Imvamisa, iziguli eziningi ezinesifo sikashukela sohlobo 2 azikwazi ukwehlisa amazinga kashukela ngenxa yokudla noma ukuzivocavoca zodwa. I-Metformin 1000 mg iyeza ukukusindisa - i-ejenti ye-hypoglycemic esetshenziselwa ukumelana ne-insulin kanye nokukhuluphala kwezifo ezinoshukela.
Lo muthi uthandwa kakhulu futhi ukhiqizwa emazweni amaningi. Kepha, njenganoma imuphi umuthi, unezimpawu zokuphikisana kanye nemiphumela emibi.
Umuthi obizwa ngeMetformin uyatholakala ngefomu lethebhulethi. Ngaphezu komthamo we-1000 mg, kukhona ukulungiswa isikhathi eside ngomuthi ka-500 no-850 mg. Leli thuluzi lingokwesigaba sama-greatuanides, okungukuthi, ama-hypoglycemic agents.
Isenzo sengxenye eyinhloko, i-metformin, asihlotshaniswa nokwenyuka kokukhiqizwa kwehomoni elawula ushukela wegazi. Okuqukethwe yithebhulethi elingu-1 lomuthi kufaka phakathi izinto ezifana ne-magnesium stearate, povidone K90, isitashi sommbila nabanye.
Umuthi usetshenziswa ezimeni ezinjalo:
- Uhlobo 2 isifo sikashukela sikhuluphele noma sikhuluphele.
- Njengokwengezwa kokwelashwa kwe-insulin ohlotsheni lokuqala lwe-pathology.
- Ngesikhathi sokuvimbela ukuguga.
- Ngesikhathi sokwelashwa kwe-ovary ecopolycystic.
- Ngokuphazamiseka kwe-metabolic.
Ngokuyisisekelo, ukusebenza kahle kwe-Metformin 1000 kuhlotshaniswa nokwelashwa kwesifo sikashukela sohlobo 2. Ibekelwe i-monotherapy, kanye nokungezwa kwezinye izidakamizwa ezonciphisa ushukela. Ngaphezu kwalokho, ngohlobo lokuqala lwe-pathology, leli thuluzi lihambisana nemijovo ye-insulin, uma lithathwe ngasikhathi sinye, linganciphisa isidingo se-hormone ngamaphesenti angama-25-50. Into enhle enjalo ifakazelwe ngokwesayensi.
Isidakamizwa sinconywa ukuthi sigcinwe kude nezingane zingafinyeleleki, emazingeni okushisa asekamelweni kungadluli i-25C. Isikhathi sokulondolozwa kwamathebulethi yiminyaka emi-3.
Imiyalo yokusebenzisa umuthi
Umuthi unqunywe ngudokotela owakha irejimithi yokwelashwa futhi abeke umthamo ofanele. Akunakwenzeka ukuthenga umuthi ekhemisi ngaphandle kadokotela. Imiyalo yokusebenzisa iMetformin 1000 ifakiwe kwiphakeji ngayinye. Ngaphambi kokuthatha umuthi, kufanele ufunde imiyalo.
Amathebulethi athathwa ngomlomo ngaphandle kokuwahlafuna futhi awaphuze ngamanzi. Umuthi ungaphuzwa uma udla noma ngemuva kokudla. Kubantu abadala, nge-monotherapy noma inhlanganisela yeMetformin 1000 nezinye izidakamizwa ezinciphisa ushukela, imithamo elandelayo ivunyelwe:
- Esigabeni sokuqala sokwelashwa, kuvunyelwe ukuthatha amaphilisi angu-0.5 (500 mg) izikhathi ezingama-2-3 ngosuku. Ngokuhamba kwesikhathi, umthamo wesidakamizwa ungakhuphuka ngokuya ngenqwaba yama-glucose egazini lesiguli.
- Ukulungiswa kokulashwa kunikeza umthamo wansuku zonke - kusuka ku-1500 kuya ku-2000 mg, okungukuthi, kuze kufinyelele kumathebulethi ayi-2. Ukugwema ukungahambi kahle okuhambisana nokuphazamiseka kwendlela yokugaya ukudla, kunconywa ukuhlukanisa ukusetshenziswa komuthi amahlandla ama-2-3 ngosuku.
- Isilinganiso esiphezulu somuthi ngu-3000 mg. Kufanele ihlukaniswe ngezindlela ezintathu.
Uma umuntu onesifo sikashukela ethathe isinqumo sokushintshela kuMetformin ngesinye isidakamizwa, okokuqala kufanele uyeke ukusetshenziswa kwawo.
Lapho kuhlanganiswa umuthi nokwelashwa kwe-insulin, iziguli eziningi ziyakwazi ukulawula ngempumelelo okuqukethwe kwe-glucose egazini. Ekuqaleni kokwelashwa, abantu abadala banikezwa ithebhulethi eyi-1 ngosuku (1000 mg). Ezinganeni (ezisukela eminyakeni eyi-10) nentsha, kuvunyelwe ukuthatha umuthi ezibhebheni ezingama-0.5 (500 mg) ngosuku ku-monotherapy nasekuhlanganiseni ne-insulin.
Ngemuva kwamasonto amabili ekwelashwa, kulungiswa ngokusekelwe ekuhlaziyweni kwezinga loshukela. Umthamo ophelele ebusheni ngamaphilisi ama-2 (2000 mg), ahlukaniswe ngemithamo emibili. Ezigulini esezikhulile, udokotela unquma imithamo, kucatshangelwa isimo sabo sempilo. Udokotela kumele aqaphele ikakhulukazi uma umsebenzi wezinso wesiguli uyehla lapho uthatha umuthi. Ukunquma ama-pathologies, kuhlaziywa kwenziwa ukuhlushwa kwe-creatinine ku-serum yegazi.
Inkambo yokwelashwa inganqunywa kuphela ngudokotela ohambelayo.
Contraindication kanye nemiphumela emibi
Kunezizathu ezithile zokuthi kungani ukusetshenziswa kwalesi sidakamizwa kungeke kwenzeke. Njengayo yonke eminye imithi, iMeformin 1000 inezinombolo eziningi zokuphikisana:
- Ukungabekezelelani komuntu ngamunye kwinto esebenzayo nezinto ezisizayo.
- Isimo sikashukela sikashukela, i-precoma, i-ketoacidosis yesifo sikashukela (okhubazekile we-carbohydrate metabolism).
- Ukungasebenzi kahle noma ukwehluleka kwezinso.
- Isimo sokuphelelwa ngamandla, ukushaqeka, ukutheleleka.
- I-pathologies e-acute noma engapheli evusa ukuthuthukiswa kokuphefumula, ukuhluleka kwenhliziyo, i-infarction ye-myocardial acute.
- Ukudluliselwa kokungenelela kokuhlinzwa, ukuba khona kokulimala okukhulu.
- Ukuphazamiseka kwesibindi, ukuthuthukiswa kokuhluleka kwesibindi.
- Ukuxiliswa komzimba ngotshwala, uphuzo oludakayo.
- Ukuzala nezingane.
- Sebenzisa izinsuku ezimbili ngaphambi nangemuva kokuhlolwa kwe-x-ray kanye ne-radioisotope usebenzisa into equkethe iodine.
- Izingane ezingaphansi kweminyaka eyi-10.
- Ukudla okunama-kilojoule angaphansi kuka-1000 kcal ngosuku.
- I-Lactic acidosis (ukunqwabelana kwe-lactic acid).
Ngokusebenzisa kabi umuthi noma i-overdose yayo, isiguli singathola ukusabela okungekuhle:
- Ukuphazamiseka kwemetabolic, okuvezwa yi-lactic acidosis. Lesi simo kungenzeka ngenxa malabsorption of Vitamin B12.
- Ukwephulwa kohlelo lwezinzwa, ngenxa yalokho, ushintsho ekunambithekeni.
- Ukuphazamiseka kokugaya ukudla, okubonakaliswa isicanucanu, ukugabha, ubuhlungu besisu, ukuntuleka kokudla.
- Ukucasuka kwesikhumba, ngokwesibonelo, ukuqubuka, i-erythema, ukulunywa.
- Ukwephulwa kwesibindi, ukubukeka kwe-hepatitis.
Imiphumela emibi ejwayelekile kakhulu yokuthatha iMetformin yizinkinga zokugaya ukudla. Zihambisana nokuvinjwa kokufakwa kweglue glucose. Ngenxa yalokho, i-carbohydrate Fermentation iqala, enomthelela ekwakhiweni kwezimpawu ezahlukahlukene. Ngemuva kwamasonto amabili ukusebenzisa lesi sidakamizwa, imiphumela enjalo ihamba yodwa. Ukuze unciphise izimpawu, udinga ukwephula isilinganiso silinganiswe ngemithamo eminingana ngosuku.
Ngaphezu kwalokho, ucwaningo luye lwabonisa ukuthi izingane ezineminyaka eyi-10 kuye kweyi-16 zithola imiphumela efanayo efanayo neyabaguli abadala.
Kusetshenziswa umuthi wokuthoba
Wonke umuntu uyazi ukuthi ukukhuluphala kuhambisana nesifo sikashukela. Ngakho-ke, iningi labantu abanesifo sikashukela abakhuluphele ngokweqile abakwazi ukuletha amazinga abo ashukela abejwayelekile.
Kepha ukulwa nokukhuluphala nakho kungaba nomphumela we-hypoglycemic kushukela. Umuthi iMetformin 1000 usetshenziswa iziguli eziningi ukunciphisa isisindo somzimba. Ukuze uthole umphumela omuhle kakhulu futhi uvikele imiphumela emibi, umuntu kufanele alandele izincomo eziningana:
- Qhubeka nenkambo yokwelashwa isikhathi esingeqile kwezinsuku ezingama-22.
- Hola indlela yokuphila esebenzayo.
- Thatha uketshezi olwengeziwe.
- Landela ukudla futhi uzenzele umkhawulo ekudleni.
Uma isiguli sifuna ukwehlisa isisindo ngokwejwayelekile futhi sikuguqule okuqukethwe ushukela, kufanele enze ukuzivocavoca okuhlukahlukene komzimba nsuku zonke. Ukuqala, ukuhamba okungenani imizuzu engama-30 kuzokwanela. Ngokuhamba kwesikhathi, ungashintsha imisebenzi yangaphandle ngemidlalo, ukubhukuda echibini, ukugijimela ekuseni, ama-Pilates, ukuqina komzimba nokuningi.
Lapho usebenzisa umuthi, ukondleka okubonakalayo kubaluleke kakhulu. Izinsizakalo kufanele zibe zincane. Ukudla okunamafutha, ukudla okuthosiwe, kanye nama-carbohydrate agaya ukudla kalula kufanele kungafakwa ekudleni. Ukudla kwesiguli kufanele kube nemifino ethe xaxa nezithelo ezingafakwanga, ukudla okugcwele ama-carbohydrate ayinkimbinkimbi nefayibha.
Ukuzilapha kuleli cala akukufanele, udokotela kuphela ozokwazi ukukhetha isilinganiso esifanele somuthi, ngemuva kokuhlola isimo sempilo sesiguli.
Ngaphezu kwalokho iMetformin 1000 ingathathwa hhayi ngabantu abakhuluphele kuphela, kodwa futhi nethambile, abathambekele kokugcwala.
Ukubuyekezwa kwezindleko nezidakamizwa
IMetformin 1000 ingathengwa yinoma ngubani kunoma iyiphi ikhemisi noma wenze i-oda online. Intengo yomuthi incike ekutheni iyasekhaya noma ingenisiwe yini. Njengoba umuthi usebenza futhi uthandwa emhlabeni wonke, ukhiqizwa emazweni amaningi. Izindleko zeMetformin 1000 zincike ezweni lezokwakha kanye nenkampani yezemithi ekhiqiza umuthi. Ngakho-ke iMetformin, ekhiqizwe endaweni yeRussian Federation, inendleko ebangeni kusuka kuma-ruble angama-196 kuye kwangama-305, ukulungiswa kokukhiqizwa kweSlovak eRussia Federation kubiza isilinganiso sama-ruble ayi-130. Umkhiqizo odabuka eHungary unentengo emaphakathi yama-ruble angama-314.
Singaphetha ngokuthi intengo yomuthi iphansi, ngakho wonke umuntu angathenga umuthi onjalo. Zinezinto eziphambili - i-metformin, ezihlukile komunye nomunye kwizakhi ezisizayo. Isiguli ngasinye sithenga umuthi osuselwa kumphumela olindelekile wokwelapha kanye namakhono wezezimali. Ngaphezu kwalokho, izidakamizwa ezifuywayo azibizi, kodwa zinomphumela ofanayo.
Ngokuqondene nombono wabathengi ngalesi sidakamizwa, muhle kakhulu. Ukubuyekezwa kweziguli eziningi kukhombisa ukwehla kwangempela kwamazinga kashukela kuya kumazinga ajwayelekile. Kulokhu, umuthi ukwazile ukwandisa ukugcwala okujwayelekile kwe-glucose egazini ngenqubo ende yokwelashwa. Phakathi kwezici ezinhle zalo muthi, ukusetshenziswa kalula nezindleko eziphansi kuyahlukaniswa.
Abaningi besifo sikashukela bathi iMetformin 1000 isiza ukukhipha amakhilogremu angeziwe. Ngasikhathi sinye, abanye babo bakwazile ukwehlisa isisindo esihle ngenxa yokulandela yonke imithetho ngesikhathi sokusetshenziswa kwezidakamizwa. Ukwehluleka ukusebenzisa amaphilisi kungathonyelwa yizinto ezinjengethamo elinganele, ukwelashwa okungajwayelekile kwesifo sikashukela, ukusetshenziswa kwezidakamizwa okungajwayelekile, nokungazinaki komuntu ngamunye ezingxenyeni zomuthi.
Umuthi unezinkinga ezithile. Zihlotshaniswa nokuba khona kwemiphumela emibi, ikakhulukazi ukuphazamiseka kokugaya ukudla, lapho umzimba womuntu usujwayela isenzo se-ejenti ye-hypoglycemic.
Imvamisa, lezi zimpawu zihamba zodwa.
Ama-ejenti afanayo we-hypoglycemic
Ngenxa yokuthandwa kwayo, iMetformin inamagama womqondo owodwa. Ukulungiselela okufanayo okuqukethe isakhi esisebenzayo kungahluka kuphela kubafundi. Le mishanguzo ifaka:
- Glyformin;
- Metfogamm;
- I-Bagomet;
- Amafutha amafutha;
- Glyminfor;
- UNova Met.
Lolu hlu lungandiswa ngezimali eziningi ezifanayo. Abantu abaningi bayazibuza ukuthi yimaphi amaphilisi ahamba phambili. Eqinisweni, akukho mehluko omkhulu, ngoba isakhi esiyinhloko sitholakala kuzo zonke lezi zidakamizwa. Ngakho-ke, isici esiyinhloko esithinta ukukhetha kwesidakamizwa intengo yaso.
Esimweni lapho umuthi iMetformin 1000 ungasifanele isiguli, sibangele ukusabela okubi kuye, udokotela angalungisa ukwelashwa ngokuchaza elinye ikhambi elifanayo. Isibonelo:
- I-Siofor isidakamizwa esihle kakhulu esinciphisa ushukela esingahlanganiswa nezinye izidakamizwa ezifana ne-salicylate, sulfonylurea, insulin nokunye. Ngokulashwa okuyinkimbinkimbi nalesi sidakamizwa, imiphumela elindelekile iyathuthuka. Intengo emaphakathi yomuthi (1000 mg) ingama-ruble angama-423.
- I-Glucophage ngesinye isidakamizwa esisebenzayo esinomphumela we-hypoglycemic. Ucwaningo lwakamuva lukhombisa ukuthi ukuthatha lo muthi kunciphisa amathuba okufa kusuka kushukela ngo-53%, ithuba lokuqalwa kwe-myocardial - ngo-35%, nokushaywa unhlangothi - ngama-39%. Ngokwesilinganiso, isidakamizwa (850 mg) singathengwa ngama-ruble angama-235.
- I-Diagnizide isidakamizwa esinciphisa ukumelana kwe-insulin futhi sikhuphule umphumela we-hormone enciphisa ushukela - i-insulin. Ingxenye eyinhloko yalo muthi izidalwa ze-sulfonylurea. Umuthi awuthathwe ngokudakwa okungapheli, i-phenylbutazone kanye ne-danazole. Izindleko ezimaphakathi zomuthi (2 mg, amaphilisi angama-30) ngama-ruble angama-278.
- I-altar iqukethe isakhi esisebenzayo - i-glimepiride, ekhipha i-insulin ngamangqamuzana e-beta pancreas. Ngakho-ke, leli thuluzi lisetshenziswa ekwelapheni isifo sikashukela nokukhuluphala. Ngaphezu kwalokho, umuthi unemiphumela eminingi emibi okumele icatshangwe ngaphambi kokuyisebenzisa. Intengo evamile yomuthi (3 mg, ama-30 ama-pcs.) Angama-ruble angama-749.
Futhi-ke, iMetformin 1000 iyinhlangano esebenza ngempumelelo ye-hypoglycemic esizisungule ngokwayo emazweni amaningi omhlaba. Ukusetshenziswa kwaso kungenzeka kuphela ngemuva kokubonana nodokotela, ngoba umuthi unezici ezithile eziphikisayo nemiphumela emibi. Ngokusetshenziswa okufanele kwamathebulethi, umuntu onesifo sikashukela uyokhohlwa ngenkinga ye-hyperglycemia isikhathi eside aze akwazi ukulahlekelwa ngamakhilogremu angeziwe.
Kule vidiyo ekulesi sihloko, u-Elena Malysheva, kanye nochwepheshe, bazokhuluma ngeMetformin.
