Ungayifaka kanjani i-Fraxiparin? Lo mbuzo uvame ukuphakama ezigulini obekelwe zona. Umphumela wemithi yesidakamizwa i-anticoagulant ne-antithrombotic.
Into esebenzayo kuyo yi-calcium nadroparin. Kwesinye isikhathi kuyenzeka ukuthi udokotela anikeze lesi sidakamizwa kowesifazane.
Ikakhulu ngesikhathi sokukhulelwa, i-Fraxiparin imiselwe ukuvikela ukugcwala kwegazi okwandayo, okungaholela ekuqhekekeni kwegazi. Futhi, umuthi ungasetjenziswa zombili ukuvikela izifo kanye nokuzelapha.
Ezinye iziguli ziphuza umuthi izinyanga eziyisishiyagalolunye. Manje-ke siyini lesi sidakamizwa, nokuthi ungasineka kanjani ngendlela efanele?
Izikimu
Izisebenzi zezikhungo zezokwelapha zithi lo muthi uphephe ngokuphelele, ngakho-ke awunakukhathazeka ngomonakalo empilweni. Ezinye iziguli ezizithatha, ziqaphele ukuthi emiyalweni yazo akukho mininingwane ngokusetshenziswa komuthi ngesikhathi sokukhulelwa.
Kuze kube manje, akukho cwaningo olwenziwe ngale ndaba. Iningi lochwepheshe lithi isizathu sinjengokulandelayo: le ncwajana ayinayo idatha entsha, njengoba ingabhalwanga iminyaka engamashumi amathathu.
Isixazululo sokuphatha subcutaneous of Fraxiparin
Lo muthi unikezwa kuphela ezimweni ezibucayi kakhulu, lapho kunengozi enkulu yezinkinga. Isibonelo, uma ungafaki umuthi ngesikhathi lapho kungekho-anticoagulant ngegazi elikhuphukayo. Ukuphuphuma kwezisu noma ukushona kwengane akukhishwa.
Uhlu lwe-contraindication, ukukhuphula kwezilonda zesisu noma i-duodenal ulcer, ukuphazamiseka okungathi sína kokujikeleza emehlweni, nezinye izifo zingafakwa. Ngokuqondene nendlela yokuphatha, isixazululo okukhulunywa ngaso siphathwa ngokungaziphathi.
Ngale nqubo, isiguli kufanele sibe sesimweni esivamile.
Umuthi kumele uklanyelwe ngaphansi kwesikhumba endaweni yezinyoni noma indawo engemuva kwesisu.
Kwethulwa ohlangothini ngalunye ngokulandelana: okokuqala ngakwesokunxele bese ngakwesobunxele.
Uma ufisa, ungangena endaweni yethanga. Inaliti ifakwe ngaphansi kwesikhumba endaweni yesimo se-perpendicular. Ngaphambi kokufakwa, isikhumba kufanele sicindezelwe kancane ku-crease encane.
Kwakhiwa endaweni ephakathi kwesithupha nokhokho abaphambili. Indawo yesibaya kufanele igcinwe kuyo yonke inqubo yokulawulwa kwezidakamizwa. Ngemuva komjovo, indawo lapho kwakusetshenziswe khona lo muthi akufanele ihlikihlwe.
Izici zokusebenzisa i-Fraxiparin ngokuya ngezinhloso:
- ngesikhathi sokuqalisa ukwelashwa okusebenzayo kokuthintela kwe-thromboembolism ngesikhathi sokungenelela kokuhlinzwa kwamathambo, umjovo wenziwa kusetshenziswa umjovo we-subcutaneous in volumes, ngokuya ngokubalwa kwesisindo somzimba wonke. Ngokuyinhloko, i-kilogram eyodwa yesisindo sesiguli idinga umthamo ofinyelela ku-39 IU anti-Xa. Cishe ngosuku lwesithathu noma lwesine ngemuva kokuhlinzwa, umthamo womuthi ungakhuphuka ufike kuma-45%. Umjovo wokuqala wesidakamizwa kufanele wenziwe amahora ayishumi nambili ngaphambi kokuhlinzwa. Kepha owesibili - ngemuva kwenkathi efanayo yesikhathi ngemuva kokuhlinzwa. Ngemuva kwalokhu, imijovo yezidakamizwa yenziwa ngaso sonke isikhathi kuze kube yilapho amathuba e-thrombosis, okubeka usongo olukhulu empilweni yeziguli, ancishiswe. Isikhathi sokwelashwa usebenzisa lo muthi izinsuku eziyishumi;
- ngesikhathi sokwelashwa kwe-thromboembolism ngesikhathi futhi ngokushesha ngemuva kokuhlinzwa, kuyelulekwa ukuthi kuphathwe isisombululo kumthamo we-0.3 ml noma i-2851 IU anti-Xa. Kufanele iklanywe ngomjovo ongabonakali. Umuthi uphathwa cishe amahora amathathu ngaphambi kokuhlinzwa noma ngemuva kwalokho kanye ngosuku. Ukwelapha kufanele okungenani izinsuku eziyisikhombisa. Ungahlala kuze kube yilapho ingozi eyandayo yokuqhekeka kwegazi inyamalala;
- iziguli ezisengozini ye-thrombosis, ehambisana nezifo ezithathelanayo zohlelo lokuphefumula, kanye nokuphefumula kanye nokwehluleka kwenhliziyo, umuthi unqunywa kanye ngosuku. Kunconywa ukungena ngaphansi kwesikhumba. Umthamo wesidakamizwa usethwa ngokuya ngesisindo sesiguli. Umuthi lo uphathwa ngaso sonke isikhathi sengozi yokuqhekeka kwegazi;
- ekwelapheni i-thromboembolism, imithi ene-anticoagulant isetshenziswa ngokushesha ngemuva kokuvela kwezimpawu zokuqala zalesi sifo. Ukuphathwa kwomuthi ngomjovo kwenziwa kuze kube kufinyelele izinkomba ezidingekayo zesikhathi se-prothrombin. Umuthi uphathwa ngendlela ecishe ibe kabili ngosuku. Umjovo kufanele wenziwe njalo emahoreni ayishumi nambili. Umthamo wesidakamizwa uncike kwisisindo sesiguli - udinga ukufaka umjovo we-87 IU anti-Xa ngekhilogremu.
Umthamo
Inani lezidakamizwa lincike kwesisindo somzimba. Ngesisindo esingama-50 kg noma ngaphansi, umthamo onconyelwe umuthi ngu-0,5 ml. Leli yivolumu elawulwa amahora ayishumi nambili ngaphambi kokuhlinzwa kanye nenani lesikhathi esilandelile ngemuva kwalo.
Kepha umthamo odinga ukujova kanye ngosuku izinsuku ezine ngemuva kokuhlinzwa u-0.3 ml.
Uma isisindo somzimba sehluka phakathi kwama-50-70 kg, lapho-ke udinga ukufaka umuthi ongu-0,3 ml wesikhathi esingamahora ayishumi nambili ngaphambi kokuhlinzwa nangemva kwaleyo sikhathi ngemuva kwawo.Kusukela ngosuku lwesine ngemuva kokuhlinzwa, umthamo womjovo owodwa womuthi ngu-0,4 ml.
Lapho isisindo singaphezu kwama-70 kg, umthamo onconywayo ngu-0,4 ml wengxenye yosuku ngaphambi nangemva kokuhlinzwa. Kepha umthamo weFraxiparin, ophekwa kanye ngosuku ngosuku lwesine ngemuva kokuhlinzwa, ungama-0,6 ml.
Isu lobuchwepheshe lokwazisa i-Fraxiparin esiswini: imithetho
Kuyadingeka ukukhipha umuthi esiswini. Akunconyelwe ukunikeza umjovo enkabeni nakulayini wesibambo.
Futhi, ungazifaki ezindaweni ezinamanxeba okulimala, izibazi namanxeba. Isithupha kanye nesandulelo sidinga ukwakha isibaya, okuphumela kulokho okubizwa ngunxantathu. Isihloko saso kufanele sibe phakathi kweminwe yakho.
Ngaphansi kwalesi sikhwama, hlinza umuthi ngakwesokunene. Akunasidingo sokuyeka isibaya ngesikhathi sokuphatha umuthi. Lokhu kufanele kwenziwe ngokushesha ngemuva kokukhipha isirinji. Akunconyelwe ukwengeza isiza somjovo.
Sebenzisa ngesikhathi sokukhulelwa
Ngokwezivivinyo zezilwane, kunenqwaba yemininingwane ethi izithako ezakha umuthi zidlulela kwi-placenta ziye e-fetus.
Ngakho-ke, ukusetshenziswa kwe-Fraxiparin ngesikhathi sokukhulelwa akunconywa, kepha kwezinye izikhathi kuyasetshenziswa. Kunezimo lapho inzuzo kamama idlula ingozi yengane engakazalwa.
Ngesikhathi sokuncelisa, ukusetshenziswa komuthi akuvunyelwe, ngoba izithako zawo zingadlula ubisi.Ngokuyisisekelo, ku-trimester yokuqala yokukhulelwa, umuthi awubekelwa ukwelashwa noma ukuvimbela noma yiziphi izifo.
Kepha ngolwesibili nolwesithathu ukusetshenziswa kwayo kungenzeka uma kungekho mibiko. Isidingo sokusebenzisa i-Fraxiparin ngesikhathi sokukhulelwa sichazwa iqiniso lokuthi i-placenta ihlala ikhula ngesikhathi sokukhulelwa, ngakho-ke, kuvela imithambo yegazi eminingi kuyo.
Ngokuqina kwegazi okuphezulu, i-plasma ingagxila ema-capillaries amancane.
Lokhu kunomthelela ekubonakala kwamaqhubu egazi, okuthi kamuva kuholele ekuphepheni komoya-mpilo.
Kwi-trimester yesithathu, izitsha ezinkulu ze-pelvis zidonswa ngokuqinile yisibeletho esandayo, okuholela ekuwohlokeni kokukhipha kwegazi kusuka emithanjeni yemilenze. Ngenxa yalokhu, igazi liqala ukujuluka, kuthi qhume igazi.
Ukubandakanyeka okubucayi kakhulu kwalesi simo i-embolism yamaphaphu, engabulala. Ngenxa yalokho, ingane nayo ngeke isinde.
Contraindication kanye nemiphumela engafunekiyo yomzimba kuyo
I-Fraxiparin iyikhambi elisebenzayo, elibonakaliswa isenzo esiqinile. Yingakho inohlu lwemiphumela emibi kanye ne-contraindication ukuze isetshenziswe.
Udokotela kumele asitadishe ngokucophelela lesi simo futhi ahlaziye ubungozi bokwamukelwa.
Umuthi awukwazi ukusetshenziselwa ukwaliwa, ukuswelakala kokuqina kwegazi, kanye nalapho kungekho khona umphumela wokuthola ukwelashwa ngezidakamizwa zeqembu le-antiplatelet.
Ngokuqondene nemiphumela emibi, ngemuva kokusetshenziswa kwomuthi, ukubukeka kokuqhuma, ukulunywa, i-urticaria, i-edema yeQuincke nokushaqeka kwe-anaphylactic kungenzeka. Ngokuqapha ngokweqile, kufanele isetshenziswe lapho kukhona khona ukungasebenzi kwesibindi.
Lokhu kusebenza futhi ekusebenzeni kabi kwezinso, ukuhamba kwegazi okulimazekile ezinhlamvini zamehlo, umfutho wegazi ophakeme, ukuhlangana komgudu wokugaya ukudla.
Kunefomu lethebhulethi lesidakamizwa. Kepha, kufanelekile ukuqaphela ukuthi ngaphambi kokuguqukela kukho, udinga ukubonana nodokotela wakho.
Ividiyo elusizo
Imiyalo yokuthi ungayifaka kanjani i-Fraxiparin nezinye izidakamizwa esiswini, kuvidiyo:
Kumele kuqashelwe ukuthi ukuvela kwe-edema encane endaweni yokujova kubhekwa njengokujwayelekile. Vele, asikho isizathu sokukhathazeka kuphela uma lokhu kungadali owesifazane. Okubalulekile: kuyenqatshelwe ngokuphelele ukuthi uzijova nge-Fraxiparin ngaphandle kwemvume kadokotela, ikakhulukazi ngesikhathi sokukhulelwa. Udokotela uqobo unelungelo lokuqokwa kuye.
