Umuthi i-Espa Lipon ubhekisele kuma-hepatoprotectors. Umuthi uvikela isibindi ethonyeni lezinto ezingezinhle, futhi ulawula ne-carbohydrate kanye ne-lipid metabolism.
Igama Lezwe elingafanele
I-Tioctic acid.
U-Espa-Lipon uvikela isibindi emiphumeleni yezinto ezingezinhle.
I-ATX
I-A16AX01.
Khipha amafomu nokwakheka
Amaphilisi
I-600 mg ye-alpha lipoic (thioctic) acid munye ngamunye. Izinto ezengeziwe:
- isitashi se-sodium carboxymethyl;
- i-cellulose powder;
- I-MCC;
- i-povidone;
- i-monohydrogenated lactose;
- isilika;
- i-magnesium stearate;
- Udayi ophuzi we-quinoline;
- I-E171;
- macrogol-6000;
- hypromellose.
Kwiphakethe lomuthi, amaphilisi angama-30.
Egcekeni lamaphilisi angama-30.
Gxila
I-25 mg ye-thioctic acid ku-1 ml yesisombululo. Isithako esingeziwe yi-liquid injectable (amanzi). Kumaphakethe ama-5 ampoules we-24 ml.
Isenzo se-Pharmacological
I-MP ine-hypoglycemic, detoxization, hepatoprotective kanye ne-hypocholesterolemic effect, ebamba iqhaza kulawulo lwe-metabolism. I-Thioctic acid iyi-antioxidant ephumelelayo ekhuthaza ukusebenza kwe-cholesterol metabolism futhi ithuthukise ukusebenza kwesibindi.
Isakhi esisebenzayo sifana namavithamini B. Umuthi ukhuphula izinga le-glycogen ezinhlakeni zesibindi, wehlise ukugcwala kwe-plasma ye-glucose futhi uthuthukise ukutholakala kwe-insulin ngamaseli.
Ngaphezu kwalokho, i-MP isusa amakhompiyutha anobuthi emzimbeni, ivikela amaseli wesibindi emiphumeleni yawo, ivikela umzimba ekudakweni ngosawoti wensimbi.
Umuthi ukhuphula izinga le-glycogen ezakhiweni zesibindi.
Umsebenzi we-neuroprotective wezidakamizwa ususelwa ekucindezelweni kwe-lipid oxidation ezakhiweni zemicu yezinzwa nokukhuthaza ukuthuthwa kwezifiso zezinzwa.
I-Pharmacokinetics
I-Alpha lipoic acid igxilwe emgodini wokugaya ukudla ngesikhathi esifushane. Ukudla kuthinta kabi le nqubo.
Isimoji sakhiwe ngokusebenzisa i-oxidation yamaketanga aseceleni nokuhlangana. Iyakhishwa ngesikhathi sokuchama. I-T1 / 2 kusuka ku-plasma yegazi - kusuka kumaminithi ayi-10 kuye kwangama-20.
Izinkomba zokusetshenziswa
- i-polyneuropathy yotshwala;
- isifo sikashukela se-polyneuropathy;
- i-hepatic pathologies (kufaka phakathi isimo esingamahlalakhona se-hepatitis kanye ne-hepatic cirrhosis;
- ukudakwa obukhulu / obungamahlalakhona (ubuthi ngesikhunta, usawoti wensimbi, njll.);
- ukululama ngemuva kokuhlinzwa (ukuhlinzwa).
Ngaphezu kwalokho, i-MP ikhombisa ukusebenza kahle kakhulu ekwelapheni nasekuvimbeleni izifo zemikhumbi ye-arterial.
Contraindication
Umyalo ukhombisa imikhawulo enjalo ekusetshenzisweni kwe-hepatoprotector:
- utshwala;
- I-GGM (i-galactose-glucose malabsorption);
- ukuntuleka kwe-lactase;
- iminyaka yezingane;
- ukungabekezelelani.
U-Espa-Lipon uphambene notshwala.
Ngokunakekela
- ukukhulelwa
- ukuncelisa;
- isifo sikashukela mellitus;
- ukungasebenzi kahle kwezinso kanye / noma ukungasebenzi kahle kwesibindi.
Ungayithatha kanjani i-Espa Lipon
Ukugxiliswa kufafazwe ngesisombululo se-isotonic sodium chloride ngaphambi kokusebenzisa.
Kwi-polyneuropathy enobunzima (i-alcoholic, i-diabetes) isetshenziswa isikhathi esingu-1 / usuku ngendlela ye-IV infusions ye-24 ml yesidakamizwa, encibilikisiwe ku-250 ml wesisombululo se-sodium chloride. Isikhathi sokwelashwa sisuka kumaviki amabili kuya kwayi-4. Isixazululo sokufakwa sisebenza ngaphakathi kwemizuzu engama-45-55. Izisombululo ezenziwe ngomumo zilungele ukusetshenziswa kungakapheli amahora angama-5.5-6 ngemuva kokwenza.
Ukwelashwa okusekelayo kubandakanya ukusetshenziswa kwe-MP yohlobo lwethebhulethi kwimithamo ye-400-600 mg / ngosuku. Isikhathi esincane sokwamukelwa izinyanga ezintathu. Amacwecwe kufanele adakwe isigamu sehora ngaphambi kokudla, agezwe ngamanzi, ngaphandle kokuhlafuna.
Amacwecwe kufanele adakwe isigamu sehora ngaphambi kokudla, agezwe ngamanzi, ngaphandle kokuhlafuna.
Uma kungenazinkomba ezithile, khona-ke isifo sesibindi kanye nokudakwa kuyalashwa ngemithamo yethebhulethi engu-1 ngosuku.
Ngoshukela
Abantu abanesifo sikashukela kufanele bathole i-MP ngokulungiswa kwamthamo ngamunye kwe-insulin. Ngaphezu kwalokho, iziguli ezikuleli qembu zidinga ukuqashwa njalo kwamazinga kashukela.
Imiphumela emibi
Kukhona ubungozi bokuphendula komzimba: i-anaphylaxis, i-urticaria, ukuquleka, ukuvuvukala, ukulunywa. Kukhona futhi amathuba okuba hypoglycemia, izimo dyspeptic.
Umthelela ekhonweni lokulawula izindlela
I-MP ayikuthinti ukunaka nokuphendula uma uyithatha.
Imiyalo ekhethekile
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Amathuba okusebenzisa i-hepatoprotector ukuthola i-lactation / ukukhulelwa kunqunywa uchwepheshe ozocabanga ngezinzuzo zowesifazane nezingozi empilweni yengane.
Ukuqokwa kwe-Espa Lipon yezingane
Ezezingane ayisebenzi.
Sebenzisa ebudaleni
Asikho isidingo sokulungiswa kwamthamo.
I-drug overdose ibonakaliswa ngokuhlanza.
Ukweqisa
Kwesinye isikhathi kuvezwa ngokuhlanza, isicanucanu kanye ne-migraine. Ukwelashwa kuyimpawu. I-Thioctic acid ayinayo i-antidote.
Ukuxhumana nezinye izidakamizwa
Ngokuhambisana ne-hypoglycemics, kukhuphuka umsebenzi we-hypoglycemic we-MP.
I-Thioctic acid ayihambelani nesixazululo sika-Ringer noshukela. Lokhu kungenxa yokuthi le nto yakha izinto eziyinkimbinkimbi ngokuxhumana nama-molecule woshukela.
Isithako esisebenzayo singanciphisa umsebenzi wokwelapha umdlavuza.
Ukuhambisana notshwala
Iziguli ezithola lo MP zixwayiswa ukuthi zigweme ukuphuza utshwala.
Ama-Analog
- I-Oktolipen;
- I-Berlition;
- I-Thiolipone;
- I-Lipoic acid;
- I-Thioctacid 600 t;
- Tiolepta;
- I-Tiogamm.
Izimo zeholide u-Espa Lipona ovela ekhemisi
Ngingakwazi ukuthenga ngaphandle kadokotela
Ngaphandle kwemithi kadokotela, umuthi ngeke usebenze.
Intengo ye-espa lipon
Ukugxila kubiza kusuka kuma-ruble angama-705. kwama-ampoules ayi-5, amaphilisi - kusuka kuma-ruble angama-590. ama-30 ama-PC.
Izimo zokugcina zomuthi
Ngomswakama olinganiselayo nokushisa kwegumbi. Vikela umswakama nelanga.
Isikhathi sokuphelelwa yisikhathi
Hhayi ngaphezulu kweminyaka engu-2. Isixazululo se-infusion esilungiselelwe sigcinwa isikhathi esingekho ngaphezu kwamahora ayi-6.
Umkhiqizi u-Espa Lipon
USiegfried Hamelin GmbH (Germany).
Ukubuyekezwa mayelana ne-Espa Lipon
Odokotela
UGrigory Velkov (owelaphi), Makhachkala
Ithuluzi elisebenzayo ekwelapheni i-polyneuropathy yotshwala ne-diabetes. Enye yezinzuzo ubukhona bezindlela ezingama-2 zemithamo, okungukuthi, ukwelashwa kuqala ngokungeniswa kwe-iv, futhi kuyaqhubeka nokuphathwa kwamathebulethi. Lokhu kuchaza ukuthambekela okuhle komzimba, futhi kunciphise namathuba wokuphendula okungathandeki. Ezinye iziguli zididekile ngezindleko zezidakamizwa, kodwa iningi leziguli zenelisekile ngomphumela wazo.
U-Angelina Shilohvostova (isazi sezinzwa), iLipetsk
Umuthi uvame ukusetshenziswa njengengxenye yokwelapha okuyinkimbinkimbi ezigulini zikashukela. Imithi ejwayelekile yenza sikwazi ukugwema izinkinga ezahlukahlukene, ikakhulukazi kusuka ohlelweni lwezinhliziyo. Umuthi unqunywe ngomuthi futhi kufanele uchazwe kuphela uchwepheshe. Ukwemukelwa okungagunyaziwe akwamukeleki, ikakhulukazi nge-infusions. Kuyinto elula futhi ukuthi ngemuva kwe-infusions, ungashintshela kancane kancane ekusebenziseni umuthi ngendlela yethebhulethi. Emiphumeleni emibi, isiyezi kanye nokuphazamiseka kokugaya ukudla kulula kakhulu ukubonwa.
Iziguli
USvetlana Stepenkina, oneminyaka engama-37, u-Ufa
Ngiqale ukuphuza la maphilisi nginconywa ngudokotela oyi-neurologist, lapho umthambo wami osesiswini sami “ujuthelana”. Ngaphezu kwalokho, muva nje usanda kuhlola umphumela wezidakamizwa lapho ebhekene nesisindo ngokweqile. Emavikini ama-4 ngemuva kokuqala kokwelashwa, isisindo sehlile ngamakhilogremu ayi-9, futhi akubanga khona ukungaphatheki kahle.
Ngifuna ukuxwayisa wonke umuntu ukuthi awukwazi ukusebenzisa la mapilisi ngaphandle kokuya kudokotela, uma kungenjalo kungavela izinkinga ezinkulu, ngoba i-thioctic acid ikhona emithini.
U-Yuri Sverdlov, oneminyaka engama-43, uKursk
Isibindi sami siqale ukulimala kakhulu. Ngenxa yokungajabuli, umuntu wayevame ukuthatha isikhathi emsebenzini. Ukuhlaselwa okukhulunywa ngakho ikakhulukazi kwakungemva kokudla okuminyene. Inkinga yangezelela ukuthi ngangihlanza izinhlayiya ze-bile. Udokotela wabeka le mijovo namaphilisi, engaqala ukuwaphuza ngemuva kokufunda inkambiso yokungena. Umuthi ubiza kakhulu, kepha ngesaba impilo yami futhi nginqume ukuthi bekungafanele ukuba wonge. Umphumela waba ukujabulisa, ngisho induna yanyamalala ebusweni, okwathi ngok kadokotela, ikhombisa ukuthuthuka kokusebenza kwesibindi.
