Isifo sikashukela i-mellitus kaningi singaba ukwanda kwenkambo yokuvuvukala okungapheli kwamanyikwe. Kuyaphawuleka ukuthi inani lamacala wesifo sikashukela esincike kakhulu futhi esizimele cishe acishe afane.
Kwi-pancreatitis eyingozi, ukuguqukela esimweni se-hyperglycemia kungaphawulwa ngamaphesenti angama-50 wamacala, angama-15 kuwo ayobe ebonakala ngendlela ezinzile ye-hyperglycemia.
Ekuhambeni kwezokwelapha okuhlose ukuqeda ukuhlaselwa kwe-pancreatic, ukugcotshwa koshukela egazini lomuntu ogulayo kuzokwehla kuze kufinyelele kumaki ojwayelekile.
Izimfuneko eziphambili zokuvela kwalesi sifo
I-pancreatogenic sikashukela mellitus iba lapho ukuvuvukala kwepancreatic okungapheli kuqhubeka. Ngaphezu kwalokho, lesi sifo sihambisana nokubhujiswa kanye ne-sclerosis yezitho zomuntu zesibeletho.
Imiphumela ye-pathogenic nayo ifakwa kumaseli wezinqola zaseLangerhans. Ungathola okuningi mayelana nokuthi yikuphi ukusengwa kwamaLangerhans kuwebhusayithi yethu.
Indima ebalulekile pathogenesis yesifo sikashukela ekulimazeni okungapheli kwama-pancreas inikezwe isimo somthethosisekelo sokumelana kwezicubu. Sibonakala kakhulu salabo bantu abakhuluphele ne-hyperlipidemic.
Ukukhuluphala kuba umthwalo ophambili we-pancreatitis engapheli futhi kungathinta kabi i-prognosis yokwelashwa.
Ngokwezibalo zezokwelapha, ngesisindo somzimba esandayo, amathuba okuthi kube nezinkinga zokuvuvukala okungapheli kumanyikwe, kanye nokungasebenzi kahle kwe-endocrine. Ngaphezu kwalokho, ezigulini ezine-pancreatitis eyingozi phakathi kwesisindo somzimba ngokweqile, i-hyperglycemia ivame ukukhula.
Uma ukwanda kwenqubo yokuvuvukala kwenzeka, khona-ke kuleli cala, ukudlula kwe-hyperglycemia kuzohlotshaniswa:
- ukuvuvukala kwamanyikwe;
- Umphumela we-inhibitory we-trypsin ekukhiqizweni kwe-insulin ye-hormone (ukugcotshwa kwawo okukhuphula kakhulu ngesikhathi sokuvuvukala okukhulu kanye nokwanda).
Izithombe zemitholampilo
I-pancreatitis kanye nesifo sikashukela kuyinhlanganisela enkulu yezifo. Ukungalingani ekubekezeleleni i-carbohydrate kuyinto ebonakala ekuqaleni kwe-pancreatitis engamahlalakhona. Njengomthetho, ukwephulwa okuqhubekayo kwe-carbohydrate metabolism kubhekwa cishe iminyaka emi-5 ngemuva kokuqala kokugula okungaphansi.
Ukuphazamiseka kokusebenza kwe-endocrine ekuvuvukeni okungapheli kungabonakala ngezindlela ezimbili:
- i-hypoglycemia (hyperinsulinism);
- ushukela we-pancreatogenic.
I-Hyperinsulinism ingenzeka ngezimpawu zobuntu ezihambisana nalokhu:
- indlala;
- umjuluko obandayo;
- ubuthakathaka bemisipha;
- ukuthuthumela emzimbeni wonke;
- injabulo eyeqisayo.
Cishe ingxenye yesithathu yamacala e-hypoglycemia, ukwehluleka kanye nokulahlekelwa ukwazi.
I-pancreatogenicabetes mellitus inezici eziningi:
- lesi sifo sithinta, njengomthetho, iziguli ezacile ezinomhlobo wohlobo lwe-choleric;
- lesi sifo asihlotshaniswa nesisindo ngokweqile, ukubekezelela ushukela noma ukubekeka phambili komndeni;
- kulesi simo, i-hyperglycemia ibekezelelwa kalula, kufinyelela ezingeni le-11.5 mmol / l;
- isifo sikashukela i-mellitus sidlula ngendlela emnene futhi asikho isidingo se-insulin yendabuko ngokumelene nesizinda sokuncipha kokudla kokudla kwe-caloric, kanye ne-malabsorption;
- kunezimpawu zezimpawu zesifo sikashukela eminyakeni embalwa nje ngemuva kokubona ukuhlaselwa kokuqala kobuhlungu emgodini wesisu;
- kunokuthambekela kwe-hypoglycemia;
- imvamisa yesikhumba, kanye nezifo ezithathelanayo;
- Kamuva nje kunokuvela kwesifo sikashukela se-classical: ketoacidosis; izimo ze-hyperosmolar, microangiopathy;
- lesi sifo singasebenza kakhulu ekwelapheni ngosizo lokondleka okhethekile, ukusebenza ngokomzimba kanye namalungiselelo we-sulfonylurea;
- isidingo se-insulin eyengeziwe asibonakali.
Ukuxilongwa nokwelashwa
Ukutholwa kwesifo sikashukela se-pancreatogenic kungenzeka uma kwenziwa ukuhlola kwezifo zakudala.
Ukuqeda lesi sifo, kufanele kuthuthukiswe umsoco ofanele wokudla. Kubalulekile ukunaka ngokukhethekile ukulungiswa kokuntuleka kwamaprotheni-amandla, kanye nokuthola isisindo. Ngaphezu kwalokho, akunakwenzeka ukwenza ngaphandle kokujwayelekile kwe-hypovitaminosis nokuphazamiseka kwe-electrolyte.
Ukungapheleli kwepancreatic pancreatic kufanele kunxephezelwe kahle ngangokunokwenzeka. Lokhu kudinga ukuqokwa kwamalungiselelo we-enzyme yesitho esithintekile.
Akubalulekanga kangako odabeni lokunciphisa izinhlungu emgodini wesisu okuzoba ukusetshenziswa okuphoqelekile kwama-analgesics wemvelaphi engeyona eye-narcotic.
Uma udokotela ezoncoma ukungenelela kokuhlinzwa, khona-ke kuleli cala kubalulekile ukuvikela i-palreatomy ye-distal. Uma kunesidingo, kuzobekwa imithamo emincane ye-insulin elula. Kungumthamo ongekho ngaphezu kwama-30 amayunithi. Imithamo ngqo izoncika ngokuphelele kuzimpawu ezinjalo:
- ukugxila kweglucose egazini;
- imvelo yokondleka;
- izinga lomsebenzi womzimba;
- inani lama-carbohydrate aqediwe.
Awungehlisi izinga le-glucose egazini, uma luphawu olungezansi kuka-4.5 mmol / L. Ngaphandle kwalokho, i-hypoglycemia ingaqala ukukhula.
Lapho nje izinkomba ze-carbohydrate metabolism sezizinzisiwe, isiguli kufanele sidluliselwe emithini yomlomo okuhloswe ngayo ukwehlisa amazinga kashukela wegazi.
