Ukwehla kwezidakamizwa ze-cholesterol eTorvakard - imiyalo esetshenzisiwe

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Ekwelashweni kwesifo sikashukela, akusetshenziswa izidakamizwa ezithinta kuphela ushukela osegazini.

Ngaphezu kwalokhu, udokotela wakho angakunikeza imithi esisiza ukwehlisa i-cholesterol.

Omunye umuthi onjalo yiTorvacard. Udinga ukuqonda ukuthi ingaba wusizo kanjani kubantu abanesifo sikashukela nokuthi bangayisebenzisa kanjani.

Imininingwane ejwayelekile, ukwakheka, indlela yokukhululwa

I-Statin Cholesterol Ukuvinjwa

Leli thuluzi lingenye yama-statins - imithi yokwehlisa i-cholesterol yegazi. Umsebenzi wawo oyinhloko ukunciphisa ukugcwala kwamafutha emzimbeni.

Isetjentiswa kahle ekuvimbeleni nasekulweni ne-atherosulinosis. Ngaphezu kwalokho, iTorvacard iyakwazi ukwehlisa inani loshukela egazini, elibalulekile ezigulini ezinobungozi bokuthola isifo sikashukela.

Isisekelo somuthi yinto i-Atorvastatin. Ihlangana nezithako ezingeziwe kuqinisekisa ukufinyelelwa kwezinjongo.

Kukhiqizwa eCzech Republic. Ungathenga umuthi kuphela ngesimo samathebulethi. Ukuze wenze lokhu, udinga incwadi kadokotela evela kudokotela wakho.

Ingxenye esebenzayo inomphumela obonakalayo esimweni sesiguli, ngakho-ke ukuzilapha nayo akwamukeleki. Qiniseka ukuthi uthola imiyalo ngqo.

Umuthi lo uthengiswa ngendlela yepilisi. Isithako sabo esisebenzayo yi-Atorvastatin, inani laso esigabeni ngasinye singaba ngu-10, 20 noma 40 mg.

Kuhlanganiswe nezinto ezisizayo ezithuthukisa isenzo se-Atorvastatin:

  • i-magnesium oxide;
  • i-microcrystalline cellulose;
  • i-silicon dioxide;
  • i-croscarmellose sodium;
  • i-lactose monohydrate;
  • i-magnesium stereate;
  • i-hydroxypropyl cellulose;
  • i-talc;
  • i-macrogol;
  • titanium dioxide;
  • hypromellose.

Amathebhulethi ayindilinga futhi anombala omhlophe (noma ocishe ube mhlophe). Zibekwe emabhulini angama-10 ama-pcs. Ukupakishwa kungafakelwa ama-3 noma ama-9 blisters.

I-Pharmacology ne-pharmacokinetics

Isenzo se-atorvastatin ukuvimbela i-enzyme ehlanganisa i-cholesterol. Ngenxa yalokhu, inani le-cholesterol liyancipha.

Ama-cholesterol receptors aqala ukusebenza ngokuzikhandla, ngenxa yokuthi i-complements esegazini idliwa ngokushesha okukhulu.

Lokhu kuvimbela ukwakheka kwama-atherosclerotic deposits emikhunjini. Futhi, ngaphansi kwethonya le-Atorvastatin, i-triglycerides ne-glucose iyancipha.

I-Torvacard inomphumela osheshayo. Ithonya lesakhi salo esisebenzayo lifinyelela ubukhulu baso ngemuva kwamahora angu-1-2. I-Atorvastatin icishe ibopha ngokuphelele amaprotheni e-plasma.

I-metabolism yayo yenzeka esibindini ngokwakhiwa kwama-metabolites asebenzayo. Kuthatha amahora ayi-14 ukukuqeda. Umuthi ushiya umzimba nge-bile. Umphumela wayo uphikelela amahora angama-30.

Izinkomba kanye ne-contraindication

I-Torvacard iyanconywa emacaleni alandelayo:

  • cholesterol ephezulu;
  • inani elandisiwe lama-triglycerides;
  • hypercholesterolemia;
  • izifo zenhliziyo ngengozi yokuhlaselwa yisifo senhliziyo;
  • amathuba okuqanjwa kwe-myocardial yesibili.

Udokotela angabeka lesi sidakamizwa kwezinye izimo, uma ukusetshenziswa kwaso kuzosiza ukuthuthukisa inhlalakahle yesiguli.

Kepha ngenxa yalokhu kuyadingeka ukuthi isiguli singenazo izici ezilandelayo:

  • isifo esibucayi sesibindi;
  • ukuntuleka kwe-lactase;
  • ukungabekezeleli i-lactose noshukela;
  • iminyaka engaphansi kweminyaka eyi-18;
  • ukungabekezelelani kwezakhi;
  • ukukhulelwa
  • ukondla kwemvelo.

Lezi zici ziyi-contraindication, ngenxa yokuthi ukusetshenziswa kweTorvacard kunqatshelwe.

Futhi, imiyalo ikhuluma ngamacala lapho ungasebenzisa leli thuluzi kuphela ngokuqashwa njalo kwezokwelapha:

  • utshwala;
  • i-arterial hypertension;
  • isithuthwane
  • ukuphazamiseka kwe-metabolic;
  • isifo sikashukela mellitus;
  • sepsis
  • ukulimala okungathi sína noma ukuhlinzwa okukhulu.

Ngaphansi kwezimo ezinjalo, lo muthi ungadala ukusabela okungalindelekile, ngakho-ke kudingeka ukuqapha.

Imiyalo yokusebenzisa

Kuphathwa ngomlomo kuphela kwesidakamizwa esenziwa. Ngokuya ngezincomo ezijwayelekile, esigabeni sokuqala udinga ukuphuza umuthi ngenani le-10 mg. Kwenziwa ezinye izivivinyo, ngokuya ngemiphumela udokotela angayinyusa le dosi iye kuma-20 mg.

Inani elikhulu leTorvacard ngosuku ngu-80 mg. Ingxenye esebenza kahle kakhulu inqunywa ngawodaba ngalunye.

Ngaphambi kokuwasebenzisa, amaphilisi awadingi ukuchobozekwa. Isiguli ngasinye sizithatha ngesikhathi esikahle, zingagxili ekudleni, ngoba ukudla akuthinti imiphumela.

Isikhathi sokwelashwa sinokuhluka. Umphumela othile ubonakala ngemuva kwamasonto amabili, kepha kungathatha isikhathi eside ukululama ngokuphelele.

Indaba yevidiyo evela kuDkt Malysheva mayelana nama-statins:

Iziguli Ezikhethekile Nezinkomba

Kwezinye iziguli, izingxenye ezisebenzayo zomuthi zingenza ngendlela engajwayelekile.

Ukusetshenziswa kwayo kudinga ukuqaphela maqembu alandelayo:

  1. Abesifazane abakhulelwe. Ngesikhathi sokukhulelwa, i-cholesterol kanye nalezi zinto ezihlanganiswe kuzo ziyadingeka. Ngakho-ke, ukusetshenziswa kwe-atorvastatin ngalesi sikhathi kuyingozi enganeni enezinkinga zokukhula. Ngokufanelekile, odokotela abancomi ukwelashwa ngaleli khambi.
  2. Omama abaqhuba ezondla ngokwemvelo. Ingxenye esebenzayo yesidakamizwa idlulela ebisini lwebele, olungathinta impilo yengane. Ngakho-ke, ukusetshenziswa kweTorvacard ngesikhathi sokuncelisa ibele akuvunyelwe.
  3. Izingane nentsha. Indlela u-Atorvastatin enza ngayo kubo ayaziwa kahle. Ukugwema izingozi ezingaba khona, ukuqokwa kwalo muthi kukhishwe ngaphandle.
  4. Abantu bobudala. Umuthi ubathinta kanye nanoma yiziphi ezinye iziguli ezingenazo izinto eziphikisayo ekusebenziseni kwawo. Lokhu kusho ukuthi ezigulini esezikhulile asikho isidingo sokulungiswa komthamo.

Azikho ezinye izindlela zokuvikela lo muthi.

Umgomo wezenzo zokwelapha uthonywe yinto efana nama-concomitant pathologies. Uma kutholakala, kwesinye isikhathi kudingeka ukuqapha okwengeziwe ekusebenziseni izidakamizwa.

KuTorvacard, ama-pathologies anjengalawa:

  1. Isifo sesibindi esisebenzayo. Ukuba khona kwabo kuphakathi kokuphikisana nokusebenzisa umkhiqizo.
  2. Ukwanda komsebenzi we-serum transaminases. Lesi sici somzimba sisebenza njengesizathu sokwenqaba ukuphuza umuthi.

Ukuphazamiseka emsebenzini wezinso, okuvame ukufakwa ohlwini lwe-contraindication, akuveli lapho kulokhu. Ukuba khona kwabo akuwuthinti umphumela we-Atorvastatin, ukuze iziguli ezinjalo zivunyelwe ukuthatha umuthi noma ngaphandle kokulungiswa komthamo.

Isimo esibaluleke kakhulu ukusetshenziswa kwezindlela zokuvimbela inzalo ekwelapheni abesifazane besikhathi sokuzala nezingane ngaleli thuluzi. Ngesikhathi sokuphathwa kweTorvacard, ukuqala kokukhulelwa akwamukeleki.

Imiphumela emibi kanye ne-overdose

Uma usebenzisa iTorvacard, imiphumela emibi elandelayo ingahle ivele:

  • ikhanda
  • ukuqwasha
  • ukudangala komoya;
  • isicanucanu
  • ukuphazamiseka emsebenzini wokugaya ukudla;
  • i-pancreatitis
  • ukwehla kwesifiso sokudla;
  • imisipha nobuhlungu obuhlangene;
  • iminyakazo
  • ukwethuka kwe-anaphylactic;
  • ukulunywa
  • imivimbo yesikhumba;
  • ukuphazamiseka kwezocansi.

Uma kutholakala lokhu kanye nokunye ukwephula umthetho, kufanele uthintane nodokotela wakho bese uchaza inkinga. Imizamo yokuzimela yokuyiqeda ingaholela ezinkingeni.

I-overdose nokusetshenziswa kahle kwesidakamizwa kungenzeka. Lapho kwenzeka, kuboniswa ukwelashwa okubonakalayo.

Ukuxhumana neminye imithi

Ukugwema ukusabela okungekuhle komzimba, kuyadingeka ukuthi unake ubuntu bokuthi ezinye izidakamizwa zithathwe ekusebenzeni kahle kweTorvacard.

Ukuqapha kuyadingeka lapho ulisebenzisa kanye:

  • I-Erythromycin;
  • ngama-antimycotic agents;
  • imicu;
  • I-cyclosporine;
  • i-nicotinic acid.

Le mishanguzo iyakwazi ukukhulisa ukugcwala kwe-Atorvastatin egazini, ngenxa yokuthi kukhona ubungozi bemiphumela emibi.

Kuyadingeka futhi ukuqapha ngokucophelela inqubekela phambili yokwelashwa uma izidakamizwa ezinjengezengezwe eTorvacard:

  • Colestipol;
  • I-Cimetidine;
  • I-Ketoconazole;
  • izindlela zokuvimbela inzalo ngomlomo;
  • I-Digoxin.

Ukuqamba isu elifanele lokwelashwa, udokotela kumele azi ngayo yonke imishanguzo ethathwa yisiguli. Lokhu kuzomvumela ukuthi ahlolisise isithombe.

Ama-Analog

Phakathi kwemithi efanelekile ukufaka lesi sidakamizwa okukhulunywa ngaso izindlela zingabizwa:

  • I-Rovacor;
  • Atoris;
  • I-Liprimar;
  • UVasilip;
  • Pravastatin.

Ukusetshenziswa kwabo kufanele kuvunyelwane nodokotela. Ngakho-ke, uma kunesidingo sokukhetha ama-analogues ashibhile alo muthi, udinga ukuxhumana nochwepheshe.

Umbono wesineke

Ukubuyekezwa mayelana nomuthi iTorvakard kuyaphikisana impela - abaningi beza nomuthi, kepha iziguli eziningi zaphoqelelwa ukwenqaba ukuthatha lo muthi ngenxa yemiphumela emibi, okubuye kubuye kugcizelele isidingo sokubonisana nodokotela nokubheka ukusetshenziswa kwaso.

Sekuphele iminyaka eminingi ngisebenzisa iTorvacard. Inkomba ye-cholesterol yehle ngesigamu, imiphumela emibi ayenzekanga. Udokotela waphakamisa ukuthi ngizame elinye ikhambi, kodwa ngenqaba.

UMarina, oneminyaka engama-34

Ngaba nemiphumela emibi eminingi evela eTorvacard. Ukuqina kwekhanda njalo, isicanucanu, ukuthamba ebusuku. Wahlupheka amasonto amabili, wabe esecela udokotela ukuthi afake elinye leli khambi ngenye into.

UGennady, iminyaka engama-47

Angiwathandanga la maphilisi. Ekuqaleni yonke into yayihlelekile, kwathi ngemuva kwenyanga ingcindezi yaqala ukugxuma, ukuqwasha nokuqhamuka ekhanda kakhulu. Udokotela wathi izivivinyo zaba ngcono, kepha mina uqobo lwazizwa kabi. Kwakufanele ngenqabe.

U-Alina, oneminyaka engama-36

Sekuphele izinyanga eziyisithupha ngisebenzisa iTorvard futhi ngijabule kakhulu. I-cholesterol ijwayelekile, ushukela wehle kancane, ingcindezi yenziwa yajwayelekile. Angibonanga imiphumela emibi.

UDmitry, oneminyaka engama-52

Intengo yeTorvacard iyahluka ngokuya ngomthamo we-Atorvastatin. Kumathebhulethi angama-30 we-10 mg, udinga ukukhokha ama-ruble angama-250 ukuya kwangama-30. Ukuthenga iphakethe lamathebhulethi angama-90 (20 mg) kuzodinga ama-ruble ayi-950-1100. Amacwecwe anokuqukethwe okuphezulu kakhulu kwento esebenzayo (40 mg) abiza ama-ruble ayi-1270- 1400. Leli phakheji liqukethe ama-90 ama-pcs.

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