Ifomu lomthamo: amaphilisi abushelelezi aqukethe i-metformin 500 noma 850 mg.
Ukuqanjwa kwesidakamizwa iMetfogamma 500: metformin - 500 mg.
Izingxenye ezingeziwe: i-propylene glycol, i-methylhydroxypropyl cellulose, i-magnesium stearate, i-povidone, i-polyethylene glycol 6000, i-sodium glycolate, i-titanium dioxide (E 171), i-anhydrous colloidal silicon dioxide, i-talc ehlanjululwayo, isitashi sommbila.
I-Metphogamma 850: metformin - 850 mg.
Izinto ezengeziwe: methylhydroxypropyl cellulose, macrogol 6000, povidone, titanium dioxide (E 171), magnesium stearate.
I-Metfogamm 500: ebunjiwe kahle, i-biconvex, amaphilisi amhlophe ayindilinga. Izingcezu ezingama-30 nezingama-120 iphakethe ngalinye.
I-Metphogamma 850: Amatafula abushelelezi, amatafula amhlophe aqukethe umugqa onephutha. Isidakamizwa se-Hypoglycemic.
Izinkomba zokusetshenziswa - thayipha i-mellitus yesifo sikashukela esinga-insulin engavikelekile, hhayi othambekele ku-ketoacidosis (mayelana neziguli ezikhuluphele).
Contraindication
- I-Ketoacidosis ine-diabetes.
- Isifo sikashukela sikashukela, i-precoma.
- Ukuphefumula nokuhluleka kwenhliziyo.
- Ukwephula okucacile kwesibindi nezinso.
- Ukomisa.
- I-Lactic acidosis.
- Ukuzala ingane nokuncelisa ibele.
- Uhlobo olubi lwe-myocardial infarction.
- Ukuphazamiseka kokujikeleza kobuchopho.
- Ukudakwa okungapheli kanye nezimo ezifanayo ezingavusa ukuthuthukiswa kwe-lactic acidosis.
- Ukuzwela okuphezulu kuzakhi zomuthi.
Imithamo nendlela yokuphatha
Umthamo wezidakamizwa iMetfogamma 500 unqunywa kucatshangelwa izinga likashukela egazini ngazinye. Umthamo wokuqala uvame ukuba yi-500-1000 mg (amathani ama-1-2) ngosuku, ukwanda okuqhubekayo kancane kancane komthamo kuvunyelwe ngokuya ngomphumela wokwelashwa.
Umthamo wansuku zonke weMetfogamma 500 wokulungiswa ngamaphilisi ayi-2-4. ngosuku. Umthamo ovunyelwe nsuku zonke ngu-3 g (6 t). Ukusetshenziswa kwemithamo ephezulu akusizi ukuthuthukisa amandla ezokwelashwa (ukubuyekezwa kodokotela).
Inkambo yokwelapha izidakamizwa yinde. IMetfogamm 500 kufanele ithathwe ngokudla, iphelele bese igezwa ngamanzi amancane
Umthamo wezidakamizwa iMetfogamma 850 unqunyelwe kucatshangelwa izinga likashukela egazini ngazinye. Umthamo wokuqala uvame ukuyi-850 mg (1 t) ngosuku, ukukhuphuka kancane kancane komthamo kuvunyelwe uma amandla nokubuyekezwa kukuhle.
Umthamo wansuku zonke weMetphogamma 850 wokulungiswa ngamaphilisi ayi-1-2. ngosuku. Umthamo ovunyelwe nsuku zonke ngu-1700 mg (2 t). Ukusetshenziswa kwemithamo ephezulu akuthuthukisi amandla okwelashwa.
Inkambo yokwelashwa ngeMetfogamma 850 yinde. IMetfogamma 850 kufanele ithathwe ngokudla, ithathwe yonke igezwe phansi ngenani elincane lamanzi.
Umthamo wansuku zonke wezidakamizwa ezingaphezu kwe-850 mg kufanele uhlukaniswe ngemithamo emi-2 (ekuseni nakusihlwa). Ezigulini esezikhulile, umthamo onconyiwe ngosuku akufanele udlule ku-850 mg.
Imiyalo ekhethekile:
Umuthi awukwazi ukuthathwa:
- ngezifo ezinzima;
- nokulimala;
- ngokwanda kwezifo ezingamahlalakhona zemvelaphi ethelelekayo;
- ngezifo zokuhlinzwa kanye nokwanda kwazo;
- ngokuqokwa kokwelashwa kwe-insulin.
Awukwazi ukusebenzisa umuthi ngokushesha ngaphambi kokuhlinzwa futhi izinsuku ezimbili ngemuva kwazo. Okufanayo kusebenza ekuhlolweni kwe-radiological and radiological (hhayi ezinsukwini ezi-2 ngaphambi nangezinsuku ezi-2 ngemuva).
Kuyinto engathandeki ukusebenzisa umuthi ezigulini ezilandela ukudla okuvinjelwe ikhalori (ngaphansi kuka-1000 kcal ngosuku). Awukwazi ukunikeza lesi sidakamizwa kubantu abaneminyaka engaphezu kwengu-60 abasebenzisa ukuzikhandla okukhulu ngokomzimba. Lokhu kwandisa ingozi ye-lactic acidosis.
Ngesikhathi sokulashwa konke, kuyadingeka ukuqapha ukusebenza kwezinso futhi ubheke isimo sazo. Kanye njalo ezinyangeni eziyisithupha, ikakhulukazi phambi kwe-myalgia, kuyadingeka ukunquma ukuqoqwa kwe-lactate ku-plasma.
I-Metfogamma ingasetjenziswa ngokuhlanganiswa nama-insulin noma ama-sulfonylureas. Isimo okuwukuso kuphela ukubheka ushukela wegazi.
Ukuxhumana neminye imithi
Kungenzeka ukwandisa umphumela we-hypoglycemic we-metformin uma kunqunywe ngokuhlanganiswa ne:
- b-blockers;
- cyclophosphamide;
- finyelela kokunye okususwayo;
- Ama-inhibitors e-ACE;
- oxytetracycline;
- Mao inhibitors;
- izidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala;
- insulin;
- i-acarbose;
- derivatives sulfonylurea.
Kungenzeka ukunciphisa umphumela we-hypoglycemic we-metformin lapho unqunywe ngokuhlanganiswa ne:
- i-loop ne-thiazide diuretics;
- i-nicotinic acid analogues;
- ama-hormone egilo;
- i-glucagon;
- i-sympathomimetics;
- adrenaline
- izindlela zokuvimbela inzalo ngomlomo;
- glucocorticosteroids.
Ngokusetshenziswa kanyekanye ne-cimetidine, ubungozi be-lactic acidosis buyanda. Lokhu kuchazwa iqiniso lokuthi i-cimetidine ibambezela ukukhishwa kwe-metformin emzimbeni.
I-Metformin iyakwazi ukwenza buthaka umphumela wama-anticoagulants.
Uma uthathwa ngotshwala, kunobungozi bokuthuthukisa i-lactic acidosis, leli qiniso liqinisekiswa izibuyekezo.
Imiphumela emibi
Kusuka kwipheshana lesisu:
- isifo sohudo, ukuqina kwesisu;
- isicanucanu, ukuhlanza
- ukunambitheka kwensimbi emlonyeni;
- ukulahleka kwesifiso.
Ngokuyinhloko, zonke lezi zimpawu zihamba zodwa, ngaphandle kwezinguquko zedosi. Ubukhulu nobuningi bemiphumela emibi evela emgudwini wesisu bungancipha noma unyamalale ngemuva kokukhulisa umthamo we-metformin.
Kusuka ohlelweni lwe-endocrine (lapho usebenzisa imithamo enganele), i-hypoglycemia ingaqhamuka (ukubuyekezwa kweziguli).
Ukubonakaliswa kwe-allergic: ukuqhuma kwesikhumba.
Ezimweni ezingavamile, kusuka ohlangothini lwe-metabolism, oludinga ukuyekiswa kokwelashwa, i-lactic acidosis.
Kwezinye izimo, i-hematopoiesis - i-megaloblastic anemia.
Okusongela i-overdose
I-overdose ye-Metfogamma iyingozi ngamathuba aphezulu okuthuthukisa i-lactic acidosis enomphumela obulalayo, ukubuyekezwa kungathuli. Isizathu sokuthuthuka kwalesi simo silele ekuqokeleleni kwezakhi zomuthi ngenxa yomsebenzi wezinso ongasebenzi kahle. Izimpawu zokuqala ze-lactic acidosis zibandakanya:
- ukwanda kokushisa komzimba;
- isicanucanu, ukuhlanza
- i-colic esiswini nasemisipha;
- isifo sohudo
ngokuzayo kungabonakala:
- Isiyezi
- ukuphefumula ngokushesha;
- ukwazi ukungaphili kahle, ukukhohlisa.
Kubalulekile! Ezimpawu zokuqala ze-lactic acidosis, ukwelashwa nomuthi kufanele kumiswe ngokushesha, futhi isiguli kufanele siphuthunyiswe esibhedlela, lapho kuhlaziywa khona ukuhlinzwa kwe-lactate ukuze kuqinisekiswe ukutholwa.
Ngokuthuthukiswa kwe-lactic acidosis, isilinganiso esisebenzayo kakhulu sokuhoxiswa kwe-lactate yi-hemodialysis. Kanye nalokhu, ukwelashwa okubonakalayo nakho kuyenziwa. Uma i-metfogamma 850 isetshenziswa ngokuhlanganiswa ne-sulfonylureas, kukhona ubungozi be-hypoglycemia.
Isitoreji
IMetfogamma 850 neMetfogamma 500 ivunyelwe ukulondolozwa endaweni ephakeme engaphansi kwama-25 ° C. Impilo yeshelf iyiminyaka emi-4.
Nakani! Yonke imininingwane ingeyokuholwa kuphela futhi ihloselwe odokotela. Imininingwane enemininingwane mayelana nalesi sidakamizwa isemiyalweni ehambisana nokusetshenziswa kwephakheji, futhi ukubukeza ngakho kungatholakala kwi-Intanethi
