Omunye wemithi esekelwayo esetshenziselwa isifo sikashukela yiTricor. Akusebenzi izidakamizwa ze-hypoglycemic, kepha kunganciphisa kancane izinga le-glucose egazini.
Ukuqonda ukuthi uyisebenzisa kanjani ngendlela efanele, udinga ukuthola indawo esemqoka yokusetshenziswa kwayo kanye nezimpawu eziphambili.
Imininingwane ejwayelekile, ukwakheka kanye nendlela yokukhululwa
Ngokusho kwe-radar, uTricor umuthi okwehlisa i-lipid - ovela ku-cholesterol esegazini. Ukusetshenziswa kwaso kusiza ukunciphisa inani lamafutha emzimbeni futhi kuvimbela ukwakheka kwe-atherosclerosis.
Ukukhishwa kwayo kwenziwa eFrance, lapho lesi sidakamizwa sithengiswa khona ngamaphilisi. Umphumela wesidakamizwa kungenxa yengxenye eyinhloko, okuyi-fenofibrate.
Ungayisebenzisa kuphela njengoba kuyalelwe udokotela, ngoba inamandla amakhulu emzimbeni. Ukungahambi kahle okungathi sína kungenzeka uma kudliwe ngokungadingekile. Ngakho-ke, kungenzeka ukuyithenga kuphela ngokubhaliwe.
Ukukhiqizwa kwemali kwenziwa ezibhebheni. Isithako esisebenzayo somuthi yi-fenofibrate. Ifakwe kumathebhulethi ngenani le-145 mg.
Ngaphezu kwakho, kunezakhi ezifana:
- sucrose;
- i-hypromellose;
- idokhumenti yesodium;
- i-magnesium stereate;
- i-microcrystalline cellulose;
- i-lactose monohydrate;
- i-sodium laurisulfate;
- i-silicon dioxide colloidal.
Lezi zinto zikuvumela ukuthi unikeze umuthi ijamo oyifunayo. Izibhebhezo zenziwe ngefilimu (i-bp).
Kukhona futhi amaphilisi anokuqukethwe okusebenzayo kwe-160 mg. Ziqukethe izingxenye ezengeziwe ezifanayo njengolunye uhlobo lomuthi.
Amaphakethe womuthi anezilungiselelo ezihlukile. Zingahlanganisa amaphilisi ayi-10 kuye kwangama-300 (umthamo we-145 mg) noma kusuka kwezingcezwana ezi-10 kuye kwezingu-100 (umthamo we-160 mg).
Isenzo se-Pharmacological ne-pharmacokinetics
Ukuqonda ukuthi lo muthi uhloselwe ini, udinga ukuthola izici zesenzo sawo.
I-Fenofibrate inomphumela kuma-triglycerides, anciphisa inani labo. Kuyasiza futhi ukwehlisa i-cholesterol egazini. Lokhu kungenxa yokwephulwa kokuhlanganiswa kwamafutha acid.
Ukusetshenziswa kwomuthi kunganciphisa inani le-fibrinogen. Ingxenye esebenza ngokubuthakathaka kancane isebenza ku-glucose, isiza ukunciphisa izinga layo. Lezi zici zenza i-Tricor isebenze ngempumelelo ekwelapheni iziguli ze-atherosclerosis ezinomkhuba wokuthuthukisa isifo sikashukela.
I-Fenofibrate ifinyelela kumphumela wayo omkhulu emahoreni angama-5 ngemuva kokuphatha (lokhu kuthonywa izici zomzimba ngamunye).
Inani elikhulu lazo lihlangana ne-albhamuin, iprotheni ye-plasma, yakha i-fenofibroic acid. Imetabolism yayo yenziwa esibindini. Umuthi unomphumela ohlala isikhathi eside - cishe amahora angama-20 ayadingeka ukususa uhhafu wawo. Kushiya umzimba ungene emathunjini nasezinso.
Izinkomba kanye ne-contraindication
Ungathola ukuthi leli thuluzi lisiza ini ngokufunda imiyalo nezinkomba zenhloso yayo.
Kunconywa ukuyisebenzisela ukwephulwa okunjengokuthi:
- hypercholesterolemia;
- i-hypertriglyceridemia;
- hyperlipoproteinemia.
Ngezifo ezinjalo, iTricorr iyasetshenziswa uma izindlela zokwelapha ezingezona izidakamizwa zilethi imiphumela.
Futhi, udokotela angabeka lesi sidakamizwa ukunqoba ezinye izifo njengengxenye yokwelashwa okuyinkimbinkimbi, uma ngabe lezo zenzo kufanelekile.
Kumele kukhunjulwe ukuthi ukuba khona kwezinkomba zokuthola umuthi kusho ukuthi ukusetshenziswa okuphoqelekile kwalo muthi. Ukutholwa kwe-contraindication kukuphoqa ukuthi uyeke ukusetshenziswa kwayo.
Lokhu kufaka phakathi:
- izifo ezinzima zesibindi;
- izinkinga ezinkulu zezinso;
- ukungabekezeleli ekwakhekeni;
- ukucaphuka
- isifo se-gallbladder;
- iminyaka yezingane.
Kukhona futhi izimo lapho ukusetshenziswa kweTricor kuvunyelwe, kepha kudinga ukuqaphela okwengeziwe:
- utshwala;
- i-hypothyroidism;
- ubudala
- ukwephula esibindini nasezinso.
Lokhu kusho ukuthi ungathatha lo muthi kuphela ngokuyalelwa uchwepheshe. Ukuzelapha kungakuholela ezinkingeni.
Imiyalo yokusebenzisa
IMans Tricor isetshenziswa kuphela ngaphakathi. Lapho usebenzisa umuthi kumthamo we-145 mg, ungawuphuza ngaphandle kokudla. Uma kuthathwa umthamo we-160 mg, umuthi kufanele uphuzwe nokudla. Awudingi ukugaya nokuhlafuna amaphilisi, kungakuhle ukuligeze ngamanzi anele.
Imithamo nohlelo lokuphatha luvame ukubekwa uchwepheshe ngemuva kokufunda isithombe sesi sifo nama-pathologies ahambisana nawo. Uma izimo ezidinga ukulungiswa kwayo zingekho, isiguli sinconywa ukuthatha i-145 noma i-160 mg (1 ithebhulethi) ngosuku.
Isikhathi senkambo yokwelashwa sinqunywa futhi ngamunye. Ezimweni eziningi, kuthatha isikhathi eside. Ngaphezu kwalokho, kunconywa ukudla. Ukusebenza kwezokwelapha kunqunywa yimiphumela yokuhlolwa ukuthola inani le-cholesterol ne-triglycerides.
Noma umuthi ubekwe nguchwepheshe, isiguli kufanele siqaphe ngokucophelela izinguquko esimweni sakhe. Ukuvela kokuphendula okungalungile noma ukungabi bikho komphumela kusho ukuthi uTricor akasilungele lesi simo. Kungakhombisa isidingo sokulungiswa komthamo noma ukuba khona kwe-contraindication efihlekile.
Ividiyo ephathelene ne-cholesterol nemisebenzi yayo emzimbeni:
Iziguli Ezikhethekile Nezinkomba
Inani leziguli kunconywa ngalo ukuqaphela okuthile lapho usebenzisa uTricor emaqenjini alandelayo abantu:
- Abesifazane ngesikhathi sokukhulelwa. Umuthi osebenzayo wesidakamizwa ubekelwe wona, ngenxa yalokho, ngalesi sikhathi ukusetshenziswa kwawo kwenqatshelwe.
- Omama abahlengikazi. Izici zomphumela we-fenofibrate kukhwalithi yobisi lwebele nakwengane azikasungulwa. Kulokhu, odokotela abayisebenzisi iTrikor kulezi ziguli.
- Izingane. Eminyakeni engu-18, lesi sidakamizwa asisetshenziswa, ngoba akwaziwa ukuthi ukuqanjwa kwaso kungawuthinta kanjani umzimba wezingane.
- Abantu abadala. Kulesi sigaba seziguli, ukusetshenziswa komuthi kubhekwa njengento eyamukelekayo. Kepha ngaphambi kokuqokwa kwakhe, iziguli zidinga ukuhlolwa ukuze kugwenywe izinkinga ezingaba khona. Ukunciphisa umthamo kuyenziwa futhi.
Abanye abantu (uma kungekho contraindication) bangasebenzisa umuthi njengoba ubekiwe ngudokotela.
Kufanele kuqashelwe lapho usebenzisa iTraicor lapho kukhona ukuphazamiseka okulandelayo emzimbeni:
- Isifo sezinso. Kwezifo ezinzima zalesi sitho, ukusetshenziswa komuthi akuvunyelwe. Ukuchezuka okuncane ekusebenzeni kwezinso kudinga ukuqashwa njalo kwenkambo yokwelashwa nokusetshenziswa kwayo.
- Isifo sesibindi. Ngezinkinga ezincane zesibindi, udokotela anganquma uTricor ngemuva kokuhlolwa. Ukwephula okubalulekile kuyisizathu sokwenqaba umuthi.
I-Fenofibrate ingathinta ukusebenza kwesibindi, ngakho-ke noma ngabe kungekho ukuphazamiseka kule ndawo, udinga ukubheka isimo sayo ngezikhathi ezithile. Futhi, ngaphansi kwethonya lomuthi, amapharamitha we-coagulation wegazi angashintsha - lokhu futhi kudinga ukulawulwa.
Imiphumela emibi kanye ne-overdose
Uma usebenzisa i-Tricorr, imiphumela emibi ingavela. Ngokuqina okukhulu, kufanele wenqabe ukwelashwa nalesi sidakamizwa.
Imiphumela emibi yesidakamizwa ihlanganisa:
- isicanucanu
- ikhanda
- izicubu zomsipha;
- ukwanda kwesibalo esimhlophe segazi;
- ukwanda kwegesi;
- isifo sohudo
- Ubuhlungu besisu
- i-myositis;
- i-urticaria;
- i-pancreatitis
- ukulunywa
- imivimbo yesikhumba;
- ukwakheka kwamatshe ayizimbi;
- i-alopecia;
- kunciphise ukwenza ucansi.
Uma kunesidingo, udokotela kufanele abhekane nabo. Ayikho i-antidote ethile, ngakho-ke, iziguli zinikezwa ukwelashwa okubonakalayo.
Amacala okweqa awakaqoshwa. Kuphakanyiswa ukuthi ukwelashwa okubonakalayo kufanele kusize ekutholeni kwayo.
Ukusebenzisana kwezidakamizwa kanye nama-analog
Ukwelashwa ngobuchule kubandakanya ukuhlanganiswa okuyikho kwezidakamizwa ezisetshenziswayo. Uma umuntu elungisa enye edukisa enye, imiphumela ingaba yimbi kakhulu. Ngakho-ke, udinga ukubheka ukuthi iTricor ingathinta kanjani leyo mithi esetshenziswa ngokuhambisana nayo.
Ukuqapha kudinga ukuhlanganiswa kwalesi sidakamizwa no:
- ama-anticoagulants (i-fenofibrate ivame ukukhulisa ukusebenza kwawo, okudala ingozi yokopha);
- I-cyclosporine (umsebenzi wezinso ungakhubazeka);
- ama-statin (kunengozi yemiphumela enobuthi emisipha).
Kwezinye izidakamizwa, ushintsho olukhulu alubonwa. Noma kunjalo, isiguli kufanele sazise udokotela ngayo yonke imishanguzo eyisebenzisayo ukuze uchwepheshe akwazi ukunikeza ukwelashwa okufanele.
Izizathu zokusebenzisa amathuluzi we-analog zingahluka. Imvamisa, iziguli zifuna ama-analogues ashibhile, ngoba ukuthatha umuthi obizayo ngokuqhubekayo kuwumsebenzi obiza kakhulu.
Abanye bakhathazekile ngemiphumela emibi eyenza kube nzima kubo ukuthi basebenze ngokugcwele. Kulokhu, ochwepheshe ngokuvamile kufanele bakhethe izidakamizwa ezinomphumela ofanayo.
Lokhu kufaka phakathi:
- I-Trilipix;
- I-Lipanor;
- Ukuqothuka;
- ICanon;
- Gemfibrozil.
Ezinye zalezi zimali zinengqikithi efana naleyo kaTraicor. Kwabanye, umphumela ofanayo uyisici, ngaphandle kokwehluka kwezakhi.
Ukuze usebenzise i-analogue, kufanele uthintane nodokotela wakho. Ukuzelapha okwenzeka njalo kuyingozi, ngakho-ke kudingeka uqiniseke ukuthi umuthi okhethiwe ulungele isiguli esithile.
Umbono wesineke
Ukubuyekezwa mayelana neTricor yezidakamizwa kuhle kakhulu - abaningi bayawubona umphumela wayo omuhle emzimbeni kanye nokwehlisa i-cholesterol yegazi.
Saw Tricor ezinyangeni eziyisithupha ezedlule njengoba kushiwo udokotela. Ngibonga, wasusa izinhlungu ezinyaweni nasemadolweni. Umfutho wegazi lami wehlile, futhi ama-triglycerides ami ancipha. Wazizwa kahle waze wayeka ukuyithatha. Zonke izimpawu zabuya, ngakho-ke ngicabanga ukucela udokotela isifundo sesibili.
UJulia, oneminyaka engama-37
Umuthi wangisiza ukuba ngiqede inkinga ye-cholesterol ephezulu. Kodwa ngenxa yakhe, ngathuthukisa i-bronchitis - ngokusobala, uhlobo oluthile lomthelela omubi. Kwakudingeka ukwenqaba ukusetshenziswa.
UYuri, oneminyaka engama-35
Sekuphele izinyanga ezintathu ngisebenzisa lo mkhiqizo. Ekuqaleni awuzange ube nomphumela omuhle, ubuthakathaka kanye nokulimala ekhanda kuphela. Bese konke kubuyela kokujwayelekile, izivivinyo zathuthuka. Ubuhlungu emilenzeni nasezingalweni babuye bama, kanye nokuqina kwanyamalala. Bengihlala ngivuka ebusuku ngenxa yabo, kepha manje lokhu akwenzeki. Ngizizwa nginamandla amakhulu - kungathi ngivuselelekile.
UDaria, oneminyaka engama-53 ubudala
Izindleko zomuthi zincike kumthamo wezithako ezisebenzayo eziqukethwe kuwo nenani lezibhebhe ezikuphakeji. Ngephakheji enamathebhulethi angama-30 (145 mg) udinga ukunikela kusuka ku-750 kuya kuma-ruble angama-900. Ngomthamo we-160 mg kanye nokupakishwa okufanayo, intengo yeTricor izosuka ku-850 kuya ku-1100 ruble.
