I-Insulin Protafan NM - inkampani yezidakamizwa eyi-antidiabetic uNovo Nordisk. Lokhu ukumiswa kokulimala kokufakelwa kombala omhlophe nge-precipitate emhlophe. Ngaphambi kokuphatha, umuthi kumele unyakaziswe. Umuthi wenzelwe ekwelashweni kwesifo sikashukela sohlobo 1 nohlobo 2. I-Protafan isho insulin ephakathi nendawo. Kutholakala kuma-cartridge ekhethekile ama-NovoPen 3 ml syringe pens kanye naku-10 ml vials. Kuwo wonke amazwe kukhona ukuthengwa kombuso kwezidakamizwa zesifo sikashukela, ngakhoke iProtafan NM ikhishwa esibhedlela mahhala.
Okuqukethwe yi-athikili
- 1 Umthamo kanye nendlela yokuphatha
- 1.1 I-Protafan NM ayivunyelwe ukusebenzisa:
- 2 Izakhiwo ze-Pharmacological
- Imiphumela emibi eyi-2.1
- Ama-Analog angama-Protafan
- Ukuxhumana nezinye izidakamizwa
- 5 Ungayigcina kanjani i-insulin?
- 6 izibuyekezo
Imithamo nendlela yokuphatha
I-Protafan iyisidakamizwa esisebenza phakathi, ngakho-ke singasetshenziswa ngokuhlukile futhi sihlanganiswe nezidakamizwa ezithatha isikhathi esifushane, ngokwesibonelo, i-Actrapid. Umthamo ukhethiwe ngamunye. Imfuneko yansuku zonke ye-insulin yehlukile kubo bonke abanesifo sikashukela. Imvamisa, kufanele isuke ku-0,3 iye ku-1,0 IU ngekhilogremu ngosuku. Ngokukhuluphala noma esikhathini sokuthomba, ukumelana ne-insulin kungaqhamuka, ngakho-ke isidingo sansuku zonke siyokhula. Ngokushintsha kwendlela yokuphila, izifo ze-gland yegilo, i-pituitary gland, isibindi, nezinso, umthamo weProtafan NM ulungiswa ngawodwana.
Umuthi uphathwa kuphela ngaphandle kokuzenzela. Akuhloselwe ukujova ukungena ngaphakathi!
I-Protafan NM ayivunyelwe ukusebenzisa:
- nge-hypoglycemia;
- ngamaphampu wokufaka (amaphampu);
- uma ibhodlela noma ikhareji lonakele;
- ngokuthuthukiswa kokungafani komzimba;
- uma usuku lokuphelelwa isikhathi seluphelelwe yisikhathi.
Izici ze-Pharmacological
Umphumela we-hypoglycemic wenzeka ngemuva kokuqhekeka kwe-insulin nokubopha kwayo ama-receptors amaseli emisipha namafutha. Izakhiwo eziyinhloko:
- kwehlisa ushukela wegazi;
- kuthuthukisa ukuthathwa koshukela emangqamuzaneni;
- kuthuthukisa i-lipogenesis;
- kuvimbela ukukhishwa koshukela esibindini.
Ngemuva kokuphathwa kwe-subcutaneous, ukugxila okukhulu kwe-Protafan insulin kubhekwa amahora angama-2-18. Ukuqala kwesenzo kungemva kwamahora ayi-1.5, umphumela omkhulu wenzeka ngemuva kwamahora angama-4 kuya kwayi-12, ubude besikhathi ngamahora angama-24. Ezifundweni zemitholampilo, bekungenakwenzeka ukukhomba i-carcinogenicity, i-genotoxicity kanye nemiphumela eyonakalisayo emisebenzini yokuzala, ngakho-ke i-Protafan ibhekwa njengesidakamizwa esivikelekile.
Imiphumela emibi
- I-Hypoglycemia ivame ukukhula.
- Ama-hives and ukulunywa, i-retinopathy yesifo sikashukela, i-edema, i-neuropathies yangaphakathi.
- Ukuphendula kwe-anaphylactic nokuphazamiseka kokuphikiswa kwamehlo akuvamile kakhulu.
Ama-Analog of Protafan
| Isihloko | Umkhiqizi |
| I-Insuman Bazal | ISanofi-Aventis Deutschland GmbH, eJalimane |
| Br-Insulmidi ChSP | I-Bryntsalov-A, eRussia |
| I-Humulin NPH | U-Eli Lilly, e-United States |
| I-Actrafan HM | INovo Nordisk A / O, eDenmark |
| I-Berlinsulin N Basal U-40 neBerisisulin N Basal pen | Berlin-Chemie AG, eJalimane |
| Humodar B | I-Indar Insulin CJSC, e-Ukraine |
| I-Biogulin NPH | Bioroba SA, eBrazil |
| Homofan | EPliva, eCroatia |
| I-Isofan Insulin World Cup | I-AI CN Galenika, Yugoslavia |
Ngezansi ividiyo ekhuluma ngezidakamizwa ezenziwa nge-isofan insulin:
Ngingathanda ukwenza ukuhlela okwami kuvidiyo - kuyenqatshelwe ukuphatha i-insulin isikhathi eside ngokuhlinzwa!
Ukuxhumana nezinye izidakamizwa
Imithi enciphisa isidingo se-insulin:
- Ama-inhibitors e-ACE (Captopril);
- izidakamizwa ze-hypoglycemic zomlomo;
- I-mao monoamine oxidase inhibitors (furazolidone);
- ama-salicylates nama-sulfonamides;
- ama-beta-blockers angakhethi (metoprolol);
- Ama-anabolic steroid
Izidakamizwa ezikhulisa isidingo se-insulin:
- i-glucocorticoids (i-prednisone);
- i-sympathomimetics;
- izindlela zokuvimbela inzalo ngomlomo;
- i-morphine, i-glucagon;
- abamelene ne-calcium;
- ama-thiazides;
- ama-hormone egilo.
Ungayigcina kanjani i-insulin?
Imiyalo ithi awukwazi ukukhulula umuthi. Gcina endaweni ebandayo emazingeni okushisa angama-2 kuye kwangama-8. Ibhodlela elivulekile noma i-cartridge akufanele ligcinwe esiqandisini endaweni emnyama amasonto angafika ku-6 emazingeni okushisa afinyelela kuma-30 degrees.
Ukubuyekezwa
Ububi obukhulu beProtafan nezimpawu zayo ukubakhona kwenani eliphakeme lomsebenzi amahora angama-4-6 ngemuva kokuphathwa. Ngenxa yalokhu, umuntu onesifo sikashukela kufanele ahlele indlela adla ngayo kusengaphambili. Uma ungadli phakathi nalesi sikhathi, i-hypoglycemia iyakhula. Ingasetshenziswa abesifazane abakhulelwe nezingane.
Isayensi ayimile, kukhona ama-insulin amasha angenantambo uLantus, Tujeo njalonjalo. Ngakho-ke, ngokuzayo wonke umuntu uzodluliselwa ezidakamizweni ezintsha ukuze anciphise ubungozi be-hypoglycemia.
