URamipril umuthi wokwelapha ukuphazamiseka okuningi ekusebenzeni komzimba. Umuthi ungadala imiphumela emibi, ngakho udokotela kuphela ongawunquma.
Igama
NgesiLatini, kuzwakala njengeRamiprilum. Igama lokuhweba lifana nelokwendabuko.
URamipril umuthi wokwelapha ukuphazamiseka okuningi ekusebenzeni komzimba.
I-ATX
C09AA05.
Khipha amafomu nokwakheka
Amaphilisi
Indlela eyinhloko yesidakamizwa ivezwa ezibhebheni. Ithebhulethi eyi-1 iqukethe u-10 mg wento esebenzayo yegama elifanayo.
Amafomu wokukhishwa angatholakali
Ngendlela yamaphilisi, awukwazi ukuwuthenga umkhiqizo.
Indlela eyinhloko yesidakamizwa ivezwa ezibhebheni.
Isenzo se-Pharmacological
Ithuluzi elingelama-inhibitors e-ACE. Ivuselela i-vasodilation, inyusa ukuphuma kwenhliziyo nokuzivocavoca kokuvivinya umzimba. Ngokulashwa, ukumelana kwemithambo kuyathuthuka.
Uma isiguli saba nokuhluleka kwenhliziyo okuhlala isikhathi eside nokwenzeka kwe-myocardial infaration, ukuphuza lo muthi kuzomsiza ukuthi anciphise amathuba wokufa ngokuzumayo.
Umuthi osebenzayo usiza ukuvikela ukufakelwa kwe-myocardial ezigulini ezihlushwa yizifo zamaseli noma isifo sikashukela. Yehlisa ukufa ngesikhathi sokuvuselelwa kabusha.
URamipril uvusa i-vasodilation.
Umphumela we-antihypertensive wesidakamizwa ungabhekwa amahora angama-1-2 ngemuva kokuthatha iphilisi. Umuthi uzosebenza okungenani ngosuku.
I-Pharmacokinetics
Ngokuphathwa ngomlomo, ukumunca kuzoba cishe ama-50-60%. Ukudla kuzokwehlisa ijubane, yize kungapikiswanga ukuphuza amaphilisi ngalesi sikhathi. Ukuhlushwa okuphezulu kunakho konke kubhalwe egazini ngemuva kwamahora angama-2-4 isiguli sithathe umuthi. I-Metabolism iya esibindini.
I-60% idonswa yizinso, wonke umuthi ukhishwa ngamathumbu, nangendlela yama-metabolites.
Izinkomba zokusetshenziswa
Udokotela uzonikeza lesi sidakamizwa lesi siguli uma kutholakala ukuthi unale mibandela elandelayo:
- isifo sikashukela nesingesoshukela;
- i-arterial hypertension;
- ukwehluleka kwenhliziyo okungapheli nomlando wesifo senhliziyo.
Umuthi futhi unqunyelwe kwiziguli ezinobungozi obukhulu bethambo nalabo abake babhekana ne-coronary artery bypass grafting and stroke.
Contraindication
Awukwazi ukuthatha lesi sidakamizwa uma isiguli sinokugula okuthile kwezempilo. Lokhu:
- ukuthikamezeka okuphezulu kwento esebenzayo namanye ama-inhibitors e-ACE;
- i-hyperaldosteronism eyinhloko;
- i-stenosis yomlomo we-arterial;
- hyperkalemia
Uma kwenzeka ukungasebenzi kahle kwe-renal kanye ne-hepatic, i-ejenti kufanele ichazwe ngokunakekelwa okwengeziwe.
Ungayithatha kanjani i-ramipril?
Ukwemukelwa kwamathebulethi kwenziwa ngaphakathi. Umthamo ekuqaleni kokwelashwa imi ngalendlela elandelayo: 1.25-2.5 mg izikhathi ezi-1-2 ngosuku (inani eliphelele lomuthi lingafinyelela ku-5 mg). Ngaphezu kwalokho, lo mgamo uyabonakala. Kunoma yisiphi isimo, udokotela kufanele aqinisekise ngokuqondile umthamo, phakathi nokwelashwa, angawulungisa. Lomthamo ngowabantu abadala.
Isiguli ngasinye kufanele sifunde imiyalo okufanele isetshenziswe ngaphambi kokuthatha amaphilisi. Ekubonisaneni, kuyadingeka ukuthi uxwayise udokotela ngezimpawu zomzimba ngamunye kanye ne-pathologies ekhona.
Ukwemukelwa kwamathebulethi kwenziwa ngaphakathi.
Uma kunesidingo, udokotela angakhulisa umthamo, kubandakanya nokwelashwa kokulungiswa, ngawodwana.
Kukuziphi izingcindezi?
Umuthi ukhonjiswa ukusetshenziselwa umfutho wegazi ophansi.
Ngoshukela
Lo muthi uvame ukubekelwa lokhu kugula okungathi sína. Umthamo ukhethwa ngudokotela ohambelayo ukuze ungalimazi kakhulu impilo yesiguli.
Imiphumela emibi
Umuthi, njengabanye abaningi, ungaholela ekwakhiweni kwemiphumela emibi.
Lo muthi uvame ukubekelwa isifo sikashukela.
Amapheshana wesisu
Isicanucanu, isifo sohudo, izimpawu zesisu, ukugabha, umlomo owomile, ubuhlungu besisu, i-gastroenteritis ne-pancreatitis kungenzeka.
Izitho zeHematopoietic
Isiguli singase siqale ukuhlushwa i-hypotension, ukuhluleka kwenhliziyo, ukufakwa kwe-myocardial, nobuhlungu ku-sternum.
Isistimu yezinzwa ephakathi
Isibonakaliso secala esivamile kakhulu isiyezi. Ngokungeziwe kukho, lokhu kuphazamiseka okulandelayo kungavela: ikhanda, ukuqaqeka, ukungaboni kahle ne-neuropathy.
Kusuka ohlelweni lomchamo
Kungenzeka ukwephulwa kokusebenza kwezinso, i-edema, ukungabi namandla ngokocansi emadodeni.
Engxenyeni yesistimu yezinzwa ephakathi, uphawu uphawu olujwayelekile kakhulu isiyezi.
Kusuka ohlelweni lokuphefumula
Iziguli zingahlushwa i-pharyngitis, i-laryngitis ne-bronchospasm. Ukukhwehlela okunamandla kungenzeka.
Allergies
Kukhona ithuba lokuhlakulela ukusabela kwe-angioedema kanye ne-anaphylactic.
Imiyalo ekhethekile
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukuqokwa ngesikhathi sokukhulelwa akunakwenzeka. Uma kuvela ukuthi owesifazane wakhulelwa ngenkathi elashwa ngalo muthi, kufanele ukhansele ukwelashwa okunjalo. Lokhu kungenxa yokuthi into esebenzayo ingaba nomphumela olimazayo kumbungu. Angase aqhamuke ne-hypoplasia yamaphaphu nesigaxa, ukonakala kwesikhumba, anciphise nengcindezi.
Ukuqokwa ngesikhathi sokukhulelwa akunakwenzeka.
Ukuncelisa amabele kufanele futhi kuyekwe ngenkathi umuthi usebenza emzimbeni wowesifazane.
Kunquma uRamipril ezinganeni
Ezinganeni nasentsheni eskhuleni esibalelwa eminyakeni eyi-18, umuthi awubekelwe kangako.
Ukweqisa
Ukudlula umthamo ophelele kungasongela ukwephulwa kokujikeleza kwe-cerebral, hypotension acterial hypterension ne-angioedema. Ezimweni ezinjalo, udinga ukunciphisa umthamo noma umise ngokuphelele umuthi wokwelapha. Isinqumo sokugcina kule ndaba singenziwa kuphela udokotela. Kuyadingeka ukwenza ukwelashwa okubonakalayo futhi unqume ama-antihistamines.
Ukuxhumana nezinye izidakamizwa
Umphumela we-antihypertensive wesidakamizwa ungancipha ngokuphathwa kanyekanye kwezidakamizwa ezingezona ze-antiidal. Ukuthuthukiswa komphumela kuzobukwa lapho kuthathwa ngama-profayili afanayo.
Umphumela we-antihypertensive wesidakamizwa ungancipha ngokuphathwa kanyekanye kwezidakamizwa ezingezona ze-antiidal.
Kukhona ukuthambekela kokuthuthukisa i-leukopenia uma isetshenziswa ndawonye nama-immunosuppressants kanye ne-cytostatics.
Abenzi
UHoechst AG (Germany). URamipril C3 ukhiqizwa yiNorth Star, eRussia.
Ungayishintsha kanjani i-ramipril?
Izimpawu zomuthi yiHartil, Corpril noTrace. Izifanekiso zomuthi kwakunguLisinopril, Bisoprolol (Akrikhin), Indapamide.
Izimo Zokhemisi Ramipril
Ungathenga umuthi kuphela ngomuthi kadokotela.
Ungathenga umuthi kuphela ngomuthi kadokotela.
Intengo
Izindleko zezimali eRussia azidluli kuma-ruble ayi-150, e-Ukraine - cishe ayi-120 hryvnia.
Izimo zokugcina zomuthi
Izinga lokushisa lokugcina lomuthi akufanele lidlule + 25 ° C.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emithathu
Ukubuyekezwa kukaRamipril
Iziguli eziye zelashwa ngalo muthi zishiya izibuyekezo ezinhle ngakho futhi zingakutusa ukwelashwa kubantu abanezinkinga ezifanayo.
U-Irina, oneminyaka engama-34 ubudala, uKrasnoyarsk: "Bengihlukumeza umzimba ngokweqile ngalesi sidakamizwa. Njengoba umuthi ubangela ukusabela okungekuhle futhi ukwelashwa okuhloswe ngakho ukuqeda ukuphazamiseka okukhulu ekusebenzeni komzimba, ukwelashwa kwenziwa esibhedlela ngaphansi kokuqashwa okuqinile kwezokwelapha. Izimpawu zalesi sifo ngokushesha zanyamalala futhi zaba lula ngemuva kwesikhashana nje ngemuva Ngibonga kakhulu kodokotela ngokunginikeza ikhambi elihle kakhulu. Ngingasincoma lesi sidakamizwa kuwo wonke umuntu, ngoba sisebenza kahle futhi ngokushesha, ngenxa yalokho Kujwayelekile. "
U-Igor, oneminyaka engama-45 ubudala, uNovosibirsk: "Yize kwenzeka ukuthi isifo esinzima selashwa, bekungafanele ngilale esibhedlela ngenkathi elashwa ngalo muthi. Kwakuyisikhathi esikahle. Lapho umuthi usuqaliwe, ngaba nentshisekelo ngezindleko zawo. Kwavela ukuthi waphansi. Ngaphandle kwalokhu, imiphumela azithathanga isikhathi eside ukulinda. Isimo sizinzile isonto ngemuva kokuqala kokwelashwa. Ngakho-ke, ngicabanga ukuthi umuthi usebenza ngempumelelo esigabeni sawo. Ngidinga ukwelulekwa kwezokwelashwa nokuqashwa ngesikhathi sokwelashwa, njengoba isiguli sihlangana naso ukusabela okungekuhle. "
