I-Ranitidine umuthi obulala izinzwa ovimbela ukwenziwa kwejusi lesisu. I-hydrochloric acid ethe xaxa ene-pancreatitis exacerbated chronic iyokwakha izimo ezinhle zokuthuthuka kwenqubo yokuvuvukala.
Mayelana nomuthi
I-Ranitidine ithole ukuthandwa ngobuningi kuma-80s eminyaka edlule. Ngaleso sikhathi, lesi sidakamizwa sasiqashelwa njengesisebenza ngempumelelo kakhulu ekwelapheni izifo ezibangelwa yi-acid zohlelo lokugaya, kufaka phakathi i-pancreatitis. Umphumela omkhulu wemitholampilo we-ranitidine ukwehla kwethamo lawo wonke ujusi we-gastric kanye nokwehla kwesikhumba se-pepsin.
Isenzo somuthi sihlala amahora angama-12, kepha sithambekele ukuqongelela (ukuqongelela): ngalokho-ke, amaphesenti angama-40 kuphela omthamo owamukelekile we-ranitidine asuswa emzimbeni ngosuku.
Iziguli ezinokwehluleka kwezinso kufanele zilinganise ngokucophelela umthamo noma zenqabe umuthi, bese ukhetha enye esikhundleni salokho.
I-Ranitidine ibonakala ngomphumela we "rebound", ozibonakalisa ngemuva kokusetshenziswa isikhathi eside, bese ukwehluleka okubukhali. Ezimweni ezinjalo, ukwanda okubukhali ekukhiqizeni ujusi we-gastric kungenzeka futhi, ngenxa yalokho, ukushisa kwenhliziyo nokuqala kobuhlungu esiswini.
Isidakamizwa se-pancreatitis
Ngaphandle kokuvela kwemithi yesimanje embonini yezemithi, odokotela abaningi bayaqhubeka nokusebenzisa i-ranitidine ukwelapha i-pancreatitis engapheli.
Uhlobo lokukhululwa kwe-ranitidine lomjovo ngama-ampoules angama-50 mg-2 ml. Ngosuku lokuqala lokunakekelwa kwesiguli esibhedlela, umuthi uphathwa kahle amahlandla ama-3 ngosuku, ama-50 mg lilinye. Okuqukethwe kwe-ampoule kuhlanjululwe ngesisombululo se-isotonic ku-10 ml futhi kancane (imizuzu emi-2, okungenani) kufakwe emthanjeni.
Ukuphathwa kokudonsa i-ranitidine ngendlela yokumiliselwa okuhlala amahora amabili kuvunyelwe. I-ampoule eyodwa ixutshwe ne-isotonic sodium chloride ngesilinganiso esingu-200 ml. Kwezinye izimo, imijovo ye-intramuscular njalo emahoreni angama-6-8 kuma-50 mg inqunyelwe.
Ngakho-ke, emahoreni okuqala okwanda kokuvuvukala okungapheli kwamanyikwe, kukhona ukwehla kokugcinwa kwesisu kanye nokwehla komthwalo osesiswini. Lokhu kubaluleke kakhulu, ngoba ngosuku lokuqala lokwanda isiguli kwesinye isikhathi asidli lutho.
Inani elincane lokuphepha esiswini linciphisa umsebenzi wezigaba ezilandelanayo zeketheni lokugaya. I-excretion yejusi ye-pancreatic nayo iyancishiswa, futhi lokhu kuyathandeka kakhulu esigabeni esibuhlungu.
Kakade ngosuku lwesibili lokulaliswa esibhedlela, isiguli sidluliselwa ku-ranitidine ezibhebheni. Imvamisa, amacebo anjalo asetshenziswa:
- ekuseni nakusihlwa, noma mhlawumbe emva kwamahora ayi-12 - ama-150 mg lilinye;
- ngokubona kukadokotela, umuthi ungabekwa amahlandla ama-3 ngosuku, ama-150 mg lilinye;
- kanye ngosuku ebusuku - 300 mg (inani eliphakeme lokukhuphuka kwesisu lenzeka ngokunembile ebusuku);
Umthamo omkhulu we-ranitidine wansuku zonke akufanele udlule ku-600 mg. Ngenxa yesifo se-rebound esishiwo ngenhla, i-ranitidine idinga ukuhoxa njalo. Ngaphandle kwalokho, isiguli singase sibe sibi kakhulu.
Ngemuva kokunciphisa ukubhebhetheka kwe-pancreatitis engapheli, kwesinye isikhathi odokotela basebenzisa inhlanganisela yamalungiselelo we-ranitidine kanye ne-enzyme yokulungiselela i-pancreas. Lesi sikimu siyasebenza ekungapheleni kwe-pancreatic. Ngokusho kwezifundo zobudokotela, isenzo salawa ma-enzyme ekusindweni okucindezelwe esiswini kubhekwa njengokusebenza kakhulu.
Iziguli eziningi ezine-pancreatitis engapheli ziba nenkinga efana ne-Reflux esophagitis. Kulesi simo, ukwelashwa okuhlala isikhathi eside nge-ranitidine kunqunyelwe (amaviki ama-6-8), kusetshenziswa uhlelo olujwayelekile - 150 mg ekuseni nakusihlwa.
- I-Ranitidine ithathwa ngaphandle kokubheka ukudla.
- Ithebhulethi ligwinye ligcwele, ligezwe ngenani elincane lamanzi.
- Ithebhulethi ye-effeedcent iphonswa emanzini bese uketshezi luphuzwa kuphela uma umuthi usuchithiwe ngokuphelele.
Uma isiguli sinqunyelwe ama-antacid anjenge-maalox noma i-almagel, khona-ke kufanele kube nokuphumula okungamahora amabili phakathi kwawo ne-ranitidine.
Imiphumela emibi ye-ranitidine
Akunconywa ukuthatha umuthi uwedwa nge-pancreatitis, ngoba imiphumela yayo emibi mibi kakhulu:
- isiyezi, ikhanda elibi, ukwazi okufiphele;
- isifo sohudo, ukuqunjelwa, isicanucanu, ukuhlanza;
- imisipha nobuhlungu obuhlangene;
- ukuphazamiseka kwesigqi senhliziyo.
- ukungezwani komzimba - i-edema kaQuincke, i-dermatitis;
- ukulahlekelwa izinwele
- ukwehluleka kwesibindi;
- ukukhulisa amabele emadodeni (gynecomastia) nokusetshenziswa isikhathi eside;
- ukuphazamiseka emjikelezweni wokuya esikhathini;
- kwehle i-libido ne-potency.
Contraindication
I-Ranitidine i-contraindified:
- ngesikhathi sokukhulelwa;
- ngenkathi uncelisa ibele;
- ngaphansi kweminyaka eyi-12.
Ngaphambi kokunquma umuthi, ukungafaki i-adenocarcinoma ye-gastric, i-fibrogastroscopy kufanele yenziwe. Lokhu kuyadingeka ngoba ukuphathwa isikhathi eside kwe-ranitidine kungavimba umtholampilo womdlavuza, kufihla izimpawu zomdlavuza we-pancreatic, izimpawu zokuqala.
I-Ranitidine inganikeza isivivinyo esingelona iqiniso samaprotheni kumchamo kanye ne-amphetamine, (abashayeli kufanele bazi ngalokhu) Umlutha weNicotine unciphisa umphumela wokuphulukisa we-ranitidine.
