I-Augmentin 500 iyi-antibiotic ethandwayo enesibuko esikhulu sezenzo. Umuthi ulwa ngempumelelo nama-microorganisms amaningi we-pathogenic angama-hypersensitive ku-amoxicillin ne-clavulanic acid.
I-ATX
Ikhodi J01CR02.
I-Augmentin 500 iyi-antibiotic ethandwayo enesibuko esikhulu sezenzo.
Khipha amafomu nokwakheka
Umuthi ukhiqizwa ngendlela yamaphilisi ngomthamo wento esebenzayo 500 mg / 125 mg. Izithako ezisebenzayo yi-amoxicillin ne-clavulanic acid. Izithako ezingeziwe:
- i-magnesium stearate;
- isodium starch glycolate uhlobo A;
- i-silicon dioxide colloidal i-anhydrous;
- i-microcrystalline cellulose.
Ngaphezu kwalokho, umuthi ukhishwa ngendlela ye-powder yokulungiselela ukumiswa kokuphathwa komlomo kanye nesisombululo somjovo. Kepha izindlela ezinjalo zomuthi azithandwa kakhulu ngodokotela, futhi zibekelwe ikakhulukazi iziguli esibhedlela.
Ukumiswa kokuphathwa kwangaphakathi kunomuthi olandelayo: 125, 200, 400 mg, kanye nesisombululo se-intravenous: 500 noma 1000 mg.
Isenzo se-Pharmacological
I-Amoxicillin yi-ejenti elenziwa elenziwa ngama-antibacterial enobubanzi besenzo. Isebenza ngokulwa namagciwane amancane wegram-positive ne-gram-negative. Ngasikhathi sinye, i-amoxicillin iyakwazi ukudiliza ngaphansi kwesenzo se-β-lactamases, ngakho-ke isibuko lomsebenzi walesi sidakamizwa asidluleli kuma-microorganisms akhiqiza le enzyme.
I-izidakamizwa ze-amoxicillin ezisebenzayo yi-ejenti yokwenziwa ye-antibacterial enobubanzi besenzo.
I-Clavulanic acid iyi-β-lactamase inhibitor ehlobene nokwakheka kwama-penicillin futhi ekwazi ukwenza i-β-lactamases ehlukahlukene etholakala kuma-penicillin ne-cephalosporin ukumelana kwama-microorganisms.
I-Clavulanic acid iyasebenza ngokulwa ne-plasma β-lactamases, evame ukubangela ukumelana kwamagciwane. Ngenxa ye-clavulanic acid, kungenzeka ukuvikela i-amooticillin ekubhujisweni ngama-enzyme - β-lactamases. Ngaphezu kwalokho, isibuko se-antimicrobial se-Augmentin siyanda.
I-Pharmacokinetics
Izinto ezisebenzayo zishiya umzimba nomchamo ngendlela ye-penicillinic acid engasebenzi ngenani le-10-25% lomthamo othathwe.
Izinkomba zokusetshenziswa
Umuthi ubekelwe ukwelashwa kwalezi zinhlobo ezilandelayo zezifo:
- ipheshana lokuphefumula eliphezulu: i-tonsillitis evamile, i-sinusitis, imidiya ye-otitis;
- ipheshana lokuphefumula eliphansi: ukukhipha i-bronchitis engapheli, i-lobar pneumonia, i-bronchopneumonia;
- uhlelo lwe-genitourinary: cystitis, urethritis, pyelonephritis, izifo ze-gynecological, i-gonorrhea;
- isikhumba nezicubu ezithambile: i-cellulite, ukulunywa yizilwane, ama-abscesses acute kanye ne-phlegmon yesifunda sama-maxillofacial;
- ukutheleleka kwamathambo kanye nokuhlangana: osteomyelitis.
Futhi, umuthi usuzinzile ekwelashweni kokukhipha isisu nge-septic, ukuzala kanye ne-intra-isisu sepsis.
Ingasetshenziselwa isifo sikashukela?
Imiyalo esetshenziswayo ikhombisa ukuthi iziguli ezinesifo sikashukela zingathatha i-Augmentin, kepha kuphela ngokuqapha. Ngesikhathi sokuhamba kwenkambo yokwelapha, ukuqapha amazinga kashukela egazini kuyadingeka.
Contraindication
Umuthi okwenziwe ngamathebulethi awuvunyelwe ukusetshenziswa ezimweni ezilandelayo:
- ukusabela komzimba ezingxenyeni zomuthi;
- I-hypersensitivity kwamanye ama-beta-lactam ama-antibiotic;
- umsebenzi wesibindi noma okhubazekile kwesibindi;
- izingane ezingaphansi kweminyaka engu-12 noma iziguli ezinesisindo esingaphansi kwama-40 kg.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Umuthi akufanele usetshenziswe ngesikhathi sokuzala kwengane, ngoba Izifundo eziningi ngemiphumela ye-antibiotic ku-fetus zenziwa. Umuthi ungabhekelwa kwabesifazane ngesikhathi sokuqunjelwa, kepha ngokuthuthukiswa kwemiphumela engathandeki, ukwelashwa kuzofanela kuyekwe.
Umuthi akufanele usetshenziswe ngesikhathi sokuzala kwengane, ngoba Izifundo eziningi ngemiphumela ye-antibiotic ku-fetus zenziwa.
Ungayithatha kanjani i-Augmentin 500?
Ngaphambi kokuthatha umuthi, kubalulekile ukunquma ukuzwela emithini ye-microflora, okuholele ekukhuleni kwesifo esigulini. Imithamo isungulwa ngawodwana futhi incike ekujuleni kwenqubo ye-pathological, indawo ukutheleleka kanye nokuzwela kwe-pathogen.
Abantu abadala nezingane ezineminyaka engu-12 ubudala ezinesisindo somzimba ezingaphezu kwama-40 kg zinqunywa ithebhulethi e-1 izikhathi ezintathu ngosuku, inqobo nje uma inqubo yokutheleleka iqhubeka ngobunzima nobunzima bokulinganisela. Ezimweni ezinzima ze-pathology, ezinye izindlela ze-Augmentin zikhonjisiwe.
Inkambo encane kakhulu yokwelashwa izinsuku eziyi-5. Ngemuva kwamaviki amabili wokwelashwa, udokotela kumele ahlaziye isimo somtholampilo ukuze anqume ngokuqhubeka kwenkambo yokwelashwa kwe-antibacterial.
Iziguli ezingaphansi kweminyaka engu-12 ubudala zikhonjiswa ngokulungiselela isiraphu. Umthamo owodwa kuncike eminyakeni yobudala:
- Iminyaka engu-7-12 - 10 (0.156 g / 5 ml) noma i-5 ml (0.312 g / 5 ml);
- Iminyaka engu-2-7 - 5 ml (0.156 g / 5 ml).
Imiphumela emibi
Imicimbi emibi ihlala yenzeka lapho umthamo womuthi ukhuphuka.
Amapheshana wesisu
Isicanucanu, ukugabha, isisu.
Kusuka ohlelweni lwegazi nolwe-lymphatic
I-leukopenia eguqukayo.
Isistimu yezinzwa ephakathi
Isiyezi, i-migraine.
Kusuka ohlelweni lomchamo
I-interstitial nephritis, i-hematuria ne-crystalluria.
Uhlelo lokugonywa
I-Angioedema, i-anaphylaxis, i-serum syndrome ne-vasculitis.
Isibindi nepheshana elihlanganisiwe
Ukwanda okulinganiselayo ekuqoqweni kwama-enzyme wesibindi ALT / AST.
Imiyalo ekhethekile
Ngaphambi kokuqala ukwelashwa, udokotela kufanele aqoqe umlando wezokwelapha onemininingwane ohlanganisa ukusabela kwangaphambilini kwama-penicillin, cephalosporins, noma ezinye izidakamizwa ze-beta-lactam.
Ngaphambi kokuqala ukwelashwa kwe-Augmentin, udokotela kufanele aqoqe umlando wezokwelapha onemininingwane.
Ukuhambisana notshwala
Kuyinto engathandeki ukusebenzisa i-Augmentin ngotshwala lokhu kugcwele umthwalo owengeziwe esibindini nasezinso.
Umthelela ekhonweni lokulawula izindlela
I-ejenti elwa ne-antibacterial ingadala isiyezi, ngakho-ke phakathi nesikhathi sokwelashwa kuzodingeka wenqabe ukushayela imoto futhi usebenze ngamasu ayinkimbinkimbi.
Sebenzisa ebudaleni
Kubantu beminyaka yobudala, ukuncipha komthamo womuthi akudingekile. Uma iziguli zikhubazekile ukusebenza kwe-renal, khona-ke inqubo yomuthi iyaguqulwa ngudokotela.
Umthamo wezingane
Izingane ezifika eminyakeni eyi-12 ubudala sezisungule umuthi ngendlela yokumiswa. Umthamo wayo unqunywa kucatshangelwa ubudala besiguli.
Iziguli ezinenkinga yezinso umsebenzi
Ukulungiswa komthamo kusekelwe kumthamo ophakanyisiwe ophezulu kanye nenani lokucaciswa kwe-creatinine.
Iziguli ezingasebenzi kahle isibindi
Ukwelashwa kwenziwa ngokuqapha, kuyadingeka ukubheka njalo ukusebenza kwesibindi.
Ukweqisa
Izimpawu zokweqisa ngale ndlela yilezi ezilandelayo:
- usizi esiswini, ukuthopha, isisu, isicanucanu, ukuhlanza;
- ukwehla kwesikhumba, ukubambezela ukushaya kwenhliziyo nokuqina;
- iminyakazo
- izimpawu zokulimala kwezinso.
Ngokuthuthukiswa kwalezi zimpawu, isiguli kufanele siyeke ukuthatha i-antibiotic, sithintane nodokotela ukuze anikeze ukwelashwa okusobala. Esibhedlela, isiguli siyogezwa isisu, sinikezwe i-sorbent bese sihlanza igazi sisebenzisa i-hemodialysis.
Ukuxhumana nezinye izidakamizwa
Ungasebenzisi i-Augmentin ngokuhlanganiswa ne-Probenecid. Uma uhlanganisa i-antibiotic ne-Allopurinol, khona-ke kukhona ingozi yokungezwani komzimba. Inhlanganisela yesidakamizwa esivumelanayo ne-methotrexate yandisa umphumela onobuthi owokugcina.
Analogs of Augmentin 500
U-Augmentin unesakhiwo esifanayo ne-Amoxiclav, futhi indlela yokusebenza isebenza ngokufana neSuprax.
Imibandela yekhefu lekhemisi
Ngokusebenzisa umuthi.
Intengo
Izindleko ezijwayelekile zesidakamizwa ama-ruble angama-250-300.
Izimo zokugcina i-Augmentin 500
Gcina umuthi emazingeni okushisa angaphansi kuka- + 25 ° C, endaweni eyomile futhi emnyama engafinyeleleki ezinganeni.
Impilo yeshelf umuthi
Ungasebenzisa i-antibiotic iminyaka emi-3 kusukela ngosuku lokukhiqizwa.
Ukubuyekezwa kwe-Augmentin 500
Odokotela
UNikolay, oneminyaka engama-43 ubudala, uSevastopol: "Ngivame ukusebenzisa lesi sidakamizwa esilimaza umzimba enkambisweni yami yezokwelapha. Ngiyinikeza ukwelashwa kwezifo zepheshana lokuphefumula eliphezulu. Ngokwezinzuzo, kufanele kuqashelwe ukuthi kusebenza kahle kakhulu futhi akunakho ukuxhomekeka kwezidakamizwa, kepha umuthi unezinkinga: intengo ephezulu kanye nengozi eyandayo ukuthuthukiswa kokuphendula okungahambi kahle. "
USvetlana, oneminyaka engama-32, uMagnitogorsk: "Nginikeza lo muthi ukwelashwa kwe-pathologies esithathelwanayo yohlelo lokuphefumula ezinganeni. Nginikeza umuthi ngendlela yesiraphu enambitheka nephunga elimnandi. Iziguli zami ezincane ziyithatha ngentokozo. Uma ngichaza umuthi olwa namagciwane emthanjeni ofanele bese ulandela. ngenxa yesimo sesiguli, ubungozi bezimpawu ezimbi buyancishiswa, bese imiphumela emihle ibonwa vele ngosuku lwesithathu lokwemukelwa. "
Gcina umuthi emazingeni okushisa angaphansi kuka- + 25 ° C, endaweni eyomile futhi emnyama engafinyeleleki ezinganeni.
Iziguli
USergey, oneminyaka engu-35, eMoscow: "Kutholakale ukuthi kutholakale isifo se-gonorrhea ngenkathi kutholwa i-smear kusuka ku-urethra. Amaphilisi ka-Augmentin anqunywa njengengxenye yokwelapha okuyinkimbinkimbi. Izifundo zaqhubeka izinsuku eziyi-7, ngemuva kwalokho zonke izinkomba zesifo zaqedwa."
U-Olga, oneminyaka engama-24, uNizhny Novgorod: "Ngathola ukuzalwa okunzima, okwathi ngemuva kwalokho kwaqalwa i-sepsis. Odokotela banquma ikhambi le-intravenous antibiotic. Ngayifaka amahlandla ama-2 ngosuku izinsuku ezingama-5. Ngemuva kokuqeda izifundo, ngazizwa ngisezingeni elifanele."
UVladimir, oneminyaka engama-45, eYekaterinburg: "Eminyakeni embalwa edlule bathola i-pyelonephritis. U-Augmentin wasetshenziselwa ukwelapha i-pathology, ngoba wayekhathazekile ngokushisa komzimba okuphezulu kanye nokulimala esifundeni se-lumbar. Ngemuva kwezinsuku ezi-2 zokuphuza amaphilisi, wazizwa ekhululekile. Ngaphezu kwalokho, wahlanganisa umuthi olwa nemithi yokubulala amagciwane. Izithasiselo ezisebenzayo, kepha akubanga nazimpawu zibonakalayo. "