Izimpawu zombili ze-pancreatitis ezingamahlalakhona nezizimbi azicacanga. Izimpawu zivame ukungabavumeli odokotela ukuthi bahlonzwe ngokufanele, ngoba lezi zibonakaliso zingabantu bezinye izifo ezithile.
Lapho wenza ukuxilongwa, ukubaluleka okukhulu kunikezwa ukuhlaziya. Izinkomba kanye noshintsho ezindundwini, kumchamo nasegazini kuyafundwa, okuvumela ukunquma ngokunemba okukhulu ukuthi ngabe ikhona inqubo yokuvuvukala kumanyikwe.
Ukuhlolwa kwegazi okwelashwa
Nge-pancreatitis, ukuhlolwa kwegazi komtholampilo kudlala indima ethile yokusiza. Ukuhlaziywa kwenza sikwazi ukubona ukuthi inqubo yokuvuvukala ikhona. Ukuhlaziywa kwemitholampilo kukhombisa nokuphelelwa ngamandla komzimba.
Nge-pancreatitis esintwini, izici ezilandelayo ekuhlaziyweni kwegazi kwezempilo ziyabonakala:
ukwehla kwenani lamangqamuzana egazi abomvu namazinga e-hemoglobin, ngenxa yokulahleka kwegazi kanye nenkomba yokuthi kungenzeka ukuthi i-hemorrhagic complication ye-pancreatitis;
ukwanda kwenani lamaseli amhlophe egazi, kwesinye isikhathi kaningi, ngenxa yokuvuvukala;
ukukhuphuka kwe-hematocrit kukhombisa ukwephulwa kwemali esele ye-electrolyte-water.
ukukhuphuka kwezinga le-erythrocyte sedimentation rate uphawu lokuphendula okungapheli kokuvuvukala.
Amakhemikhali egazi
Ukuxilongwa kwe-pancreatitis akuphelile ngaphandle kokuhlolwa kwegazi okune-biochemical. Kwenza ukuthi kunqume izinga lokusebenza komzimba wonke.
Nge-pancreatitis, ushintsho ekwakhekeni kwamakhemikhali egazi kungabonakala, ikakhulukazi, kungaba:
- ukwanda kwama-amylase. I-Amylase iyi-enzyme ye-pancreatic ephula isitashi;
- amazinga akhuphukayo e-lipase, elastase, phospholipase, trypsin;
- ukukhuphuka koshukela wegazi ngenxa yokungasebenzi okwanele kokuvikelwa kwe-insulin;
- amazinga akhuphukayo ama-transaminases;
- ukukhuphuka kwe-bilirubin kuwuphawu lwelabhoratri olwenzeka uma ipheshana elihlanganisiwe livinjelwe amapancisi akhulisiwe;
- ukwehlisa izinga lamaprotheni aphelele, njengomphumela wendlala-yamaphrotheni.
Ukwanda kwenani lama-enzyme e-pancreatic, ikakhulukazi, i-amylase, yisibalo esibaluleke kakhulu ekutholakaleni kwalesi sifo.
Odokotela bathatha igazi ukuze bahlaziye ama-biochemical ngokushesha nje lapho isiguli sifika esibhedlela. Kamuva, izinga lama-amylase linqunywa ukuze kulawulwe isimo se-pancreas ku-dynamics.
Ukwanda kwenani lama-enzymes e-pancreatic egazini naphezu kokukhula kobuhlungu esiswini kungabonisa ukuthi lesi sifo siyaqhubeka noma sinikeza ezinye izinkinga.
Ukucaciswa okuncane kakhulu ukunqunywa kwe-lipase egazini. Iqiniso ukuthi inani lale enzyme likhuphuka hhayi kuphela nge-pancreatitis.
Ukuhlaziywa kwesiguli esingaphezu kwengxenye yeziguli ezine-biliary tremology kanye ne-pathology yesibindi kukhombisa ukwanda kokuhlushwa kwe-lipase.
Kodwa-ke, i-lipase yegazi ihlala isikhathi eside kune-amylase, ngakho-ke kufanele kunqunywe lapho umuntu elaliswa esibhedlela isikhathi esithile kuphela ngemuva kokuqalwa kwezimpawu ze-pancreatitis.
Ukunquma ukungasebenzi kahle kwe-pancreatic, kubalulekile ukwazi izinga le-serum elastase. Kwi-pancreatitis eyingozi, inani elithile lale enzyme livame ukubonwa. Ngaphezu kwalokho, lapho i-serum elastase iyanda, indawo enkulu ye-necrosis kumakhanseya, iba yimbi kakhulu ukwanda kwesifo, kanye nezimpawu zokuphambanisa ushintsho esibindini namanyikwe kusiza ukukuqinisekisa lokhu.
Ukunemba okuphezulu kakhulu kokuthola ubukhulu bokulimala kwesitho ku-plasma neutrophil elastase. Kepha le ndlela ayenziwa ezindaweni eziningi zokubeletha, yenziwa kuphela emitholampilo yesimanje kakhulu yezwe.
Izinga le-elastase, ngokungafani namanye ama-enzyme e-pancreatic, lihlala liphakeme kubo bonke abantu abagulayo izinsuku eziyishumi kusukela ekuqaleni kwalesi sifo.
Uma uqhathanisa, ngasikhathi sinye, ukwanda kwe-amylase kuqoshwa kuphela esigulini sesihlanu ngasinye, izinga le-lipase - akukho ngaphezu kweziguli ezingama-45-50%.
Ngakho-ke, ukunqunywa kwenqanaba le-serum elastase kuyindlela ebalulekile yokuxilonga yokuthola i-pancreatitis kubantu abangeniswe esibhedlela ngeviki elilodwa kamuva noma ngemuva kokuqala kwezimpawu zokuqala zokwelashwa.
Ukuhlaziywa kwe-Fecal
Kwi-pancreatitis, ukuhlaziywa kwe-fecal kunquma ukuthi yiliphi izinga langempela le-pancreas elisebenzayo. Lapho ukwehla kwama-enzymes wokugaya ukudla kuncipha, inqubo yokugaya kwamafutha ihlala ihlupheka ekuqaleni. Lezi zinguquko zingalandelelwa kalula ezindlebeni. Ukuboniswa okulandelayo kukhombisa ukuthi umsebenzi we-pocrreatic pancreatic ukhubazekile:
- ukuba khona kwamafutha ezinduneni;
- ukudla okungasalungiswa okusele ezinduneni;
- uma uvimba imigqa ye-bile - izindle zizokhanya.
Ngokuphulwa okubonakalayo komsebenzi we-pocrreas, ushintsho ezindlini lubonwa ngeso elinqunu:
- Amendlu angagezwa kahle ezindongeni zangasese,
- inendawo ekhanyayo
- iphunga lesitulo liyaphikelela futhi alilijabulisi,
- Izihlalo okuvulekile neze njalo.
Ukugcotshwa okunjalo kuvela ngenxa yokubola kwamaphrotheni angalungisiwe emathunjini.
Kumele kuqashelwe ukuthi ukuze kucaciswe izici zomsebenzi we-grey ye-exocrine, ukutadisha izindundana akuyona into ebaluleke kakhulu. Kulokhu, kaningi, ezinye izivivinyo zisetshenziselwa i-pancreatitis.
Njengomthetho, ukwephulwa emsebenzini we-pancreas kutholakala ngenye indlela: kufakwa iphenyi bese kuthathwa ujusi we-pancreatic ukuze uhlolwe.
Okunye ukuhlola ukuthola i-pancreatitis
Kusetshenziswa izivivinyo eziningi zelebhu ukuhlonza i-pancreatitis. Ngezansi kukhona okuyisisekelo kunazo zonke:
Ukunqunywa kokuhlushwa kwe-trypsin inhibitors egazini. Lapho inani elincane lenani labo kuyi-plasma, kulapho kubhubhisa khona amanyikwe. Ngakho-ke, isibikezelo sizoba sibi.
Ukunqunywa kwe-trypsin engasebenzi. Udokotela ubeka le ndlela ngendlela engejwayelekile, ngoba ukufana kwayo kungama-40% kuphela. Lokhu kusho ukuthi ezimweni ezingama-60%, i-trypsin ye-immunoreactive akusho ukuthi i-pancreatitis, kepha esinye isifo noma ukuphazamiseka, ngokwesibonelo, ukwehluleka kwezinso, noma i-hypercorticism, ne-cholecystitis pancreatitis nakho kunqunywa.
Ukunqunywa kokuqukethwe kwe-trypsinogen kumchamo. Le ndlela iyindlela yokufundisa, eqondile kakhulu futhi enozwela. Lapha, cishe isiqinisekiso esiseduze kwe-100%, ungenza ukuxilongwa okulungile. Akuvamile ukusetshenziswa, ngoba kuyabiza futhi akutholakali kuzo zonke izikhungo zezokwelapha.
Uma uhlanganisa izindlela zokuxilonga izinsimbi, unaka ukubonakaliswa kwezifo zokulimala kwe-pancreatic, khona-ke ukuhlolwa kwelabhoratri kwenza ukuthi kunqume ngokushesha ukuba khona kwe-pancreatitis.
Inani elifundisayo kakhulu le-gastroenterologist ukunqunywa kwezinga lama-enzymes egazini lesiguli. Ngosuku lokuqala, udokotela kufanele ahlole izinkomba ze-pancreatic amylase, ngemuva kwezinsuku ezimbalwa, kufundwa izinga le-elastase ne-lipase.
