I-Lozap ne-Lozap Plus: yikuphi okungcono?

I-Lozap ne-Lozap Plus izidakamizwa ze-antihypertensive ezikhiqizwe eSlovakia. Ukwazi ukunciphisa umfutho wegazi kanye nengcindezi ekujikelezeni kwe-pulmonary. Ngaphezu kwalokho, banciphisa umthwalo osenhliziyweni futhi babe nomphumela wokulinganisa wokulinganisa.

Isimilo se-Lozap

Umuthi, okuyi-blocker ye-angiotensin receptors, uyatholakala ngohlobo lwamacwecwe amhlophe we-biconvex emhlophe afakwe i-sheath yefilimu, ngalinye lawo liqukethe into esetshenziswayo ye-potassium losartan ekuqoqweni kwe:

• 12,5 mg;
• 50 mg;
• 100 mg

ILoapap neLozap Plus ziyakwazi ukunciphisa umfutho wegazi kanye nengcindezi ekujikelezeni kwe-pulmonary.

Umuthi uthengiswa ngamakhadibhodi amaphakethe angama-30, 60 noma angama-90.

IPotassium losartan, isakhi esisebenzayo seLozap, ikhipha imiphumela elandelayo emzimbeni:

• ngokukhetha vimba umphumela we-angiotensin II;
• khuphula umsebenzi we-renin;
• inhibit aldosterone, ngenxa yalokho ukulahleka kwe-potassium okubangelwa ukuthatha i-diuretic kuncishiswa;
• shintsha okuqukethwe kwe-urea ku-plasma.

Ezigulini ezinomfutho we-arterial hypertension, ongasindwa yisifo sikashukela i-mellitus, ukwelashwa okunomuthi kunganciphisa ukubonakaliswa kwe-proteinuria.

Iziguli ezinokwehluleka kwenhliziyo okungapheliyo ziboniswa ukuphatha umuthi we-prophylactic.

Iziguli ezinokwehluleka kwenhliziyo okungapheli zikhonjiswa indlela yokuvimbela:

• ukukhulisa ukubekezelela ukuzivocavoca;
• vimbela i-myocardial hypertrophy.

Izinkomba zokusetshenziswa kwe-Lozap yile mibandela elandelayo:

1. Umfutho wegazi ophezulu we-Arterial.
2. Ukwehluleka kwenhliziyo okungapheli.
3. Isidingo sokunciphisa ubungozi besifo senhliziyo.

Imithamo kufanele ilungiswe phansi lapho:

• izifo zesibindi;
• ukomisa;
• hemodialysis;
• Isiguli sineminyaka engaphezu kwama-75 ubudala.

Umthamo kufanele ushintshwe ubheke ezansi ezifweni zesibindi.

Umthamo kufanele ulungiswe phansi lapho isiguli sineminyaka engaphezu kwama-75 ubudala.

Umuthi uphambaniswe nabesifazane abakhulelwe.

Umuthi uphambaniswe nabesifazane abambisayo.

Lesi sidakamizwa sifakwa kubantu abangaphansi kweminyaka engu-18 ubudala.

Umuthi lo uphethwe ngemishanguzo kwabesifazane abakhulelwe nababolekayo, kanye nabantu abangaphansi kweminyaka engu-18 ubudala. Akunconyelwe ukuyithatha futhi nangobunwele obukhulayo bezitho ezikhona noma ezisizayo.

Lapho unquma, ukunakekelwa kufanele kuthathwe uma isiguli sikhombe:

• ukwehluleka kwenhliziyo;
• Isifo senhliziyo se-Ischemic;
• izifo ze-cerebrovascular;
• i-stenosis yemithambo ye-renal, noma i-aortic ne-mitral valve;
• ukwephulwa kwemali esele ye-electrolyte;
• umlando we-angioedema.

Ukungezwani komzimba kungenye yemiphumela emibi yokuphuza umuthi.

Ukuthatha i-potasium ye-losartan kungadala ukusabela okuningi okungekuhle. Phakathi kwazo kukhona:

• i-anemia kanye nokunye ukonakala kwezinhlelo zokujikeleza nokujikeleza kwama-lymphatic;
• ukubonakaliswa komzimba;
• gout
• i-anorexia;
• ukuqwasha noma ukuphazamiseka kokulala;
• ukukhathazeka nokunye ukuphazamiseka kwengqondo;
• ikhanda kanye nezinye izibonakaliso zokuphazamiseka kwesistimu yezinzwa;
• kwehlise i-acuity ebonakalayo, i-conjunctivitis;
• i-angina pectoris, ukuphazamiseka kwesigqi senhliziyo, ukushaya kwenhliziyo, isifo sohlangothi nokunye ukuphazamiseka kohlelo lwethambo;
• ukukhwehlela, ekhaleni;
• Ubuhlungu besisu, isicanucanu, isifo sohudo nokunye ukushuba kwesisu;
• i-myalgia;
• ukungasebenzi kahle kwesibindi kanye / noma ukusebenza kwezinso;
• ukuvuvukala
• i-asthenia, isifo sokukhathala okungamahlalakhona.

Izici zeLoapap Plus

Ukulungiselela okuhlanganisiwe, kukhiqizwe ngendlela yamathebulethi amafilimu aphuziwe aphelele, abe nengozi yokuhlukanisa ezinhlangothini zombili. Siqukethe izinto ezi-2 ezisebenzayo:

• potasium angiotensin II receptor antagonist losartan - 50 mg;
• diuretic hydrochlorothiazide - 12.5 mg.

I-Lozap Plus ilungiselelo elihlanganisiwe elikhiqizwe ngohlobo lwamathebulethi amafilimu aphuzi aphuzi anomngcele wokuhlukanisa ezinhlangothini zombili.

Amabhola aqukethe amaphilisi ayi-10 noma ayi-15 afakwa emabhokisini amakhadibhodi e-1, 2, 3, 4, 6, noma izingcezu eziyi-9.

Umphumela wemithi ye-hydrochlorothiazide ukwanda:

• ukukhiqizwa kwe-aldosterone;
• ukugxila kwe-plasma kwe-angiotensin II;
• umsebenzi wokuhlaziya kabusha.

Ngaphezu kwalokho, ukuphatha kwayo kunciphisa inani leplasma yegazi kanye nenani le-potassium kulo.

Ukudonswa okuhlanganisiwe kwalesi sakhi nge-potassium losartan kunikeza:

• umphumela we-synergistic, ngenxa yokuthi kutholwa umphumela othile ophikisayo we-hypotensive;
• ukwenza buthaka kwe-hyperuricemia kuqalwe yi-diuretic.

Okubalulekile iqiniso lokuthi ukwelashwa ngalo muthi akubangeli ushintsho ekuweni kwenhliziyo. Umuthi ukhonjiswa ukusetshenziselwa umfutho wegazi ophakeme, odinga ukwelashwa okuhlanganiswa. Ngaphezu kwalokho, ukuphatha kwayo kunciphisa ingozi yokuqhamuka nezifo zenhliziyo uma kwenzeka kuba nomfutho we-arterial hypertrophy kanye ne-hypertrophy yesibeletho sobunxele.

I-Lozap Plus ayikhonjiswa nge-gout.

Umthamo wokuqala wesidakamizwa 1 ithebhulethi ngosuku. Uma kunesidingo, singaphindwa kabili, ngenkathi ukwamukela kusenziwa kanye. Umthamo wansuku zonke kufanele ushintshwe lapho kukhona uchungechunge olufanayo lwezinkomba nomuthi owodwa we-Lozap.

Umuthi awunqunyelwe ukuthi:

• i-hyper- noma i-hypokalemia, i-hyponatremia;
• izifo ezinzima zezinso, isibindi, noma ipheshana lokuphefumula;
• i-gout noma i-hyperuricemia;
• i-anuria
• ukukhulelwa, ukukhulelwa, kanye nesikhathi sokuhlela sokukhulelwa;
• hypersensitivity kuzakhi zomuthi noma ze-sulfonamide.

Kufanele isetshenziswe ngokuqapha ezimeni ezifanayo ne-Lozap monotherapy, futhi naku:

• i-hypomagnesemia;
• izifo ezithinta izicubu;
• isifo sikashukela mellitus;
• i-myopia;
• isifuba somoya;

Imiphumela emibi yesidakamizwa ehambisana nokuphathwa ngokuhlanganyela kwe-losartan ene-hydrochlorothiazide ayikhonjwa. Yonke imiphumela emibi eyenzeka nalokhu kwelashwa ibangelwa isenzo sento ngayinye ngayinye ngokwehlukile.

Ku-asthma ye-bronchial, umuthi kufanele usetshenziswe ngokuqapha.

Ngokungeziwe emiphumeleni emibi ebangelwa i-potassium losartan futhi kuyafana nemiphumela emibi eyenzeka lapho uthatha i-Lozap, i-Lozap Plus ingadala:

• i-vasculitis;
• isifo sokuphefumula sokuphefumula;
• i-jaundice ne-cholecystitis;
• iminyakazo.

Ukuqhathanisa kweLozap neLozap Plus

Ukufana

Izidakamizwa okukhulunywa ngazo zihlanganisa izici ezilandelayo:

• izinkomba zokusetshenziswa;
• ifomu lethebhulethi lokukhishwa komuthi;
• ukuba khona kwe-potassium losartan ekwakhiweni.

Uyini umehluko?

Isici esiyinhloko sokuhlukanisa umehluko ekubumbeni. I-Lozap iyisidakamizwa esisodwa, futhi iLoapap iy umuthi ohlangene oqukethe izinto ezi-2 ezisebenzayo.

Umehluko wesibili obalulekile iqiniso lokuthi iLozap inemithamo ehlukene, kuyilapho umuthi wokuhlanganisa utholakala ngokuhlukahluka oku-1 kuphela.

Yikuphi okushibhile?

Kungenzeka ukuthenga iphakethe lamathebulethi angama-30 ale mithi ngamanani alandelayo:

• 50 mg - ama-ruble angama-246;
• I-50 mg + 12,5 mg - ama-ruble angama-306.

Ekuqoqweni okufanayo kwe-losartan potassium, amalungiselelo aqukethe i-hydrochlorothiazide abiza kakhulu ngo-25%.

I-Lozap ibhekwa njengendlela ephephile yokunciphisa umfutho wegazi kushukela.

Yini engcono i-Lozap noma i-Lozap Plus?

Isinqumo sokuthi yimuphi umuthi ozoba ngcono ezigulini singenziwa kuphela ngudokotela ngemuva kokuthatha i-anamnesis nokwenza uhlolo. Ithuba le-Lozap Plus lizoba umphumela walo owaziwa ngokwelashwa. Inzuzo ye-Lozap elula yokukhetha umthamo. Ngaphezu kwalokho, isidakamizwa esisodwa sibangela ukusabela okumbalwa okumbalwa futhi kube nezimpikiswano ezimbalwa.

Ngoshukela

Ingxenye esebenzayo yeLozap Lozartan kumthamo ofinyelela ku-150 mg / ngosuku ayikuthinti ukuhlangana koshukela egazini. Inzuzo enkulu yalesi sidakamizwa kulabo abahlushwa isifo sikashukela sohlobo 2 amandla ayo okwehlisa ukumelana ne-insulin. Ngakho-ke, iLozap ibhekwa njengendlela ephephile yokunciphisa ingcindezi kulesi sifo.

I-Thiazide diuretics, efaka i-hydrochlorothiazide, inganyusa amazinga kashukela. Ezigulini ezinesifo sikashukela, izinto ezinjalo kufanele zinqunywe kumithamo emincane (ingabi ngaphezu kwama-25 mg / ngosuku). Ngaphezu kwalokho, udinga ukwazi ukuthi ngoshukela owandisiwe, ukuhlanganiswa kweLozap Plus nge-aliskiren akwamukeleki. Ngakho-ke, ngesifo esinjalo, lesi sidakamizwa kufanele sithathwe ngokuqapha.

Ukubuyekezwa kodokotela

USorokin VT, owelaphi, oneminyaka engama-32: "Nginikeza izidakamizwa zaleli qembu ukuthi zithole umfutho wegazi ophambili esigabeni sokuqala. Ngicabanga ukuthi le mishanguzo iphephile ngokwanele umzimba futhi inciphise nomfutho wegazi ngempumelelo. Ngifuna ukuqaphela ukuthi ngesigaba esibi sesi sifo imiphumela yale mishanguzo ngeke yanele usuku nolunye uhlobo lwesidakamizwa se-antihypertensive, njenge-beta-blockers, kufanele lusetshenziswe. "

UDorogina MN, udokotela wezifo zenhliziyo, oneminyaka engama-43: “Ngesikhathi enza lo mkhuba, wafika esiphethweni sokuthi iSlovak Lozap ibekezeleleka kangcono kunabalingani bayo baseRussia. Iziguli ezingaphezu kwe-90% zikuqaphelile ukucindezelwa kanye nokungatholakali kokuphikisana nakho.

Ukubuyekezwa kweziguli mayelana ne-Lozap ne-Lozap Plus

U-Egor, oneminyaka engama-53, eYekaterinburg: "Wathatha izidakamizwa zombili. Zinomphumela ofanayo kimi, awubonanga umehluko ngezinga lokuncishiswa kwengcindezi. Ngithanda uLozap ngenxa yezindleko zawo eziphansi."

U-Alevtina, oneminyaka engama-57, eMoscow: "Ngicabanga ukuthi lesi sidakamizwa sibuthakathaka kakhulu. Uma siphuzwa ekuseni, kusihlwa, ingcindezi iqala ukuvela futhi."