IZIMBANGELA KANYE NEZIMPAWU ZESIFO SIKASHUKELA SOHLOBO 2

Send

Uhlobo II sikashukela i-mellitus - isifo se-metabolic esibonakaliswa yi-hyperglycemia engapheli - ushukela weplasma ophakeme.

Isici esiyingqayizivele sesifo sikashukela sohlobo 2 ukuswela ukuncika ngokuqondile ekukhiqizweni kwe-insulin. I-hormone ingahle ihlanganiswe ngenani elihambisana nesimo esejwayelekile, kepha ukusebenzisana kwe-insulin nezinhlaka zamaselula kuyaphazamiseka, ngenxa yalokho into leyo ingagxilwanga.

Izici Ezicacisiwe Zesifo Sikashukela sohlobo 2

Lesi sifo sisuselwa esakhiweni se-pathological of izicubu esibizwa ngokuthi yi-insulin ukumelana.

Lesi simo singabangelwa ukungasebenzi kahle kwamanyikwe: ngemuva kokudla, lapho kuphakama ushukela we-plasma, ukukhiqizwa kwe-insulin akwenzeki. I-hormone iqala ukukhiqizwa emuva kwesikhathi, kepha ngaphandle kwalokhu, ukwehla kwamazinga kashukela akubonwa.

Ngenxa ye-hyperinsulinemia engapheli, ukuzwela kwama-receptors asodongeni lweseli futhi obhekene nokuqashelwa kwe-hormone kuyancishiswa. Noma i-receptor ne-insulin zihlangana, umphumela we-hormone kungenzeka ungabi yile: lesi simo ukumelana ne-insulin.

Ngenxa yokuguqulwa okunjalo kwe-pathological ku-hepatocytes (amayunithi wesakhiwo), ukwakheka kweglue kuyenziwa kusebenze, ngenxa yalesi sizathu ezigulini ezinesifo sikashukela sohlobo lwe-2 izinga lama-carbohydrate lenyuka ngisho nasesiswini esingenalutho nasezigabeni zokuqala zesifo.

Izimpawu nezimpawu zohlobo 2 sikashukela

I-glucose ephakeme ngokungapheli ibangela izimpawu ezibuhlungu:

I-glucose ubuthi bukhula, buthinta kabi amaseli okusebenza kwamanyikwe;
Izimpawu zokushoda kwe-insulin zithuthukisa - ukunqwabelana ku-serum yegazi yemikhiqizo yamafutha kanye ne-carbohydrate metabolism - ketones;
Isikhumba se-Itchy siyabonakala ku-groin emadodeni nasebunyeni ezigulini zabesifazane (okuyisizathu sokuya kudokotela we-gynecologist nodokotela wesikhumba bese wenza kube nzima ukuthola ukuxilongwa);
Ukwehla kwezwela emilenzeni, ukubanda okungapheli kwezandla nezinyawo;
Ukhathele ukungasebenzi komzimba futhi, ngenxa yalokho, ukuthambekela kwezifo zokukhunta nokuphulukiswa kwamanxeba okungekuhle;
Inhliziyo nokuntuleka kwemithambo.

Kodwa-ke, lezi zimpawu azizona izinkomba futhi ezimweni eziningi zokwelashwa akusona isizathu sokuya emtholampilo. Isifo sikashukela sohlobo II sivame ukutholakala nokuhlolwa kwegazi okujwayelekile njengokuzimisela okuphoqayo kwe-glucose esheshayo.

Ukudalwa kwesifo sikashukela sohlobo 2 kuvame ukwenzeka ngemuva kweminyaka engama-40 (kuyilapho abantu abanesifo sikashukela sohlobo 1 begula, imvamisa besebancane.

Kwesinye isikhathi, phakathi kokuqala kokukhula kwe-pathology kanye nokuxilongwa kwayo emtholampilo kudlula iminyaka eminingana, mayelana lapho kukhona izinkinga zesifo. Imvamisa, lesi sifo sitholakala etafuleni elihlinzayo, lapho iziguli zithuthukisa isifo sikashukela sonyawo bese ziba nezilonda zokulimala ngenxa yokunganele kwegazi.

Ezinye izinkinga zesifo sikashukela sohlobo 2 zingaba:

Ukuphazamiseka kwe-Ophthalmic (ukuthikameza okubukwayo, ukuthuthukiswa kwamabala angaboni, izinhlungu zamehlo - imiphumela ye-retinopathy yesifo sikashukela);
Ukuhlaselwa yisifo senhliziyo, i-angina pectoris, nokuhlaselwa yisifo senhliziyo okubangelwa ukwehluleka kwenhliziyo okukhulu;
Ukulimazeka emikhunjini yezinso - i-nephropathy;
Imivimbo ebangelwa izingozi ze-cerebrovascular.

Ngokuphikisana nesifo sikashukela sohlobo 1, izikhalazo zokuchama ngokweqile nokoma (i-polydipsia) cishe azikaze zibonwe.

Izimbangela zesifo

I-etiology yalesi sifo multifactorial. Ngaphezu kokumelana kwe-insulin yangempela, uhlobo 2 sikashukela luwumphumela wemiphumela eyinkimbinkimbi yezici eziningana.

Phakathi kwazo kukhona:

Isisulu sokuqothuka;
Amaphutha kokudla okunempilo: ukusetshenziswa kabi kwe-carbohydrate esheshayo (ehlanzekile) (ukubhaka, i-confectionery, ushukela, ushukela nokunye ukudla okusheshayo) ngokumelene nesizinda sokuqukethwe okuncishisiwe kokudla kwezitshalo ekudleni kwansuku zonke;
Isisindo ngokweqile (ikakhulukazi nge-visceral uhlobo lokukhuluphala, lapho inani lama-deposits amaningi lisesiswini - isisindo ngokweqile kuvimbela umzimba ekusebenziseni kahle i-insulin);
I-Hypodynamia (ukuntuleka kokunyakaza, umsebenzi wokuhlala phansi, ukuphumula ku-TV, ukuhamba njalo emotweni);
Umfutho wegazi ophezulu we-Arterial.

Enye into enethonya iminyaka yobudala besiguli - ngemuva kweminyaka engama-40, amathuba okuthola ukuphazamiseka kwesifo sikashukela ayanda ngokuqhubekayo. Ukukhuluphala cishe ngaso sonke isikhathi kuluphawu olufanayo lwesifo sikashukela sohlobo 2: ukukhuluphala kutholakala kumaphesenti angama-80 azo zonke iziguli.

Ngokuphikisana nesifo sikashukela sohlobo 1, uhlobo lwesifo olubhekwayo aluhlotshaniswa nokwakhiwa kwama-antibodies athize womzimba anomthelela obhubhisayo kwezicubu ze-pancreatic.

Ngakho-ke, uhlobo 2 sikashukela alunakubizwa ngokuthi isifo se-autoimmune.

Ngokuqondene nokwanda kwe-pathology, uhlobo 2 sikashukela luqoshwa kaningi kakhulu kunoshukela we-I. Izimpawu nezimpawu zefomu elivimbela i-insulin lesi sifo ziqala kancane futhi azibizi kangako. Lokhu kungenye umehluko obalulekile phakathi kwesifo sikashukela sohlobo 2. Ukuxilongwa kwalesi sifo kungenzeka kuphela ngesisekelo sokuhlolwa okugcwele nokungenamkhawulo esikhungweni sezokwelapha.

Isiphetho

Isifo sikashukela sohlobo II, ngaphandle kwako konke ukungathi sína, asikabi yisigwebo, futhi ukutholwa kusenesikhathi kanye nokwelashwa okufanele kungaba, uma kungenakuqedwa ngokuphelele, bese kucindezelwa ngokubonakalayo.

Uma kutholakala izinga eliphakeme lama-carbohydrate ekuqaleni kokukhula kwe-pathology, kwezinye izimo zomtholampilo kwanele ukushintsha uhlobo lokudla (ngaphandle kokudla okunama-carbohydrate okusheshayo, amafutha emifino nezilwane, inyama enamafutha) ukufeza ukuxolelwa kwesifo okuhlala isikhathi eside.

Kwesinye isikhathi ama-endocrinologists anquma ukulungiswa kokulashwa kwendlela yokuphila, okuholela ekunciphiseni isisindo nasekuqineni kwezinqubo ze-metabolic. Kuyadingeka kakhulu ukufeza izincomo zokwelashwa uma iziguli zingenandaba nokukhula kwezinkinga nokubukeka kwezimpawu eziphikisayo ze-pathology.

Ezimweni ezinzima kakhudlwana, kubekelwa ukwelashwa kwezidakamizwa: kutholakala izidakamizwa ezinciphisa ushukela eziqondisa izinga le-carbohydrate ku-serum yegazi. Kungasetshenziswa izidakamizwa ezikhulisa ukuzwela kwamaseli ku-glucose.

Njengoba lesi sifo singelapheki futhi siphindaphindeka (singakhula futhi ngemuva kokungabikho isikhathi eside), ukwelashwa kwesifo sikashukela sohlobo II cishe njalo kuyindlela yesikhathi eside, evame ukwenziwa impilo yonke, kudinga ukubekezela kweziguli nemikhawulo ebalulekile. Ngakho-ke, abantu abanalesi sifo kufanele bahambisane ngokushesha nezinguquko ezinkulu endleleni yabo yokuphila nokudla.

Send