I-Rosinsulin P iyi-insulin yesimanje yokwelapha isifo sohlobo 1 nohlobo 2 sikashukela sokumelana nemithi yokwehlisa ushukela ngomlomo.
Igama Lezwe elingafanele
I-Soluble insulin (ubunjiniyela bezakhi zofuzo zomuntu)
I-Rosinsulin P iyi-insulin yesimanje yokwelapha isifo sohlobo 1 nohlobo 2 sikashukela sokumelana nemithi yokwehlisa ushukela ngomlomo.
I-ATX
A10AB01. Kubhekiselwa ezidakamizweni ezingasebenza ezifushane ze-hypoglycemic.
Khipha amafomu nokwakheka
Itholakala njengomjovo. Ku-1 ml yesisombululo iphinda i-insulin yabantu - 100 IU. Kubukeka njengoketshezi olusobala, amafu athile avumelekile.
Isenzo se-Pharmacological
Kuyi-analogue ye-insulin yabantu, etholakala kusetshenziswa i-deoxyribonucleic acid eyenziwe modified. Le insulin ixhumana nama-receptors e-membrane ye-cytoplasm futhi yakha indawo ezinzile. Ivuselela izinqubo ze-intracellular zokwakheka kwe-hexokinase, i-pyruvate kinase, synthetase ye-glycogen, njll.
I-insulin yehlisa inani loshukela ngenxa yokuncipha kokuthuthwa ngaphakathi kwamangqamuzana, ithuthukisa ukumuncwa kwayo. Isiza ukuqinisa inqubo yokwakheka kwe-glycogen futhi yehlise ukuqina kokuqamba kweglue esibindini.
Isikhathi sokusebenza salo muthi singenxa yobukhulu bokufakwa kwayo. Iphrofayili yesenzo iyahlukahluka kubantu abahlukile, kucatshangelwa uhlobo lomzimba nezinye izici.
Isenzo siqala isigamu sehora ngemuva komjovo, umphumela wethanga - ngemuva kwamahora angama-2-4. Isikhathi sokusebenza sisonke sifinyelela emahoreni angama-8.
I-Pharmacokinetics
Izinga lokumunca kanye nokuqala kwesenzo kuncike kwindlela yokusetha umjovo. Ukusatshalaliswa kwezakhi kwenzeka ngokungalingani ezicutshini. Umuthi awungeni isithintelo se-placental kanye nobisi lwebele, ukuze lufakwe kubantu besifazane abakhulelwe nababambayo.
I-insulin yehlisa inani loshukela ngenxa yokuncipha kokuthuthwa ngaphakathi kwamangqamuzana, ithuthukisa ukumuncwa kwayo.
It is metabolized in the kwesibindi yi-enzyme insulinase. Ukuqedwa kwesigamu sempilo sekuyimizuzu embalwa.
Izinkomba zokusetshenziswa
Kuboniswa ukwelashwa kwesifo sikashukela i-mellitus kanye nezimo ezixakile zihambisana nokungasebenzi kahle kwe-carbohydrate metabolism, ikakhulukazi, i-hyperglycemic coma.
Contraindication
Ihlangene nokuzwela okuphezulu kwe-insulin, hypoglycemia.
Ngokunakekela
Lolu hlobo lwe-insulin lubekwa ngokuqapha uma isiguli sithambekele ekuphenduleni kwe-hypoglycemic. Okufanayo kuyenzeka kwisifo se-yegilo.
Ungayithatha kanjani iRosinsulin P?
Isixazululo sale insulin sihloselwe ukujova i-subcutaneous injection, intramuscular and intravenous injection.
Ngoshukela
Umthamo nendlela yokusetha umjovo kunqunywa yi-endocrinologist ngokuqinile ngamunye. Isinkomba esiyinhloko lapho kuthathwa khona leli dosi yizinga le-glycemia yegazi. Nge-1 kg yesisindo sesineke, udinga ukungena kusuka ku-0,5 kuya ku-1 IU ye-insulin usuku lonke.
Kwethulwa uhhafu wehora ngaphambi kokudla okuyisisekelo noma isidlo se-carbohydrate. Izinga lokushisa lesisombululo lingamazinga okushisa egumbini.
Ngokwethulwa kwe-insulin eyodwa kuphela, imvamisa yokulimala imikho kathathu ngosuku. Uma kunesidingo, umjovo ufakwa izikhathi eziyisithupha ngosuku. Uma umthamo udlula i-0.6 IU, khona-ke ngesikhathi esisodwa udinga ukwenza imijovo emi-2 ezingxenyeni ezihlukene zomzimba. Umjovo wenziwa esiswini, ethangeni, enkalweni, endaweni yamahlombe.
Ngaphambi kokusebenzisa ipeni lesirinji, udinga ukufunda imiyalo.
Ngaphambi kokusebenzisa ipeni lesirinji, udinga ukufunda imiyalo. Ukusetshenziswa kwepeni lesirinji kudinga imisebenzi elandelayo:
- donsa cap bese ususa ifilimu kwinaliti;
- isikebhe ekhabetheni;
- khipha umoya ngenaliti (ukwenza lokhu, faka amayunithi ayi-8, ubambe isirinji ngokuqondile, udwebe ngaphakathi bese wehlisa kancane kancane amayunithi ama-2 kuze kube yilapho sekuvela umuthi ekugcineni kwenaliti);
- jikisa okhethiwe kancane kancane kuze kube yilapho kusetshenziswa umthamo owufunayo;
- faka inaliti;
- cindezela inkinobho yokuvala bese uyibamba kuze kube yilapho umugqa okhethiweyo ubuyela esimweni sawo sokuqala;
- bamba inalithi eminye imizuzwana eyi-10 uyisuse.
Imiphumela emibi
Umuthi ungadala imiphumela emibi, eyingozi kakhulu okuyi-hypoglycemic coma. Umthamo ongalungile wesifo sikashukela sohlobo 1 uholela ku-hyperglycemia. Ukhula kancane kancane. Ukubonakaliswa kwayo kungoma, isicanucanu, isiyezi, ukubukeka kwephunga elingemnandi le-acetone.
Engxenyeni yezitho zombono
Akuvamile ukudala ukonakala okubonakalayo ngendlela yombono ophindwe kabili noma izinto ezifiphele. Ekuqaleni kokwelashwa, ukwephulwa okwesikhashana kokuphikiswa kwamehlo kungenzeka.
Uhlelo lwe-Endocrine
I-Hypoglycemia, ehambisana nokufakelwa isikhumba, ukukhuphuka kwamakhaza, ukujuluka okubandayo, ukuzamazama komhlaba, ukukhulisa isifiso sokudla nokuholelekweni.
Allergies
Ukuvela kwe-allergic akuvamile kwenzeka ngesimo sokuqhuma nokushwabana kwesikhumba kanye ne-edema, okuvame kakhulu ukuba i-urticaria. Ezimweni ezingavamile kakhulu, ukwethuka kwe-anaphylactic kungahle kube khona.
Umthelela ekhonweni lokulawula izindlela
Ngoba Njengoba idivaysi yezokwelapha ingadala ukungasebenzi kahle kwengqondo, i-hypoglycemia, ukunakekelwa okukhethekile kufanele kuthathwe ngenkathi ushayela futhi usebenza ngemishini.
Imiyalo ekhethekile
Isixazululo akufanele sisetshenziswe uma kuye kwaba namafu noma senziwe iqhwa. Ngokuphikisana nesizinda sokwelashwa, izinkomba ze-glucose kufanele zigadwe ngaso sonke isikhathi. Umthamo wezidakamizwa unconyelwa ukuthi ulungiswe ukuthola izifo, i-pathologies ye-gland yegland, isifo sika-Addison, isifo sikashukela kubantu abaneminyaka engaphezu kwengama-65 ubudala. Izici ezikhuthaza isimo se-hypoglycemic yile:
- ukuguqulwa kwe-insulin;
- ukweqa ukudla;
- isifo sohudo noma ukugabha;
- ukukhuphuka komzimba;
- hypofunction ye-adrenal cortex;
- isifo sezinso nesibindi;
- ukuguqulwa kwesayithi lomjovo.
Umuthi wehlisa ukubekezelela komzimba kwi-ethanol.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Akunemikhawulo ekusetshenzisweni kwalo muthi ngesikhathi sokukhulelwa. Le insulin efushane ayiyona ingozi kumntwana okhulayo. Ngesikhathi sokubeletha, umthamo uyancishiswa, kepha ngemuva kokuzalwa kwengane, umthamo wangaphambilini walesi sidakamizwa uqalwa kabusha.
Ukwelashwa kukamama ongumhlengikazi kuphephile enganeni.
Akunemikhawulo ekusetshenzisweni kwalo muthi ngesikhathi sokukhulelwa.
Ukuyalela izingane iRosinsulin P
Ukunquma i-insulin ezinganeni kwenziwa kuphela ngemuva kokunconywa ngudokotela.
Sebenzisa ebudaleni
Kwesinye isikhathi kuyadingeka ukulungisa umthamo walomenzeli.
Isicelo sokusebenza kokulimala kwezinso
Ukuphazamiseka okukhulu kudinga ukulungiswa kwamthamo.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukwehliswa komthamo kuyadingeka ezifweni ezinamandla zesibindi.
Ukweqisa
Nge-overdose, iziguli zakha i-hypoglycemia. Izinga layo eliphansi liqedwa yisiguli ngokwaso. Ukuze wenze lokhu, yidla ukudla okunotha okune-carbohydrate. Ukumisa i-hypoglycemia ngesikhathi, isiguli kudingeka ngaso sonke isikhathi sibe nemikhiqizo equkethe ushukela.
Ezimweni ezimbi kakhulu, isiguli siphelelwa amandla, esibhedlela, i-dextrose ne-glucagon kuyabhalwa iv. Ngemuva kokuthi ukwazi komuntu kubuyiselwe, kufanele adle amaswidi. Lokhu kuyadingeka ukuvimbela ukubuyela emuva.
Ukubhema kusiza ukukhuphula ushukela.
Ukuxhumana nezinye izidakamizwa
Le mishanguzo ithuthukisa umphumela we-hypoglycemic:
- Bromocriptine ne-Octreotide;
- imithi ye-sulfonamide;
- ama-anabolics;
- imishanguzo ye-tetracycline;
- I-Ketoconazole;
- Mebendazole;
- I-Pyroxine;
- yonke imithi equkethe i-ethanol.
Yehlisa umphumela we-hypoglycemic:
- izindlela zokuvimbela inzalo ngomlomo;
- ezinye izinhlobo zokugaya;
- IHeparin;
- Clonidine;
- Phenytoin.
Ukubhema kusiza ukukhuphula ushukela.
Ukuhambisana notshwala
Ukuphuza utshwala kukhulisa ubungozi be-hypoglycemia.
Ama-Analog
Analogues of Rosinsulin P yile:
- I-Actrapid NM;
- I-Biosulin P;
- IGansulin P;
- IGensulin P;
- I-Insuran P;
- Humulin R.
Umehluko phakathi kweRosinsulin neRosinsulin P
Lo muthi uluhlobo lweRosinsulin. URosinsulin M noC bayatholakala.
Izimo zeholide zeRosinsulin R kusuka ekhemisi
Lesi sidakamizwa sikhishwa ekhemisi kuphela ngemuva kokwethula incwadi yezokwelapha - incwadi kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Cha.
Intengo yeRosinsulin P
Izindleko zepeni yesirinji yale insulin (3 ml) yisilinganiso sama-ruble ayi-990.
Izimo zokugcina zomuthi
Indawo enhle yokugcina le insulin esiqandisini. Gwema umuthi obandayo. Akufanele isetshenziswe ngemuva kokubanda. Ibhodlela eliphrintiwe ligcinwa ekushiseni kwegumbi isikhathi esingaphezu kwamaviki ama-4.
Isikhathi sokuphelelwa yisikhathi
Ilungele ukusetshenziswa kungakapheli iminyaka emithathu kusukela ngosuku lokukhiqizwa.
Umkhiqizi uRosinsulin P
Kwenziwa kwi-LLC Medsintez, eRussia.
Ukubuyekezwa mayelana neRosinsulin P
Odokotela
U-Irina, oneminyaka engama-50 ubudala, i-endocrinologist, eMoscow: "Le insulin efushane ephumelelayo, ebekelwe iziguli ezinesifo sikashukela sohlobo loku-1 njengesengezo kwezinye izinhlobo ze-insulin. Zinomphumela omuhle ngaphambi kokudla. Ezigulini ezinesifo sikashukela sohlobo 2, ngibuye nginikeze i-insulin njengoba okungeziwe ekusebenziseni izidakamizwa ukwehlisa ushukela wegazi. Ngazo zonke izincomo, imiphumela emibi ayithuthuki. "
U-Igor, oneminyaka engama-42 ubudala, i-endocrinologist, uPenza: "Ukufakwa kweRosinsulin R sekuzibonakalisile ekwelashweni kwezinhlobo ezahlukahlukene zesifo sikashukela 1. Iziguli zikubekezelela kahle lokhu kwelashwa, futhi ngokudla cishe azinayo i-hypoglycemia."
Iziguli
U-Olga, oneminyaka engama-45, uRostov-on-Don: "Le insulin, esiza njalo ukuqapha inkomba ye-glucose ebangeni elijwayelekile. Ngayijova isigamu sehora ngaphambi kokudla, ngemuva kwalo angizizwa ngicekeceka. Isimo sami sempilo siyenelisa."
UPavel, oneminyaka engama-60, eMoscow: "Bengihlala ngisebenzisa i-insulin, ebangela ukuthi ngiphelelwe ikhanda futhi kungaboni kahle. Lapho ngiyifaka esikhundleni seRosinsulin P, isimo sami sempilo sathuthuka kakhulu nokuchama ebusuku ngancipha. Ngabona ukuthuthuka okuncane kombono."
U-Elena, oneminyaka engama-55, uMurom: "Ekuqaleni kokwelashwa kwe-insulin, ngaphindeka kabili emehlweni ami futhi ngaba nekhanda. Amaviki amabili kamuva isimo sami saba ngcono futhi zonke izimpawu zokushintshwa kwe-insulin zangisinda. Ngawujove amahlandla amathathu ngosuku, kuyaqabukela lapho kudingeka ukwanda komthamo "
