IGlulisin ngumjovo. Kuyi-insulin emfushane futhi into esebenzayo yezidakamizwa ezithile okuhloswe ngazo ukwehlisa amazinga kashukela egazini. Isetshenziselwa ushukela, odinga ukwelashwa okuphoqelekile nge-insulin ye-hormone.
Indlela yokusebenzisa kanye ne-contraindication
I-Glulisin iyi-insulin yabantu ephindaphindayo, noma kunjalo, amandla ayo alingana nalawo we-insulin ejwayelekile yomuntu. Umuthi uqala ukusebenza ngokushesha okukhulu, kepha isikhathi esifushane. Ngemuva kwemizuzu engu-10 ukuya kwengu-20 ngemuva kokujova okufakwayo, onesifo sikashukela uzozizwa ephumule kakhulu.
Ngaphezu kwemijovo engaphansi, i-glulisin yezidakamizwa ingalawulwa ngokufakwa okuqhubekayo kumafutha angaphansi kusetshenziswa iphampu ye-insulin. Ukujova kwenziwa kangcono kungekudala noma ngemuva kokudla.
Imijovo engaphansi kufanele yenziwe ehlombe, okhalweni noma esiswini. Uma sikhuluma nge-infusions eqhubekayo, khona-ke kwenziwa kuphela esiswini.
Ukusetshenziswa kwesidakamizwa akunconywa ezimweni ezinjalo:
- iminyaka yezingane;
- i-hypoglycemia;
- ukuzwela ngokweqile.
I-Insulin Glulizin isebenza kuma-regimens okwelashwa, ahlinzeka nge-insulin yesikhathi esiphakathi noma eside. Isidakamizwa sisetshenziswa sihlanganiswa namanye ama-hypoglycemic agents ngefomethi yethebhulethi, siphinde siphathwe kusetshenziswa isirinji ye-insulin.
Ukuboniswa kokuphendula okungahambi kahle
Ukusabela okungalungile ngemuva kokusetshenziswa kwomuthi kungenzeka:
- ukuzwela ngokweqile, ngokwesibonelo, ukuvuvukala, ukulunywa kanye nokubomvu ezindaweni zokukhwabanisa. Ukuphendula okunjalo, njengomthetho, kunyamalala ngokuphelele ngokwelashwa okuhlala isikhathi eside. Kwezinye izimo, ukubonakaliswa kwe-lipodystrophy (izinkinga zesikhumba ezibangelwa ukwephulwa kokushintshaniswa kwezindawo zokulawula umuthi) kungenzeka;
- ukungezwani komzimba (ukusweleka komoya, i-dermatitis ye-allergic, i-urticaria, ukulunywa, i-spasm ku-bronchi);
- imiphumela ehlukahlukene
Amacala okweqa
Okwamanje, umuthi awunayo idatha emacaleni we-drug overdose, noma kunjalo, i-hypoglycemia yamandla ahlukahlukene kungenzeka ngokomqondo kungenzeka.
Iziqephu ze-overdose emnene zingamiswa ngokusebenzisa ushukela noma ukudla okuqukethe ushukela. Ngalesi sizathu, wonke umuntu onesifo sikashukela kufanele abe nesikhathi esincane soshukela naye.
Ngokulahlekelwa okukhulu futhi okuhambisana nokukholelwa kwe-hypoglycemia, kungenzeka ukumisa inqubo ngokuphathwa kwe-intramuscular noma i-subcutaneous ye-glucagon ne-intravenous dextrose.
Ngemuva kokuthola ukwazi kabusha, isiguli kufanele sidle ama-carbohydrate. Lokhu kuzokwenza ukuthi kuvikeleke ukukhula kabusha kwe-hypoglycemia.
Izici zokusebenzisa umuthi
Uma i-Glulisin isetshenziswa ngokuhambisana nama-ejenti alandelayo, khona-ke i-insulin ingathuthukisa umphumela we-hypoglycemic futhi ikhulise nengozi ye-hypoglycemia:
- izidakamizwa ze-hypoglycemic zomlomo;
- ama-disopyramid;
- Ama-inhibitors e-ACE;
- imicu;
- Mao inhibitors;
- ama-salicylates;
- ama-sulfonamides;
- propoxyphene.
Lapho uhlanganisa i-insulin ne-danazol, i-salbutamol, isoniazides, i-diazoxide, i-phenothiazine derivatives, i-somatropin, i-diuretics, i-epinephrine, i-terbutaline, i-proteinase inhibitors, izidakamizwa ze-antipsychotic, i-Glulizin izonciphisa umphumela we-hypoglycemic.
Ukusetshenziswa kwe-beta-blockers, usawoti we-lithium, i-ethanol ne-Clonidine kungawenza buthaka umphumela we-insulin Glulizin yezidakamizwa. IPentamidine iphinde icasule i-hypoglycemia ne-hyperglycemia ngenxa yalokho.
Ukusetshenziswa kwamalungiselelo womsebenzi wozwela uyakwazi ukufaka imaski ukubonakaliswa kwe-adrenergic reflex activation. Lokhu kufaka i-guanethidine, i-clonidine.
Uma nje isiguli sidluliselwa kuhlobo oluhlukile lwe-insulin (noma kwesinye isidakamizwa kumkhiqizi omusha), kufanele sinikezwe ukwelashwa okuqinile kwezokwelapha. Lokhu kubalulekile ekubhekeni kwesidingo esingahle silinganiswe sokwelashwa.
Imithamo engalungile ye-insulin Glulisin noma ukuyeka ukwelashwa kubangela ukukhula ngokushesha kwe-hypoglycemia ne-ketoacidosis (izimo ezingaba yingozi empilweni).
Isikhathi sokuthuthuka kwesimo se-hypoglycemic sizoya ngesivinini sokuqala kwezenzo zemithi esetshenziswayo futhi singashintsha ngokulungiswa kwerejimeni yokwelashwa.
Kunezimo ezithile ezishintsha noma zenza ama-harbinger we-hypoglycemia ezayo akhulunyelwe, ngokwesibonelo:
- isifo sikashukela se-neuropathy;
- ukuqinisa ukwelashwa nge-insulin;
- isikhathi sesifo sikashukela;
- ukusetshenziswa kwemithi ethile;
- ukudluliswa kwesiguli kusuka esilwaneni kuya kwi-insulin yomuntu.
Ushintsho kumthamo we-insulin Glulisin uyadingeka lapho ushintsha uhlobo lokudla lokudla noma ushintsha umthwalo wesiguli ngokomzimba. Ukuzivocavoca umzimba ngokushesha ngemuva kokudla iba yingozi yokuba ne-hypoglycemia.
Uma kufakwe i-insulin ebambela amafushane, ukwehla okukhulu kweglucose egazini kubonwa ngokushesha okukhulu kunalokho lapho kusetshenziswa i-insulin yomuntu encibilikayo.
I-hypoglycemia engaphendulwanga kanye nokuphendula okungama-hyperglycemic kungaba yizidingo zokulahlekelwa ukwazi, ukuqina komthambo nokufa!
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Abesifazane abakhulelwe kufanele basebenzise i-insulin Glulisin ngaphansi kokuqashwa ngudokotela futhi kuncike ekuhlolweni kwamazinga kashukela egazini.
Ngesikhathi sokuncelisa, umuthi awukwazi ukungena obisini, futhi ngenxa yalokho uvunyelwe ukusetshenziswa. Ngesikhathi sokuqunjelwa, kuyadingeka ukulungisa imithamo esetshenzisiwe yento ephethwe. Ngaphezu kwalokho, ushintsho kumthamo ungahle lube khona lapho kukhona imithwalo ethe xaxa ngokweqile kanye nokugula okufana nalokhu.
