Umqondo wokumelana ne-insulin kanye nezizathu zokuthuthuka kwayo

Ukubaluleka kwe-insulin ezinqubweni ze-metabolic zomzimba womuntu kunzima kakhulu ukuqiniseka ngokweqile. Kwenzekani ngokumelana ne-insulin? Kungani ivela futhi ingaba yingozi kanjani? Funda kabanzi ngalokhu, kanye nokwephula ukuzwela kwe-insulin ezimeni ezihlukile nangokuphathelene nokwelashwa kwalesi sifo.

Kuyini ukumelana ne-insulin?

Ukumelana ne-insulin ukwephula ukusabela kwe-metabolic ukuphendula isenzo se-insulin. Lesi yisimo lapho amaseli ezinqunyelwe ezinamafutha amaningi, izicubu zomzimba kanye ne-hepatic eyekayo ukuphendula emiphumeleni ye-insulin. Umzimba uyaqhubeka nokuhlanganiswa kwe-insulin ngesivinini esijwayelekile, kepha awusetshenziswa ngesilinganiso esifanele.

Leli gama liyasebenza emiphumeleni yalo ekusebenzeni kwe-metabolism yamaprotheni, ama-lipids kanye nesimo jikelele sohlelo lwe-vascular. Lo mkhuba ungathinta noma iyiphi inqubo eyodwa ye-metabolic, noma yonke ngasikhathi sinye. Cishe kuzo zonke izimo zemitholampilo, ukumelana ne-insulin akubonwa kuze kube sekubonakaleni kwama-metabolic metabolism.

Zonke izakhamzimba emzimbeni (amafutha, amaprotheni, ama-carbohydrate) njengendawo yokugcina amandla asetshenziswa ngezigaba usuku lonke. Lo mphumela wenzeka ngenxa yesenzo se-insulin, ngoba izicubu ngamunye uzwela ngokuhlukile kuzo. Le ndlela yokusebenza ingasebenza kahle noma ingasebenzi kahle.

Ngohlobo lokuqala, umzimba usebenzisa i-carbohydrate nezinto ezinamafutha ukwenza ama-molecule e-ATP. Indlela yesibili ibonakala ngokukhanga kwamaprotheni ngenhloso efanayo, ngenxa yalokho umphumela we-anabolic wamamolekyuli eglue wehla.

Izinqubo ziyaphazamiseka:

1. Indalo ye-ATP;
2. umphumela we-insulin ushukela.

Izizathu zokuthuthuka

Ososayensi okwamanje abakwazi ukubiza izizathu eziqondile ngoba umuntu abonakala emelana ne-insulin. Kuyacaca ukuthi kuvela kulabo abaphila impilo yokungazweli, abakhuluphele ngokweqile, noma abamiselwe izakhi zofuzo. Imbangela yalesi simo kungenzeka futhi kube ukwelashwa kwezidakamizwa nezidakamizwa ezithile.

Uma elinye lamaphuzu alandelayo likhona kuwe, khona-ke kungenzeka uthinteke ukwephulwa kokuzwela kwe-insulin:

• Iminyaka engaphezu kuka-40;
• Ungowesilisa onama-girth angaphezu kuka-103 cm, ungowesifazane onama-girth angaphezu kwama-88;
• Ezinye izihlobo zakho ezingekho kude ziyahlupheka, zinesifo sikashukela, isifo sokuqina kwemithambo yegazi, noma umfutho wegazi ophezulu;
• Ukubhema
• Ukudluliselwa kwesifo sikashukela esingumlando;
• I-Atherossteosis;
• Amanani akhulayo we-triglyceride;
• Izinga elehlisiwe lama-lipoprotein aphezulu;
• I-Polycystic ovary syndrome.

Izimpawu zalo mkhuba

Ukwephula umuzwa we-insulin kungahle kuhambisane nezimpawu ezithile. Kodwa-ke, kunzima ukuthola ukuthi lo mkhuba bawubona kuphela.

Ngokumelana ne-insulin, umuntu unezimpawu ezilandelayo:

• Kuba nzima ukuthi isiguli sigxilise ingqondo;
• Kunoshukela omningi egazini;
• Ukuqhakaza. Amagesi amaningi wamathumbu avela ekudleni kwe-carbohydrate. Njengoba ukungasebenzi kwabo kokudla kukhubazekile, umsebenzi wegaya wokugaya uyahlupheka;
• Ngemuva kokudla, ngokushesha ufuna ukulala;
• Ugxuma olunamandla ekucindezelweni kwegazi;
• Ukuchama kaningi;
• Umuzwa wokuqubuzela emilenzeni;
• Ukuvuleka kwesisindo okwenzeka njalo;
• Umile njalo;
• Ukubukeka okungenangqondo kwamaqhubu;
• Ukuvuselelwa kwesikhathi eside komonakalo;
• Isisindo somzimba kanye nobunzima bokulahla. Idiphozithi yamafutha yenziwe yasendaweni ikakhulukazi esiswini. Odokotela baphinde bakholelwe ukuthi isisindo esithe xaxa sibuye sishukumise ukukhula kwe-insulin ukumelana;
• Uhlala elambile;
• Ukuhlolwa kwegazi kwembula ama-triglycerides aphezulu;
• Izimo ezicindezelayo. Ngenxa yokuntuleka komphumela we-insulin nokuphazamiseka kwe-metabolic, isiguli singase sibhekane nokuphazamiseka okuhlukahlukene kwengqondo, kufaka phakathi ukudangala.

Ukumelana ngokweqile kanye ne-Insulin

Ukukhuluphala kungenye yezinto eziphambili ezisongela phambili ekuthuthukiseni ukumelana ne-insulin. Ukunquma izimfuneko zokuzwela kokulimala kwe-insulin kanye ne-metabolic syndrome ngokuvamile, kufanele wazi inkomba yakho yobukhulu bomzimba. Le nombolo iphinde isize ekuboneni isigaba sokukhuluphala kanye nokubala ubungozi bokuthola izifo zohlelo lwethambo nenhliziyo.

Inkomba ibhekwa ngokuya ngefomula: I = m / h2, m isisindo sakho ngamakhilogremu, h ukuphakama kwakho ngamamitha.

Ingabe lokhu kwephula umthetho kuyingozi?

Le pathology iyingozi ngokuvela kwezifo ezalandela. Okokuqala, uhlobo 2 sikashukela.

Ezinqubweni zesifo sikashukela, izicubu zemisipha, isibindi namafutha zithinteka ikakhulu. Njengoba umuzwa we-insulin uqothuliwe, ushukela uyaphela ukuthi udliwe ngobuningi bawo. Ngenxa yesizathu esifanayo, amaseli wesibindi aqala ukukhiqiza ushukela ngokuqhekeka phansi i-glycogen futhi ahlanganise noshukela kusuka kumakhemikhali e-amino acid.

Ngokuqondene nezicubu ze-adipose, umphumela we-antilipolytic kuwo uyancipha. Ezigabeni zokuqala, le nqubo inxephezelwa ngokuthuthukisa ukwakheka kwe-insulin kumanyikwe. Ezigabeni ezithuthukile, izinqolobane ezinamafutha zihlukaniswa ngamangqamuzana ama-asidi wamahhala nama-glycerol, umuntu wehlisa isisindo.

Lezi zingxenye zingena esibindini bese kuba nama-lipoprotein aphansi. Lezi zinto ziqongelela ezindongeni ze-vascular futhi zivuse ukuthuthukiswa kwe-atherosulinosis. Ngenxa yazo zonke lezi zinqubo, kukhipha ushukela omningi egazini.

I-Nocturnal Insulin Resistance

Umzimba uzwela kakhulu i-insulin ekuseni. Lokhu kuzwela kuvame ukuba buthaka phakathi nosuku. Ngomzimba womuntu, kunezinhlobo ezi-2 zokunikezwa kwamandla: umbuso wobusuku nemini.

Esikhathini sasemini, iningi lamandla lithathwa ikakhulukazi kusuka kushukela, izitolo ezinamafutha azithinteki. Ngokuphambene nalokho, kwenzeka ebusuku, umzimba uzihlinzeka ngamandla, okhishwa emafutheni e-fatty, akhishwa egazini ngemuva kokuwohloka kwamafutha. Ngenxa yalokhu, umuzwa we-insulin ungakhubazeka.

Uma udla ikakhulukazi kusihlwa, khona-ke umzimba wakho kungenzeka ungakwazi ukubhekana nevolumu lezinto ezingena kulo. Lokhu kungaholela ezinkingeni ezinkulu zempilo.

Okwesikhashana, ukuntuleka kwe-insulin ejwayelekile kunxephezelwa ngokwanda kwalokho kwento kumaseli we-pancreatic beta. Lesi simo sibizwa nge-hyperinsulemia futhi singophawu lwesifo sikashukela esibonakalayo. Ngokuhamba kwesikhathi, amandla amangqamuzana okukhiqiza i-insulin ngokweqile ayancipha, ukuqina koshukela kuyanda, futhi umuntu uba nesifo sikashukela.

Futhi, ukumelana ne-insulin kanye ne-hyperinsulinemia kuyizinto ezikhuthazayo zokuthuthukisa izifo zohlelo lwethambo nenhliziyo. Ngenxa yesenzo se-insulin, ukwanda kanye nokufuduka kwamaseli wemisipha ebushelelezi, ukwanda kwama-fibroblasts, kanye nokuvinjwa kwezinqubo ze-fibrinolysis kwenzeka. Ngakho-ke, ukukhuluphala kwemithambo kwenzeka ngayo yonke imiphumela elandelayo.

Ukumelana nokukhulelwa

Amamolekyuli we-glucose angumthombo wamandla ayisisekelo womama nengane. Ngesikhathi sokukhula kwezinga lokukhula kwengane, umzimba wayo uqala ukudinga ushukela owengeziwe. Into ebalulekile ukuthi kusukela ku-3rd trimester yokukhulelwa, izidingo ze-glucose zidlula ukutholakala.

Imvamisa, izingane zinoshukela wegazi ophansi ukwedlula omama. Ezinganeni, lokhu kucishe kube ngu-0.6-1.1 mmol / ilitha, kuthi kwabesifazane kuba ngu-3.3-6.6 mmol / lit. Lapho ukukhula kwesibeletho kufinyelela inani eliphakeme, umama angahlakulela ukungazweli komzimba ku-insulin.

Wonke ushukela ongena emzimbeni kamama ngokuyisisekelo awangenwa kuwo futhi uqondiswe kabusha kwi-fetus ukuze ungabi nokuntuleka kwezakhi zomzimba ngesikhathi sokukhula.

Lo mphumela ulawulwa yi-placenta, okuwumthombo oyisisekelo we-TNF-b. Cishe i-95% yale nto ingena egazini lowesifazane okhulelwe, konke okunye kungena emzimbeni wengane. Ukwanda kwezinga le-TNF-b okuyimbangela eyinhloko yokuphikiswa kwe-insulin ngesikhathi sokukhulelwa.

Ngemuva kokuzalwa kwengane, izinga le-TNF-b lehla ngokushesha futhi ngokufana, ukuzwela kwe-insulin kubuyela kokujwayelekile. Izinkinga zingenzeka kwabesifazane abakhuluphele ngokweqile, ngoba bakhiqiza kakhulu i-TNF-b kunabesifazane abanesisindo somzimba esijwayelekile. Kwabesifazane abanjalo, ukukhulelwa cishe njalo kuhambisana nezinkinga eziningi.

Ukumelana ne-insulini kuvame ukungashabalali ngisho nangemva kokubeletha, kukhona kakhulu%% wokuvela kwesifo sikashukela mellitus. Uma ukukhulelwa kuyinto evamile, ukumelana nakho kuyisici esisizayo ekuthuthukiseni ingane.

Ukwephulwa kokuzwela kwe-insulin ezinganeni

Kubantu abasebusheni, ukumelana ne-insulin kuvame ukuqoshwa. Iqiniso elithandekayo ukuthi ukucwilisa ushukela akukhuphuki. Ngemuva kokudlula kokufikisa, isimo sivame ukwenziwa njengokujwayelekile.

Ngesikhathi sokukhula okunamandla, ama-hormone e-anabolic aqala ukwakheka kakhulu:

1. Insulin
2. Ukukhula kwehomoni.

Yize imiphumela yazo ihlukile, i-amino acid metabolism ne-glucose metabolism ayihlupheki nganoma iyiphi indlela. Nge-hyperinsulinemia ehlangene, ukukhiqizwa kwamaprotheni kuyathuthuka futhi ukukhula kuyashukunyiswa.

Imiphumela ehlukahlukene ye-metabolic ye-insulin isiza ukuvumelanisa ukuzala nezinqubo zokukhula, kanye nokugcina ukulingana kwezinqubo ze-metabolic. Umsebenzi onjalo oguqukayo unikeza ukonga amandla ngokudla okunganele, kusheshisa ukuthomba kanye nekhono lokukhulelwa futhi ubelethe inzalo enezinga elihle lokudla.

Lapho ukuthomba kuphela, ukugcwala kwama-hormone ocansi kuhlala kuphezulu, futhi ukunganakwa kwe-insulin kunyamalale.

Ukwelashwa kwe-insulin

Ngaphambi kokuqala ukulwa nokulwa ne-insulin, odokotela bahlola isiguli. Ekutholakalweni kwesifo sikashukela sangaphambi kwesifo sikashukela nohlobo 2, kusetshenziswa izinhlobo eziningana zokuhlolwa kwelebhu:

• Ukuhlolwa kwe-A1C;
• Ukuhlolwa okusheshayo kwe-plasma glucose;
• Ukuhlolwa kokubekezelela kwe-glucose yomlomo.

Uhlobo 2 sikashukela lubonakala ngo-6.5% ekuhlolweni kwe-A1C, ushukela osuka ku-126 mg / dl futhi umphumela wokuhlolwa kokugcina ungaphezu kuka-200 mg / dl. Esimweni sesifo sikashukela, inkomba engu-1 ngu-5.7-6.4%, owesibili ngu-100-125 mg / dl, owokugcina uyi-140-199 mg / dl.

Ukwelashwa kwezidakamizwa

Izinkomba eziphambili zalolu hlobo lokwelashwa yinkomba yesisindo somzimba esingaphezu kwama-30, ingozi enkulu yokuba nezifo zemithambo yenhliziyo kanye nenhliziyo, kanye nokuba khona kokukhuluphala.

Ukwandisa uzwela we-glucose, kusetshenziswa izidakamizwa ezilandelayo:

• IBiguanides
  Isenzo salezi zidakamizwa sihloselwe ukuvimbela i-glycogeneis, ukunciphisa ukukhiqizwa kwamakhemikhali kashukela esibindini, ukuvimbela ukufakwa kweshukela emathunjini amancane, nokwenza ngcono ukuvikelwa kwe-insulin.
• I-Acarbose
  Enye yezindlela eziphephe kunazo zonke zokwelapha. I-Acarbose iyi-blocker ye-alpha-glucosidase evuselelekayo esepheshaneni elingenhla lesisu. Iphazamisa inqubo ye-polysaccharide ne-oligosaccharide cleavage kanye nokufakwa ngaphakathi kwalezi zinto egazini, futhi amazinga e-insulin ayancipha.
• I-Thiazolidinediones
  Khulisa ukuzwela kwe-insulin kwimicu yemisipha namafutha. Lawa ma-ejenti avusa inani elithile lezinhlobo zomzimba ezibhekele ukuzwela. Ngenxa yalokhu, ngaphezu kwempi yokulwa nokumelana, ukugcotshwa koshukela kanye nama-lipid egazini kuyancipha.

Ukudla

Ngokumelana ne-insulin, ukugcizelela ekudleni okuphansi kwe-carb ngaphandle kokubulawa yindlala. Kunconywa izinhlobo zokudla zohlobo oluthile, kufanele kube ka-5 kuye ku-7 ngosuku, kucatshangelwa ukudla okulula. Kubalulekile futhi ukuphuza inani elanele lamanzi, hhayi ngaphansi kwamalitha ayi-1.5 ngosuku.

Isiguli sivunyelwe ukudla ama-carbohydrate aphuza kancane. Kungaba:

1. Iporridge
2. Imikhiqizo ebhakiwe esekelwe kufulawa we-rye;
3. Imifino
4. Izithelo ezithile.

Ngokudla kwe-carb ephansi, isiguli akufanele:

• Ilayisi elimhlophe;
• Inyama enamafutha nenhlanzi;
• Wonke amnandi (ama-carbohydrate asheshayo);
• Manku;
• Ubhatata;
• Imikhiqizo Ebhemayo;
• Ibhotela;
• Amajusi
• Ibhotela nofulawa;
• Ukhilimu omuncu.

Konke ukudla kudliwa yisiguli kufanele kube nenkomba ephansi ye-glycemic. Leli gama liyinkomba yezinga lokuqhekeka kwemikhiqizo ye-carbohydrate ngemuva kokungena emzimbeni. Uma lesi sikhombisi somkhiqizo sincipha, kulapho sisebenza khona isiguli.

Ukudla ukulwa ne-insulin kwakhiwa kusuka kulokho kudla okunenkomba ephansi. Kuqabukela kakhulu ukudla okuthile nge-GI ephakathi. Indlela yokulungiselela umkhiqizo ngokuvamile ayinamthelela omncane ku-GI, kepha kukhona okuhlukile.

Isibonelo, izaqathi: lapho iluhlaza inkomba yayo ingama-35 futhi ingadliwa, kepha izaqathi ezibilisiwe zikhulu kakhulu i-GI futhi akunakwenzeka ngokuphelele ukuyidla.

Izithelo nazo zingadliwa, kepha awudingi ukudla ama-gram ayi-200 ngosuku. Akunakwenzeka ukulungiselela ujusi owenziwe ekhaya kubo, ngoba lapho uganga luchotshozwa, isikhunta siyanyamalala bese ujusi uthola i-GI enkulu kakhulu.

I-GI ingahlukaniswa ngezigaba eziningana:

1. Kufika kuma-50 - aphansi;
2. I-50-70 - i-avareji;
3. Ngaphezu kwama-70 kukhulu.

Kukhona okunye ukudla okungenayo i-glycemic index nhlobo. Kungenzeka yini ukuba ubadle ngokumelana ne-insulin? - cha. Cishe njalo, isidlo esinjalo sinokuqukethwe kwekhalori okuphezulu kakhulu, futhi awukwazi ukukudla ngokuphulwa kokuzwela kwe-insulin.

Kukhona futhi ukudla okunenkomba encane nokuqukethwe okukhulu kwama-khalori:

• Imbewu yelanga;
• Izikhwebu ze-chickpea;
• Amantongomane.

Umsoco wesiguli kufanele uhluka. Kumele ibe nenyama, izithelo, imifino. Ukudla okunoshukela kunconywa ukuthi kudliwe ngaphambi kuka 15:00. Isobho liphekwe kangcono kumhluzi wemifino, kwesinye isikhathi kuyamukeleka ukusebenzisa umhluzi wenyama wesibili.

Ukudla okune-carb ephansi, ungadla lezi zinhlobo zenyama:

1. Isibindi (inkukhu / inyama yenkomo);
2. Inkukhu yaseTurkey;
3. Inkukhu
4. Isilwane;
5. Inyama yemvundla;
6. Inyama yeQuail;
7. Izilimi.

Ukusuka ezinhlanzini ungahamba nge-pike, pollock ne-perch. Badinga ukudliwa okungenani amahlandla ama-2 ngesonto. Iphalishi elihlotshisiwe kahle. Zibilisiwe emanzini, azikwazi ukuthwalwa ngemvelaphi yezilwane.

Ungadla okusanhlamvu okunjalo:

• Irayisi elinsundu;
• Buckwheat
• Ibhali leParele;
• Yachka.

Kwesinye isikhathi ungaziphatha ku-pasta eyenziwe ngokhuni i-durum. Ungadla iqanda leqanda eli-1 ngosuku ngaphambi kweprotheni. Ekudleni, ungadla cishe lonke ubisi, ngaphandle kwalelo elinamaphesenti amakhulu wokuqukethwe kwamafutha. Ingasetshenziswa ekudleni ntambama.

Imikhiqizo elandelayo ikuhlu oluhlaza:

• Ushizi wekotishi;
• Ubisi
• Kefirs;
• Khilimu uze ufike kumaphesenti ayishumi;
• Ama-yogurts angenazimpawu;
• Tofu;
• I-Ryazhenka.

Isabelo sengonyama sokudla kufanele sibe nemifino. Ungenza isaladi noma isidlo eseceleni kubo.

Inkomba ephansi ye-glycemic kwimifino enjalo:

1. Garlic no-anyanisi;
2. Isitshalo seqanda
3. Ukhukhamba
4. Utamatisi
5. Ama-Pepper ezinhlobo ezahlukahlukene;
6. I-Zucchini;
7. Noma iyiphi iklabishi;
8. Amapisi amasha futhi omisiwe.

Isiguli empeleni asinqunyelwe kwizithako nezinongo. I-Oregano, i-basil, i-turmeric, isipinashi, i-parsley, i-dill noma i-thyme ingahluka ngokuphephile ezitsheni.

Kuhle ukufaka ekudleni kwakho:

• Ama-currants;
• Amaplamu;
• Amapheya
• Ama-raspberries;
• Ama-Blueberries
• Apula
• Amabhilikosi
• Ama-Nectarines.

Ungadla ukudla okuningi okuhlukahlukene ekudleni okune-carb ephansi. Ungesabi ukuthi okudlayo kuzoba ukungathandeki futhi kube yi-Mediocre.

Ukudlala imidlalo

Ochwepheshe bezokuzivocavoca bezemidlalo bakholelwa ukuthi ukusebenza ngokomzimba kuyindlela ephumelela kunazo zonke yokulwa nokulwa ne-insulin. Ngesikhathi sokuqeqeshwa, ukuzwela kwe-insulin kukhuphuka ngenxa yokunyuka kweglucose ngesikhathi sokuqothuka kwemicu yemisipha.

Ngemuva komthwalo, ubukhulu bokwehla, ngenkathi izinqubo zesenzo esiqondile se-insulin kwizakhi zemisipha ziqala. Ngenxa yemiphumela yayo ye-anabolic ne-anti-catabolic, i-insulin isiza ekwakheni ukuntuleka kwe-glycogen.

Ukubeka kalula, ngaphansi komthwalo, umzimba udonsa ama-molecule we-glycogen (ushukela) ngangokunokwenzeka futhi, ngemuva kokuqeqeshwa, umzimba uphela nge-glycogen. Umuzwa we-insulin uyanda ngenxa yokuthi izicubu azinawo amandla okugcina amanzi.

Lokhu kuyathakazelisa: odokotela batusa ukugxila ekuqeqesheni abantu abanesifo sikashukela sohlobo 2.

Ukusebenza kwe-Aerobic kuyindlela enhle yokulwa nokumelana ne-insulin. Ngesikhathi salomthwalo, ushukela udliwa ngokushesha okukhulu. Ukuzivocavoca okulinganiselwe noma okuphezulu kwe-Cardio kungakhulisa ukuzwela ngezinsuku eziyi-6 ezizayo. Ukuthuthuka okubonakalayo kuqoshwa ngemuva kwesonto lokuqeqeshwa okungenani nokusebenza okungama-2 Cardio kwangaphakathi.

Uma amakilasi ebanjwa isikhathi eside, amandla amahle angaqhubeka isikhathi eside. Uma ngandlela thile umuntu eshiya ngokungazelelwe ezemidlalo futhi agweme ukuzikhandla, ukumelana ne-insulin kuzobuya.

Umthwalo wamandla

Inzuzo yokuqeqeshwa kwamandla akuyona nje ukwandisa ukuzwela kwe-insulin, kodwa futhi nokwakha izicubu zomzimba. Kuyaziwa ukuthi izicubu zigxilisa kakhulu ama-molecule eglue hhayi kuphela ngesikhathi somthwalo uqobo, kodwa futhi nangemva kwawo.

Ngemuva kokuqeqeshwa kwamandla we-4, ngisho nangesikhathi sokuphumula, uzwela we-insulin uzonyuswa, futhi izinga le-glucose (inqobo nje uma ungadlanga ngaphambi kokulinganisa) lizokwehla. Lapho imithwalo ikhanya kakhulu, kuba ngcono inkomba yokuzwela.

Ukuphikisana ne-insulin kuqedwa kangcono yindlela ehlanganisiwe yokusebenza komzimba. Umphumela omuhle kakhulu urekhodwa ngokushintshana nokuqeqeshwa kwe-aerobic namandla. Ukwenza isibonelo, uya ejimini ngoMsombuluko, ngoLwesithathu, uLwesihlanu, nangoMsombuluko. Yenza i-Cardio ngoMsombuluko nangoLwesihlanu (ngokwesibonelo, ukugijimela, i-aerobics, ibhayisekili), futhi uvivinya umzimba ngomthwalo wangoLwesithathu nangeSonto.

Isiphetho

Ukumelana ne-insulin kungaphephile uma kukhula ngokubhekisele emuva ngemuva kwezinqubo ezinjengokufikisa noma ukukhulelwa. Kwezinye izimo, lesi simo sibhekwa njenge-metabolic pathology eyingozi.

Kunzima ukusho izizathu ngqo zokuqhamuka kwalesi sifo, kepha abantu abakhuluphele banqunyelwe kuso. Lokhu kungasebenzi kuvame ukuhambisana nezimpawu ezicacile.

Uma kungalashwa, ukwephulwa kokuzwela kwe-insulin kungadala isifo sikashukela nezifo ezahlukahlukene zesistimu yenhliziyo. Ukwelashwa kokungasebenzi kahle, kusetshenziswa imithi, ukusebenza ngokomzimba kanye nokudla okhethekile.