Kuyaphawuleka ukuthi ngokusetshenziswa kwamathebulethi, i-hypoglycemia ebukhali ayiqhubeki. Ukudla njalo umuthi kunciphisa ubungozi bokuthuthuka:
- I-Myocardial infarction.
- Ukuhlaselwa kwe-hypoglycemia ne-hyperglycemia.
- Ukuthuthukiswa kwezifo ezingamahlalakhona kohlelo lwezinhliziyo.
Ukuqoqwa okuphezulu kwento esebenzayo egazini kuyabonakala ngemuva kwamahora ama-1-2. Ama-metabolites angasebenzi womuthi athiwa ngamathumbu, izinso nesibindi.
Imiyalo yokusebenzisa umuthi
Lapho uqoka i-Glucobai, imiyalo yokusebenzisa kufanele ifundwe, ngoba iqukethe lonke ulwazi nezinkomba, ukuphikisana nemiphumela emibi. Kukuwe ngasiphi isimo lapho kufanelekile ukuthatha lo muthi?
Imiyalo ithi umuthi kufanele usetshenziswe ekwelapheni okunesifo sikashukela sohlobo 1. Futhi inkomba yokusetshenziswa isifo sikashukela sohlobo 2. Ungawusebenzisa umuthi ukukhuluphala nesifo sikashukela.
Kodwa ukunciphisa umzimba ngosizo lweGlucobay kungenzeka kuphela uma ulandela ukudla okhethekile. Kubalulekile ukuqaphela ukuthi umuntu ophelelwa isisindo kufanele adle okungenani ama-kilocalories ayi-1000 ngosuku. Ngaphandle kwalokho, i-hypoglycemia ebukhali ingahle ibe khona, kuze kufike ekuhlaselweni kwe-hypoglycemic.
Ungawuthatha kanjani umuthi? Phuza amaphilisi ngaphambi kokudla. Umthamo wokuqala ngu-150 mg. Hlukanisa umthamo wansuku zonke uthathe imithamo emi-3. Uma kunesidingo, umthamo uphakanyiselwa ku-600 mg. Kodwa kulokhu, umthamo wansuku zonke kufanele uhlukaniswe ngemithamo ye-3-4.
Uma ngesikhathi sokwelashwa isiguli sinokuhlatshana kanye nohudo, khona-ke umthamo kufanele wehliswe, noma ukwelashwa kufanele kuphazanyiswe ngokuphelele. Isikhathi sokwelashwa nge-Glucobaem sikhethwe ngokwahlukile.
Ukuxhumana kokuthathwa kwamathebulethi:
- Ukungezwani komzimba kwizakhi zomuthi.
- Iminyaka yezingane. Umuthi awubekelwe iziguli ezingaphansi kweminyaka engu-18.
- Ukuba khona kwesifo samathumbu esibuhlungu noma esingamahlalakhona. Ukubuyekezwa kodokotela kukhombisa ukuthi umuthi uyingozi ukunquma abantu abahlushwa amathumbu.
- Isifo sikashukela sikashukela.
- Ukuphazamiseka kwesibindi. Kwenqatshelwe ngokuphelele ukusebenzisa umuthi uma umuntu enenkinga yokuhluleka kwesibindi, i-cirrhosis noma i-hepatitis.
- Izilonda ezisesiswini zamathumbu noma ezinye izitho zomgudu wesisu.
- Isikhathi sokukhulelwa.
- Isikhathi sokuzala. Kepha imiyalo ithi umuthi ungabekelwa ukuba u-lactating abesifazane ngaphansi kokumiswa okwesikhashana kokuncelisa ibele.
- Ukwehluleka kwangempela (ngokuqukethwe kwe-creatinine ngaphezulu kwe-2 ml nge-1 dl).
- Isifo sikaRemgeld.
- Ukuba khona kwe-hernias enkulu odongeni lwesisu.
- I-Malabsorption syndrome noma i-maldigestion.
Ngokuqapha, umuthi ubekelwe abantu ngemuva kokuhlinzwa. Futhi, ukulungiswa kwerejimeni yokwelashwa kungahle kudingeke uma umuntu enezifo ezithathelwanayo noma umkhuhlane. Kuyaqapheleka ukuthi ngesikhathi sokwelashwa, ukudla okugcwele i-sucrose ngeke kudliwe. Ngaphandle kwalokho, kungaba nezimpawu ze-dyspeptic.
Ngabe iGlucobai ihlangana kanjani neminye imithi? Kusungulwe ukuthi umuthi awusebenzi kahle uma kuthathwa amathumbu, ama-antacid noma ama-enzyme amalungiselelo nawo. Kufanele futhi kukhunjulwe ukuthi ngokusetshenziswa kanyekanye kweGlucobay nge-sulfonylurea derivatives noma i-insulin, umphumela we-hypoglycemic uyathuthukiswa.
Kunconywa kakhulu ukuthi ungasebenzisi leli thuluzi kanye ne-thiazide diuretics, inzalo yokuvimbela inzalo ngomlomo, i-corticosteroids, i-nicotinic acid. Ngokusebenzisana kwabo, ukubola kweshukela kungakhula. Futhi, le ndlela yokusebenza kwengqondo ingakhula uma uthatha ama-phenothiazines, ama-estrogens, ama-isoniazid, ama-calcium blockers, ama-adrenomimetics ngasikhathi sinye neGlucobai.
Uma usebenzisa amaphilisi we-Glucobai, kungenzeka ukuthi kuvela kwemiphumela emibi efana nalena:
- Ukusuka emgudwini wokugaya ukudla: izinhlungu ze-epigastric, isicanucanu, uhudo, ukuthopha. Uma kwenzeka kweqisa ngokweqile, kunethuba lokukhuphuka kwe-asymptomatic ezingeni lomsebenzi wama-enzyme wesibindi. Amacala ayaziwa futhi lapho ukukhula kwamathumbu, i-jaundice ne-hepatitis kukhula ngesikhathi sokwelashwa.
- Ukungezwani komzimba.
- Ukuvuvukala.
Uma kwenzeka kune-overdose, ukusabela kwe-anaphylactic kungaqala ukuvela. Kulokhu, ukwelashwa okubonakalayo kwenziwa.
I-analogue enhle kakhulu yeGlucobay
Uma i-Glucobay iphikisiwe nganoma yisiphi isizathu, isiguli sinikezwa izifanekiselo zeqembu laso. Ngokungangabazeki, enye indlela engcono kuleli thuluzi yi-Glucofage. Lesi sidakamizwa sisetshenziswa nasekwelapheni isifo sikashukela sohlobo 1 nohlobo 2. Izindleko zomuthi emakhemisi ngama-ruble angama-500-700.
Abantu abaningi banesifiso sokuthi yini umehluko phakathi kweGlucofage neGlucobay. Umehluko omkhulu phakathi kwalezi zidakamizwa ukwakheka kanye nenqubo yokusebenza. Kepha zombili lezi zidakamizwa zisebenza ngokulinganayo.
Ngabe isebenza kanjani i-glucophage? Ingxenye esebenzayo yesidakamizwa ibizwa nge- metformin. Le nto inomphumela obizwa ngokuthi yi-hypoglycemic. Kuyaphawuleka ukuthi ezigulini ezinamazinga kashukela wegazi ajwayelekile, i-metformin ayinawo umphumela we-hypoglycemic.
Indlela yokusebenza ye-Glucofage isuselwa emandleni engxenye yayo esebenzayo yokwandisa ukuzwela kwamangqamuzana ukufaka i-insulin futhi kunciphise izinga lokufakwa kweglucose emgodini wokugaya ukudla. Ngakho-ke, lo muthi unesiza kulokhu:
- Yehlise ukwakheka koshukela esibindini.
- Ukugqugquzela ukusetshenziswa kwe-glucose ezicutshini zemisipha.
- Thuthukisa i-lipid metabolism.
- I-cholesterol ephansi, ama-triglycerides nama-lipoprotein, anokuqina okuphansi.
I-Glucophage ingahlukaniswa ukusebenza kwayo kwezinye izidakamizwa ze-hypoglycemic. Lokhu kungenxa yokuthi umuthi unezinkomba eziphakeme ze-bioavailability. Benza cishe i-50-60%. Iqoqo eliphezulu lezinto ezisebenzayo zomuthi osegazini ziqashelwa ngemuva kwamahora ayi-2,5.
Ungawuthatha kanjani umuthi? Udinga ukuphuza amaphilisi ngesikhathi sokudla noma ngaphambi kokudla. Umthamo wansuku zonke uvame ukuba ngamagremu ama-2-3 (ama-2000 ukuya ku-300 wamamilimitha). Uma kunesidingo, ngemuva kwezinsuku eziyi-10-15, umthamo uyandiswa noma wehlisiwe. Umthamo wokulondolozwa ngu-1-2 amagremu. Kuyaqapheleka ukuthi umthamo wansuku zonke ungahluka. Ngezindlela eziningi, kunqunywa umthamo we-insulin.
Umuthi uvinjelwe:
- Umzimba ezingxenyeni ze-glucophage.
- Ukwehluleka kwangempela
- Ukwephulwa kwesibindi.
- Ukomisa.
- Ukwehluleka kokuphefumula.
- Izifo ezithathelwanayo.
- I-Lactic acidosis.
- Isifo sikashukela sikashukela.
- I-acute myocardial infarction (umlando).
- Ukudla kwe-Hypocaloric (ngaphansi kwama-kilocalories ayi-1000 ngosuku).
- Ukukhulelwa nokukhulelwa.
Lapho usebenzisa umuthi, ukuphazamiseka ekusebenzeni kwamgudu wokugaya ukudla, i-CCC kanye nohlelo lwe-hematopoietic lungakhula. Kusenethuba lokuphazamiseka kwe-metabolic. Imvamisa, imiphumela emibi ivela ne-overdose.
Ividiyo ekulesi sihloko ikhuluma ngohlangothi oluhle nolubi lwesidakamizwa uGlucobay.
