I-ascorbic acid engenashukela ikhulisa isenzo se-insulin futhi ikhulisa ukumelana komzimba ukungena kokungenwa kwezifo ze-pathological kuyo.
Umuthi osetshenziselwa ushukela uwuketshezi olucacile.
Umuthi ukhiqizwa kuma-ampoules ama-milliliters ayi-1-2.
Umuthi kufanele ugcinwe endaweni emnyama, izinga lokushisa lapho kugcinwa khona umuthi kumele lingabi ngaphezu kwama-25 degrees. Gcina ungafinyeleleki ezinganeni.
Impilo yeshalofu yesidakamizwa ayidluli unyaka owodwa.
Ukwakheka kwalesi sidakamizwa kufaka phakathi okulandelayo:
- isakhi esiyinhloko esisebenzayo somuthi yi-ascorbic acid;
- amakhompiyutha asizayo - i-sodium bicarbonate, i-sodium sulfite, amanzi ahlanziwe ngomjovo.
In ukwakheka kwe-ampoule eyodwa, kuya ngevolumu ephelele, iqukethe ama-50 noma 100 mg wekhompiyutha enkulu esebenzayo.
Umuthi unomsebenzi we-vitamin C, uthinta izinqubo ze-metabolic emzimbeni womuntu. Isidumbu sodwa asikwazi ukuhlanganisa leli khompiyutha.
I-Ascorbic acid ibamba iqhaza ekuqinisekiseni ukulawulwa kokuphendula kabusha kwe-redox emzimbeni, isiza ukunciphisa ukuncipha kodonga lwe-vascular.
Ukwethulwa komthamo owengeziwe we-ascorbic acid emzimbeni kusiza ukunciphisa isidingo somuntu:
- uvithamini B1;
- uvithamini B2;
- Vitamin A
- Vitamin E
- i-folic acid;
- i-pantothenic acid.
I-Acid ibandakanyeka ngenqubo yezinqubo ze-metabolic:
- i-phenylalanine;
- i-tyrosine;
- i-folic acid;
- norepinephrine;
- i-histamine;
- insimbi;
- ukulahlwa kwama-carbohydrate;
- i-lipid synthesis;
- amaprotheni;
- i-carnitine;
- izimpendulo zokuzivikela komzimba;
- i-hydroxylation ye-serotonin;
- kuthuthukisa ukufakwa kwensimbi engeyona eye-heminic.
I-Ascorbic acid ibamba iqhaza ngokuqinile emgomweni wokuhambisa we-hydrogen kukho konke ukuvela kwe-metabolic okwenzeka emzimbeni.
Ukwethulwa kwemithamo eyengeziwe ye-ascorbic acid emzimbeni kuvimbela umzimba futhi kusheshise ukonakaliswa kwe-histamine futhi kusize ekuvimbeleni ukwakheka kwama-prostaglandins.
Izinkomba zokusetshenziswa kanye ne-contraindication
Inkomba yokusetshenziswa kwe-ascorbic acid ubukhona be-hypo- ne-avitominosis C emzimbeni womuntu. I-Ascorbic acid isetshenziswa lapho kuba nesidingo sokubuyisa ngokushesha uvithamini C emzimbeni.
Ukusetshenziswa kwe-ascorbic acid kushukela kunomphumela wokwehlisa ushukela wegazi ngaphandle kwamaphilisi sibonga imijovo. I-Ascorbic acid ingathinta umzimba ngezindlela ezihlukile, kuya ngentshisakalo yokuqala yoshukela emzimbeni.
Ngokuqukethwe ushukela ophansi, i-ascorbic acid inyusa izinga le-glucose ku-plasma yegazi lesiguli esinesifo sikashukela i-mellitus. Ngokugxilisa ushukela omningi, okuvame ukubonwa kwabanesifo sikashukela, le nkomba iyancipha.
Ukubuyekezwa kweziguli ezinesifo sikashukela kubonisa ukuthi ukuthatha i-ascorbine kunomthelela ekujwayeleni ushukela emzimbeni.
Ukusetshenziswa kwalesi sidakamizwa kufanelekile ezimweni lapho senziwa:
- Ukudla komzali.
- Izifo zesisu ziyelashwa.
- Isifo sika-Addison.
Isidakamizwa sisetshenziswa ekwelapheni isifo sohudo esiphikelelayo, ngesikhathi sokuxhuma kabusha kwamathumbu amancane, lapho kukhona isilonda se-peptic esigulini nangesikhathi se-gastrectomy.
Ukusetshenziswa kwomuthi akunconywa uma kukhona ukuzwela okwengeziwe emzimbeni wesiguli kuya ezingxenyeni ezakha umuthi.
Ukwethulwa kwemithamo emikhulu ye-ascorbic acid lapho kukhona isiguli kubekiwe:
- I-Hypercoagulation;
- I-Thrombophlebitis;
- ukuthambekela kwe-thrombosis;
- isifo sezinso;
- ushukela we-glucose-6-phosphate dehydrogenase.
Kufanele kuqashelwe ikakhulukazi lapho kusetshenziswa i-ascorbic acid esimweni lapho isiguli sine-hyperoxaluria, ukwehluleka kwezinso, i-hemochromatosis, i-thalassemia, i-polycythemia, i-leukemia, i-sideroblastic anemia, i-sickle cell anemia, i-neoplasms enobungozi.
Imiyalo yokusebenzisa umuthi
Isixazululo sokujova umuthi sikhonjwe ngomjovo we-intravenous noma we-intramuscular. Ukwethulwa komuthi kufanele kwenziwe ngezinjongo zokwelapha kumthamo we-0,05-0.15 g, ohambelana ne-1-3 ml nge-ascorbic concentration ye-50 mg / ml solution.
Umthamo omkhulu ovunyelwe wokuphatha owodwa ngu-0,2 g noma 4 ml.
Umthamo wansuku zonke kufanele ungabi ngaphezu kwegramu eyi-1 yesisombululo se-20 ml kubantu abadala. Kumntwana, umthamo wansuku zonke kufanele ungabi ngaphezu kwe-0,05-0.1 g / usuku, okuyi-1-2 ml. Isikhathi sokwelashwa kwe-ascorbic acid kuncike kuhlobo kanye nenkambo yesifo.
Ngenqubo yokusebenzisa umuthi esigulini, kungaba nemiphumela emibi, okuvela ukubukeka:
- Isiyezi ngokuphathwa ngokushesha komuthi.
- Imizwa yokudinwa.
- Uma usebenzisa imithamo emikhulu, ukubonakala kwe-hyperoxaluria, i-nephrolithiasis kungenzeka ilimaze izinsiza kusebenza ze-glomerular zezinso.
- Ukwehla okungenzeka kokuvunyelwa kwezindonga zama-capillaries.
- Ukwethulwa kwemithamo emikhulu yesidakamizwa, kungenzeka kakhulu ukuthi kube nokuqubuka kwesifo sikashukela kanye ne-hyperemia yesikhumba, ukuthuthukiswa kokuqhaqhazeka kwe-anaphylactic.
Ukuphepha kokuphepha
Lapho unquma i-ascorbic acid, ukunakwa kufanele kukhokhwe ekusebenzeni okufanele kwezinso zesiguli, ngoba i-ascorbic acid inomphumela ovuselelayo ekuhlanganiseni kwamahomoni e-corticosteroid.
Kwenqatshelwe ukusebenzisa i-acid uma isiguli sinwebeka kakhulu futhi sivelisa kakhulu amangqamuzana omdlavuza womdlavuza we-metastatic.
I-Ascorbic acid yi-ejenti yokunciphisa, okufanele icatshangelwe lapho kwenziwa izivivinyo zaselebhu, ngoba ingaphambukisa imiphumela yocwaningo olunjalo.
Izindleko zomuthi emakhemisi eRussia zingama-ruble angama-33 - 45.
Ividiyo ekulesi sihloko ikhuluma ngezinzuzo ze-ascorbic acid.