I-Diabeteson MV 60 mg: imiyalo yokusebenzisa, intengo, izibuyekezo

Ukwakheka nefomu lokukhululwa

I-Diabeteson MV ikhiqizwa ngohlobo lwezibhebhe ezine-notch kanye nombhalo "DIA" "60" kuzinhlangothi zombili. Into esebenzayo yi-gliklazid 60 mg. Izakhi ezisizayo: i-magnesium stearate - 1.6 mg, i-anlorous colloidal silicon diabetes - 5.04 mg, maltodextrin - 22 mg, hypromellose 100 cP - 160 mg.

Izinhlamvu "MV" egameni likaDiabeteson zichazwe njengokukhishwa okulungisiwe, i.e. kancane kancane.

Umkhiqizi: I-Les Laboratoires Serviceier, eFrance

Ukwenza kanjani uDiabeteson MV

I-Diabeteson ibhekisela kuma-sulfonylureas wesizukulwane sesi-2. Isebenza ama-pancreas nama-b-cell abhekene nokukhiqizwa kwe-insulin. Isebenza kahle uma amaseli esebenza ngandlela thile. Umuthi unqunywe ngemuva kokuhlaziywa kwe-c-peptide, uma umphumela ungaphansi kuka-0,26 mmol / L.

Ukukhishwa kwe-insulin lapho kuthathwa i-gliclazide kusondele kakhulu ngokomzimba ngangokunokwenzeka: inani eliphakeme lokukhuphuka libuyiselwa lapho kuphendula ukungena kwe-dextrose ukungena kwegazi kusuka kuma-carbohydrate, ukukhiqizwa kwe-hormone esigabeni 2 kuyathuthuka.

I-Pharmacokinetics

Ngemuva kokuphathwa ngomlomo, isifo sikashukela simunca ngokuphelele. Ukwanda kokuxakaniseka kwento esebenzayo egazini ihlala amahora angama-6 futhi kungagcinwa ezingeni elifinyelelwayo kuze kufike emahoreni ayi-12.

Ukuxhumana namaprotheni e-plasma afinyelela kuma-95%, umthamo wokusabalalisa ungama-30 l. Ukugcina ukugxilwa kwe-plasma okungapheli amahora angama-24, umuthi unele ukuthatha ithebhulethi eyi-1 isikhathi esisodwa ngosuku.

Ukuqhekeka kwento kwenziwa kulesibindi. Kukhishwe izinso: ama-metabolites athululiwe, <1% aphuma ngesimo sawo sokuqala. I-Diabeteson MV isuswa emzimbeni ngesigamu emahoreni ayi-12−20.

Izinkomba zokusetshenziswa

• I-Diabeteson MV (60 mg) inqunywe ngudokotela ngesifo sikashukela sohlobo II, lapho ukudla okwenzelwe ngokukhethekile kanye nokuzivocavoca komzimba kungasebenzi.
• Isetshenziselwa futhi ukuvikela izinkinga zesifo sikashukela: ukunciphisa ubungozi be-macrovascular (stroke, myocardial infarction) kanye nezinkinga ze-microvascular (retinopathy, nephropathy) ezigulini ezinesifo sikashukela sohlobo 2.

Contraindication

• Thayipha isifo sikashukela
• ukungabekezeleli i-gliclazide, i-sulfonylurea ne-sulfonamide, i-lactose;
• i-galactosemia, i-glucose-galactose malabsorption;
• ushukela wegazi ophakeme nemizimba ye-ketone;
• ngezindlela ezinzima zokulimala kwe-renal ne-hepatic, i-Diabeteson i-contraindication;
• ebuntwaneni nasebusheni
• isikhathi sokukhulelwa;
• ukuncelisa;
• Izimo zempilo yesifo sikashukela nekhohlo.

Ukukhulelwa nokuncelisa ibele

Ucwaningo olwenziwe kwabesifazane abasezikhundleni alwenziwe; akukho datha ngemiphumela ye-gliclazide enganeni engakazalwa. Ngesikhathi sokuhlolwa ezilwaneni zokuhlola, akukho siphazamiso ekuthuthukisweni kwe-embryonic kwaphawulwa.

Uma ukukhulelwa sekwenzekile ngenkathi kuthathwa i-Diabeteson MV, kuyakhanselwa bese kushintshwa ku-insulin. Okufanayo kuhamba ngokuhlela. Lokhu kuyadingeka ukunciphisa amathuba okukhulisa ukungazalwa kahle ezinganeni.

Sebenzisa ngesikhathi sokuncelisa

Akukho mininingwane efanelekile eqinisekisiwe ngokufakwa kweDiabeteson ebisini kanye nengozi engaba khona yokuthola isimo se-hypoglycemic kosana, kuyanqatshelwa ngesikhathi sokuqunjelwa. Lapho kungekho okunye okukhona nganoma yisiphi isizathu, adluliselwa ekunikezeni ukudla okwenziwe ngamawala.

Imiyalo yokusebenzisa

I-Diabeteson MV ivunyelwe ukuthathwa kuphela ngabantu abadala. Ukwemukelwa kwenziwa isikhathi esingu-1 ngosuku ngosuku ngokudla. Imithamo yansuku zonke isethwe ngudokotela, ubukhulu bayo bungafinyelela ku-120 mg. Ithebhulethi noma uhhafu walo ugezwa phansi ngengilazi yamanzi ahlanzekile. Musa ukuhlafuna futhi ugaye.

Uma weqa umthamo ongu-1, umthamo ophindwe kabili awemukelwa.

Umthamo wokuqala

Ekuqaleni kokwelashwa, kucishe kube yingxenye yethebhulethi, i.e. 30 mg Uma kunesidingo, umthamo we-Diabeteson MV kancane uyakhuphuka ufike kuma-60, 90 noma u-120 mg.

Umthamo omusha wesidakamizwa awunqunywa ngaphambi kwenyanga eyi-1 ngemuva kokunquma owedlule. Okuhlukile ukuthi abantu abanegazi likashukela abangaguquki ngemuva kwamaviki ama-2 ukusuka kudosi lokuqala. Ezigulini ezinjalo, umthamo wenyuka ngemuva kwezinsuku eziyi-14. Ezigulini ezineminyaka engaphezu kwengu-65, ukulungiswa akudingekile.

Ukwemukelwa ngemuva kwezinye izidakamizwa ze-antidiabetes

Imithamo yezidakamizwa ezidlule kanye nesikhathi sokuphuma kwazo ziyabhekwa. Ekuqaleni, umthamo ungama-30 mg, ulungiswa ngokuya nge-glucose esegazini.

Uma uDiabeteson MV eba obambele umuthi isikhathi sokuqothula, umthamo wokugcina umisiwe izinsuku ezingama-2-3. Umthamo wokuqala ubuye ngu-30 mg. Abantu abane-pathology yezinso etholakele abadingi ukulungiswa komthamo.

Iqembu lengozi:

1. Isimo se-Hypoglycemic ngenxa yokungondleki kahle.
2. Ukuntuleka kwe-pituitary and adrenal, ukuntuleka isikhathi eside kwama-hormone we-thyroid.
3. Yekani ukuthatha ama-corticosteroids ngemuva kokwelashwa isikhathi eside.
4. Isifo esikhulu se-artery coronary artery, ukubekwa kwamachibi e-cholesterol ezindongeni zemithambo ye-carotid artery.

Imiphumela emibi

Lapho uthatha isifo sikashukela ngokuhambisana nokudla okungajwayelekile, i-hypoglycemia ingahle ibe khona.

Izimpawu zakhe:

• ikhanda, isiyezi, ukuqonda kokulimala;
• umuzwa ongapheli wendlala;
• isicanucanu, ukuhlanza
• ubuthakathaka obujwayelekile, izandla eziqhaqhazelayo, iziqubu;
• ukungaphatheki kahle okungenasizathu, injabulo yenjabulo;
• ukuqwasha noma ukozela kakhulu;
• ukulahlekelwa ukwazi nge-coma engenzeka.

Ukuphendula okulandelayo okunyamalala ngemuva kokuthatha okumnandi nakho kungatholakala:

• Ukujuluka ngokweqile, isikhumba sinamathela lapho sithintwa.
• I-Hypertension, i-palpitations, i-arrhythmia.
• Ubuhlungu obukhali endaweni yesifuba ngenxa yokuntuleka kwegazi.

Eminye imiphumela engafuneki:

• Izimpawu ze-dyspeptic (Ubuhlungu besisu, isicanucanu, ukugabha, isifo sohudo noma ukuqunjelwa);
• ukungahambi kahle komzimba ngenkathi uthatha isifo sikashukela;
• ukwehla kwenani lama-leukocytes, ama-platelet, inani lama-granulocytes, okuhlushwa kwe-hemoglobin (izinguquko ziphinde ziphenduke);
• umsebenzi owengeziwe we-hepatic enzymes (AST, ALT, alkaline phosphatase), amacala aqukethe i-hepatitis;
• ukuphazamiseka kohlelo lokubonakalayo kungenzeka ekuqaleni kwesifo sikashukela.

Ukweqisa

Ngokweqile kwe-Diabetesone, isimo se-hypoglycemic singakhula. Uma ukwazi kungakukhubazeki futhi kunezimpawu ezinkulu, khona-ke kufanele uphuze ujusi noma itiye noshukela. Ukuze i-hypoglycemia ingaphindi, udinga ukwandisa inani lama-carbohydrate ekudleni noma ukunciphisa umthamo womuthi.

Ukulaliswa esibhedlela kuyadingeka lapho isimo esinamandla se-hypoglycemic sivele. Isixazululo sikashukela esingu-50 ml 40% sithunyelwa ngaphakathi kweziguli. Ngemuva kwalokho, ukuze kulondolozwe ukugxila kwe-glucose ngaphezulu kwe-1 g / l, i-10% dextrose idonswa.

Ukuxhumana neminye imithi

Izidakamizwa ezikhulisa umphumela we-gliclazide

I-ejenti ye-antifungal Miconazole ibhalwe ngemithi. Kwandisa ubungozi bokuthuthukisa isimo se-hypoglycemic, kuze kufike ku-coma.

Ukusetshenziswa kukaDiabeteson nomuthi ongeyona i-steroidal anti-inflammatory Phenylbutazone kufanele kuhlanganiswe ngokucophelela. Ngokusebenzisa okuhleliwe, kubambezela ukuqedwa kwesidakamizwa emzimbeni. Uma ukuthatha i-Diabeteson kudingekile futhi kungenakwenzeka ukuyibuyisela ngokuthile, kulungiswa umthamo we-gliclazide.

I-Ethyl yotshwala ikhulisa isimo se-hypoglycemic futhi ivimbele ukunxeshezelwa, okunomthelela ekuthuthukiseni ikoma. Ngalesi sizathu, kungakuhle ukuthi ungafaki utshwala nezidakamizwa eziqukethe i-ethanol.

Futhi, ukuthuthukiswa kwesimo se-hypoglycemic nokusetshenziswa okungalawulwa nesifo sikashukela kunomthelela kulokhu:

• IBisoprolol;
• I-Fluconazole;
• I-Captopril;
• I-Ranitidine;
• I-Moclobemide;
• I-Sulfadimethoxine;
• I-Phenylbutazone;
• I-Metformin.

Uhlu lukhombisa izibonelo ezithile kuphela, amanye amathuluzi aseqenjini elifanayo nalawo abhalwe ohlwini anomphumela ofanayo.

Izidakamizwa ezithoba isifo sikashukela

Musa ukuthatha uDanazole, njengoba inomphumela wesifo sikashukela. Uma ukwamukela kungeke kukhanselwe, kufanele kulungiswe i-gliclazide isikhathi sokwelashwa kanye nangemva kwayo.

Ukulawula ngokucophelela kudinga ukuhlanganiswa nama-antipsychotic kumithamo emikhulu, ngoba basiza ukunciphisa ukukhululeka kwama-hormone futhi bakhuphule ushukela. Ukukhethwa komthamo we-Diabeteson MV kwenziwa kokubili ngenkathi yokwelapha nangemva kokukhipha kwayo.

Ekwelashweni nge-glucocorticosteroids, ukugcwala kwe-glucose kukhuphuka nokwehla okungenzeka kokubekezelelwa kwe-carbohydrate.

Ama-agraists we-Intravenous β2-adrenergic akhulisa ukuqina kwe-glucose. Uma kunesidingo, isiguli sidluliselwa ku-insulin.

Inhlanganisela okungafanele ibukelwe

Ngesikhathi sokulashwa nge-warfarin, iDiabeteson ingandisa umphumela wayo. Lokhu kufanele kubhekwe ngale nhlanganisela bese kulungiswa umthamo we-anticoagulant. Ukulungiswa komthamo kokugcina kungadingeka.

Imiyalo ekhethekile

I-Hypoglycemia

Kungcono ukuthatha i-Diabeteson MV kuphela kubantu abadla ngokulinganisela futhi njalo ngaphandle kweqa ukudla okubalulekile - ibhulakufesi. Ama-carbohydrate ekudleni abaluleke kakhulu, ngoba ubungozi bokukhula kwesimo se-hypoglycemic bukhuphuka ngokuqondile ngokusetshenziswa kwabo okungajwayelekile, kanye nokudla okuphansi kwekhalori.

Izimpawu ze-Hypoglycemic zingaphindeka. Ngezimpawu ezinzima, noma ngabe kunokuthuthuka kwesikhashana ngemuva kokudla kwe-carbohydrate, ukunakekelwa okukhethekile kuyadingeka, kwesinye isikhathi kuze kufike esibhedlela.

Ukuvimbela lokhu kungenzeki, kufanele usondele ekukhetheni umthamo we-Diabeteson.

Amacala akhulisa ubungozi besimo se-hypoglycemic:

1. Ukungafuni nokuhluleka komuntu ukulandela imiyalelo kadokotela.
2. Ukudla okungenampilo, ukweqa ukudla, ukugadla kwendlala.
3. Ukusebenza okungabalulekile ngokomzimba ngenani elikhulu lama-carbohydrate aqediwe.
4. Ukwehluleka kwangempela
5. I-overdose ye-gliclazide.
6. Isifo se-yegilo.
7. Ukuthatha umuthi othile.

Ukwehluleka kwangempela nokwenziwa kwesibindi

Izici zezinto zishintsha ngenxa yokwehluleka kwe-hepatic kanye ne-renal ezinzima. Isimo se-hypoglycemic singandiswa isikhathi eside, ukwelashwa okuphuthumayo kuyadingeka.

Imininingwane Yesiguli

Kufanele uvivinye umzimba njalo futhi uqaphe ushukela wakho, unamathele kumenyu ekhethekile, futhi udle ngaphandle kweqa. Isiguli nezihlobo zakhe kufanele bazi nge-hypoglycemia, izibonakaliso zayo nezindlela zokuma.

Ukulawulwa kwe-glycemic okunganele

Lapho isiguli sinomkhuhlane, izifo ezithathelwanayo, ukungenelela okukhulu kokuhlinzwa kuyabekwa, ukulimala kutholakala, ukulawulwa kwe-glycemic kuthambile. Kwesinye isikhathi kuba nesidingo sokushintshela ku-insulin ngokuqedwa kweDiabeteson MV.

Ukuphikiswa kwemithi yesibili kungenzeka, okuvela lapho lesi sifo siqhubeka noma lapho impendulo yomzimba nomuthi incipha. Imvamisa, ukukhula kwayo kwenzeka ngemuva kokwelashwa isikhathi eside ngemithi yomlomo ye-hypoglycemic. Ukuqinisekisa ukumelana kwesibili, i-endocrinologist ihlola ukunemba kwemithamo ekhethiwe kanye nokuhambisana kwesiguli ekudleni okunqunyelwe.

Ithonya kwikhono lokushayela izimoto nezinqubo

Ngesikhathi somsebenzi ngenkathi ushayela noma yimuphi umsebenzi odinga ukuthathwa izinqumo okusheshayo kombani, ukunakekelwa okuthile kufanele kuthathwe.

Analogs of Diabeteson MV

Yini engavalwa?

I-Diabeteson MV ingathathelwa indawo kanye nezinye izidakamizwa ngomthamo ofanayo nesithako esisebenzayo. Kepha kukhona into efana ne-bioavailability - inani lezinto ezifinyelela umgomo, i.e. ikhono lomuthi ukuthi ligxile. Kwamanye ama-analogues asezingeni eliphansi, aphansi, okusho ukuthi ukwelashwa kuzobe kungasebenzi, ngoba ngenxa yalokho, umthamo kungenzeka ungalungile. Lokhu kungenxa yekhwalithi elibi lempahla yokusetshenziswa, izinto ezisizayo, ezingavumeli ukuthi into esebenzayo ikhishwe ngokuphelele.

Ukugwema inkathazo, konke ukufaka esikhundleni kwenziwa kangcono ngemuva kokubonana nodokotela wakho.

Maninil, Metformin noma Diabeteson - okungcono?

Ukuqhathanisa ukuthi yikuphi okungcono, kufanelekile ukubheka izinhlangothi ezingezinhle zemithi, ngoba bonke babekelwe isifo esifanayo. Imininingwane yesidakamizwa i-Diabeteson MV inikezwe ngenhla, ngakho-ke, iManinil neMetformin zizoqhubeka nokubhekwa.

IManinil neMetformin bangamaqembu ehlukene ekhemisi, ngakho-ke umgomo wesenzo uhlukile kubo. Futhi ngayinye inezinzuzo zayo ezizodingeka emaqenjini athile eziguli.

Izici ezinhle:

Ngokuvama kokuphatha: I-Diabeteson MV ithathwa kanye ngosuku, iMetformin - izikhathi ezi-2-3, iManinil - izikhathi ezi-2-4.

Inani lentengo emakhemisi

Izindleko ze-Diabeteson MV 60 mg ziyahlukahluka kusuka kuma-ruble angama-260. kufika ku-380 rub. iphakethe ngalinye lamathebulethi angama-30.

Ukubuyekezwa kwesifo sikashukela

Catherine. Muva nje, udokotela unginqumele uDiabeteson MV kimi, ngithatha u-30 mg ngeMetformin (2000 mg ngosuku). Ushukela wehle ukusuka ku-8 mmol / L kuya ku-5. Umphumela wanelisekile, ayikho imiphumela emibi, i-hypoglycemia nayo.

UValentine Sekuphele unyaka ngiphuza isifo sikashukela, ushukela uvamile. Ngikudleni, ngiyahamba kusihlwa. Kwakunjalo ukuthi ngikhohlwe ukudla ngemuva kokudla lesi sidakamizwa, kwavela ukuthuthumela emzimbeni, ngaqonda ukuthi kwakuyi-hypoglycemia. Ngidle okumnandi ngemuva kwemizuzu eyi-10, ngizwe kahle. Ngemuva kwalesi sigameko ngidla njalo.